apollo
0
Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 9, 2024 | 12:36 PM IST
Topotec 2.5Mg Inj contains topotecan which is used in the treatment of ovarian and small cell lung cancer. It is an anticancer medicine which works by binding to the cell's DNA, and stops it from naturally dividing and functioning, ultimately destroying it. This medicine can sometimes be used for treating other cancer conditions aswell. Common side effects inculde nausea, diarrhoea, vomiting, thrombocytopenia (a low platelet count), peripheral neuropathy and electrolyte disturbance.
Read more
Prescription drug

Whats That

tooltip
Prescription drug
 Trailing icon
Consult Doctor

Composition

TOPOTECAN-2.5MG

Manufacturer/Marketer

Unitech Health Care Pvt Ltd

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Topotec 2.5Mg Inj

Topotec 2.5Mg Inj belongs to a group of medicines called 'anti-cancer/anti-neoplastic agents', used to treat ovarian and small cell lung cancer. On the other hand, it may use to treat advanced cervical cancer if surgery or radiotherapy treatment is not possible. It may sometimes be used to treat other cancers. Ovarian cancer begins in the ovaries (a pair of female reproductive glands in which the ova, or eggs, are formed). Small-cell lung cancer is a disease in which malignant (cancer) cells form in the lung tissues.

Topotec 2.5Mg Inj contains 'Topotecan'. It works by penetrating into the cell wall and binding to the cell's DNA, stopping it from naturally dividing and functioning, ultimately destroying it. These medicines target cancer cells because they often affect rapidly dividing cells.

The amount of medicine that you will receive depends on many factors, including your height and weight, your general health or other health problems, and the type of cancer or condition being treated. Your doctor will determine your dose and schedule. Topotec 2.5Mg Inj is prescribed by a doctor experienced in the use of medications to treat cancer. You may sometimes experience nausea, diarrhoea, vomiting, thrombocytopenia (a low platelet count), peripheral neuropathy (nerves malfunction), nephrotoxicity at high doses, and electrolyte disturbances. Most of these side effects of Topotec 2.5Mg Inj do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

To treat your condition effectually, continue taking Topotec 2.5Mg Inj for as long as your doctor has prescribed. Do not stop using the Topotec 2.5Mg Inj midway. Talk to your doctor before taking Topotec 2.5Mg Inj if you have severe allergic reactions to Topotec 2.5Mg Inj or other medicines or suffer from severe lung problems, Infections, renal dysfunction, hepatic disorders and blood cell counts are too low. Avoid taking Topotec 2.5Mg Inj if you are pregnant or breastfeeding because this Topotec 2.5Mg Inj can cause harmful effects on the unborn baby. Both women and men using this Topotec 2.5Mg Inj should use birth control to avoid pregnancy.

Uses of Topotec 2.5Mg Inj

Treatment of Ovarian cancer and Small cell lung cancer

Medicinal Benefits

Topotec 2.5Mg Inj contains 'Topotecan', which belongs to a group of anti-cancer medicines used to treat ovarian cancer and small cell lung cancer. It works by damaging the genetic material (DNA) of the cancer cells, which stops their growth and multiplication. It can be used alone or together with other chemotherapy drugs depending on the type of cancer you have.

Directions for Use

Topotec 2.5Mg Inj will be administered by a qualified healthcare professional. Hence, do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Topotec 2.5Mg Inj

  • Feeling generally weak and tired (temporary anaemia)
  • Low white blood cell count (neutropenia)
  • Unusual bruising or bleeding
  • Weight loss and loss of appetite (anorexia)
  • Tiredness
  • Weakness
  • Feeling sick (nausea)
  • Being sick (vomiting)
  • Diarrhoea
  • Stomach pain
  • Constipation
  • Inflammation and ulcers of the mouth, tongue or gums
  • Inflammation and ulcers of the mouth, tongue or gums
  • High body temperature (fever)
  • Hair loss
  • Headache
  • Allergic or hypersensitivity reactions (rash)
  • Yellow skin
  • Itching sensation
  • Feeling unwell (malaise)
  • Deficiency of the blood (pancytopenia)

Drug Warnings

Topotec 2.5Mg Inj will be administered by a healthcare professional. To treat your condition effectually, continue taking Topotec 2.5Mg Inj for as long as your doctor has prescribed. Do not stop Topotec 2.5Mg Inj midway. Talk to your doctor before taking Topotec 2.5Mg Inj if you have severe allergic reactions to Topotec 2.5Mg Inj or other medicines or suffer from severe lung problems, Infections, renal dysfunction, thrombocytopenia (a low platelet count), neutropenia (low white blood cell count), hepatic disorders. Topotec 2.5Mg Inj should not be employed in patients with severe bone marrow depression or significant bleeding. Avoid taking Topotec 2.5Mg Inj if you are pregnant or breastfeeding because this Topotec 2.5Mg Inj can cause harmful effects on the unborn baby. Both women and men using this Topotec 2.5Mg Inj should use birth control to avoid pregnancy. Peripheral blood counts should be frequently monitored during Topotec 2.5Mg Inj treatment and appropriate until recovery is achieved. Do not receive any kind of immunization or vaccination without your doctor's approval while taking the Topotec 2.5Mg Inj.

Drug Interactions

Drug-Drug Interactions: Topotec 2.5Mg Inj interacts with medicines used in the treatment of chemotherapy (e.g. Paclitaxel), angiogenesis inhibitors (e.g. bevacizumab) and anti-tumour antibiotic medications (e.g. Doxorubicin).

Drug-Food Interactions: Avoid the consumption of alcohol and caffeine while taking Topotec 2.5Mg Inj.

