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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Unicontin-E 400 Tablet is used for the management of asthma and chronic obstructive pulmonary disease (COPD). It contains Theophylline, which works by relaxing the airway in the lungs and making it easier to breathe. In some cases, you may experience side effects such as nausea, vomiting, restlessness, tremors, headache, muscle cramps, and increased heart rate. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Composition :

THEOPHYLLINE-400MG

Manufacturer/Marketer :

Modi Mundipharma Pvt Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Unicontin-E 400 Tablet

Unicontin-E 400 Tablet is a respiratory medicine which belongs to the class of 'Xanthine' primarily used for the management of asthma and chronic obstructive pulmonary disease (COPD). Asthma is a breathing problem in which airways narrow, swell and may produce extra mucus, which may lead to breathing difficulty and trigger cough, a whistling sound (wheezing) when you breathe out and shortness of breath. COPD is a group of progressive lung diseases, most commonly emphysema (shortness of breath) and chronic bronchitis (inflammation and irritation of bronchial tubes). Initially, it may be mild, but in severe cases, it can lead to total blockage of airways and damage to the lungs.

Unicontin-E 400 Tablet contains Theophylline, which helps in the treatment of asthma and chronic obstructive pulmonary disease (COPD). Theophylline works by relaxing the airway in the lungs and making it easier to breathe. In addition to this, theophylline also helps in treating the symptoms hence making it easier to treat. It is generally a long-term treatment.

You should take Unicontin-E 400 Tablet without food, mostly on an empty stomach. It should be swallowed whole with a glass of water. Do not chew, bite, or break it. Your doctor will advise you on how often you take your tablets based on your medical condition. In some cases, you may experience nausea, vomiting, restlessness, tremors, headache, muscle cramps, and increased heart rate. Most of these side effects of Unicontin-E 400 Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Try not to stop taking this medicine of your own. Let your doctor know about this, as it may cause withdrawal symptoms. Do not take this medicine if you have any lung disease, muscle weakness (myasthenia gravis), sleeping disorder, difficulty in sleeping (sleep apnoea), severe liver disease, or problem with alcohol or other prescription recreational drugs. Unicontin-E 400 Tablet is a habit-forming drug, and hence, there is a risk of dependence on this medicine. So, before stopping this medicine, contact a doctor as it may cause withdrawal symptoms like anxiety, increased heart rate, tremors, or general unwell feeling.

Uses of Unicontin-E 400 Tablet

Treatment of Asthma, Chronic obstructive pulmonary disease (COPD)

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Unicontin-E 400 Tablet contains Theophylline, which helps in the treatment of asthma and chronic obstructive pulmonary disease (COPD). Theophylline works by relaxing the airway in the lungs and making it easier to breathe. In addition to this, theophylline also helps in treating the symptoms hence making it easier to treat. It is generally a long-term treatment.

How Unicontin-E 400 Tablet Works

Unicontin-E 400 Tablet contains Theophylline, which helps in the treatment of asthma and chronic obstructive pulmonary disease (COPD). Theophylline works by relaxing the airway in the lungs and making it easier to breathe. In addition to this, theophylline also helps in treating the symptoms hence making it easier to treat. It is generally a long-term treatment.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Unicontin-E 400 Tablet

  • Vomiting

  • Diarrhoea

  • Indigestion

  • Dizziness

What if I have taken an overdose of Unicontin-E 400 Tablet

Do not take more than the prescribed dose of Unicontin-E 400 Tablet as it may cause overdose. The symptoms of overdose include slow heart rate, seizures (fits), fainting or weak pulse. Seizures caused due to overdose of Theophylline may cause permanent brain damage or it can be fatal. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Do not take this medicine if you have any lung disease, muscle weakness (myasthenia gravis), sleeping disorder or difficulty in sleeping (sleep apnoea), severe liver disease, or problem with alcohol or other prescription recreational drugs. Unicontin-E 400 Tablet is a habit-forming drug, so there is a risk of dependence on this medicine. So, before stopping this medicine, contact a doctor as it may cause withdrawal symptoms like anxiety, increased heart rate, tremors, or general unwell feeling.

