Atorvastatin+glimepiride+metformin
About Atorvastatin+glimepiride+metformin
Atorvastatin+glimepiride+metformin is a combination medicine used to treat type 2 diabetes mellitus associated with dyslipidaemia. Atorvastatin+glimepiride+metformin has both lipid and glucose-lowering effects; this helps in lowering blood triglycerides and blood glucose levels as well.
Atorvastatin+glimepiride+metformin contains Atorvastatin, Glimepiride and Metformin. Atorvastatin raises good cholesterol and lowers bad cholesterol. Metformin aids the better use of existing insulin by decreasing the absorption and production of sugar in the body. Glimepiride lowers blood glucose by increasing the amount of insulin released by the pancreas.
In some cases, you may experience side effects such as nausea, diarrhoea, stomach pain, headache, muscle pain, and weakness. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are recommended to consult your doctor if the side effects persist or worsen.
Do not take Atorvastatin+glimepiride+metformin if you are allergic to any of its components. Consult your doctor if you are pregnant or breastfeeding. Keep your doctor informed about all the medications you are taking and your health condition to rule out any unpleasant side effects/interactions.
Uses of Atorvastatin+glimepiride+metformin
Medicinal Benefits
Atorvastatin+glimepiride+metformin is used to treat type 2 diabetes mellitus associated with dyslipidaemia. Atorvastatin+glimepiride+metformin contains Atorvastatin, Glimepiride and Metformin. Atorvastatin is an HMG-CoA reductase inhibitor (statin) that raises good cholesterol and lowers bad cholesterol. It slows the production of cholesterol in the body and decreases the build-up of cholesterol on artery walls. Metformin belongs to a class of medicines called biguanides that aids better use of existing insulin by decreasing the absorption and production of sugar in the body. Glimepiride is the preferred sulphonylurea in those with underlying cardiovascular disease (CAD). It lowers blood glucose by increasing the amount of insulin released by the pancreas. Atorvastatin+glimepiride+metformin has both lipid and glucose-lowering effects; this helps in lowering blood triglycerides and blood glucose levels as well.
Directions for Use
Storage
Side Effects of Atorvastatin+glimepiride+metformin
- Nausea
- Diarrhoea
- Stomach pain
- Headache
- Muscle pain
- Weakness
Drug Warnings
Do not take Atorvastatin+glimepiride+metformin if you are allergic to any of the components. Inform your doctor if you have glucose 6-phosphate dehydrogenase (G6PD) deficiency, infection, dehydration, heart problems, kidney or liver problems, if you drink alcohol or if you are due to undergo any surgery, including dental surgery. Consult your doctor if you are pregnant or breastfeeding. Let your doctor know if you are taking any other medicines, including vitamin/mineral supplements and herbal products.
Drug Interactions
Drug-Drug Interactions: Inform your doctor if you are taking diuretics (furosemide), anti-diabetic (insulin glargine, dapagliflozin, sitagliptin, empagliflozin, insulin detemir, semaglutide, dulaglutide, liraglutide), hormones (levothyroxine), antacid (esomeprazole), blood thinner (clopidogrel), pain killer (aspirin), beta-blocker (metoprolol).
Drug-Food Interactions: No interactions found/established.
Drug-Disease Interactions: Inform your doctor if you have rhabdomyolysis (damaging protein is released into the blood due to the breakdown of muscle tissue), lactic acidosis (build-up of lactic acid in the blood), glucose 6-phosphate dehydrogenase (G6PD) deficiency, or hypoglycaemia (low blood glucose levels).
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
cautionAlcohol may increase the risk of serious side effects. Ask your doctor whether you can consume alcoholic beverages while on treatment with this medicine.
Pregnancy
consult your doctorLimited information is available. Hence, if you are pregnant or planning for pregnancy, consult your doctor before taking Atorvastatin+glimepiride+metformin.
Breast Feeding
consult your doctorLimited information is available. Hence, if you are breastfeeding, consult your doctor before taking Atorvastatin+glimepiride+metformin.
