RIFAMPICIN+ETHAMBUTOL+ISONIAZID+PYRIDOXINE+PYRAZINAMIDE
About
RIFAMPICIN+ETHAMBUTOL+ISONIAZID+PYRIDOXINE+PYRAZINAMIDE belongs to the group of medicines called anti-tuberculosis drugs primarily used to treat tuberculosis (TB). Tuberculosis is an infectious disease that mainly affects the lungs but can also spread to other body parts such as kidneys, brain, spine, and bone marrow.
RIFAMPICIN+ETHAMBUTOL+ISONIAZID+PYRIDOXINE+PYRAZINAMIDE contains Rifampicin, Ethambutol, Isoniazid, Pyridoxine and Pyrazinamide. RIFAMPICIN+ETHAMBUTOL+ISONIAZID+PYRIDOXINE+PYRAZINAMIDE works by killing the bacteria named Mycobacterium tuberculosis, which causes TB (tuberculosis). Thus, it helps treat tuberculosis.
In some cases, RIFAMPICIN+ETHAMBUTOL+ISONIAZID+PYRIDOXINE+PYRAZINAMIDE may cause side effects such as nausea, vomiting, stomach pain, headache, and diarrhoea. Most of these side effects may not require medical attention and will resolve gradually. However, you are advised to talk to the doctor if the side effects persist or worsen.
Consult the doctor before taking RIFAMPICIN+ETHAMBUTOL+ISONIAZID+PYRIDOXINE+PYRAZINAMIDE if you are pregnant. Avoid breastfeeding while taking RIFAMPICIN+ETHAMBUTOL+ISONIAZID+PYRIDOXINE+PYRAZINAMIDE as it may pass into breast milk. RIFAMPICIN+ETHAMBUTOL+ISONIAZID+PYRIDOXINE+PYRAZINAMIDE is not recommended for use in children. RIFAMPICIN+ETHAMBUTOL+ISONIAZID+PYRIDOXINE+PYRAZINAMIDE may cause dizziness, so drive only if you are alert. Keep the doctor informed about your health condition and medications to rule out any interactions/side effects.
Uses of RIFAMPICIN+ETHAMBUTOL+ISONIAZID+PYRIDOXINE+PYRAZINAMIDE
Medicinal Benefits
RIFAMPICIN+ETHAMBUTOL+ISONIAZID+PYRIDOXINE+PYRAZINAMIDE belongs to the group of medicines called anti-tuberculosis drugs primarily used to treat tuberculosis. RIFAMPICIN+ETHAMBUTOL+ISONIAZID+PYRIDOXINE+PYRAZINAMIDE contains Rifampicin, Ethambutol, Isoniazid, Pyridoxine and Pyrazinamide. Rifampicin inactivates the RNA-polymerase enzyme, which is necessary for the bacteria to reproduce and make essential proteins. Pyrazinamide and Ethambutol slow the growth of the bacteria. Isoniazid prevents the formation of bacterial protective covering. Pyridoxine prevents nerve damage that might be caused by Isoniazid. Together, it help treat tuberculosis.
Directions for Use
Storage
Side Effects of RIFAMPICIN+ETHAMBUTOL+ISONIAZID+PYRIDOXINE+PYRAZINAMIDE
- Nausea
- Vomiting
- Stomach pain
- Headache
- Diarrhoea
In-Depth Precautions and Warning
Drug Warnings
Do not take RIFAMPICIN+ETHAMBUTOL+ISONIAZID+PYRIDOXINE+PYRAZINAMIDE if you are allergic to any of its components. Inform the doctor if you have diabetes, epilepsy, gout, mental health problems, HIV infection, malnutrition, peripheral neuropathy, porphyria, bleeding problems, kidney or liver problems. Consult the doctor before taking RIFAMPICIN+ETHAMBUTOL+ISONIAZID+PYRIDOXINE+PYRAZINAMIDE if you are pregnant. Avoid breastfeeding while taking RIFAMPICIN+ETHAMBUTOL+ISONIAZID+PYRIDOXINE+PYRAZINAMIDE as it may pass into breast milk. Let the doctor know if you take other medicines, including herbal products and supplements.
Drug Interactions
Drug-Drug Interactions: Inform the doctor if you are taking an antibiotic (erythromycin), pain killer (acetaminophen), or anti-HIV (saquinavir, ritonavir).
Drug-Food Interactions: Avoid foods and drinks containing histamine or tyramine, such as cured meat, matured cheese, soya, tuna, salmon, mackerel, wine, and beer, while taking RIFAMPICIN+ETHAMBUTOL+ISONIAZID+PYRIDOXINE+PYRAZINAMIDE as they might cause interaction.
Drug-Disease Interactions: Inform the doctor if you have colitis, peripheral neuropathy (numbness and pain in hands and feet), porphyria, diabetes, gout (high uric acid), or kidney or liver dysfunction.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
cautionAvoid alcohol consumption while taking RIFAMPICIN+ETHAMBUTOL+ISONIAZID+PYRIDOXINE+PYRAZINAMIDE as it could lead to unpleasant side effects.
