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Betamethasone+neomycin

About Betamethasone+neomycin

Betamethasone+neomycin is a combination medicine used to treat bacterial infections of the eye and ear like allergic conjunctivitis (inflammation of the mucous membrane (conjunctiva) of the eye), uveitis (inflammation of the uvea-middle layer of the eye), marginal keratitis (inflammation of the cornea), blepharitis (inflammation of the eyelids), and otitis externa (inflammation of the ear). Betamethasone+neomycin may also be used to treat steroid-responsive inflammation of the ear and nose. 

Betamethasone+neomycin is composed of two medicines: Betamethasone and Neomycin. Betamethasone belongs to the class of corticosteroids. It blocks the production of prostaglandins (chemical messengers) that make the affected area red, swollen and itchy. Neomycin is an aminoglycoside antibiotic that prevents bacteria from synthesising essential proteins required to carry out vital functions. It has broad-spectrum activity against aerobic gram-positive and gram-negative bacteria. 

Your doctor will advise the appropriate dose that suits your infection. Betamethasone+neomycin is for external use only. Common side effects of Betamethasone+neomycin include irritation, itching, redness, burning or a stinging sensation at the application site. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, consult a doctor.

Let your doctor know if you are sensitive to Betamethasone+neomycin or any other medications. Please inform your doctor if you have any undiagnosed red eye, pulmonary tuberculosis, hearing problems (ototoxicity) and a perforated eardrum before using Betamethasone+neomycin. Pregnant and breastfeeding mothers should consult the doctor before starting Betamethasone+neomycin. Betamethasone+neomycin should be used in children only when advised by a doctor, and their growth should be closely monitored since there are chances of delay in growth.

Uses of Betamethasone+neomycin

Treatment of Bacterial infections

Medicinal Benefits

Betamethasone+neomycin treats various bacterial infections like allergic conjunctivitis (inflammation of the mucous membrane (conjunctiva) of the eye), uveitis inflammation of the uvea (middle layer of the eye), marginal keratitis (inflammation of the cornea), blepharitis (inflammation of the eyelids), and otitis externa (inflammation of the ear). It may also be used to treat steroid-responsive inflammation of the ear and nose. Betamethasone+neomycin consists of Betamethasone (corticosteroid) and Neomycin (antibiotic). Betamethasone blocks prostaglandins production (chemical messengers) that make the affected area red, swollen, and itchy. Neomycin prevents the synthesis of essential proteins required by bacteria to carry out vital functions.

Directions for Use

Ear drops: Do not touch the dropper and hold it close to the ear by tilting your head to the side. Gently squeeze the dropper and instil the ear drops into the ear. Keep your head tilted for a minute to let the drops soak in. Eye drops: Tilt your head back and pull your lower eyelid downwards and outwards. Gently squeeze the dropper and instil the eye drops into the eye/eyes. Blink a few times to spread the medication inside your eye. Nasal drops: Tilt your head back and squeeze the nasal drops into the nostril/ nostrils. Keep your head tilted backwards and sniff gently.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Betamethasone+neomycin

Eye drops:

  • Irritation
  • Itching
  • Redness
  • Burning or a stinging sensation
  • Blurred vision
  • Drooping eyelids

Ear drops:

  • Ringing or buzzing in the ears
  • Itching

Nasal drops:

  • Headache
  • Dry or blocked nose
  • Irritation
  • Sneezing
  • Smell or taste changes
  • Dizziness

Drug Warnings

Before taking Betamethasone+neomycin, let your doctor know if you have a history of eye problems (glaucoma and cataract), heart, liver, or kidney diseases, undiagnosed red eye, pulmonary tuberculosis, hearing problems (ototoxicity) or a perforated eardrum. Avoid touching the dropper with bare hands since it contaminates the dropper tip and solution. If you wear contact lenses, please inform your doctor since eye drops may contain additives like Benzalkonium chloride that change the colour of the lens. It is advised to check with your doctor before using Betamethasone+neomycin if you are pregnant or breastfeeding. Betamethasone+neomycin should be used in children only when advised by a doctor.

Drug Interactions

Drug-Drug Interaction: Betamethasone+neomycin may interact with anti-HIV/AIDS drugs (ritonavir and cobicistat).

Drug-Food Interaction: No drug-food interactions were found.

Drug-Disease Interaction: Betamethasone+neomycin is not recommended in viral, fungal, ocular (eye) tuberculosis, purulent (pus discharge) conditions of the eye, glaucoma, and herpetic keratitis.

Drug-Drug Interactions Checker List:

  • RITONAVIR
  • COBICISTAT
  • Safety Advice

    • Safety Warning

      Alcohol

      caution

      Alcohol consumption may worsen the side effects like dizziness; hence please avoid or limit alcohol intake while being treated with Betamethasone+neomycin.

