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TOLPERISONE+PARACETAMOL

About

PARACETAMOL+TOLPERISONE is used to treat muscle spasms. It improves the movement of muscles and provides relief from pain and discomfort caused by the muscle spasm. A muscle spasm occurs due to involuntary contractions of a muscle. A spasm may be a twitch in the muscle or may feel tight or hard, like a knot.

PARACETAMOL+TOLPERISONE is a combination of two drugs: Tolperisone (muscle relaxant) and Paracetamol (pain killer). Tolperisone works on the spinal cord and brain to relieve contraction or muscle stiffness. It also increases the supply of blood to the muscles. Paracetamol is an analgesic (pain reliever) and an antipyretic (fever reducer). It inhibits cyclo-oxygenase (COX) enzymes that further prevent the formation of chemical messengers called 'prostaglandins' (PGs). These prostaglandins are produced at injury sites and cause pain and swelling. By blocking the COX enzyme's effect, lesser PGs are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site.

Your doctor will decide the dose and duration based on the severity of your pain. Common side effects of PARACETAMOL+TOLPERISONE include nausea, vomiting, dry mouth, dizziness, weakness and sleepiness. These side effects are not familiar to everyone and vary individually.

Let your doctor know if you use any prescription and non-prescription medications before starting PARACETAMOL+TOLPERISONE. Inform your doctor if you have any liver, heart or kidney diseases, myasthenia gravis (fatigue of muscles) and phenylketonuria (a genetic disorder that causes an amino acid build-up, phenylalanine) and alcohol dependency. Consult your doctor before taking PARACETAMOL+TOLPERISONE if you are pregnant or planning for pregnancy. PARACETAMOL+TOLPERISONE may cause dizziness, so drive only if you are alert and focused. PARACETAMOL+TOLPERISONE should not be given to children as safety has not been established. Avoid consuming alcohol and PARACETAMOL+TOLPERISONE as it could lead to increased dizziness and risk of liver damage.

Uses of TOLPERISONE+PARACETAMOL

Treatment of Muscle spasms.

Medicinal Benefits

PARACETAMOL+TOLPERISONE treats muscle spasms and consists of Tolperisone (muscle relaxant) and Paracetamol (pain killer). Tolperisone is a centrally-acting muscle relaxant. It works on the spinal cord and brain to relieve contraction or muscle stiffness. It also increases the supply of blood to the muscles. Paracetamol is an analgesic (pain reliever) and an antipyretic (fever reducer). It inhibits cyclo-oxygenase (COX) enzymes that further prevent the formation of chemical messengers called 'prostaglandins' (PGs). These prostaglandins are produced at injury sites and cause pain and swelling. By blocking the COX enzyme's effect, fewer PGs are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site.

Directions for Use

Swallow the medicine as a whole with a glass of water; do not chew or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of TOLPERISONE+PARACETAMOL

  • Nausea
  • Vomiting
  • Dry mouth
  • Dizziness
  • Weakness
  • Sleepiness

In-Depth Precautions and Warning

Drug Warnings

Inform your doctor if you have any liver, heart or kidney diseases, myasthenia gravis (fatigue of muscles), phenylketonuria (a genetic disorder that causes a build-up of an amino acid, phenylalanine), and alcohol dependency before starting PARACETAMOL+TOLPERISONE. Consult your doctor before taking PARACETAMOL+TOLPERISONE if you are pregnant, planning for pregnancy or breastfeeding. PARACETAMOL+TOLPERISONE may cause dizziness, so drive only if you are alert and focused. Avoid consuming alcohol along with PARACETAMOL+TOLPERISONE as it could lead to increased dizziness and risk of liver damage. PARACETAMOL+TOLPERISONE is not recommended in children as safety and efficacy is not established.

Drug Interactions

Drug-Drug Interactions: PARACETAMOL+TOLPERISONE may interact with anticoagulants (warfarin), drugs treating vomiting (metoclopramide, domperidone), cholesterol-lowering medications (cholestyramine) and anti-cancer medications (imatinib).

Drug-Food Interactions: Alcohol consumption may cause dizziness and increases the risk of liver damage.