Drug-Drug Interactions

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TheophyllineRiociguat
Critical
TheophyllineMetoprolol Tartrate
Severe

Drug-Drug Interactions

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TheophyllineRiociguat
Critical
How does the drug interact with Unicontin-E 400 Tablet 10's:
Co-administration of Unicontin-E 400 Tablet 10's with Riociguat can increase the risk of low blood pressure.

How to manage the interaction:
Taking Unicontin-E 400 Tablet 10's with Riociguat is not recommended but can be taken together if prescribed by a doctor. However, consult a doctor if you experience dizziness, lightheadedness, fainting, flushing (a sudden reddening of the face), headache, and nasal congestion (stuffy nose). Do not discontinue any medications without consulting a doctor.
TheophyllineMetoprolol Tartrate
Severe
How does the drug interact with Unicontin-E 400 Tablet 10's:
Taking Metoprolol Tartrate with Unicontin-E 400 Tablet 10's could make Metoprolol Tartrate less effective and increase the side effects of Unicontin-E 400 Tablet 10's

How to manage the interaction:
Although taking metoprolol tartrate and Unicontin-E 400 Tablet 10's together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience symptoms such as nausea, vomiting, insomnia, tremors, restlessness, uneven heartbeats, or difficulty breathing, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
TheophyllineMetoprolol Succinate
Severe
How does the drug interact with Unicontin-E 400 Tablet 10's:
Taking Metoprolol Succinate with Unicontin-E 400 Tablet 10's, could make Metoprolol Succinate less effective and enhance the effects of Unicontin-E 400 Tablet 10's.

How to manage the interaction:
Although taking metoprolol succinate and Unicontin-E 400 Tablet 10's together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience symptoms such as nausea, vomiting, insomnia, shaking of hands and legs, restlessness, uneven heartbeats, or difficulty breathing, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
TheophyllineTramadol
Severe
How does the drug interact with Unicontin-E 400 Tablet 10's:
Co-administration of tramadol with Unicontin-E 400 Tablet 10's can increase the effect of tramadol.

How to manage the interaction:
Taking Unicontin-E 400 Tablet 10's with tramadol together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience any symptoms such as confusion, hallucination, seizure, increased heart rate, blurred vision, tremors, incoordination, stomach cramps, nausea, vomiting, and diarrhea, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
TheophyllineLabetalol
Severe
How does the drug interact with Unicontin-E 400 Tablet 10's:
Taking Labetalol with Unicontin-E 400 Tablet 10's may reduce the effectiveness of Labetalol and increase Unicontin-E 400 Tablet 10's's effects.

How to manage the interaction:
Although taking Labetalol and Unicontin-E 400 Tablet 10's together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience sleeplessness, shaking, irregular heartbeats, or trouble breathing, consult a doctor. Do not discontinue any medications without a doctor's advice.
TheophyllineCarvedilol
Severe
How does the drug interact with Unicontin-E 400 Tablet 10's:
Taking carvedilol with Unicontin-E 400 Tablet 10's, could make carvedilol less effective and increase the effects of Unicontin-E 400 Tablet 10's.

How to manage the interaction:
Although Carvedilol and Unicontin-E 400 Tablet 10's can result in an interaction, it can be taken if a doctor has advised it. However, if you experience vomiting, restlessness, palpitations, or difficulty breathing, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
TheophyllineMexiletine
Severe
How does the drug interact with Unicontin-E 400 Tablet 10's:
Co-administration of Unicontin-E 400 Tablet 10's with mexiletine can increase the effect of mexiletine. This can increase the risk or severity of side effects.

