Clindamycin+nicotinamide
About Clindamycin+nicotinamide
Clindamycin+nicotinamide belongs to the class of antibiotics known as lincomycin antibiotics, primarily used to treat inflamed acne. It minimizes the formation of excessive natural oil, known as sebum. It also reduces swelling caused due to acne. Acne is a skin-related problem in which oil glands (sebaceous glands) of the skin become clogged, thereby forming pimples and sometimes cysts.
Clindamycin+nicotinamide is composed of two medicines namely: Clindamycin and Nicotinamide. Clindamycin is a lincomycin antibiotic that penetrates the skin and helps kill acne-causing bacteria. On the other hand, Nicotinamide is a form of vitamin B which is responsible for exerting anti-inflammatory effects that are applied to the skin. Together, they help to reduce the swelling, redness and tenderness caused by acne or pimples. Besides this, it also prevents the formation of pimples, blackheads and whiteheads on the skin.
Clindamycin+nicotinamide meant for external use only. It should be applied in sufficient quantity enough to cover the affected area. Wash your hands before and after using this medicine. If accidentally it comes in contact with your eyes, nose, mouth or any other sensitive areas, immediately rinse it with water. In some cases, you may experience irritation, dryness, peeling, redness and burning sensation at the application site. Most of these side effects of Clindamycin+nicotinamide do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor. It is advised to use a skin moisturizer and drink plenty of water to prevent side effects.
Do not stop using this medicine without consulting your doctor. Inform your doctor if you are pregnant or breastfeeding. Also, if you are allergic to this medicine, please tell your doctor. Avoid touching, picking or scratching the infected area to avoid worsening of the acne. It is advised to avoid unnecessary sun exposure and before stepping out in the sun, use sunscreen. Do not use any kind of cosmetic products or get any cosmetic procedures done in the affected area without consulting your doctor.
Uses of Clindamycin+nicotinamide
Medicinal Benefits
Clindamycin+nicotinamide contains Clindamycin and Nicotinamide (Vitamin B3). Clindamycin is a well-known bacteriostatic antibiotic that treats acne, bacterial infection, and scars and is suitable for both dry and wet skin. It helps in the healing of acne by killing the acne-causing bacteria and prevents further bacterial skin infections. Nicotinamide is a synthetic form of Vitamin B3 that stimulates ceramide (fats found on the uppermost layer of the skin) synthesis and improves the epidermal permeability barrier functions, making skin look supple and soft.
Directions for Use
Storage
Side Effects of Clindamycin+nicotinamide
- Irritation
- Dryness
- Peeling
- Redness
- Burning sensation at the application site
Drug Warnings
Clindamycin+nicotinamide is meant for topical use only and not for oral, ophthalmic or intravaginal use. You should not use a Clindamycin+nicotinamide if your skin is very sensitive or allergic to Clindamycin+nicotinamide or lincomycin class antibiotic. Do not apply Clindamycin+nicotinamide on the cut, scraped, sunburned or eczema-affected skin part. If accidentally Clindamycin+nicotinamide gets into your eyes, immediately rinse your eyes with water thoroughly and contact your doctor immediately if the irritation persists. Inform your doctor if your skin conditions do not improve. $ It may take time to treat acne, so do not apply a dosage more than prescribed for better and faster results. If you are pregnant, planning for pregnancy or a nursing mother, consult your doctor before using Clindamycin+nicotinamide. Consult the doctor if you are using dermatological products other than Clindamycin+nicotinamide, as it may lead to unfavourable results like excessive drying of the skin, peeling, irritation, etc.
Drug Interactions
Drug-Drug Interaction: This medicine may have an interaction with antibiotics (clarithromycin, rifampin, erythromycin), anti-HIV drug (indinavir, nelfinavir, ritonavir), antifungals (itraconazole, ketoconazole) and antidepressant (nefazodone). Besides this, Clindamycin+nicotinamide should not be given with muscle relaxants like atracurium, cisatracurium, doxacurium, metocurine, mivacurium, pancuronium, pipecuronium, rapacuronium, rocuronium, succinylcholine, tubocurarine and vecuronium.
Drug-Food Interaction: Avoid fried food or oil food.
