Naproxen+pantoprazole
About Naproxen+pantoprazole
Naproxen+pantoprazole belongs to a group of medicines called Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) or pain killers used to reduce and relieve pain, redness and inflammation (swelling) in patients suffering from osteoarthritis, rheumatoid arthritis and ankylosing spondylitis, cervical spondylitis (wear and tear of spinal discs in neck), dysmenorrhea, mild migraine and acute gout (severe pain due to an excess of uric acid) in adult and children. Rheumatoid arthritis is an autoimmune disease in which the immune system of the body attacks its cells and causes damage, thereby causing joint pain with inflammation.
Naproxen+pantoprazole is a combination of two drugs: Naproxen (painkiller) and Pantoprazole (antacid). Naproxen is an anti-inflammatory drug that works by blocking the action of the cyclo-oxygenase (COX) enzyme in the body that is involved in the production of certain chemical substances (prostaglandins) that cause pain and swelling. This helps in reducing mild to moderate pain and inflammation at the injured or damaged site decreasing stiffness in joints. It is also used to treat low back pain, strains, and sprains. Naproxen has been reported to cause gastric discomfort, acidity, and risk of stomach ulcers. Hence, it is combined with Pantoprazole (proton pump inhibitors) which reduces the amount of acid made by the stomach, thus preventing damage to the stomach. Thus, the combination helps alleviate pain with minimal gastric irritation caused due to Naproxen alone.
Take Naproxen+pantoprazole as prescribed by your doctor. You are advised to take Naproxen+pantoprazole for as long as your doctor has prescribed it for you based on your medical condition. You may experience indigestion, stomach pain, constipation, dizziness, nausea, and diarrhea in some cases. Most of these side effects of Naproxen+pantoprazole do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
Before taking this medicine, inform your doctor if you have any known allergy to naproxen, pantoprazole, other NSAIDs or other medications. If you are pregnant or breastfeeding, please inform your doctor before taking Naproxen+pantoprazole. Also, inform the doctor if you have a history of heart rhythm problems or ulcers due to painkillers. Patients with age above 65 years, with pre-existing cardiac diseases such as heart failure, hypertension or stroke, gastrointestinal bleeding (due to pain killers), gastric ulcers, respiratory diseases such as asthma, liver diseases, kidney diseases, or bleeding disorders should use Naproxen+pantoprazole only when prescribed by a doctor.
Uses of Naproxen+pantoprazole
Medicinal Benefits
Naproxen+pantoprazole is a combination of two drugs, namely: Naproxen is an anti-inflammatory (reduces inflammation) and an analgesic (reduces pain) agent, and Pantoprazole (antacid). Naproxen works by blocking the action of the cyclo-oxygenase (COX) enzyme in the body that is involved in the production of certain chemical substances (prostaglandins) that cause pain and swelling. This helps in reducing mild to moderate pain and inflammation at the injured or damaged site decreasing stiffness in joints. It is also used to treat fibrositis (muscle pain and stiffness), tenosynovitis (swelling of tendons), low back pain, strains and sprains. NSAIDs such as Naproxen have been reported to cause gastric discomfort, acidity, and risk of stomach ulcers. To reduce gastric discomfort and stomach ulceration risk, it is combined with Pantoprazole (a proton pump inhibitor that inhibits gastric acid secretion) to reduce stomach acid production during long-term treatment for people with pre-existing stomach ulcers or for people having a history of developing stomach ulcers while using NSAIDs. Thus, the combination helps alleviate pain with minimal gastric irritation caused due to Naproxen alone.