How to manage the interaction:
Taking Unicontin-E 400 Tablet 10's with Mexiletine can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience any symptoms such as nausea, vomiting, diarrhea, loss of appetite, headache, tremor, confusion, restlessness, insomnia, seizures, heart palpitations, and/or irregular heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
TheophyllineBetaxolol
Severe
How does the drug interact with Unicontin-E 400 Tablet 10's:
Taking Betaxolol with Unicontin-E 400 Tablet 10's, could increase the risk of side effects.

How to manage the interaction:
Although taking Betaxolol and Unicontin-E 400 Tablet 10's together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sleeplessness, tremors (Involuntary shaking or movement affecting hands, legs, and face), restlessness, uneven heartbeats, or difficulty breathing, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
TheophyllineCiprofloxacin
Severe
How does the drug interact with Unicontin-E 400 Tablet 10's:
Taking Unicontin-E 400 Tablet 10's with ciprofloxacin may increase the blood levels of Unicontin-E 400 Tablet 10's, which increases the risk of side effects.

How to manage the interaction:
Although taking ciprofloxacin and Unicontin-E 400 Tablet 10's together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, if you experience nausea, vomiting, diarrhea, lack of appetite, headache, tremor(shaking of hands & legs), confusion, restlessness, sleeplessness, seizures(fits), irregular heartbeat, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
TheophyllineAtenolol
Severe
How does the drug interact with Unicontin-E 400 Tablet 10's:
Using atenolol with Unicontin-E 400 Tablet 10's, could increase the effects of Unicontin-E 400 Tablet 10's.

How to manage the interaction:
Taking atenolol and Unicontin-E 400 Tablet 10's together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, insomnia, shaking of hands and legs, restlessness, uneven heartbeats, or difficulty breathing, contact the doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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THEOPHYLLINE-400MGCaffeine containing foods/drinks
Moderate

Drug-Food Interactions

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THEOPHYLLINE-400MGCaffeine containing foods/drinks
Moderate
Common Foods to Avoid:
Cocoa, Coffee, Dark Chocolate, Energy Drinks With Caffeine, Green Tea, Kola Nut, Tea, Tiramisu

How to manage the interaction:
Caffeine consumption can modify Unicontin-E 400 Tablet 10's blood levels. Caffeine should be avoided in excess while using Unicontin-E 400 Tablet 10's. Consult a doctor if you suffer any symptoms such as headaches, sleeplessness, or increases in blood pressure or heart rate. Do not discontinue any medications without consulting a doctor.

Diet & Lifestyle Advise

  • Eat a healthy diet specially green leafy vegetables and strictly do not consume alcohol, caffeine (coffee, tea and cola drinks and chocolate). Here Caffeine is a stimulant and can decrease Unicontin-E 400 Tablet ’s calming effects and alcohol can enhance Unicontin-E 400 Tablet 's effects.
  • Smoking should be avoided while taking Unicontin-E 400 Tablet as it can alter the blood levels of theophylline, which may affect the dosing.
  • It is very important to maintain hygiene like washing hands after coming from outside as people with asthma/COPD are at a greater risk to infections.
  • Stay active and do regular exercise to improve quality of life and increase tolerance to shortness of breath.
  • Talk with family member if you feel low or are stressed as it helps to improve symptoms of COPD and keep it under control.
  • Shortness of breath can be eased by doing pursed lip breathing exercise. In this, just relax your neck and shoulder muscles, breathe in with your nose for two seconds and breathe out through pursed lips for four seconds. Such exercises will help you to improve your breath.

Habit Forming

No

Therapeutic Class

ANTIHYPONATREMIC

Unicontin-E 400 Tablet Substitute

Substitutes safety advice
  • UNICONTIN 400MG TABLET

    17.73per tablet
  • Onimar 400 Tablet

    by AYUR

    4.28per tablet
  • Theoday 400mg Tablet

    2.46per tablet
  • Zvtho 400mg Tablet

    5.02per tablet
  • Theofil 400mg Capsule

    4.49per tablet
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Alcohol

Caution

Alcohol can alter the way Unicontin-E 400 Tablet works. Please consult your doctor if you intend to drink alcohol whilst taking Unicontin-E 400 Tablet .

