Uptonin Nasal Spray is primarily indicated for the treatment of postmenopausal osteoporosis in women more than five years postmenopause when alternative therapies are unsuitable. Post-menopausal osteoporosis is a medical condition that causes thinning and weakening of the bones during/after a menopausal period.

Uptonin Nasal Spray contains Calcitonin, a human hormone that prevents bone breakdown and increases bone density (thickness). Thus, it helps treat osteoporosis in postmenopausal women.

Use Uptonin Nasal Spray as prescribed by the doctor. Uptonin Nasal Spray may cause certain side effects such as hypocalcemia, runny nose, nosebleed, sinus pain, application site reactions such as rhinitis (stuffy nose), epistaxis (nose bleeds) and other nasal symptoms, back pain, arthralgia (Joint pain) and headache. Most of these side effects do not require medical attention and gradually resolve over time. However, if these side effects persist longer, please consult your doctor.

Uptonin Nasal Spray is for intranasal use only; do not inject or take it orally. Before using Uptonin Nasal Spray, inform your doctor of all your medical conditions, sensitivities, and medications. Uptonin Nasal Spray is intended for post-menopausal women; therefore, it should not be recommended for other populations. Avoid drinking alcohol because it affects how the body absorbs calcium and vitamin D, which are essential for good bone formation.

Insert the tip of the bottle into a nostril while closing the other nostril and spray towards the sides of the nostril. Keep your head straight and breathe gently. Repeat the same process for another nostril.

Uptonin Nasal Spray contains Calcitonin, a calcitonin receptor agonist that prevents the loss of bones that happens after menopause and helps to rebuild bones. Calcitonin is a hormone that the C-cells in the thyroid gland produce and release. It opposes the parathyroid hormone's action, helping regulate the blood’s calcium and phosphate levels. Uptonin Nasal Spray works by suppressing the activity of the osteoclasts (cells that break down bone). When the osteoclasts break down bone tissue, the calcium enters the bloodstream. Uptonin Nasal Spray lessens the amount of calcium in the blood by preventing the breakdown of bone. Thereby, Uptonin Nasal Spray strengthens the bones and minimizes the risk of fractures. Uptonin Nasal Spray also seems to decrease the amount of calcium the kidneys can re-absorb, lowering calcium levels further.

• Rhinitis (stuffy nose)
• Epistaxis (nose bleeds)
• Application site reactions
• Back pain
• Arthralgia (joint pain)
• Headache

Before using Uptonin Nasal Spray, Inform your doctor about all your medical conditions, sensitivities, and all medications you are using. Uptonin Nasal Spray is intended for post-menopausal women; therefore, Uptonin Nasal Spray should not be recommended for other populations. In rare situations, individuals using Uptonin Nasal Spray may be affected with anaphylactic shock (a sudden, severe, life-threatening allergic reaction leading to difficulty breathing); if you encounter it, stop using Uptonin Nasal Spray and contact your doctor immediately.

• Consume calcium-rich foods like milk, yoghurt, cheese, green leafy vegetables, fish with bones such as salmon, sardines, calcium-fortified cereals and orange juice.
• Exposure to sunlight helps synthesise vitamin D, which is essential for strong bones and muscles.
• Eating vitamin-D-rich foods such as egg yolks, salmon, oily fish like sardines, and mackerel.
• Indulging in regular exercise to prevent bone loss. Activities include brisk walking, dancing, jogging, and strength training exercises like lifting weights and using weight machines or elastic bands.
• Engaging in activities for stress relief, such as meditation and yoga.
• Preserving a healthy weight eases pressure on the bones.
• Taking medications if one is at risk for osteoporosis.
• Quitting smoking and limiting alcohol consumption.