Drug-Disease Interaction: You should not use Clindamycin+nicotinamide if you have ulcerative colitis, enteritis (inflammation of intestines) or severe diarrhoea caused by antibiotic medicine. People with colitis should avoid using Clindamycin+nicotinamide as it may cause severe, persistent diarrhoea and severe abdominal cramps with the passage of blood in stool or mucus.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
safe if prescribedThere are no interactions found with Clindamycin+nicotinamide pertaining to alcohol. However, it is advised to avoid alcohol for a speedy recovery.
Pregnancy
cautionThere are no well-established clinical studies with Clindamycin+nicotinamide in pregnant women. Hence, Clindamycin+nicotinamide should be used during pregnancy only if clearly needed. Consult your doctor before taking this medicine.
Breast Feeding
cautionClindamycin+nicotinamide is safe to use in breastfeeding. However, please inform your doctor that you are breastfeeding if you are prescribed Clindamycin+nicotinamide.
Driving
safe if prescribedThere are no effects found of Clindamycin+nicotinamide on driving capabilities.
Liver
cautionThere are no interactions found with Clindamycin+nicotinamide pertaining to the liver. However, please inform your doctor if you are suffering from or have suffered from liver diseases.
Kidney
cautionThere are no interactions found with Clindamycin+nicotinamide pertaining to the kidney. However, please inform your doctor if you are suffering from or have suffered from kidney diseases.
Children
safe if prescribedClindamycin+nicotinamide should be used in children only if prescribed by a specialist. The safety and effectiveness of Clindamycin+nicotinamide have not been established in children below 12 years of age.
Habit Forming
Diet & Lifestyle Advise
- Avoid fried food or oil food and drink plenty of water.
- It is advised to avoid unnecessary exposure to the sun.
- In case, it is necessary to go out in the sun, use sunscreen.
- Do not itch or scratch the infected area.
- Use moisturizer to prevent the occurrence of side effects.
- Exercise regularly to reduce stress.
Special Advise
Clindamycin+nicotinamide is for external use only and contact should be avoided from the eyes and mucous membranes, including those of the nose and mouth. In case of excessive dryness, irritation or peeling of the skin, please consult your doctor.
Patients Concern
Disease/Condition Glossary
Acne or acne vulgaris: It is a long-term skin problem that occurs when hair follicles become plugged with oil and dead skin cells. It leads to the formation of blackheads, whiteheads, pimples, oily skin and a scar on the uppermost layer of the skin (epidermis).
FAQs
Clindamycin+nicotinamide is used to treat acne. It works by killing the acne-causing bacteria and reducing the swelling, redness and tenderness caused by acne or pimples.
The precautions which should be taken while using Clindamycin+nicotinamide are to avoid showering/bathing for at least 1 hour after the application. Avoid contact of Clindamycin+nicotinamide with eyes and mucous membranes. Other topical products such as cosmetics, lotions, insect repellants, moisturizers or other topical medications should be avoided. Avoid unnecessary exposure to the sun, and if you have to go out in the sun, apply sunscreen.
Clindamycin+nicotinamide may take up to 2-3 weeks to show its effect. Use it as per the directions given by your doctor. In case there is no improvement in the symptoms, please consult your doctor.
The side effects of Clindamycin+nicotinamide include peeling, dryness, irritation, redness and burning sensation at the application site. If these side effects persist or worsen, please consult your doctor.
No, do not overuse Clindamycin+nicotinamide as it can cause severe diarrhea due to over-absorption of the medicine into the body. If you experience increased severity of your symptoms, please consult your doctor.
Store Clindamycin+nicotinamide in a cool and dry place. Keep it out of reach of children. Dispose of the unused medicine.
Clindamycin+nicotinamide should not be used to treat a single pimple as it is not a spot treatment. Apply Clindamycin+nicotinamide to the entire face. Use it once a day to help treat your acne.
It may take up to 2-3 weeks for your symptoms to improve and may take some time to show significant results. Use Clindamycin+nicotinamide as advised and let your doctor know if your symptoms do not improve or worsen.
Yes, Clindamycin+nicotinamide is very useful in controlling pimples and also helps in lightening the after marks.
Yes, Clindamycin+nicotinamide can be used every day in the doses prescribed by your doctor until your skin problem improves. Please avoid using it for a prolonged duration on skin.
