Prulifloxacin
About Prulifloxacin
Prulifloxacin belongs to a class of drugs known as 'antibiotics' used in the treatment of bacterial infections. It helps treat infections of the urinary tract, tonsils, sinus, nose, throat, female genital organ, skin and soft tissues, and lungs (pneumonia). A bacterial infection is a condition in which bacteria grow in the body and cause infection. It can target any body part and multiple very quickly. Prulifloxacin does not treat infections caused by virus-like flu or a common cold.
Prulifloxacin contains 'Prulifloxacin' used to treat bacterial infections. The bactericidal action of Prulifloxacin results from interference with the enzyme DNA gyrase which is needed for the synthesis of bacterial DNA (genetic material). Prulifloxacin is efficacious against Gram-negative bacteria. It also has enhanced activity against Gram-positive bacteria, including MRSA and Streptococcus pneumoniae.
Take Prulifloxacin as prescribed by your doctor. You are advised to take Prulifloxacin for as long as your doctor has prescribed it for you, depending upon your medical condition. You may experience vomiting, headache, dizziness, stomach pain, nausea, diarrhoea, and abnormal liver function tests in some cases. However, if the side effects are persistent, reach out to your doctor. If you experience any allergic reaction symptoms such as rashes, itching, swelling, or shortness of breath immediately contact a doctor.
Do not take Prulifloxacin if you are allergic or have had a severe reaction to Prulifloxacin. Taking Prulifloxacin may increase the chances of developing tendinitis or have a tendon rupture. Taking Prulifloxacin may worsen muscle weakness in people with myasthenia gravis (muscle weakness disorder) and cause severe difficulty breathing or death. Dairy products should be avoided along with Prulifloxacin. And also, exposure to sunlight should be avoided while taking Prulifloxacin as it may cause increased phototoxicity or photosensitivity. Do not take Prulifloxacin on your own as self-medication may lead to antibiotic-resistance in which antibiotics fail to act against specific bacterial infections. And also, if prescribed by your doctor Prulifloxacin is safe to use during pregnancy and breastfeeding.
Uses of Prulifloxacin
Medicinal Benefits
Prulifloxacin belongs to the group of medicines called fluoroquinolone antibiotics used to treat bacterial infections, including infections of the urinary tract, tonsils, sinus, nose, throat, sexually transmitted infections, soft tissue infection and lungs (pneumonia). Prulifloxacin contains Prulifloxacin, the prodrug of ulifloxacin, is a broad-spectrum activity with bactericidal action (kills bacteria) that works by preventing synthesis of enzymes, namely DNA gyrase and Topoisomerase IV, which is essential for growth and survival of the bacterial cell. Prulifloxacin has a broad spectrum of antibacterial activity against aerobic gram-positive and aerobic gram-negative bacteria (that live in oxygen). Prulifloxacin does not treat infections caused by virus-like flu or a common cold.
Directions for Use
Storage
Side Effects of Prulifloxacin
- Nausea
- Vomiting
- Stomach pain
- Headache
- Dizziness
- Diarrhea
- Abnormal liver function tests
- Skin rash
Drug Warnings
Prulifloxacin should be avoided if you are pregnant or planning to become pregnant and breastfeeding unless your doctor prescribed it. Taking Prulifloxacin may increase the chances of developing tendinitis (swelling of a fibrous tissue that connects a bone to a muscle) or have a tendon rupture (tearing of a fibrous tissue that connects a bone to a muscle). Inform your doctor if you have or have ever had a kidney or liver disease, heart or lung transplant, seizures (fits), epilepsy or if you participate in regular physical activity. Taking Prulifloxacin may worsen muscle weakness in people with myasthenia gravis (a nervous system disorder that causes muscle weakness) and cause severe difficulty breathing or death. Patients with epilepsy and irregular heartbeat (especially a condition known as QT prolongation) should tell their doctor before taking Prulifloxacin. Dairy products should be avoided along with Prulifloxacin. And also, exposure to sunlight should be avoided while taking Prulifloxacin as it may cause increased phototoxicity or photosensitivity.
Drug Interactions
Drug-Drug Interaction: Prulifloxacin is known to interact with blood thinner (warfarin) antacids containing (calcium, magnesium, aluminium), a medicine used to treat asthma (theophylline), antiulcer (cimetidine) antigout (probenecid), pain killers (ibuprofen, naproxen, aspirin, diclofenac, celecoxib), antidiabetic medicines (chlorpropamide, glimepiride, glipizide, glyburide, tolazamide, tolbutamide), medicine used to treat high blood pressure (nicardipine).
Drug-Food Interaction: Prulifloxacin interacts with alcohol and antacids containing aluminum and magnesium. Also, it is known to interact with dairy products.
Drug-Disease Interaction: Prulifloxacin is known to interact in patients with kidney or liver disease, heart, or lung transplant, seizures, epilepsy, hypertension (high blood pressure), diabetes, myasthenia gravis (a muscle disorder), low level of potassium or magnesium in the blood.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
cautionAlcohol is not known to cause any unpleasant side effects if taken along with Prulifloxacin. But intake of alcohol with Prulifloxacin may damage your liver. So intake of Prulifloxacin should be avoided with Prulifloxacin.
Pregnancy
cautionPrulifloxacin is a pregnancy Category B medicine. It may not cause harm to an unborn foetus. However, Prulifloxacin should be taken only when prescribed by a doctor only if he/she thinks benefits overweigh the risks.
Breast Feeding
cautionBefore taking this drug doctor's consultation is mandatory. It is not known whether Prulifloxacin can pass through the breast milk or not.