Drug-Disease Interactions: Inform your doctor before taking the Topotec 2.5Mg Inj. It requires close monitoring if you suffer from Infections (bacterial/fungal/protozoal/viral), bleeding disorders, myelosuppression, bone marrow depression/low blood counts, renal dysfunction or disorders, interstitial lung disease, and diarrhoea.

Drug-Drug Interactions Checker List

  • PACLITAXEL
  • BEVACIZUMAB

Habit Forming

No

Diet & Lifestyle Advise

  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Performing yoga may also help in improving both physical and mental health.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs.
  • Get optimal sleep; rest well.
  • Avoid smoking and alcohol consumption.
  • Avoid fast food, fried food, processed meats, refined carbs and added sugars.

Special Advise

  • Topotec 2.5Mg Inj should be taken under strict medical supervision. The doctor will regularly monitor your condition while taking Topotec 2.5Mg Inj.
  • Your doctor may get routine blood tests done to monitor your liver function, electrolyte levels, and blood cell count in your blood.
  • Peripheral blood counts should be frequently monitored during Topotec 2.5Mg Inj treatment and, when appropriate until recovery is achieved.
  • Avoid unnecessary or prolonged exposure to sunlight and UV light (such as tanning booths) and wear protective clothing, sunglasses, and sunscreen. Topotec 2.5Mg Inj may make your skin sensitive to sunlight.

Disease/Condition Glossary

Cancer: Cancer is a condition where cells in a specific body part grow and reproduce uncontrollably. The cancerous cells can invade and destroy surrounding healthy tissue, including organs. Cancer sometimes begins in one body part before spreading to other areas.

Ovarian cancer: Ovarian cancer is a type of cancer that begins in the ovaries (one of a pair of female reproductive glands in which the ova, or eggs, are formed).

Small cell lung cancer: Small cell lung cancer is a disease in which malignant (cancer) cells form in the lung tissues.

bannner image

Alcohol

Unsafe

Avoid alcohol consumption while on treatment with Topotec 2.5Mg Inj.

bannner image

Pregnancy

Unsafe

Topotec 2.5Mg Inj should not be used during pregnancy because it can harm your fetus (newborn baby). Both women of childbearing potential and men must use an effective contraception method while taking Topotec 2.5Mg Inj and at least for six months later treatment. Your doctor will weigh the benefits and risks before prescribing this medicine.

bannner image

Breast Feeding

Unsafe

Topotec 2.5Mg Inj should not be used during breastfeeding as it passes into the breastmilk and may harm your baby. Hence, if you are breastfeeding, inform your doctor before receiving this medicine.

bannner image

Driving

Caution

Topotec 2.5Mg Inj may affect your reactions and your ability to drive.Note: Possible side effects of chemotherapy with Topotec 2.5Mg Inj may occur, such as nausea and vomiting. If you are affected by these side effects, do not drive and/or operate machines that require your alertness.

bannner image

Liver

Caution

If you have had a history or evidence of liver impairment, please inform your doctor before taking the Topotec 2.5Mg Inj. Your doctor may adjust the dose or prescribe a suitable alternative if necessary based on your condition.

bannner image

Kidney

Caution

If you have had a history or evidence of kidney diseases, please inform your doctor before taking the Topotec 2.5Mg Inj. Your doctor may adjust the dose or prescribe a suitable alternative if necessary based on your condition.

bannner image

Children

Unsafe

The safety and effectiveness of Topotec 2.5Mg Inj in pediatric patients have not been established. Please consult your doctor. Your doctor will weigh the benefits and any potential risks before prescribing this medicine.

Country of origin

INDIA

Manufacturer/Marketer address

28, Shiv Shakti Nagar, Near Indo Bharat School,, Gautam Marg, Nirman Nagarm, Jaipur, Rajasthan 302019
Other Info - TOP0233

Author Details

Doctor imageWe provide you with authentic, trustworthy and relevant information

FAQs

Topotec 2.5Mg Inj belongs to a group of medicines called anti-cancer drugs used in the treatment of ovarian cancer and small cell lung cancer. It is also used to treat advanced cervical cancer if surgery or radiotherapy treatment is not possible.
Topotec 2.5Mg Inj contains 'Topotecan'. Topotecan works by breaching the cellular wall and binding to the cell’s DNA, preventing the cell from dividing and functioning normally, which eventually kills the cell.
If you are allergic to topotecan or any other ingredients in this medication, are breastfeeding, or have too low blood cell counts, you should not use Topotec 2.5Mg Inj.
Yes, Topotec 2.5Mg Inj can cause low neutrophils levels, a type of white blood cells that help fight infections. If your white blood cells become low, you can be at higher risk for infections. Tell your doctor if you develop a fever or have an infection.
Avoid taking Topotec 2.5Mg Inj if you are pregnant because Topotec 2.5Mg Inj can cause harmful effects on the unborn baby. Females should follow effective birth control methods during treatment and at least six months after the final dose of Topotec 2.5Mg Inj.
The live vaccine may not work while on treatment with Topotec 2.5Mg Inj. Do not have immunizations/vaccinations without talking to your doctor first. Also, avoid contact with people who recently had immunizations /vaccinations.
Topotec 2.5Mg Inj is used to treat ovarian or small cell lung cancer that has come back after chemotherapy. On the other hand, it can also treat advanced cervical cancer if surgery or radiotherapy treatment is not possible. When treating cervical cancer, Topotec 2.5Mg Inj is used with another medication called cisplatin.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
icon image

Keep Refrigerated. Do not freeze.Prepaid payment required.

Add to Cart