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Written By , M Pharmacy
Reviewed By , MPharma., PhD
Last Updated Jan 1, 2025 | 2:46 PM IST
Zivictam Injection is an antibiotic used in treating bacterial infections. This medicine stops the growth of bacteria and thereby helps reduce various bacterial infections of the urinary tract, respiratory tract and abdomen. This medicine is not effective for treating viral infections. Common side effects include diarrhoea, nausea & vomiting. This medicine is not effective for the treatment of viral infections.
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Prescription drug

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Manufacturer/Marketer :

Converge Biotech Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

3 Days Returnable

Expires on or after :

Apr-26

About Zivictam Injection

Zivictam Injection belongs to a class of medicines called antibiotics used in the treatment of bacterial infections of the urinary tract, respiratory tract and abdomen. A bacterial infection is a condition in which harmful bacteria grow in the body and cause infection. Bacteremia is the presence of bacteria in the blood.

Zivictam Injection contains Ceftazidime and Avibactam. Ceftazidime works by interfering with the formation of the bacterial cell wall (a protective covering) that is necessary for their survival. Avibactam decreases bacterial resistance and enhances the activity of Ceftazidime against the bacteria. Together, Zivictam Injection helps to treat bacterial infections.

In some cases, you may experience redness and swelling at the site of injection, and/or nausea and diarrhoea. Most of these side effects of Zivictam Injection do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Zivictam Injection or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, please inform your doctor before taking Zivictam Injection. Drive only if you are alert as Zivictam Injection may cause dizziness. Zivictam Injection should be used with caution in those with renal impairment and Clostridium difficile-associated diarrhoea.

Uses of Zivictam Injection

Treatment of Bacterial infections

Medicinal Benefits

Zivictam Injection contains Ceftazidime and Avibactam; they act against both aerobic (grow in the presence of oxygen) and anaerobic (grow in the absence of oxygen) gram-negative and gram-positive bacteria. It is used in the treatment of bacterial infections of the urinary tract, respiratory tract, and abdomen. Ceftazidime inhibits enzymes that regulate the formation of the bacterial cell wall, thereby arresting bacterial development. Avibactam is a beta-lactamase inhibitor. Beta-lactamase is an enzyme that inactivates antibiotics and builds up a drug resistance. By inhibiting beta-lactamase, avibactam makes the bacteria more susceptible to antibiotic action. Zivictam Injection damages the bacterial cell wall, kills bacteria and makes the bacteria more sensitive to the action of the antibiotic. Hence Zivictam Injection finds widespread use in treating complicated bacterial infections.

Side Effects of Zivictam Injection

  • Redness and swelling on injection site
  • Diarrhoea
  • Dizziness
  • Nausea

Directions for Use

Zivictam Injection will be administered by a healthcare professional; Do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

If you are allergic to Zivictam Injection or any other medicines, please tell your doctor. If you have kidney problems or diabetes, inform your doctor before taking Zivictam Injection. Consult your doctor if you are pregnant or breastfeeding. If you are on a controlled sodium diet, inform your doctor before taking Zivictam Injection. Zivictam Injection should not be administered if you are currently on any vaccinations or are scheduled for the same. If you have a widespread rash with peeling skin and blisters, please consult a doctor immediately as these might be signs of Stevens-Johnson syndrome. Drive only if you are alert as Zivictam Injection may cause dizziness. You are recommended to complete the full course of Zivictam Injection as prescribed by your doctor for effective results.

Therapeutic Class

ANTIBIOTICS

Drug-Drug Interactions

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CeftizoximeCholera, live attenuated
Severe
CeftizoximeCholera vaccines
Severe

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Diet & Lifestyle Advise

  • Take probiotics after completing the full course of Zivictam Injection to restore some healthy bacteria in the intestines that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like cheese, yoghurt, kombucha, sauerkraut and kimchi can help to restore the good bacteria of the intestine.
  • Include fibre-rich foods, as they can be easily digested by your gut bacteria, which helps stimulate their growth. Whole grains such as whole-grain bread, brown rice should be included in your diet.
  • Make sure you drink plenty of water or other fluids every day while you are taking Zivictam Injection.
  • Avoid alcohol consumption as it may increase adverse effects.

