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Zilias Injection 1's

Zilias Injection 1's

Prescription drug
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Manufacturer/Marketer

Intas Pharmaceuticals Ltd

Consume Type

PARENTERAL

Return Policy

Returnable

Expires on or after

Apr-26

About Zilias Injection

Zilias Injection belongs to a class of medicines called antibiotics used in the treatment of bacterial infections of the urinary tract, respiratory tract and abdomen. A bacterial infection is a condition in which harmful bacteria grow in the body and cause infection. Bacteremia is the presence of bacteria in the blood.

Zilias Injection contains Ceftazidime and Avibactam. Ceftazidime works by interfering with the formation of the bacterial cell wall (a protective covering) that is necessary for their survival. Avibactam decreases bacterial resistance and enhances the activity of Ceftazidime against the bacteria. Together, Zilias Injection helps to treat bacterial infections.

In some cases, you may experience redness and swelling at the site of injection, and/or nausea and diarrhoea. Most of these side effects of Zilias Injection do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Zilias Injection or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, please inform your doctor before taking Zilias Injection. Drive only if you are alert as Zilias Injection may cause dizziness. Zilias Injection should be used with caution in those with renal impairment and Clostridium difficile-associated diarrhoea.

Uses of Zilias Injection

Treatment of Bacterial infections

Medicinal Benefits

Zilias Injection contains Ceftazidime and Avibactam; they act against both aerobic (grow in the presence of oxygen) and anaerobic (grow in the absence of oxygen) gram-negative and gram-positive bacteria. It is used in the treatment of bacterial infections of the urinary tract, respiratory tract, and abdomen. Ceftazidime inhibits enzymes that regulate the formation of the bacterial cell wall, thereby arresting bacterial development. Avibactam is a beta-lactamase inhibitor. Beta-lactamase is an enzyme that inactivates antibiotics and builds up a drug resistance. By inhibiting beta-lactamase, avibactam makes the bacteria more susceptible to antibiotic action. Zilias Injection damages the bacterial cell wall, kills bacteria and makes the bacteria more sensitive to the action of the antibiotic. Hence Zilias Injection finds widespread use in treating complicated bacterial infections.

Directions for Use

Zilias Injection will be administered by a healthcare professional; Do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Zilias Injection

  • Redness and swelling on injection site
  • Diarrhoea
  • Dizziness
  • Nausea

Drug Warnings

If you are allergic to Zilias Injection or any other medicines, please tell your doctor. If you have kidney problems or diabetes, inform your doctor before taking Zilias Injection. Consult your doctor if you are pregnant or breastfeeding. If you are on a controlled sodium diet, inform your doctor before taking Zilias Injection. Zilias Injection should not be administered if you are currently on any vaccinations or are scheduled for the same. If you have a widespread rash with peeling skin and blisters, please consult a doctor immediately as these might be signs of Stevens-Johnson syndrome. Drive only if you are alert as Zilias Injection may cause dizziness. You are recommended to complete the full course of Zilias Injection as prescribed by your doctor for effective results.

Drug Interactions

Drug-Drug Interaction: Zilias Injection may interact with gout therapy (probenecid), antibiotics (chloramphenicol, tobramycin, gentamicin) and water tablets (furosemide).

Drug-Food Interaction: No interactions found.

Drug-Disease Interaction: If you have kidney problems or diabetes, inform your doctor before taking Zilias Injection.

Drug-Drug Interactions Checker List

  • PROBENECID
  • CHLORAMPHENICOL
  • TOBRAMYCIN
  • GENTAMICIN
  • FUROSEMIDE

Habit Forming

No

Diet & Lifestyle Advise

  • Take probiotics after completing the full course of Zilias Injection to restore some healthy bacteria in the intestines that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like cheese, yoghurt, kombucha, sauerkraut and kimchi can help to restore the good bacteria of the intestine.
  • Include fibre-rich foods, as they can be easily digested by your gut bacteria, which helps stimulate their growth. Whole grains such as whole-grain bread, brown rice should be included in your diet.
  • Make sure you drink plenty of water or other fluids every day while you are taking Zilias Injection.
  • Avoid alcohol consumption as it may increase adverse effects.

Special Advise

  • Regular kidney function tests are recommended, especially in patients with kidney problems while taking Zilias Injection so that the dose may be adjusted accordingly.
  • If you are about to undergo any blood or urine tests, inform your doctor that you are taking Zilias Injection as it may interfere with these tests.
  • Zilias Injection may interact with certain tests such as glucose (sugar) in urine and coomb’s test (blood test), resulting in unusual results. Therefore, inform the lab technician that you are taking Zilias Injection before undergoing any tests.

Disease/Condition Glossary

Bacterial Infection: A bacterial infection is a condition in which harmful bacteria enter, multiply, and infect our body. Infectious or harmful bacteria can make you sick and reproduce quickly in your body. These harmful bacteria produce chemicals known as toxins, which can damage tissue and make you sick. It can target any body part and multiply very quickly. When you get infected with bacteria, you can experience generalized symptoms, like fevers, chills, and fatigue.

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Alcohol

Caution

The interaction of Zilias Injection with alcohol is unknown. Please consult a doctor before consuming alcohol while using Zilias Injection.

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Pregnancy

Caution

Please consult a doctor if you are pregnant or planning for pregnancy. Your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Zilias Injection may be excreted in human milk in small amounts. Therefore, it is given to breastfeeding mothers only if the doctor thinks benefits are greater than risks. Please consult a doctor if you are breastfeeding.

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Driving

Caution

Zilias Injection may cause dizziness. Therefore, avoid driving if you feel dizzy after taking Zilias Injection.

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Liver

Caution

Take Zilias Injection with caution, especially if you have a history of liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Zilias Injection with caution, especially if you have a history of kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

Zilias Injection should be used in children only in doses as prescribed by a doctor. Zilias Injection is not recommended for use in children below 3months.

Country of origin

India

Manufacturer/Marketer address

Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Other Info -

Author Details

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FAQs

Zilias Injection works by damaging the bacterial cell wall (protective covering) that is necessary for their survival and by increasing bacterial sensitivity.
Zilias Injection may cause diarrhoea as a common side effect. However, if the condition persists, worsens or if you notice blood or mucus in stools, avoid taking Zilias Injection and consult a doctor immediately.
Exercise caution while taking Zilias Injection with diuretics/water tablets. You are not advised to take Zilias Injection with a diuretic called furosemide as co-administration of these two medicines may increase the risk of kidney problems, especially in patients with kidney impairment and also when Zilias Injection is given in high doses. However, please consult your doctor before taking Zilias Injection with other medicines.
Zilias Injection is not used to treat viral infections. Zilias Injection is an antibiotic that is used to treat only bacterial infections.

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