    • Safety Warning

      Pregnancy

      caution

      Caution is advised on topical usage of corticosteroids (Betamethasone) in pregnant women. It is recommended to consult your doctor if you plan to conceive or are already pregnant before starting Betamethasone+neomycin.

    • Safety Warning

      Breast Feeding

      caution

      There are limited studies on how Betamethasone+neomycin affects breastfed infants. Please consult your doctor before taking Betamethasone+neomycin if you are breastfeeding.

    • Safety Warning

      Driving

      caution

      Betamethasone+neomycin may cause side effects like blurry vision or dizziness, affecting your driving ability. Do not drive or operate machinery in such cases. Drive only when you are alert and have clear vision.

    • Safety Warning

      Liver

      caution

      Let your doctor know if you have any history of liver diseases or hepatic impairment before starting Betamethasone+neomycin.

    • Safety Warning

      Kidney

      caution

      Let your doctor know if you have any history of kidney diseases before starting Betamethasone+neomycin.

    • Safety Warning

      Children

      caution

      Betamethasone+neomycin should be used in children only when advised by a doctor, and their growth should be closely monitored since there are chances of delay in growth.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Manage stress, eat healthily, drink plenty of water, exercise regularly, and get plenty of sleep.
    • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
    • Know your allergy triggers, such as pollen, dust and other factors.
    • Avoid getting things like shampoo, soap, and water into the ear as it can cause itching.
    • Do not poke or scratch the ear as it can cause damage to the ear canal, leading to inflammation.
    • Do not rub your eyes even though some ophthalmic drugs make your eye itchy.
    • If you wear contact lenses, clean and replace contact lenses more often. Never share contact lenses. Always remember to wash your hands before inserting and after removing the contact lens. 
    • Avoid staring at the digital screens for longer durations. Rest your eyes every 20 minutes.
    • Avoid or limit the intake of alcohol and caffeine.

    Special Advise

    It is advised to contact your doctor if the infection symptoms persist or worsen after two weeks of treatment.

    Patients Concern

    Disease/Condition Glossary

    Bacterial eye infection: A bacterial eye infection occurs when bacteria invade any part of the eyeball or its surrounding tissues, including the cornea (clear front surface of the eye) and the conjunctiva (thin membrane lining the outer eye and inner eyelids). A bacterial eye infection symptoms include red eyes, pain, swelling of the eyes, watery eyes, itching, and blurry vision. Some very common eye infections are conjunctivitis (the inflammation and irritation of the eye's mucous membrane (conjunctiva), stye (bump on the eyelid), uveitis (inflammation of the uvea-middle layer of the eye), marginal keratitis (inflammation of the cornea), and blepharitis (inflammation of the eyelids).

    Bacterial ear infection: Bacterial ear infection occurs when bacteria infect the outer or middle ear. The most common bacterial strains that cause ear infections are Streptococcus pneumoniae and Haemophilus influenza. Symptoms include ear ache (sharp, sudden pain or a dull, continuous pain), feeling of fullness in the ear, ear drainage, and muffled hearing. Treatment may include over-the-counter painkillers, anti-allergic drugs, antibiotics, and steroids.

    FAQs

    Betamethasone+neomycin is a combination medicine used to treat bacterial infections of the eye and ear like allergic conjunctivitis (inflammation of the mucous membrane (conjunctiva) of the eye), uveitis (inflammation of the uvea-middle layer of the eye), marginal keratitis (inflammation of the cornea), blepharitis (inflammation of the eyelids), and otitis externa (inflammation of the ear). It may also be used to treat steroid-responsive inflammation of the ear and nose.

    Betamethasone+neomycin consists of Neomycin and Betamethasone. Neomycin is an antibiotic that prevents the synthesis of essential proteins required by bacteria to carry out vital functions. Betamethasone, a corticosteroid, works by blocking prostaglandins production (chemical messengers) that make the affected area red, swollen and itchy.

    If you are wearing contact lenses, it is advised to remove them while administering eye drops. Also, remember to wash your hands before and after administering eye drops to avoid contamination.

    If you use other eye ointments/drops along with Betamethasone+neomycin, it is advised to maintain a gap of at least 5-10 minutes after each administration. Also, use eye drops before applying any ointments.

    Please inform your doctor before using Betamethasone+neomycin if you have undiagnosed red eye, pulmonary tuberculosis, hearing problems (ototoxicity) and a perforated eardrum. Betamethasone+neomycin is not recommended in viral, fungal, ocular (eye) tuberculosis, purulent (pus discharge) conditions of the eye, glaucoma, and herpetic keratitis (infection of the cornea).

    Apply the drops as soon as possible. However, if it is time for the next dose, skip the missed dose and return to your regular dosing schedule.

    Available Medicines for

    Betamethasone+neomycin

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