Habit Forming

No

How Zivictam Injection Works

Zivictam Injection contains Ceftazidime and Avibactam. Ceftazidime works by interfering with the formation of the bacterial cell wall (a protective covering) that is necessary for their survival. Avibactam decreases bacterial resistance and enhances the activity of Ceftazidime against the bacteria. Together, Zivictam Injection helps to treat bacterial infections.

What if I have taken an overdose of Zivictam Injection

The overdose of Zivictam Injection is unlikely as it is administered by a doctor. However, if you suspect any adverse reactions or unusual symptoms while on treatment with Zivictam Injection, please inform your doctor immediately.
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Alcohol

Caution

The interaction of Zivictam Injection with alcohol is unknown. Please consult a doctor before consuming alcohol while using Zivictam Injection.

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Pregnancy

Caution

Please consult a doctor if you are pregnant or planning for pregnancy. Your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Zivictam Injection may be excreted in human milk in small amounts. Therefore, it is given to breastfeeding mothers only if the doctor thinks benefits are greater than risks. Please consult a doctor if you are breastfeeding.

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Driving

Caution

Zivictam Injection may cause dizziness. Therefore, avoid driving if you feel dizzy after taking Zivictam Injection.

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Liver

Caution

Take Zivictam Injection with caution, especially if you have a history of liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Zivictam Injection with caution, especially if you have a history of kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

Zivictam Injection should be used in children only in doses as prescribed by a doctor. Zivictam Injection is not recommended for use in children below 3months.

Country of origin

India

Manufacturer/Marketer address

7-2-1813/5/a1 UNo 1 , 2nd floor, Classic Arcade Rd, Czech Colony, Sanath Nagar IE, Sanath Nagar, Hyderabad, Telangana 500018
Other Info - ZIV0083

Author Details

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FAQs

Zivictam Injection belongs to a class of medicines called antibiotics used in the treatment of bacterial infections of the urinary tract, respiratory tract and abdomen.
Zivictam Injection works by damaging the bacterial cell wall (protective covering) that is necessary for their survival and by increasing bacterial sensitivity.
Zivictam Injection may cause diarrhoea as a common side effect. However, if the condition persists, worsens or if you notice blood or mucus in stools, avoid taking Zivictam Injection and consult a doctor immediately.
Exercise caution while taking Zivictam Injection with diuretics/water tablets. You are not advised to take Zivictam Injection with a diuretic called furosemide as co-administration of these two medicines may increase the risk of kidney problems, especially in patients with kidney impairment and also when Zivictam Injection is given in high doses. However, please consult your doctor before taking Zivictam Injection with other medicines.
Zivictam Injection is not used to treat viral infections. Zivictam Injection is an antibiotic that is used to treat only bacterial infections.
Zivictam Injection is given through an IV (intravenous) line, which means it is injected directly into a vein. A healthcare provider administers it in a hospital or clinic, with the dose and duration depending on the specific infection being treated. It should not be self-administered.
Zivictam Injection is safe for children when used at the prescribed doses by a doctor. However, it is not recommended for children under 3 months of age.
Before receiving Zivictam Injection, you must inform your doctor if you are allergic to foods or medicines. You should also inform your doctor if you have kidney problems or diabetes or if you are pregnant or breastfeeding. If you are on a controlled sodium diet, let your doctor know before starting the medication. Also, inform your doctor if you are receiving or scheduled to receive any vaccinations.
The common side effects of Zivictam Injection include nausea, diarrhoea, and redness and swelling at the site of injection. These side effects are usually temporary, and not everyone will experience them. In most cases, they resolve on their own without the need for medical treatment. However, if the side effects persist or worsen, please consult your doctor for further advice and management.
If a bacterial infection is not treated, the bacteria can continue to grow and spread throughout the body. This may lead to serious health complications, such as damage to vital organs or tissues. In severe cases, it can result in sepsis (a life-threatening, body-wide infection). Additionally, the infection may become harder to treat over time, as the bacteria can develop resistance to antibiotics. It is important to seek medical treatment to prevent these risks and help your body recover.

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