Driving
cautionAfter taking this drug, you can experience side effects like feeling dizzy, tired, or alterations in your vision. If this occurs, do not drive or perform any work that requires high level of concentration.
Liver
cautionPrulifloxacin to be taken with caution, especially if you have a history of liver diseases/conditions. Your doctor may have to adjust the dose if there are symptoms of nausea, vomiting, loss of appetite, dark-coloured urine or yellowing of skin/eye.
Kidney
cautionPrulifloxacin to be taken with caution, especially if you have a history of Kidney diseases/conditions. The dose may have to be adjusted by your doctor.
Children
cautionThe safety and efficacy of Prulifloxacin are not studied in children below the age of 18 years. So, it should be only taken by the children if a doctor has prescribed it.
Habit Forming
Diet & Lifestyle Advise
- Probiotics should be taken after taking the full course of Prulifloxacin to restore some healthy bacteria in the intestines that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhea. Certain fermented foods like yogurt, cheese, sauerkraut, kombucha, and kimchi can help restore the intestine's good bacteria.
- Include more fiber-enriched food in your diet, as it can be easily digested by your gut bacteria, which helps stimulate their growth. Thus, fiber-rich foods may help restore healthy gut bacteria after a course of antibiotics. Whole grains like whole-grain bread and brown rice should be included in your diet. Make sure you drink plenty of water or other fluids every day while you are taking Prulifloxacin.
- Avoid alcohol, soda, coffee, tea, and artificial sweeteners as they may cause bladder irritation.
- Drink plenty of water to flush out the bacteria.
- Avoid spicy foods and citrus fruits (lemons, oranges, grapefruits) as they may irritate the bladder.
- Eat foods antioxidant-rich foods such as blueberries, cranberries, tomatoes, spinach, broccoli, and plain greek yogurt.
Special Advise
- During treatment and after 48 hours of discontinuation of treatment with Prulifloxacin, limit exposure to heavy sunlight or artificial UV rays (e.g. sunlight).
- Please consult a doctor if the infection persists or worsens after 1 week of using Prulifloxacin.
- Monitor liver function test (LFT), renal function test, white blood cell count, blood glucose level in diabetic patients as Prulifloxacin may cause harmful interactions in these patients.
- Prulifloxacin can cause dehydration, so please increase the intake of fluids.
- Prulifloxacin is known to cause tendon rupture, so be cautious while taking Prulifloxacin if you have a tendon rupture history.
- Prulifloxacin may cause live bacterial vaccines (such as typhoid vaccine) not to work as well. So, do not have any immunizations/vaccinations while using this medication unless your doctor tells you.
Patients Concern
Disease/Condition Glossary
Bacterial infections: A bacterial infection is a condition in which harmful bacteria enter, multiply, and infect our body. It can target any body part and multiply very quickly. When you get infected with bacteria, you can experience generalized symptoms, like fevers, chills, and fatigue. Bacteria are of various forms comprising commonly of spherical, rod, and spiral-shaped. Bacterial infections vary from minor illnesses like sore throat and ear infections to severe brain infections like meningitis and encephalitis. Anyone can become infected with a bacterial infection. But, people with weak immune systems or taking immunosuppressive medicine are more prone to bacterial infection.
FAQs
Prulifloxacin is used to treat bacterial infections of the urinary tract, tonsils, sinus, nose, throat, female genital organ, skin and soft tissues, and lungs (pneumonia).
Prulifloxacin contains Prulifloxacin, primarily used to treat or prevent certain infections caused by bacteria. The bactericidal (killing) action of Prulifloxacin results from interference with the enzyme DNA gyrase and DNA synthesis process needed to survive the bacteria.
Yes, the use of Prulifloxacin is known to increase the risk of muscle damage, commonly in the ankle. It can happen to people of all ages. Please inform your doctor before taking Prulifloxacin if you have any muscle pain.
Take the missed dose as soon as possible and try not to take a double dose to make up for the missed dose as it may cause harmful effects. It is advised to jump to the next dose if it's been too late to take the missed dose.
It is recommended not to take dairy products such as milk, yoghurt, and Prulifloxacin as they might decrease the effectiveness of Prulifloxacin. Please maintain a gap of at least 2 hours between both of them.
No. Prulifloxacin is an antibacterial medicine that acts only against bacterial infections and not against viral infections, causing cough, cold and flu. You should not take Prulifloxacin without prior consulting your doctor. Self-medication is dangerous and can lower the efficacy of Prulifloxacin, leading to antibiotic resistance.
Prulifloxacin is known to increase the risk of tendinitis and tendon rupture in all ages. But, the elderly are at increase risk of getting it. So, only take Prulifloxacin if prescribed by a doctor in exact dose and duration.
Prulifloxacin may cause diarrhea in some individuals, as it is a commonly reported side effect. However, this effect may subside over time as the medication adjusts to the body. If the diarrhea persists, it is recommended to consult your doctor without hesitation for proper management of the symptoms.
No, you should not stop taking Prulifloxacin even if you feel better without consulting your doctor. It's best to complete the prescribed duration, even if your symptoms vanish. Stopping earlier may lead to the recurrence of the infection and negative effects. Instead, inform your doctor. They will assess your condition, guide you on how to safely stop the medication if necessary.
Yes, the use of Prulifloxacin may increase the risk of muscle damage, especially in people with myasthenia gravis. If you experience any muscle pain, please inform your doctor priorly, before prescribing Prulifloxacin to you.
In some individuals, Prulifloxacin may cause some common side effects such as vomiting, headache, dizziness, stomach pain, nausea, diarrhea, and abnormal liver function tests, allergic reactions. However, this effect may subside over time as the medication adjusts to the body. If these side effects persist, it is recommended to consult your doctor.