Pregnancy
cautionPlease consult the doctor if you are pregnant; your doctor will prescribe RIFAMPICIN+ETHAMBUTOL+ISONIAZID+PYRIDOXINE+PYRAZINAMIDE only if the benefits outweigh the risks.
Breast Feeding
unsafeRIFAMPICIN+ETHAMBUTOL+ISONIAZID+PYRIDOXINE+PYRAZINAMIDE may pass into breast milk. Do not breastfeed while taking RIFAMPICIN+ETHAMBUTOL+ISONIAZID+PYRIDOXINE+PYRAZINAMIDE.
Driving
cautionRIFAMPICIN+ETHAMBUTOL+ISONIAZID+PYRIDOXINE+PYRAZINAMIDE may cause dizziness, numbness and tingling in hands and feet. Do not drive or operate machinery if you experience these symptoms.
Liver
cautionDose adjustment may be needed. Please consult the doctor if you have liver impairment/liver disease before taking RIFAMPICIN+ETHAMBUTOL+ISONIAZID+PYRIDOXINE+PYRAZINAMIDE.
Kidney
cautionDose adjustment may be needed. Please consult the doctor if you have any concerns regarding this or if you have kidney impairment/kidney disease before taking RIFAMPICIN+ETHAMBUTOL+ISONIAZID+PYRIDOXINE+PYRAZINAMIDE.
Children
unsafeRIFAMPICIN+ETHAMBUTOL+ISONIAZID+PYRIDOXINE+PYRAZINAMIDE is not recommended for use in children.
Habit Forming
Diet & Lifestyle Advise
- Pineapple juice might help soothe the symptoms of cough and cold. It also has anti-inflammatory and mucolytic properties.
- Foods rich in vitamin C, such as kiwi, broccoli, and bell pepper, help improve the immune system.
- Avoid processed and fried foods.
- Warm ginger tea or warm soup can help relieve a cough.
- Avoid foods and drinks containing histamine or tyramine, such as cured meat, matured cheese, soya, tuna, salmon, mackerel, wine, and beer.
- Quit smoking and avoid alcohol consumption.
Patients Concern
Disease/Condition Glossary
Tuberculosis (TB): Tuberculosis is an infectious disease that affects the lungs, but it can also spread to other body parts such as kidneys, brain, spine, and bone marrow. Tuberculosis is caused by a bacteria named Mycobacterium tuberculosis. It is a contagious disease which can spread to others through small droplets released into the air by a person suffering from tuberculosis. Symptoms include a cough that lasts for a few weeks, pain while coughing or with normal breathing, unexplained fatigue, fever, night sweats, loss of appetite and weight. People who smoke or consume alcohol, people diagnosed with HIV, and immune system problems are more likely at risk of developing active TB.
FAQs
RIFAMPICIN+ETHAMBUTOL+ISONIAZID+PYRIDOXINE+PYRAZINAMIDE is used to treat Tuberculosis.
RIFAMPICIN+ETHAMBUTOL+ISONIAZID+PYRIDOXINE+PYRAZINAMIDE works by killing the bacteria named Mycobacterium tuberculosis, which causes TB (tuberculosis).
Do not stop taking RIFAMPICIN+ETHAMBUTOL+ISONIAZID+PYRIDOXINE+PYRAZINAMIDE despite symptomatic relief. To treat your condition effectually, continue taking RIFAMPICIN+ETHAMBUTOL+ISONIAZID+PYRIDOXINE+PYRAZINAMIDE for as long as it has been prescribed for you.
RIFAMPICIN+ETHAMBUTOL+ISONIAZID+PYRIDOXINE+PYRAZINAMIDE might decrease the effectiveness of oral contraceptives (birth control pills). Use a reliable barrier method of contraception such as condoms or the coil while taking RIFAMPICIN+ETHAMBUTOL+ISONIAZID+PYRIDOXINE+PYRAZINAMIDE. Consult your doctor if you have any concerns regarding this; your doctor may suggest an alternate method of contraception.
RIFAMPICIN+ETHAMBUTOL+ISONIAZID+PYRIDOXINE+PYRAZINAMIDE may cause discolouration of teeth, sweat, urine, sputum (phlegm), saliva, or tears. The colour in tears may last for some time, even after you stop taking RIFAMPICIN+ETHAMBUTOL+ISONIAZID+PYRIDOXINE+PYRAZINAMIDE. Do not worry, as it is a common side-effect of RIFAMPICIN+ETHAMBUTOL+ISONIAZID+PYRIDOXINE+PYRAZINAMIDE. Also, RIFAMPICIN+ETHAMBUTOL+ISONIAZID+PYRIDOXINE+PYRAZINAMIDE might permanently stain soft contact lenses. Use spectacles and avoid wearing contact lenses while taking RIFAMPICIN+ETHAMBUTOL+ISONIAZID+PYRIDOXINE+PYRAZINAMIDE.
