Prulin Tablet

Prulin Tablet belongs to a class of drugs known as 'antibiotics' used in the treatment of bacterial infections. It helps treat infections of the urinary tract, tonsils, sinus, nose, throat, female genital organ, skin and soft tissues, and lungs (pneumonia). A bacterial infection is a condition in which bacteria grow in the body and cause infection. It can target any body part and multiple very quickly. Prulin Tablet does not treat infections caused by virus-like flu or a common cold. 

Prulin Tablet contains 'Prulifloxacin' used to treat bacterial infections. The bactericidal action of Prulin Tablet results from interference with the enzyme DNA gyrase which is needed for the synthesis of bacterial DNA (genetic material). Prulifloxacin is efficacious against Gram-negative bacteria. It also has enhanced activity against Gram-positive bacteria, including MRSA and Streptococcus pneumoniae.

Take Prulin Tablet as prescribed by your doctor. You are advised to take Prulin Tablet for as long as your doctor has prescribed it for you, depending upon your medical condition. You may experience vomiting, headache, dizziness, stomach pain, nausea, diarrhoea, and abnormal liver function tests in some cases. However, if the side effects are persistent, reach out to your doctor. If you experience any allergic reaction symptoms such as rashes, itching, swelling, or shortness of breath immediately contact a doctor. 

Do not take Prulin Tablet if you are allergic or have had a severe reaction to Prulin Tablet. Taking Prulin Tablet may increase the chances of developing tendinitis or have a tendon rupture. Taking Prulin Tablet may worsen muscle weakness in people with myasthenia gravis (muscle weakness disorder) and cause severe difficulty breathing or death. Dairy products should be avoided along with Prulin Tablet. And also, exposure to sunlight should be avoided while taking Prulin Tablet as it may cause increased phototoxicity or photosensitivity.  Do not take Prulin Tablet on your own as self-medication may lead to antibiotic-resistance in which antibiotics fail to act against specific bacterial infections. And also, if prescribed by your doctor Prulin Tablet is safe to use during pregnancy and breastfeeding.

Prulin Tablet belongs to the group of medicines called fluoroquinolone antibiotics used to treat bacterial infections, including infections of the urinary tract, tonsils, sinus, nose, throat, sexually transmitted infections, soft tissue infection and lungs (pneumonia). Prulin Tablet contains Prulifloxacin, the prodrug of ulifloxacin, is a broad-spectrum activity with bactericidal action (kills bacteria) that works by preventing synthesis of enzymes, namely DNA gyrase and Topoisomerase IV, which is essential for growth and survival of the bacterial cell. Prulin Tablet has a broad spectrum of antibacterial activity against aerobic gram-positive and aerobic gram-negative bacteria (that live in oxygen). Prulin Tablet does not treat infections caused by virus-like flu or a common cold.

• Nausea
• Vomiting
• Stomach pain
• Headache
• Dizziness
• Diarrhea
• Abnormal liver function tests
• Skin rash

Prulin Tablet should be avoided if you are pregnant or planning to become pregnant and breastfeeding unless your doctor prescribed it. Taking Prulin Tablet may increase the chances of developing tendinitis (swelling of a fibrous tissue that connects a bone to a muscle) or have a tendon rupture (tearing of a fibrous tissue that connects a bone to a muscle). Inform your doctor if you have or have ever had a kidney or liver disease, heart or lung transplant, seizures (fits), epilepsy or if you participate in regular physical activity. Taking Prulin Tablet may worsen muscle weakness in people with myasthenia gravis (a nervous system disorder that causes muscle weakness) and cause severe difficulty breathing or death. Patients with epilepsy and irregular heartbeat (especially a condition known as QT prolongation) should tell their doctor before taking Prulin Tablet. Dairy products should be avoided along with Prulin Tablet. And also, exposure to sunlight should be avoided while taking Prulin Tablet as it may cause increased phototoxicity or photosensitivity.

Drug-Drug Interaction: Prulin Tablet is known to interact with blood thinner (warfarin) antacids containing (calcium, magnesium, aluminium), a medicine used to treat asthma (theophylline), antiulcer (cimetidine) antigout (probenecid), pain killers (ibuprofen, naproxen, aspirin, diclofenac, celecoxib), antidiabetic medicines (chlorpropamide, glimepiride, glipizide, glyburide, tolazamide, tolbutamide), medicine used to treat high blood pressure (nicardipine).

Drug-Food Interaction:  Prulin Tablet interacts with alcohol and antacids containing aluminum and magnesium. Also, it is known to interact with dairy products.

Drug-Disease Interaction: Prulin Tablet is known to interact in patients with kidney or liver disease, heart, or lung transplant, seizures, epilepsy, hypertension (high blood pressure), diabetes, myasthenia gravis (a muscle disorder),  low level of potassium or magnesium in the blood.

• WARFARIN
• CALCIUM
• MAGNESIUM HYDROXIDE
• ALUMINIUM HYDROXIDE
• THEOPHYLLINE
• CIMETIDINE
• PROBENECID
• IBUPROFEN
• NAPROXEN
• ASPIRIN
• DICLOFENAC
• CELECOXIB
• CHLORPROPAMIDE
• GLIMEPIRIDE
• GLIPIZIDE
• GLYBURIDE
• TOLAZAMIDE
• TOLBUTAMIDE
• NICARDIPINE

• Probiotics should be taken after taking the full course of Prulin Tablet to restore some healthy bacteria in the intestines that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhea. Certain fermented foods like yogurt, cheese, sauerkraut, kombucha, and kimchi can help restore the intestine's good bacteria. 
• Include more fiber-enriched food in your diet, as it can be easily digested by your gut bacteria, which helps stimulate their growth. Thus, fiber-rich foods may help restore healthy gut bacteria after a course of antibiotics. Whole grains like whole-grain bread and brown rice should be included in your diet. Make sure you drink plenty of water or other fluids every day while you are taking Prulin Tablet.
• Avoid alcohol, soda, coffee, tea, and artificial sweeteners as they may cause bladder irritation. 
• Drink plenty of water to flush out the bacteria.
• Avoid spicy foods and citrus fruits (lemons, oranges, grapefruits) as they may irritate the bladder. 
• Eat foods antioxidant-rich foods such as blueberries, cranberries, tomatoes, spinach, broccoli, and plain greek yogurt.

• During treatment and after 48 hours of discontinuation of treatment with Prulin Tablet, limit exposure to heavy sunlight or artificial UV rays (e.g. sunlight).
• Please consult a doctor if the infection persists or worsens after 1 week of using Prulin Tablet.
• Monitor liver function test (LFT), renal function test, white blood cell count, blood glucose level in diabetic patients as Prulin Tablet may cause harmful interactions in these patients.
• Prulin Tablet can cause dehydration, so please increase the intake of fluids.
• Prulin Tablet is known to cause tendon rupture, so be cautious while taking Prulin Tablet if you have a tendon rupture history.
• Prulin Tablet may cause live bacterial vaccines (such as typhoid vaccine) not to work as well. So, do not have any immunizations/vaccinations while using this medication unless your doctor tells you.

Bacterial infections: A bacterial infection is a condition in which harmful bacteria enter, multiply, and infect our body. It can target any body part and multiply very quickly. When you get infected with bacteria, you can experience generalized symptoms, like fevers, chills, and fatigue. Bacteria are of various forms comprising commonly of spherical, rod, and spiral-shaped. Bacterial infections vary from minor illnesses like sore throat and ear infections to severe brain infections like meningitis and encephalitis. Anyone can become infected with a bacterial infection. But, people with weak immune systems or taking immunosuppressive medicine are more prone to bacterial infection.