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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Clarigard 250 Tablet is used to treat a wide range of bacterial infections, including chest infections such as bronchitis and pneumonia, skin problems such as cellulitis (potentially serious bacterial skin infection, the affected skin appears swollen and red and is typically painful and warm to the touch), and ear infections. Besides this, it is also used in combination with other medicines to treat duodenal ulcers caused by H. pylori. It contains Clarithromycin, which inhibits the growth of bacteria. It may cause some common side effects, such as nausea, diarrhoea, vomiting, loss of appetite, bloating, indigestion, headaches and difficulty sleeping. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Manufacturer/Marketer :

Macleods Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Clarigard 250 Tablet

Clarigard 250 Tablet is used to treat a wide range of bacterial infections, including chest infections such as bronchitis and pneumonia, skin problems such as cellulitis (potentially serious bacterial skin infection, the affected skin appears swollen and red and is typically painful and warm to the touch), and ear infections. Besides this, Clarigard 250 Tablet is also used in combination with other medicines to treat duodenal ulcers caused by H. pylori.

Clarigard 250 Tablet contains Clarithromycin (antibiotic). It inhibits the protein synthesis process required for the growth of the bacterial cell. As a result, bacterial cells are not able to reproduce and grow. Thus, Clarigard 250 Tablet helps prevent infections.

Clarigard 250 Tablet should only be if your doctor has prescribed you. Clarigard 250 Tablet should not be stopped even if you feel better as it is an antibiotic medication, and completing the full course is necessary; otherwise, the infection might re-appear in a more severe form. Like all medicines, Clarigard 250 Tablet may cause some common side effects, including feeling sick (nausea), diarrhoea and being sick (vomiting), losing your appetite, bloating and indigestion, headaches and difficulty sleeping. These side effects are temporary and may get resolved after some time; however, if this side persists, let your doctor know about this if you notice any sudden wheeziness, tightness in the chest or throat, difficulty in breathing, swelling of the eyelids, face or lips, rash or itching (especially affecting your whole body) STOP TAKING your medicine and go to a doctor immediately.

Do not take Clarigard 250 Tablet if allergic to azithromycin, other macrolide antibiotics, or any components present in Clarigard 250 Tablet . Clarigard 250 Tablet isn't normally recommended during pregnancy and while breastfeeding. But your doctor may prescribe it if the benefits of taking it are greater than the risks. Do not consume alcohol as it may cause excessive drowsiness when taken along with Clarigard 250 Tablet . Before using the Clarigard 250 Tablet , tell your doctor if you ever had an allergy to Clarigard 250 Tablet have kidney problems, liver problems, swollen food pipe (oesophagitis), lupus disease (an autoimmune disease), or muscle disease (myasthenia gravis). Do not drink alcohol with Clarigard 250 Tablet as it may increase the unpleasant side effects like drowsiness and dizziness.

Uses of Clarigard 250 Tablet

Treatment of Bacterial infections

Directions for Use

Tablet/capsule: Swallow it as a whole with water; do not crush, break or chew it.Dispersible Tablet: Check the label for directions before use. Disperse the tablet in the prescribed amount of water and swallow the contents. Do not crush, chew or swallow as a whole.

Medicinal Benefits

Clarigard 250 Tablet is a type of macrolide class of antibiotic which is effective against a wide range of bacteria, including gram-negative and gram-positive bacteria, anaerobes, and some parasites (like Balantidium coli and Entamoeba species). It is prescribed for treating various bacterial infections, including chest infections such as pneumonia, skin problems such as cellulitis, and ear infections; on the other hand, It is also used in combination with other medicines to treat duodenal ulcers caused by H. pylori (Helicobacter pylori). Clarigard 250 Tablet  is sometimes used by people who have an allergy to penicillin and antibiotics similar to penicillin, such as amoxicillin.

How Clarigard 250 Tablet Works

Clarigard 250 Tablet contains Clarithromycin (antibiotic). It inhibits the protein synthesis process required for the growth of the bacterial cell. As a result, bacterial cells are not able to reproduce and grow. Thus, Clarigard 250 Tablet helps prevent infections.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Clarigard 250 Tablet

  • Headache

  • Diarrhoea

  • Being sick (vomiting)

  • Nausea (feeling sick)

  • Loss of appetite

  • Taste change

  • Bloating

  • Indigestion

  • Abdominal pain

  • Insomnia (difficulty sleeping)

What if I have taken an overdose of Clarigard 250 Tablet

Do not take more than the prescribed dose of Clarigard 250 Tablet as it may cause overdose. The symptoms of overdose include diarrhoea, vomiting, nausea and stomach pain. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Iron and antacid (like magnesium hydroxide and aluminium hydroxide) may bind to Clarigard 250 Tablet in the gastrointestinal tract, lowering its efficiency. So, a gap of at least 2 hours should be maintained between intake of Clarigard 250 Tablet and iron supplements and antacids. Besides this, in some cases, the use of Clarigard 250 Tablet causes antibiotic-associated diarrhoea. Clarigard 250 Tablet may cause sensitive skin to sunlight and ultraviolet rays, causing an exaggerated sunburn reaction. Hence it is advisable to apply sunscreen before going outside. Its use has also been associated with an increased risk of fungal skin infections like (vaginal candidiasis - thrush). Tetracycline and Clarigard 250 Tablet can form a stable calcium complex in bone-forming tissue, thereby affecting the growth of fibula bones in young children and bone development in the foetus. Using a Clarigard 250 Tablet with isotretinoin should be avoided as it has been reported to cause pseudotumor cerebri (increased pressure inside the brain). Long-term use of Clarigard 250 Tablet may affect your blood, kidney, and liver health, so yearly diagnostics test of these parameters is recommended.

