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About Zavicefta Injection
Zavicefta Injection belongs to a class of medicines called antibiotics used in the treatment of bacterial infections of the urinary tract, respiratory tract and abdomen. A bacterial infection is a condition in which harmful bacteria grow in the body and cause infection. Bacteremia is the presence of bacteria in the blood.
Zavicefta Injection contains Ceftazidime and Avibactam. Ceftazidime works by interfering with the formation of the bacterial cell wall (a protective covering) that is necessary for their survival. Avibactam decreases bacterial resistance and enhances the activity of Ceftazidime against the bacteria. Together, Zavicefta Injection helps to treat bacterial infections.
In some cases, you may experience redness and swelling at the site of injection, and/or nausea and diarrhoea. Most of these side effects of Zavicefta Injection do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
If you are allergic to Zavicefta Injection or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, please inform your doctor before taking Zavicefta Injection. Drive only if you are alert as Zavicefta Injection may cause dizziness. Zavicefta Injection should be used with caution in those with renal impairment and Clostridium difficile-associated diarrhoea.
Uses of Zavicefta Injection
Directions for Use
Medicinal Benefits
Zavicefta Injection contains Ceftazidime and Avibactam; they act against both aerobic (grow in the presence of oxygen) and anaerobic (grow in the absence of oxygen) gram-negative and gram-positive bacteria. It is used in the treatment of bacterial infections of the urinary tract, respiratory tract, and abdomen. Ceftazidime inhibits enzymes that regulate the formation of the bacterial cell wall, thereby arresting bacterial development. Avibactam is a beta-lactamase inhibitor. Beta-lactamase is an enzyme that inactivates antibiotics and builds up a drug resistance. By inhibiting beta-lactamase, avibactam makes the bacteria more susceptible to antibiotic action. Zavicefta Injection damages the bacterial cell wall, kills bacteria and makes the bacteria more sensitive to the action of the antibiotic. Hence Zavicefta Injection finds widespread use in treating complicated bacterial infections.
How Zavicefta Injection Works
Storage
Side Effects of Zavicefta Injection
What if I have taken an overdose of Zavicefta Injection
Drug Warnings
If you are allergic to Zavicefta Injection or any other medicines, please tell your doctor. If you have kidney problems or diabetes, inform your doctor before taking Zavicefta Injection. Consult your doctor if you are pregnant or breastfeeding. If you are on a controlled sodium diet, inform your doctor before taking Zavicefta Injection. Zavicefta Injection should not be administered if you are currently on any vaccinations or are scheduled for the same. If you have a widespread rash with peeling skin and blisters, please consult a doctor immediately as these might be signs of Stevens-Johnson syndrome. Drive only if you are alert as Zavicefta Injection may cause dizziness. You are recommended to complete the full course of Zavicefta Injection as prescribed by your doctor for effective results.
Drug-Drug Interactions
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Product Substitutes
Alcohol
Caution
The interaction of Zavicefta Injection with alcohol is unknown. Please consult a doctor before consuming alcohol while using Zavicefta Injection.
Pregnancy
Caution
Please consult a doctor if you are pregnant or planning for pregnancy. Your doctor will prescribe only if the benefits outweigh the risks.
Breast Feeding
Caution
Zavicefta Injection may be excreted in human milk in small amounts. Therefore, it is given to breastfeeding mothers only if the doctor thinks benefits are greater than risks. Please consult a doctor if you are breastfeeding.
Driving
Caution
Zavicefta Injection may cause dizziness. Therefore, avoid driving if you feel dizzy after taking Zavicefta Injection.
Liver
Caution
Take Zavicefta Injection with caution, especially if you have a history of liver diseases/conditions. The dose may be adjusted by your doctor as required.
Kidney
Caution
Take Zavicefta Injection with caution, especially if you have a history of kidney diseases/conditions. The dose may be adjusted by your doctor as required.
Children
Caution
Zavicefta Injection should be used in children only in doses as prescribed by a doctor. Zavicefta Injection is not recommended for use in children below 3months.
Zavicefta Injection belongs to a class of medicines called antibiotics used in the treatment of bacterial infections of the urinary tract, respiratory tract and abdomen.
Zavicefta Injection works by damaging the bacterial cell wall (protective covering) that is necessary for their survival and by increasing bacterial sensitivity.
Zavicefta Injection may cause diarrhoea as a common side effect. However, if the condition persists, worsens or if you notice blood or mucus in stools, avoid taking Zavicefta Injection and consult a doctor immediately.
Exercise caution while taking Zavicefta Injection with diuretics/water tablets. You are not advised to take Zavicefta Injection with a diuretic called furosemide as co-administration of these two medicines may increase the risk of kidney problems, especially in patients with kidney impairment and also when Zavicefta Injection is given in high doses. However, please consult your doctor before taking Zavicefta Injection with other medicines.
Zavicefta Injection is not used to treat viral infections. Zavicefta Injection is an antibiotic that is used to treat only bacterial infections.
Zavicefta Injection is given through an IV (intravenous) line, which means it is injected directly into a vein. A healthcare provider administers it in a hospital or clinic, with the dose and duration depending on the specific infection being treated. It should not be self-administered.
Zavicefta Injection is safe for children when used at the prescribed doses by a doctor. However, it is not recommended for children under 3 months of age.
Before receiving Zavicefta Injection, you must inform your doctor if you are allergic to foods or medicines. You should also inform your doctor if you have kidney problems or diabetes or if you are pregnant or breastfeeding. If you are on a controlled sodium diet, let your doctor know before starting the medication. Also, inform your doctor if you are receiving or scheduled to receive any vaccinations.
The common side effects of Zavicefta Injection include nausea, diarrhoea, and redness and swelling at the site of injection. These side effects are usually temporary, and not everyone will experience them. In most cases, they resolve on their own without the need for medical treatment. However, if the side effects persist or worsen, please consult your doctor for further advice and management.
If a bacterial infection is not treated, the bacteria can continue to grow and spread throughout the body. This may lead to serious health complications, such as damage to vital organs or tissues. In severe cases, it can result in sepsis (a life-threatening, body-wide infection). Additionally, the infection may become harder to treat over time, as the bacteria can develop resistance to antibiotics. It is important to seek medical treatment to prevent these risks and help your body recover.
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