Tolperisone+nimesulide
About Tolperisone+nimesulide
Tolperisone+nimesulide is a skeletal muscle relaxant which is used to treat painful muscle spasms associated with musculoskeletal conditions such as rigidity, tension, stiffness, and skeletal muscle spasms.
Tolperisone+nimesulide contains Tolperisone and Nimesulide as its active components. Tolperisone relaxes muscles. It relieves stiffness or muscle spasms by working on the brain and spinal cord areas. Nimesulide acts by blocking enzymes that cause inflammation, reducing pain and inflammatory effects. Additionally, it prevents the breakdown of cartilage and reduces cytokine formation.
Common side effects of Tolperisone+nimesulide include headache, muscular weakness, nausea, vomiting, diarrhoea, abdominal pain, dizziness, and skin rashes. However, most of these side effects are temporary and do not require medical attention. If they persist or worsen, contact the doctor immediately.
Inform your doctor if you are allergic to any of its components before starting the treatment with Tolperisone+nimesulide. Contact a doctor if you are pregnant; it is unknown whether Tolperisone+nimesulide may affect the fetus. Avoid taking Tolperisone+nimesulide while breastfeeding. Do not give Tolperisone+nimesulide to children below 12 years. Before receiving the treatment, talk to your doctor if you have any pre-existing medical conditions or liver/kidney diseases.
Uses of Tolperisone+nimesulide
Medicinal Benefits
Tolperisone+nimesulide belongs to a group of medications called 'skeletal muscle relaxants’ used to treat painful muscle spasms associated with musculoskeletal conditions such as rigidity, tension, stiffness, and skeletal muscle spasms. It works by blocking the channels in the spinal cord and preventing the release of chemical messengers from afferent neurons. It functions as a central muscle relaxant. It enhances blood flow to the skeletal muscles, which decreases the release of pain-causing chemicals. Nimesulide blocks enzymes that cause inflammation, reducing pain and inflammatory effects. It also prevents cartilage breakdown.
Directions for Use
Swallow Tolperisone+nimesulide with a glass of water. Do not crush, chew, or break it.
Storage
Side Effects of Tolperisone+nimesulide
- Headache
- Muscular weakness
- Nausea
- Vomiting
- Diarrhoea
- Abdominal pain
- Dizziness
- Skin rashes
Drug Warnings
Before starting treatment with Tolperisone+nimesulide, inform your doctor if you are allergic to any of its active components. Also, inform about all the medical history, kidney/liver, or heart issues. Contact a doctor if you are pregnant or planning to become pregnant. Avoid taking Tolperisone+nimesulide while breastfeeding and contact a doctor immediately. Do not give Tolperisone+nimesulide to children below 12 years.
Drug Interactions
Drug-Drug Interactions: Tolperisone+nimesulide may interact with skeletal muscle relaxant (methocarbamol), fabric acid derivative (fenofibrate), NSAID (salicylic acid), anticonvulsant (valproic acid), sulfonylurea (tolbutamide), antimetabolite (methotrexate), diuretic (furosemide), anticoagulant (warfarin), immunosuppressant (cyclosporine), and bronchodilator (theophylline).
Drug-Food Interactions: No interactions found.
Drug-Disease Interactions: Inform your doctor if you have myasthenia gravis, hypersensitivity, and stomach issues.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
cautionAvoid consuming alcohol while on treatment with Tolperisone+nimesulide as it may increase tye risk of serious side effects.
Pregnancy
unsafeTolperisone+nimesulide is not recommended in pregnancy, especially in the first trimester, as it may cause birth abnormalities in the newborn baby.
Breast Feeding
unsafeTolperisone+nimesulide is not recommended for use in breastfeeding women.
Driving
safeTolperisone+nimesulide may sometimes cause dizziness; hence, avoid driving or doing activities requiring concentration.
Liver
cautionIf you have liver problems, inform your doctor before taking Tolperisone+nimesulide. It is not recommended for patients with severe liver impairment.
Kidney
cautionIf you have kidney problems, inform your doctor before taking Tolperisone+nimesulide.
Children
unsafeTolperisone+nimesulide is not recommended in children below 12 years due to a lack of information.
Habit Forming
Diet & Lifestyle Advise
- Stay hydrated by drinking water throughout the day, especially during and after exercise.
- Avoid drinks with caffeine or alcohol.
- Gently stretch your muscles before and after any activity to avoid muscle pain or stiffness.
- Stretch before bed or do light exercises like pedalling on a stationary bike for a few minutes to help prevent cramps while you sleep.
- To reduce muscle soreness, include vitamin C-rich foods such as oranges, strawberries, and bell peppers in your diet.
Special Advise
- During the treatment of Tolperisone+nimesulide, regular monitoring of the kidney/liver is advised.
Patients Concern
Disease/Condition Glossary
Musculoskeletal pain: It is a pain that affects muscles, ligaments, tendons, and bones. The most common symptoms of musculoskeletal pain include fatigue, sleep disturbances, and pain, which may vary for everyone. Injuries are the common cause of musculoskeletal pain causing acute (sudden) or chronic pain (long-term) in certain conditions like arthritis, gout, osteoporosis, osteomyelitis (bone infection), muscle bruises, bone fractures, bone bruises, joint dislocation, sprains, torn muscles, or tendons.
FAQs
Tolperisone+nimesulide is used to treat painful muscle spasms associated with musculoskeletal conditions such as rigidity, tension, stiffness, and skeletal muscle spasms.
Tolperisone+nimesulide contains Tolperisone and Nimesulide as its active components. Tolperisone relaxes muscles. It relieves stiffness or muscle spasms by working on the brain and spinal cord areas. Nimesulide acts by blocking enzymes that cause inflammation, reducing pain and inflammatory effects. Additionally, it prevents the breakdown of cartilage and reduces cytokine formation.
Tolperisone+nimesulide causes side effects such as headache, muscular weakness, nausea, vomiting, diarrhoea, abdominal pain, dizziness, and skin rashes. If these side effects persist or worsen, contact the doctor immediately.
Tolperisone+nimesulide may cause drowsiness, as it is one of its side effects. However, if you suspect the effect persists, please consult a doctor.
You are not recommended to stop taking Tolperisone+nimesulide even if you feel better, as it can cause unwanted side effects. Always consult a doctor before discontinuing Tolperisone+nimesulide.