Directions for Use
Storage
Side Effects of Naproxen+pantoprazole
- Indigestion
- Stomach pain
- Constipation
- Dizziness
- Nausea
- Vomiting
- Kidney dysfunction
- Diarrhoea
Drug Warnings
Do not take Naproxen+pantoprazole if you are allergic to Naproxen+pantoprazole. Long-term use of nonsteroidal anti-inflammatory drugs (NSAIDs) (other than aspirin) such as naproxen may increase the risk of heart attack or stroke and stomach ulcers. The risk of developing ulcers is higher if you have a history of ulcers, have bleeding disorders, older in age, alcoholic or have multiple diseases. Elderly patients are at greater risk for gastrointestinal bleeding problems so the doctor can limit their dose. It should not be used by a patient who has undergone recent heart bypass surgery or going to have it. Naproxen+pantoprazole is not recommended for pregnant women especially in the third trimester as it may cause harm to the baby. Therefore, pregnant or breastfeeding women are advised to consult a doctor before taking Naproxen+pantoprazole. Consult your doctor before giving Naproxen+pantoprazole to children. Do not take any other NSAIDs for pain relief along with Naproxen+pantoprazole unless prescribed. Prolonged intake of PPIs or proton pump inhibitors like pantoprazole may cause brittle bones so intake of Vitamin D and calcium can be additionally given by your doctor while using Naproxen+pantoprazole. Do not consume alcohol with Naproxen+pantoprazole as it may increase the risk of stomach bleeding or ulcer.
Drug Interactions
Drug-Drug Interactions: Naproxen+pantoprazole may have interaction with pain killers (ibuprofen, diclofenac, paracetamol, aspirin), high blood pressure-lowering medicines (propranolol, enalapril, cilazapril, losartan, candesartan, eprosartan), water pills (furosemide), blood thinners (heparin, warfarin, clopidogrel), fits related medicines (phenytoin), antidiabetic drugs (glimepiride, glipizide), antibiotics (moxifloxacin, ciprofloxacin, ampicillin, rifampicin), HIV/AIDS medicines (zidovudine, atazanavir, nelfinavir), antifungal (ketoconazole, voriconazole, itraconazole, posaconazole), heart medicine (digoxin) and anti-cancer drug (methotrexate).
Drug-Food Interactions: Naproxen+pantoprazole may interact with alcohol. Therefore, avoid alcohol intake while taking Naproxen+pantoprazole as it may increase the risk of stomach bleeding and drowsiness, and dizziness.
Drug-Disease Interactions: People with diabetes, stomach ulcer, gastrointestinal bleeding, asthma, kidney, liver, or heart problems, and an autoimmune condition, such as systemic lupus erythematosus (joint pain, fever, and skin rashes), colitis or Crohn’s disease (conditions causing swelling of the bowel, diarrhoea, bowel pain, vomiting, and weight loss) should consult a doctor before taking Naproxen+pantoprazole.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
unsafeYou are recommended to avoid consumption of alcohol with Naproxen+pantoprazole as it may increase the risk of stomach bleeding and ulcer.
Pregnancy
unsafeNaproxen+pantoprazole is a Category C pregnancy drug and is considered unsafe for pregnant women especially in the third trimester. However, please consult your doctor if you are pregnant.
Breast Feeding
cautionNaproxen+pantoprazole passes into the breast milk. However, no evidence of risk has been reported. Please consult your doctor before intake of Naproxen+pantoprazole. Your doctor will weigh the benefits and any potential risks before prescribing it to you.
Driving
cautionNaproxen+pantoprazole may cause dizziness, tiredness, drowsiness or vision problems in some people. So, drive only if you are alert after taking Naproxen+pantoprazole.
Liver
cautionNaproxen+pantoprazole should be used with caution in people having liver diseases. Dose adjustments may be necessary. So, it should be used only with your doctor's prescription.
Kidney
cautionNaproxen+pantoprazole is not recommended for use in patients with moderate to severe and severe renal impairment. The dose may be adjusted by your doctor as required. So, it should be used only when prescribed by your doctor.
Children
unsafeNaproxen+pantoprazole can be used safely in children if prescribed by a doctor.
Habit Forming
Diet & Lifestyle Advise
- Physical activity helps in strengthening muscles and relieves joint stiffness. Gentle activities like 20-30minutes of walking or swimming would be helpful.
- Performing yoga may also help in improving joint flexibility and pain management.
- Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
- Get adequate sleep as resting the muscles can help in reducing inflammation and swelling.
- Follow heat or cold therapy, and apply a cold or hot compress on the joints for 15-20minutes regularly.
- Acupuncture, massage, and physical therapy may also be helpful.
- Foods containing flavonoids such as soy, berries, broccoli, grapes, and green tea help in reducing inflammation.
- Include high-fiber-containing foods, berries, cherries, leafy green veggies, and black peppers in your meal. These foods are full of antioxidants, calcium, and vitamin B12 that can help cope with the long-term effects of the medicine. Fermented dairy products like miso, sauerkraut, and kimchi contain probiotics which help in the prevention of excess stomach acid production.
- Avoid intake of acid or heartburn-triggering foods or drinks like onions, peppermint, chocolate, caffeinated beverages, citrus fruits or juices, tomatoes, and high-fat and spicy foods.
- Avoid smoking and alcohol consumption.
Special Advise
- If you are elderly, a smoker, had stroke previously, or have high blood pressure, diabetes, or high cholesterol, please inform your doctor as these conditions may increase the risk of heart problems.
- Your doctor may monitor liver function and kidney function if you are taking Naproxen+pantoprazole for long-term.
- Individuals at risk for osteoporosis-related fractures should receive an adequate intake of calcium and vitamin D.
- Pantoprazole in Naproxen+pantoprazole may interfere with certain laboratory tests (including urine test for tetrahydrocannabinol-THC, and a blood test to find certain tumors), possibly causing false test results. Make sure laboratory personnel and all your doctors know you are using Naproxen+pantoprazole.
- Regular monitoring of vitamin B-12, rarely, Pantoprazole in Naproxen+pantoprazole have caused vitamin B-12 deficiency. The risk is increased if they are taken Naproxen+pantoprazole every day for a long time.
Patients Concern
Disease/Condition Glossary
Osteoarthritis: It is a degenerative joint disease in which the two ends of the joints come together due to breakdown of a protective covering of cartilage. Due to the absence of this protective covering, the joints rub against each other, leading to pain and stiffness. Symptoms of osteoarthritis include pain, stiffness, inflammation and tenderness. The main reason for osteoarthritis is age, the older you are, the more likely you could get osteoarthritis, thus known as degenerative disease, meaning that the joints wear out as a person ages. Other reasons include a past injuries such as torn cartilage, dislocated joints, and ligament injuries.
Rheumatoid arthritis: It is an auto-immune disease (the body's immune system attacks its tissue) that leads to joint pain and damage. Symptoms of rheumatoid arthritis include pain, swelling, stiffness, deformities, and loss of joint function.
Ankylosing spondylitis: It causes pain and stiffness in the spine. The pain usually starts in the lower back and can spread to the neck, damaged joints, or other parts of the body. Symptoms of ankylosing spondylitis include decreased flexibility which usually leads to a hunched-forward posture, pain, and back and joints.
Migraine: A headache of varying intensity, often accompanied by nausea and sensitivity to light and sound.
Gout: A form of arthritis characterized by severe pain, redness, and tenderness in joints. Pain and inflammation occur when too much uric acid crystallizes and deposits in the joints.
FAQs
Naproxen+pantoprazole is used to relieve pain and inflammation (swelling) in patients suffering from osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, cervical spondylitis, dysmenorrhea, mild migraine and acute gout.
Naproxen+pantoprazole contains Naproxen (non-steroidal anti-inflammatory drug or pain reliever) and Pantoprazole (antacid). Naproxen works by blocking the release of certain chemical messengers (prostaglandins) that cause pain and inflammation (redness and swelling). Pantoprazole works by blocking the action of the enzyme known as the gastric proton pump that is responsible for the production of acid. This helps in reducing the amount of acid produced, heals the ulcers and prevents the formation of new ulcers.
