Unicontin-E 400 Tablet is a respiratory medicine which belongs to the class of 'Xanthine' primarily used for the management of asthma and chronic obstructive pulmonary disease (COPD). Asthma is a breathing problem in which airways narrow, swell and may produce extra mucus, which may lead to breathing difficulty and trigger cough, a whistling sound (wheezing) when you breathe out and shortness of breath. COPD is a group of progressive lung diseases, most commonly emphysema (shortness of breath) and chronic bronchitis (inflammation and irritation of bronchial tubes). Initially, it may be mild, but in severe cases, it can lead to total blockage of airways and damage to the lungs.

Unicontin-E 400 Tablet contains Theophylline, which helps in the treatment of asthma and chronic obstructive pulmonary disease (COPD). Theophylline works by relaxing the airway in the lungs and making it easier to breathe. In addition to this, theophylline also helps in treating the symptoms hence making it easier to treat. It is generally a long-term treatment.

You should take Unicontin-E 400 Tablet without food, mostly on an empty stomach. It should be swallowed whole with a glass of water. Do not chew, bite, or break it. Your doctor will advise you on how often you take your tablets based on your medical condition. In some cases, you may experience nausea, vomiting, restlessness, tremors, headache, muscle cramps, and increased heart rate. Most of these side effects of Unicontin-E 400 Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Try not to stop taking this medicine of your own. Let your doctor know about this, as it may cause withdrawal symptoms. Do not take this medicine if you have any lung disease, muscle weakness (myasthenia gravis), sleeping disorder, difficulty in sleeping (sleep apnoea), severe liver disease, or problem with alcohol or other prescription recreational drugs. Unicontin-E 400 Tablet is a habit-forming drug, and hence, there is a risk of dependence on this medicine. So, before stopping this medicine, contact a doctor as it may cause withdrawal symptoms like anxiety, increased heart rate, tremors, or general unwell feeling.

Unicontin-E 400 Tablet contains Theophylline, which helps in the treatment of asthma and chronic obstructive pulmonary disease (COPD). Theophylline works by relaxing the airway in the lungs and making it easier to breathe. In addition to this, theophylline also helps in treating the symptoms hence making it easier to treat. It is generally a long-term treatment.

• Vomiting

• Diarrhoea

• Indigestion

• Dizziness

Do not take this medicine if you have any lung disease, muscle weakness (myasthenia gravis), sleeping disorder or difficulty in sleeping (sleep apnoea), severe liver disease, or problem with alcohol or other prescription recreational drugs. Unicontin-E 400 Tablet is a habit-forming drug, so there is a risk of dependence on this medicine. So, before stopping this medicine, contact a doctor as it may cause withdrawal symptoms like anxiety, increased heart rate, tremors, or general unwell feeling.

Drug-Drug Interactions: This medicine interacts with asthma or breathing medicine (aminophylline, salbutamol, terbutaline or salmeterol), oral contraceptives, antidepressant (St. John’s Wort), anticancer (aminoglutethimide, methotrexate or lomustine), high blood pressure medicine (adenosine, moracizine, diltiazem, isoprenaline, mexiletine, propafenone, propranolol, verapamil), sleeping pills (benzodiazepines), stomach ulcers medicines (cimetidine or nizatidine), antibiotics (ciprofloxacin, clarithromycin, erythromycin, norfloxacin, ofloxacin), and treat alcoholism (disulfiram).

Drug-Food Interactions: While taking Unicontin-E 400 Tablet alcohol, food/drinks containing caffeine should not be used along with Unicontin-E 400 Tablet as it may affect the efficacy of Unicontin-E 400 Tablet .

Drug-Disease Interactions: Unicontin-E 400 Tablet should be taken with caution if you have high blood pressure or any other heart problems, overactive thyroid gland (hyperthyroidism), stomach ulcer, liver problems,  seizures (fits) or convulsions, fever, viral infection, alcoholism, male and have difficulty in passing urine (due to an enlarged prostate gland).

• SALMETEROL
• METHOTREXATE
• DILTIAZEM
• CIMETIDINE
• CIPROFLOXACIN
• ERYTHROMYCIN
• NORFLOXACIN
• OFLOXACIN
• DISULFIRAM
• VERAPAMIL
• PROPRANOLOL
• PROPAFENONE
• SALBUTAMOL
• CLARITHROMYCIN

• Eat a healthy diet specially green leafy vegetables and strictly do not consume alcohol, caffeine (coffee, tea and cola drinks and chocolate). Here Caffeine is a stimulant and can decrease Unicontin-E 400 Tablet ’s calming effects and alcohol can enhance Unicontin-E 400 Tablet 's effects.
• Smoking should be avoided while taking Unicontin-E 400 Tablet as it can alter the blood levels of theophylline, which may affect the dosing.
• It is very important to maintain hygiene like washing hands after coming from outside as people with asthma/COPD are at a greater risk to infections.
• Stay active and do regular exercise to improve quality of life and increase tolerance to shortness of breath.
• Talk with family member if you feel low or are stressed as it helps to improve symptoms of COPD and keep it under control.
• Shortness of breath can be eased by doing pursed lip breathing exercise. In this, just relax your neck and shoulder muscles, breathe in with your nose for two seconds and breathe out through pursed lips for four seconds. Such exercises will help you to improve your breath.

Asthma: It is a breathing problem in which airways narrow, swell and may produce extra mucus, which may lead to breathing difficulty and trigger cough, a whistling sound (wheezing) when you breathe out and shortness of breath.

COPD: It is a group of progressive lung diseases, most commonly emphysema (shortness of breath) and chronic bronchitis (inflammation and irritation of bronchial tubes). Initially, it may be mild, but in severe cases, it can lead to total blockage of airways and damage to the lungs.