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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Jan 1, 2025 | 2:45 PM IST
Topowin 2.5 mg Injection contains topotecan which is used in the treatment of ovarian and small cell lung cancer. It is an anticancer medicine which works by binding to the cell's DNA, and stops it from naturally dividing and functioning, ultimately destroying it. This medicine can sometimes be used for treating other cancer conditions aswell. Common side effects inculde nausea, diarrhoea, vomiting, thrombocytopenia (a low platelet count), peripheral neuropathy and electrolyte disturbance.
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Prescription drug

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Composition :

TOPOTECAN-2.5MG

Manufacturer/Marketer :

Nelwin Lifesciences

Consume Type :

PARENTERAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Topowin 2.5 mg Injection

Topowin 2.5 mg Injection belongs to a group of medicines called 'anti-cancer/anti-neoplastic agents', used to treat ovarian and small cell lung cancer. On the other hand, it may use to treat advanced cervical cancer if surgery or radiotherapy treatment is not possible. It may sometimes be used to treat other cancers. Ovarian cancer begins in the ovaries (a pair of female reproductive glands in which the ova, or eggs, are formed). Small-cell lung cancer is a disease in which malignant (cancer) cells form in the lung tissues.

Topowin 2.5 mg Injection contains 'Topotecan'. It works by penetrating into the cell wall and binding to the cell's DNA, stopping it from naturally dividing and functioning, ultimately destroying it. These medicines target cancer cells because they often affect rapidly dividing cells.

The amount of medicine that you will receive depends on many factors, including your height and weight, your general health or other health problems, and the type of cancer or condition being treated. Your doctor will determine your dose and schedule. Topowin 2.5 mg Injection is prescribed by a doctor experienced in the use of medications to treat cancer. You may sometimes experience nausea, diarrhoea, vomiting, thrombocytopenia (a low platelet count), peripheral neuropathy (nerves malfunction), nephrotoxicity at high doses, and electrolyte disturbances. Most of these side effects of Topowin 2.5 mg Injection do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

To treat your condition effectually, continue taking Topowin 2.5 mg Injection for as long as your doctor has prescribed. Do not stop using the Topowin 2.5 mg Injection midway. Talk to your doctor before taking Topowin 2.5 mg Injection if you have severe allergic reactions to Topowin 2.5 mg Injection or other medicines or suffer from severe lung problems, Infections, renal dysfunction, hepatic disorders and blood cell counts are too low. Avoid taking Topowin 2.5 mg Injection if you are pregnant or breastfeeding because this Topowin 2.5 mg Injection can cause harmful effects on the unborn baby. Both women and men using this Topowin 2.5 mg Injection should use birth control to avoid pregnancy.

Uses of Topowin 2.5 mg Injection

Treatment of Ovarian cancer and Small cell lung cancer

Directions for Use

Topowin 2.5 mg Injection will be administered by a qualified healthcare professional. Hence, do not self-administer.

Medicinal Benefits

Topowin 2.5 mg Injection contains 'Topotecan', which belongs to a group of anti-cancer medicines used to treat ovarian cancer and small cell lung cancer. It works by damaging the genetic material (DNA) of the cancer cells, which stops their growth and multiplication. It can be used alone or together with other chemotherapy drugs depending on the type of cancer you have.

How Topowin 2.5 mg Injection Works

Topowin 2.5 mg Injection contains 'Topotecan'. It works by penetrating into the cell wall and binding to the cell's DNA, stopping it from naturally dividing and functioning, ultimately destroying it. These medicines target cancer cells because they often affect rapidly dividing cells.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Topowin 2.5 mg Injection

  • Feeling generally weak and tired (temporary anaemia)
  • Low white blood cell count (neutropenia)
  • Unusual bruising or bleeding
  • Weight loss and loss of appetite (anorexia)
  • Tiredness
  • Weakness
  • Feeling sick (nausea)
  • Being sick (vomiting)
  • Diarrhoea
  • Stomach pain
  • Constipation
  • Inflammation and ulcers of the mouth, tongue or gums
  • Inflammation and ulcers of the mouth, tongue or gums
  • High body temperature (fever)
  • Hair loss
  • Headache
  • Allergic or hypersensitivity reactions (rash)
  • Yellow skin
  • Itching sensation
  • Feeling unwell (malaise)
  • Deficiency of the blood (pancytopenia)

What if I have taken an overdose of Topowin 2.5 mg Injection

Topowin 2.5 mg Injection is a parenteral formulation, hence the chance of overdose may be less. However, keep track of your medicine as an overdose of Topowin 2.5 mg Injection may cause serious side effects such as myelosuppression, increased hepatic enzymes, etc. Seek immediate medical attention if you observe any of these side effects. If an overdose is suspected, observe the patient.