No, you are not recommended to take Naproxen+pantoprazole with clopidogrel as co-administration of these two medicines may increase the risk of bleeding more easily. However, if you notice blood in urine or stools, dizziness, unusual bleeding or bruising, vomiting, weakness or headache, please consult a doctor immediately. If you are supposed to use these medicines together, you are advised to contact your doctor so that the dose may be adjusted appropriately to use safely.
Yes. Naproxen+pantoprazole can alter certain medical tests like neuroendocrine tumours (secretin stimulation test) and urine screening tests for tetrahydrocannabinol (THC). So before undergoing such a diagnostics test contact your doctor.
Yes, Naproxen in Naproxen+pantoprazole may increase the risk of heart problems such as heart attack and stroke especially when used in high doses or for a prolonged duration. It is advised to inform your doctor if you have any of these conditions or have a history of heart problems or stroke before taking Naproxen+pantoprazole. However, it is recommended to take Naproxen+pantoprazole in dose and for the duration as prescribed by your doctor. It should be not used by the patient who have had recent heart bypass surgery (coronary artery bypass graft - CABG).
Arthritis is a chronic condition of joints with pain and inflammation. Naproxen+pantoprazole does not cure arthritis but relieve symptoms of arthritis-like joint pain, swelling and stiffness.
Naproxen+pantoprazole is a pregnancy Category C medicine so, it is advisable to tell your doctor before its intake. It may inhibit ovulation (release of egg from ovary) and decrease the levels of progesterone leading to infertility in women. However, this effect is temporary and ovulation returns to normal mostly after one month of stopping Naproxen+pantoprazole. However, if you are planning for pregnancy or have difficulties becoming pregnant, please inform your doctor before taking Naproxen+pantoprazole.
Yes, Naproxen+pantoprazole is a pain reliever that reduces inflammation and pain. It is commonly used for arthritis, menstrual cramps, and other painful conditions.
Naproxen+pantoprazole can help relieve sinus infection symptoms like pain and inflammation, but it would not fight against the infection. Consult your doctor for appropriate treatment for your sinus infection.
Naproxen+pantoprazole can increase blood pressure in some individuals, especially in those with pre-existing hypertension. Monitor your blood pressure regularly and consult your doctor if any concerns arise.
Naproxen+pantoprazole may cause constipation in some individuals as it is a reported side effect of Naproxen+pantoprazole. However, this symptom vanishes as your body adjusts to the medication. If it worsens, please consult a doctor for relief.
No, Naproxen+pantoprazole does not contain sulfa. It is a combination of naproxen, a nonsteroidal anti-inflammatory, and pantoprazole, a proton pump inhibitor (PPI).
No, Naproxen+pantoprazole is not a controlled substance as it does not have a high potential for abuse or addiction or habit forming.
No, Naproxen+pantoprazole is not an addictive or habit-forming medication.
Naproxen+pantoprazole is generally safe when used as prescribed by a doctor. However, like all medications, it can have side effects and potential interactions with other drugs. It is important to follow your doctor's instructions and inform them about any pre-existing and existing medical conditions or ongoing medications intake to avoid negative complications.
No, Naproxen+pantoprazole is not a narcotic. It's a nonsteroidal anti-inflammatory drug (NSAID) used to relieve pain, inflammation and stomach issues.
Please consult a doctor if you are pregnant or planning for pregnancy. Naproxen+pantoprazole can be given to pregnant women under caution only if the doctor thinks the benefits outweigh the risks.
No, Naproxen+pantoprazole is not a blood thinner. Both naproxen and pantoprazole in its composition does not have any blood thinning properties. But naproxen may increase bleeding risk, but it doesn't thin blood like anticoagulants do. Consult a doctor for appropriate guidance.
Naproxen+pantoprazole can help relieve headache by reducing inflammation and pain. But, consult your doctor for proper diagnosis and treatment.
No, Naproxen+pantoprazole is not available over the counter (OTC) and it requires a prescription from a doctor.
No, do not take Naproxen+pantoprazole with oxycodone without consulting a doctor. Potential interactions may take place and lead to an increase in the risk of negative effects (like bleeding, stomach ulcers, or respiratory depression). Consult a doctor before taking the medication and they will advise you of safe usage.