Drug-Drug Interactions

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ClarithromycinMesoridazine
Critical
ClarithromycinTolvaptan
Critical

Drug-Drug Interactions

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ClarithromycinMesoridazine
Critical
How does the drug interact with Clarigard 250 Tablet 10's:
Co-administration of Clarigard 250 Tablet 10's and Mesoridazine may increase the risk of an irregular heart rhythm.

How to manage the interaction:
Co-administration of Clarigard 250 Tablet 10's and Mesoridazine can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
ClarithromycinTolvaptan
Critical
How does the drug interact with Clarigard 250 Tablet 10's:
When Tolvaptan and Clarigard 250 Tablet 10's are taken together, may significantly increase the blood levels and effects of Tolvaptan.

How to manage the interaction:
There may be a possibility of interaction between Tolvaptan and Clarigard 250 Tablet 10's, but it can be taken if prescribed by a doctor. If you notice any of these signs -difficulty swallowing, trouble speaking, muscle weakness, trouble controlling body movements, confusion, mood changes, seizures, call a doctor right away. Do not stop using any medications without a doctor's advice.
ClarithromycinDronedarone
Critical
How does the drug interact with Clarigard 250 Tablet 10's:
When Dronedarone is taken with Clarigard 250 Tablet 10's, can increase the blood levels of dronedarone and cause an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Clarigard 250 Tablet 10's with Dronedarone can result in an interaction, it should be taken only if a doctor has advised it. However, if you experience dizziness, lightheadedness, fainting, shortness of breath, or heart palpitation, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
ClarithromycinNaloxegol
Critical
How does the drug interact with Clarigard 250 Tablet 10's:
When Naloxegol is taken with Clarigard 250 Tablet 10's, the amount of Naloxegol in the blood can go up.

How to manage the interaction:
Co-administration of Clarigard 250 Tablet 10's and Naloxegol can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like sweating, tearing, runny nose, chills, diarrhea, abdominal pain, anxiety, insomnia, irritability, restlessness, and yawning, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
ClarithromycinZiprasidone
Critical
How does the drug interact with Clarigard 250 Tablet 10's:
Taking Clarigard 250 Tablet 10's with Ziprasidone can increase the risk of irregular heart rhythm.

How to manage the interaction:
Co-administration of Clarigard 250 Tablet 10's and Ziprasidone can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
ClarithromycinAstemizole
Critical
How does the drug interact with Clarigard 250 Tablet 10's:
When Astemizole is taken with Clarigard 250 Tablet 10's, it can cause a decrease in the metabolism of Astemizole.

How to manage the interaction:
Taking Clarigard 250 Tablet 10's with Astemizole is not recommended, please consult your doctor before taking it.
ClarithromycinErgotamine
Critical
How does the drug interact with Clarigard 250 Tablet 10's:
When Ergotamine is taken with Clarigard 250 Tablet 10's, the amount of Ergotamine in the blood can go up.

How to manage the interaction:
Taking Clarigard 250 Tablet 10's with Ergotamine can result in an interaction, it should be taken only if a doctor has advised it. However, if you experience abdominal pain, nausea, vomiting, numbness or tingling, muscle pain or weakness, blue or purple discoloration of fingers or toes, pale or cold skin, chest pain or tightness, irregular heartbeat, severe headache, shortness of breath, blurred vision, confusion, and/or slurred speech, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
ClarithromycinColchicine
Critical
How does the drug interact with Clarigard 250 Tablet 10's:
Coadministration of colchicine with Clarigard 250 Tablet 10's may increase the blood levels of colchicine, increasing the risk of serious side effects.

How to manage the interaction:
Taking Colchicine with Clarigard 250 Tablet 10's is not recommended, they can be taken together if advised by your doctor. However, contact your doctor if you experience abdominal pain, nausea, vomiting, diarrhea, fever, muscle pain, weakness, fatigue, and/or numbness or tingling in your hands and feet. Do not stop taking any medications without consulting a doctor.
ClarithromycinQuinidine
Critical
How does the drug interact with Clarigard 250 Tablet 10's:
When Quinidine is taken with Clarigard 250 Tablet 10's, can increase the blood levels and effects of Quinidine. This may increase the risk of an irregular heart rhythm.

How to manage the interaction:
Co-administration of Clarigard 250 Tablet 10's and Quinidine can lead to an interaction, it can be taken if advised by a doctor. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or fast or pounding heartbeats. However, if you experience any symptoms like headache, confusion, vomiting, diarrhea, ringing in the ears, hearing loss, blurred or double vision, or sensitivity to light, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
ClarithromycinFlibanserin
Critical
How does the drug interact with Clarigard 250 Tablet 10's:
When Flibanserin is taken with Clarigard 250 Tablet 10's, it can slow down the way Flibanserin is broken down in the body.