Drug-Disease Interactions: Before using PARACETAMOL+TOLPERISONE, let your doctor know if you have any liver, heart or kidney diseases, myasthenia gravis (fatigue of muscles), phenylketonuria (a genetic disorder that causes a build-up of an amino acid, phenylalanine), and alcohol dependency.

Drug-Drug Interactions Checker List:

  • WARFARIN
  • METOCLOPRAMIDE
  • DOMPERIDONE
  • CHOLESTYRAMINE
  • IMATINIB
  • Safety Advice

    • Safety Warning

      Alcohol

      unsafe

      You are recommended to avoid alcohol consumption while taking PARACETAMOL+TOLPERISONE. Alcohol intake, along with PARACETAMOL+TOLPERISONE, may cause increased dizziness and risk of liver damage.

    • Safety Warning

      Pregnancy

      caution

      PARACETAMOL+TOLPERISONE should be used with caution during pregnancy. Please consult your doctor before taking PARACETAMOL+TOLPERISONE.

    • Safety Warning

      Breast Feeding

      caution

      PARACETAMOL+TOLPERISONE should be used with caution during breastfeeding. Please consult your doctor before taking PARACETAMOL+TOLPERISONE.

    • Safety Warning

      Driving

      caution

      PARACETAMOL+TOLPERISONE may make you feel dizzy. Do not drive or operate machinery if you experience dizziness.

    • Safety Warning

      Liver

      caution

      Please consult your doctor since PARACETAMOL+TOLPERISONE should be used with caution in patients with liver impairment/liver disease.

    • Safety Warning

      Kidney

      caution

      Please consult your doctor since PARACETAMOL+TOLPERISONE should be used with caution in patients with kidney impairment/kidney disease.

    • Safety Warning

      Children

      unsafe

      PARACETAMOL+TOLPERISONE is not recommended in children as safety and efficacy is not established.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Exercising regularly helps in muscle stretching that is less likely to spasm, tear and sprain. Mild exercises such as jogging and walking are helpful for muscle stretching.
    • Massages can also be helpful.
    • Avoid freezing and hot temperatures.
    • Avoid wearing tight-fitting clothes, instead, wear loose garments.
    • Rest well and get plenty of sleep.
    • To avoid developing pressure sores, change your position at least every two hours.
    • Hot or cold therapy can haelp treat muscle spasms. Apply an ice-pack or hot-pack on the muscle for 15-20minutes.
    • Stay hydrated, drink plenty of water.

    Special Advise

    • Let your doctor know that you are taking PARACETAMOL+TOLPERISONE if you are undergoing any medical tests.
    • PARACETAMOL+TOLPERISONE may cause fluid retention (oedema), hence it is advised to monitor blood pressure and cardiovascular status in patients with a heart failure history.
    • Explain a detail history to the doctor as use of PARACETAMOL+TOLPERISONE is contraindicated in patients with myasthenia gravis.

    Patients Concern

    Disease/Condition Glossary

    Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body.

    Muscle spasm is the sudden involuntary contractions of the muscle, which can be painful and uncomfortable. When the nerve impulses that control the muscle movements are damaged or interrupted, it could lead to muscle spasms. A spasm may be a twitch in the muscle or may feel tight or hard, like a knot.

    FAQs

    PARACETAMOL+TOLPERISONE is used to treat muscle spasms. It improves the movement of muscles and provides relief from pain and discomfort caused by the muscle spasm.

    PARACETAMOL+TOLPERISONE is a combination of two drugs: Tolperisone and Paracetamol. Tolperisone works on the spinal cord and brain to relieve contraction or muscle stiffness. Paracetamol works by blocking the action of certain chemical messengers that cause pain.

    PARACETAMOL+TOLPERISONE is usually used for a short period and can be discontinued if there is no pain. However, it should be continued if advised by the doctor.

    PARACETAMOL+TOLPERISONE is to be carefully administered in patients with alcohol dependency, kidney or liver damage, myasthenia gravis (fatigue of muscles) and phenylketonuria (a genetic disorder that causes the build-up of an amino acid, phenylalanine). Please consult your doctor before starting PARACETAMOL+TOLPERISONE if you have a medical history.

    PARACETAMOL+TOLPERISONE may cause stomach upset; hence taking it with food will prevent you from getting an upset stomach.

    Available Medicines for

    TOLPERISONE+PARACETAMOL

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