No, you are not recommended to take Naproxen+pantoprazole with prednisone. This combination may increase the risk of gastrointestinal side effects, such as bleeding, ulcers, and inflammation. It is important to consult your doctor before combining any medications to ensure safety.
Yes, Naproxen+pantoprazole under doctor's guidance for painful period cramps. Usually, it helps to treat dysmenorrhea (menstrual cramps) by reducing pain and inflammation.
Generally, Naproxen+pantoprazole is not used to treat fever. But, it can reduce the fever which is caused due to the pain and inflammation. However, always consult your doctor for proper diagnosis and treatment.
Naproxen+pantoprazole can help to relieve back pain caused by inflammation. However, take it under the doctor's guidance after proper diagnosis.
No, Naproxen+pantoprazole is not typically used to treat cold. It is a combination of naproxen, an anti-inflammatory, and pantoprazole, a proton pump inhibitor, mainly used to relieve pain and inflammation. Consult your doctor for appropriate treatment for a cold.
Naproxen+pantoprazole can relieve headaches and body aches from hangovers, but it is not specifically prescribed for hangover treatment. For relief, try drinking water, resting and eating a balanced meal. Consult your doctor if symptoms persist.
No, Naproxen+pantoprazole is not used to treat gallbladder pain. You should consult a doctor if you have gallbladder pain for proper diagnosis and treatment. They may recommend medications or surgery depending on the underlying cause.
No, Naproxen+pantoprazole can helps in providing relief from tonsillitis symptoms like pain, inflammation, and fever. But it does not cure your tonsillitis. However, consult your doctor for proper diagnosis and treatment suitable to your condition.
No, Naproxen+pantoprazole may provide relief for UTI symptoms like pain and inflammation only, but it won't treat the underlying infection and does not provide a cure for UTI. Consult your doctor for proper treatment.
Naproxen+pantoprazole can provide short-term relief from toothache pain. However, it is necessary to consult your dentist for proper diagnosis and treatment to address the underlying cause.
Yes, Naproxen+pantoprazole can cause sleepy or drowsiness in some people. But, it vanishes over time as the body adjusts to the medication. If you experience drowsiness, it is important to avoid driving or operating heavy machinery and have some rest after taking it. If this symptom gets worse, please consult a doctor for relief.
Naproxen+pantoprazole typically starts working within an hour to relieve pain and inflammation. However, the full effect may take a little longer depending upon individual health conditions.
Yes, like all medications Naproxen+pantoprazole can also expire. Check the packaging for the expiration date. Make sure not to take expired medication.
No, Naproxen+pantoprazole does not contain aspirin. It consists naproxen, a nonsteroidal anti-inflammatory drug (NSAID), and pantoprazole, a proton pump inhibitor (PPI).
No, Naproxen+pantoprazole does not produce a high. Because it contains naproxen and pantoprazole. Neither of these components does not have psychoactive properties or cause euphoria.
Yes, Naproxen+pantoprazole effectively treats pain and inflammation while protecting the stomach. It is generally prescribed for conditions like osteoarthritis, rheumatoid arthritis, tendinitis, gout, and menstrual cramps.
No, Naproxen+pantoprazole can help to relieve flu symptoms like fever, headache, and body aches, but it won't treat the underlying viral infection. Consult your doctor for proper diagnosis and treatment for your flu.
No, do not take Naproxen+pantoprazole without consulting your doctor, as Naproxen+pantoprazole may help to reduce pain and inflammation from swollen glands, but your doctor determines the underlying cause for swollen legs and provides you the suitable treatment.
The common side effects of Naproxen+pantoprazole which may be experienced in some individuals are indigestion, stomach pain, constipation, dizziness, nausea, and diarrhoea in some cases. Most of these side effects of Naproxen+pantoprazole do not require medical attention and gradually resolve over time. However, if these side effects persist or worsen, please consult your doctor.