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Pregnancy

Safe if prescribed

If you are breastfeeding do not take Unicontin-E 400 Tablet until you have talked to your doctor.

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Breast Feeding

Safe if prescribed

If you are pregnant do not take Unicontin-E 400 Tablet until you have talked to your doctor.

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Driving

Unsafe

Unicontin-E 400 Tablet usually causes dizziness, drowsiness and visual disturbances which may affect their ability to drive or operate machinery. So, do not drive or operate heavy machinery if you feel sleepy or dizzy after taking Unicontin-E 400 Tablet . Tell your doctor if you get these types of side effects.

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Liver

Caution

Unicontin-E 400 Tablet to be taken with caution, especially if you have a history of liver disease. The dose may have to be adjusted by your doctor.

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Kidney

Safe if prescribed

Unicontin-E 400 Tablet does not have any reported interaction; hence, in case you experience any difficulty discuss with your doctor.

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Children

Caution

Children under six years of age should not take Unicontin-E 400 Tablet .

FAQs

Unicontin-E 400 Tablet is used to manage asthma and chronic obstructive pulmonary disease (COPD).
Unicontin-E 400 Tablet contains Theophylline, which relaxes the lungs' airways and makes breathing easier.
If you remember within 4 hours of the time Unicontin-E 400 Tablet was due, take Unicontin-E 400 Tablet straight away. Take your next dose at your normal time. Do not take a double dose to make up for a forgotten does of Unicontin-E 400 Tablet .
Yes, Unicontin-E 400 Tablet can lead to withdrawl symptoms. So, it should not be stopped abruptly. Consult your doctor and your dose might be lowered if required.
No, dose of Unicontin-E 400 Tablet should not be increased without consulting your doctor as it may increase risk of hypokalemia (high blood potassium level) which may lead to side effects of Unicontin-E 400 Tablet and also effect its efficacy.
No, you should not take Unicontin-E 400 Tablet if you have ulcers as it may worsen your ulcers and lead to bleeding and inflammation. So, please consult your doctor before starting Unicontin-E 400 Tablet as dose adjustment may be required.
Unicontin-E 400 Tablet is contraindicated in patients who are allergic to any of its ingredients. It is advised to avoid taking Unicontin-E 400 Tablet and beta-blockers like propranolol together at once.
No, Unicontin-E 400 Tablet should not be taken with any medication, if you are taking it for seizures it might worsen your condition and lead to symptoms like confusion, trouble talking, tremors or twitching, loss of muscle tone or tense muscles.
You will probably be prescribed Unicontin-E 400 Tablet for a long time. Do not stop taking them unless your doctor tells you to, even if you feel better.
Unicontin-E 400 Tablet may cause side effects such as vomiting, diarrhoea, dizziness and indigestion. If these side effects persist or worsen, please consult your doctor.
Take Unicontin-E 400 Tablet as advised by your doctor. Swallow it as a whole with a glass of water. Do not break, crush or chew it.
Unicontin-E 400 Tablet starts working quickly and you may see an improvement in symptoms within about 30 minutes of taking it. However, it may take a little longer about 4 to 8 hours to show full effect. If there is no considerable improvement in your symptoms, consult your doctor.
While taking Unicontin-E 400 Tablet , you should avoid foods high in caffeine such as cocoa, tea, coffee, and chocolate as these foods increase Unicontin-E 400 Tablet side effects. Also, you should avoid alcohol and tobacco. If you have any concerns regarding food restriction, please discuss with your doctor.

Country of origin

INDIA

Manufacturer/Marketer address

Ground Floor Modi Tower, 98, Nehru Place, New Delhi, Delhi 110019
Other Info - UNI0027

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