Drug Warnings

Topowin 2.5 mg Injection will be administered by a healthcare professional. To treat your condition effectually, continue taking Topowin 2.5 mg Injection for as long as your doctor has prescribed. Do not stop Topowin 2.5 mg Injection midway. Talk to your doctor before taking Topowin 2.5 mg Injection if you have severe allergic reactions to Topowin 2.5 mg Injection or other medicines or suffer from severe lung problems, Infections, renal dysfunction, thrombocytopenia (a low platelet count), neutropenia (low white blood cell count), hepatic disorders. Topowin 2.5 mg Injection should not be employed in patients with severe bone marrow depression or significant bleeding. Avoid taking Topowin 2.5 mg Injection if you are pregnant or breastfeeding because this Topowin 2.5 mg Injection can cause harmful effects on the unborn baby. Both women and men using this Topowin 2.5 mg Injection should use birth control to avoid pregnancy. Peripheral blood counts should be frequently monitored during Topowin 2.5 mg Injection treatment and appropriate until recovery is achieved. Do not receive any kind of immunization or vaccination without your doctor's approval while taking the Topowin 2.5 mg Injection.

Drug-Drug Interactions

verifiedApollotooltip
TopotecanEtanercept
Severe
TopotecanClozapine
Severe

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Diet & Lifestyle Advise

  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Performing yoga may also help in improving both physical and mental health.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs.
  • Get optimal sleep; rest well.
  • Avoid smoking and alcohol consumption.
  • Avoid fast food, fried food, processed meats, refined carbs and added sugars.

Habit Forming

No

Therapeutic Class

ANTINEOPLASTIC

Topowin 2.5 mg Injection Substitute

Substitutes safety advice
  • Topotec 2.5Mg Inj

    by AYUR

    5391.50per tablet
  • Admatop 2.5 Injection 1's

    5034.10per tablet
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Alcohol

Unsafe

Avoid alcohol consumption while on treatment with Topowin 2.5 mg Injection.

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Pregnancy

Unsafe

Topowin 2.5 mg Injection should not be used during pregnancy because it can harm your fetus (newborn baby). Both women of childbearing potential and men must use an effective contraception method while taking Topowin 2.5 mg Injection and at least for six months later treatment. Your doctor will weigh the benefits and risks before prescribing this medicine.

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Breast Feeding

Unsafe

Topowin 2.5 mg Injection should not be used during breastfeeding as it passes into the breastmilk and may harm your baby. Hence, if you are breastfeeding, inform your doctor before receiving this medicine.

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Driving

Caution

Topowin 2.5 mg Injection may affect your reactions and your ability to drive.Note: Possible side effects of chemotherapy with Topowin 2.5 mg Injection may occur, such as nausea and vomiting. If you are affected by these side effects, do not drive and/or operate machines that require your alertness.

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Liver

Caution

If you have had a history or evidence of liver impairment, please inform your doctor before taking the Topowin 2.5 mg Injection. Your doctor may adjust the dose or prescribe a suitable alternative if necessary based on your condition.

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Kidney

Caution

If you have had a history or evidence of kidney diseases, please inform your doctor before taking the Topowin 2.5 mg Injection. Your doctor may adjust the dose or prescribe a suitable alternative if necessary based on your condition.

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Children

Unsafe

The safety and effectiveness of Topowin 2.5 mg Injection in pediatric patients have not been established. Please consult your doctor. Your doctor will weigh the benefits and any potential risks before prescribing this medicine.

FAQs

Topowin 2.5 mg Injection belongs to a group of medicines called anti-cancer drugs used in the treatment of ovarian cancer and small cell lung cancer. It is also used to treat advanced cervical cancer if surgery or radiotherapy treatment is not possible.
Topowin 2.5 mg Injection contains 'Topotecan'. Topotecan works by breaching the cellular wall and binding to the cell’s DNA, preventing the cell from dividing and functioning normally, which eventually kills the cell.
If you are allergic to topotecan or any other ingredients in this medication, are breastfeeding, or have too low blood cell counts, you should not use Topowin 2.5 mg Injection.
Yes, Topowin 2.5 mg Injection can cause low neutrophils levels, a type of white blood cells that help fight infections. If your white blood cells become low, you can be at higher risk for infections. Tell your doctor if you develop a fever or have an infection.
Avoid taking Topowin 2.5 mg Injection if you are pregnant because Topowin 2.5 mg Injection can cause harmful effects on the unborn baby. Females should follow effective birth control methods during treatment and at least six months after the final dose of Topowin 2.5 mg Injection.
The live vaccine may not work while on treatment with Topowin 2.5 mg Injection. Do not have immunizations/vaccinations without talking to your doctor first. Also, avoid contact with people who recently had immunizations /vaccinations.
Topowin 2.5 mg Injection is used to treat ovarian or small cell lung cancer that has come back after chemotherapy. On the other hand, it can also treat advanced cervical cancer if surgery or radiotherapy treatment is not possible. When treating cervical cancer, Topowin 2.5 mg Injection is used with another medication called cisplatin.

Country of origin

India
Other Info - TOP0512

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