How to manage the interaction:
Co-administration of Clarigard 250 Tablet 10's and Flibanserin can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like excessive drowsiness and decreases in blood pressure that can lead to dizziness, lightheadedness, or fainting, consult a doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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CLARITHROMYCIN-250MGGrapefruit and Grapefruit Juice
Mild

Drug-Food Interactions

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CLARITHROMYCIN-250MGGrapefruit and Grapefruit Juice
Mild
Common Foods to Avoid:
Grapefruit Juice

How to manage the interaction:
Grapefruit juice may delay the gastrointestinal absorption of Clarigard 250 Tablet 10's. Avoid grapefruit juice while on treatment with Clarigard 250 Tablet 10's.

Diet & Lifestyle Advise

  • Probiotics and prebiotics can also help to reduce the side effects of antibiotics.

  • Include more fibre-enriched food in your diet, as it can be easily digested by your gut bacteria, which helps stimulate their growth. Thus, fibre foods may help restore healthy gut bacteria after a course of antibiotics. Whole grains like whole-grain bread and brown rice should be included in your diet. 

  • Eating grapefruit during antibiotics treatment can prevent the body from utilizing Clarigard 250 Tablet properly. So, avoid intake of grapefruit or grapefruit juice with the antibiotic. 

  • Avoid taking too much calcium, iron-enriched foods and drinks as it might affect the working of Clarigard 250 Tablet . 

  • Avoid intake of alcoholic beverages with Clarigard 250 Tablet as it can make you dehydrated and affect your sleep. This can make it harder for your body to aid the Clarigard 250 Tablet in fighting off infections.

Habit Forming

No

Therapeutic Class

ANTI- BACTERIALS

Clarigard 250 Tablet Substitute

Substitutes safety advice
  • Claribid 250 Tablet 10's

    24.08per tablet
  • Clarinova-250 Tablet 10's

    18.63per tablet
  • Cloff 250 Tablet 10's

    by AYUR

    24.08per tablet
  • Claribid 250 DS Combipack Fruit Punch Suspension 30 ml

    by AYUR

    7.49per tablet
  • Clarbact 250 Tablet 4's

    24.07per tablet
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Alcohol

Unsafe

Clarigard 250 Tablet should not be taken until prescribed if you are taking alcohol. Keep your doctor informed if you drink alcohol.

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Pregnancy

Caution

Clarigard 250 Tablet should be used in pregnant women only if clinically needed, and the benefits outweigh the risks.

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Breast Feeding

Caution

Let your doctor know if you are a nursing mother before taking Clarigard 250 Tablet ; your doctor will decide whether Clarigard 250 Tablet can be taken by breastfeeding mothers or not.

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Driving

Unsafe

Not enough scientific data available for Clarigard 250 Tablet , hence it is advised to consult your doctor.

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Liver

Caution

Clarigard 250 Tablet to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Clarigard 250 Tablet to be taken with caution, especially if you have a history of kidney diseases/conditions. The dose may have to be adjusted by your doctor.

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Children

Safe if prescribed

Clarigard 250 Tablet can be given safely to children in the form of suspension only, dose to be adjusted and recommended by a child specialist only.

FAQs

Clarigard 250 Tablet is used to treat bacterial infections, including chest infections, skin infections, and ear infections. Besides this, Clarigard 250 Tablet is also used in combination with other medicines to treat duodenal ulcers caused by H. pylori.
Clarigard 250 Tablet contains Clarithromycin (antibiotic). It inhibits the protein synthesis process required for the growth of the bacterial cell. As a result, bacterial cells are not able to reproduce and grow. Thus, Clarigard 250 Tablet helps in the prevention of infections.
You should avoid taking iron supplements, multivitamins, calcium supplements, antacids, or laxatives within 2 hours before or after taking Clarigard 250 Tablet . Avoid taking any other antibiotics containing Clarigard 250 Tablet unless your doctor has prescribed you.
After taking antibiotics such as Clarigard 250 Tablet , some people get thrush, a fungal infection. This is due to the fact that antibiotics kill the regular, harmless bacteria that serve to protect you from thrush.
Clarigard 250 Tablet treats only bacterial infections. It will not work for viral infections (such as common cold, flu).
No, Clarigard 250 Tablet is a macrolide antibiotic. It can be taken by people who are allergic to penicillin with doctor advice only.
Side-effects are rare with Clarigard 250 Tablet and do not usually last long. They will get better after a day or two. if those side effects persist reach out to the doctor immediately.​
No, Clarigard 250 Tablet should not be stopped even if you feel better as it is an antibiotic medication and completing the full course if very necessary; otherwise, the infection might re-appear in a more severe form.

Country of origin

India

Manufacturer/Marketer address

Atlanta Arcade, Marol Church Road, Andheri (East), Mumbai - 400059, INDIA.
Other Info - CLA0512

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