Brufonil Gel 20 gm

Brufonil Gel 20 gm belongs to the class of antibiotics known as lincomycin antibiotics, primarily used to treat inflamed acne. It minimizes the formation of excessive natural oil, known as sebum. It also reduces swelling caused due to acne. Acne is a skin-related problem in which oil glands (sebaceous glands) of the skin become clogged, thereby forming pimples and sometimes cysts.

Brufonil Gel 20 gm is composed of two medicines namely: Clindamycin and Nicotinamide. Clindamycin is a lincomycin antibiotic that penetrates the skin and helps kill acne-causing bacteria. On the other hand, Nicotinamide is a form of vitamin B which is responsible for exerting anti-inflammatory effects that are applied to the skin. Together, they help to reduce the swelling, redness and tenderness caused by acne or pimples. Besides this, it also prevents the formation of pimples, blackheads and whiteheads on the skin.

Brufonil Gel 20 gm meant for external use only. It should be applied in sufficient quantity enough to cover the affected area. Wash your hands before and after using this medicine. If accidentally it comes in contact with your eyes, nose, mouth or any other sensitive areas, immediately rinse it with water. In some cases, you may experience irritation, dryness, peeling, redness and burning sensation at the application site. Most of these side effects of Brufonil Gel 20 gm do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor. It is advised to use a skin moisturizer and drink plenty of water to prevent side effects.

Do not stop using this medicine without consulting your doctor. Inform your doctor if you are pregnant or breastfeeding. Also, if you are allergic to this medicine, please tell your doctor. Avoid touching, picking or scratching the infected area to avoid worsening of the acne. It is advised to avoid unnecessary sun exposure and before stepping out in the sun, use sunscreen. Do not use any kind of cosmetic products or get any cosmetic procedures done in the affected area without consulting your doctor.

Brufonil Gel 20 gm contains Clindamycin and Nicotinamide (Vitamin B3). Clindamycin is a well-known bacteriostatic antibiotic that treats acne, bacterial infection, and scars and is suitable for both dry and wet skin. It helps in the healing of acne by killing the acne-causing bacteria and prevents further bacterial skin infections. Nicotinamide is a synthetic form of Vitamin B3 that stimulates ceramide (fats found on the uppermost layer of the skin) synthesis and improves the epidermal permeability barrier functions, making skin look supple and soft.

• Irritation
• Dryness
• Peeling
• Redness
• Burning sensation at the application site

Brufonil Gel 20 gm is meant for topical use only and not for oral, ophthalmic or intravaginal use. You should not use a Brufonil Gel 20 gm if your skin is very sensitive or allergic to Brufonil Gel 20 gm or lincomycin class antibiotic. Do not apply Brufonil Gel 20 gm on the cut, scraped, sunburned or eczema-affected skin part. If accidentally Brufonil Gel 20 gm gets into your eyes, immediately rinse your eyes with water thoroughly and contact your doctor immediately if the irritation persists. Inform your doctor if your skin conditions do not improve. $ It may take time to treat acne, so do not apply a dosage more than prescribed for better and faster results. If you are pregnant, planning for pregnancy or a nursing mother, consult your doctor before using Brufonil Gel 20 gm. Consult the doctor if you are using dermatological products other than Brufonil Gel 20 gm, as it may lead to unfavourable results like excessive drying of the skin, peeling, irritation, etc.

Drug-Drug Interaction: This medicine may have an interaction with antibiotics (clarithromycin, rifampin, erythromycin), anti-HIV drug (indinavir, nelfinavir, ritonavir), antifungals (itraconazole, ketoconazole) and antidepressant (nefazodone). Besides this, Brufonil Gel 20 gm should not be given with muscle relaxants like atracurium, cisatracurium, doxacurium, metocurine, mivacurium, pancuronium, pipecuronium, rapacuronium, rocuronium, succinylcholine, tubocurarine and vecuronium. 

Drug-Food Interaction: Avoid fried food or oil food. 

Drug-Disease Interaction: You should not use Brufonil Gel 20 gm if you have ulcerative colitis, enteritis (inflammation of intestines) or severe diarrhoea caused by antibiotic medicine. People with colitis should avoid using Brufonil Gel 20 gm as it may cause severe, persistent diarrhoea and severe abdominal cramps with the passage of blood in stool or mucus.

• CLARITHROMYCIN
• RIFAMPIN
• ERYTHROMYCIN
• INDINAVIR
• NELFINAVIR
• RITONAVIR
• ITRACONAZOLE
• KETOCONAZOLE
• NEFAZODONE
• ATRACURIUM
• CISATRACURIUM
• DOXACURIUM
• METOCURINE
• MIVACURIUM
• PANCURONIUM
• PIPECURONIUM
• RAPACURONIUM
• ROCURONIUM
• SUCCINYLCHOLINE
• TUBOCURARINE
• VECURONIUM

• Avoid fried food or oil food and drink plenty of water.
• It is advised to avoid unnecessary exposure to the sun.
• In case, it is necessary to go out in the sun, use sunscreen.
• Do not itch or scratch the infected area.
• Use moisturizer to prevent the occurrence of side effects.
• Exercise regularly to reduce stress.

Brufonil Gel 20 gm is for external use only and contact should be avoided from the eyes and mucous membranes, including those of the nose and mouth. In case of excessive dryness, irritation or peeling of the skin, please consult your doctor.

Acne or acne vulgaris: It is a long-term skin problem that occurs when hair follicles become plugged with oil and dead skin cells. It leads to the formation of blackheads, whiteheads, pimples, oily skin and a scar on the uppermost layer of the skin (epidermis).