Driving
cautionIt is unknown if Atorvastatin+glimepiride+metformin alters your ability to drive. Drive or operate machinery only if you are alert.
Liver
consult your doctorIf you have liver problems, inform your doctor before taking Atorvastatin+glimepiride+metformin.
Kidney
consult your doctorIf you have kidney impairment, inform your doctor before taking Atorvastatin+glimepiride+metformin.
Children
consult your doctorLimited information is available. Please consult your doctor.
Habit Forming
Diet & Lifestyle Advise
- Follow a cholesterol-lowering diet.
- Exercise regularly. It helps in maintaining proper weight and lowers cholesterol.
- Limit salt and sugar intake.
- Avoid smoking and alcohol consumption.
- Choose healthy fats and cut down on trans fat.
- Include omega-3 fatty acids, fibre-rich food, fruits and vegetables.
- Rest properly, and avoid stress by doing meditation or yoga.
Patients Concern
Disease/Condition Glossary
Diabetic dyslipidaemia: Diabetic dyslipidaemia is characterised by increased triglyceride levels, low-density lipoproteins (LDL) and decreased high-density lipoprotein (HDL) levels. This condition is common in people with type-2 diabetes mellitus. It is one of the major risk factors for cardiovascular disease in diabetic patients. Lifestyle, genetics, obesity, consumption of high saturated/trans fat, low thyroid levels, and kidney disease could be the cause of dyslipidaemia. Symptoms of diabetic dyslipidaemia include chest pain/tightness, indigestion, heartburn, dizziness, palpitations, shortness of breath, cold sweats, nausea, and vomiting.
FAQs
Atorvastatin+glimepiride+metformin is used to treat Type 2 diabetes mellitus associated with dyslipidaemia.
Atorvastatin+glimepiride+metformin decreases LDL (bad) cholesterol and increases HDL (good) cholesterol. It also increases the amount of insulin released by the pancreas and aids in better use of existing insulin. Thereby, Atorvastatin+glimepiride+metformin lowers blood triglycerides and blood glucose levels as well.
To treat your condition effectually, continue taking Atorvastatin+glimepiride+metformin for as long as your doctor has prescribed it. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Atorvastatin+glimepiride+metformin.
If you miss a dose, take it as soon as you remember. However, if it is almost time for the scheduled dose, skip the missed dose and take the scheduled dose instead.
The common side effects of Atorvastatin+glimepiride+metformin include nausea, diarrhoea, stomach pain, headache, muscle pain, and weakness. Most of these side effects do not require medical attention and will resolve gradually over time. However, if the side effects persist or worsen, please consult your doctor.
When you have high cholesterol, it's important to follow a cholesterol-lowering diet that is rich in fibre, whole grains, lean proteins, and healthy fats, such as olive oil and nuts. Include plenty of vegetables and choose low-fat dairy products to support healthy cholesterol levels. Additionally, incorporate omega-3-rich foods like fish into your diet. Limit or avoid saturated and trans fats, added sugars, and refined carbohydrates, such as red meat, full-fat dairy, processed snacks, and sugary drinks. By making these dietary changes, you can help manage your cholesterol levels and improve your overall health.
If you have diabetes, avoid sugary drinks, processed foods, and unhealthy habits like smoking and excessive alcohol consumption. Also, limit foods that can cause a spike in blood sugar levels, such as white rice and corn. By making these changes, you can better manage your diabetes and improve your overall health. Consult your doctor for personalized advice.
Frequent low blood sugar (hypoglycaemia) could be caused by several factors, such as taking too much insulin or other diabetes medications, irregular meal patterns, overexertion yourself physically without enough food, or taking diabetes medications while fasting. It may also be related to underlying conditions like adrenal or pituitary insufficiency (which occurs when the adrenal or pituitary glands fail to produce adequate amounts of certain hormones) or, in rare cases, a tumour affecting insulin production. Additionally, excessive alcohol consumption or certain medications can interfere with blood sugar regulation. It is essential to consult a doctor for an accurate diagnosis and proper management.
