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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

TIROBAN 5MG INJECTION is used to Prevent blood clots, heart attacks, and chest pain. It contains Tirofiban, an antiplatelet that prevents platelets (blood cells) from sticking together to form blood clots. Thus, it is used to prevent blood clots. It also helps blood flow to the heart and prevents heart attack and chest pain. Additionally, it may be used in patients whose heart vessels are dilated with a balloon (percutaneous coronary intervention or PCI). It is intended for use with unfractionated heparin and aspirin.

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Whats That

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Composition :

TIROFIBAN-5MG

Manufacturer/Marketer :

United Biotech Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About TIROBAN 5MG INJECTION

TIROBAN 5MG INJECTION belongs to a class of medicines called 'antiplatelets' (blood thinners) used to prevent blood clots. It helps to prevent heart attack and chest pain. It is intended for use with unfractionated heparin and aspirin. A blood clot is a clump of blood that has changed from a liquid to a gel-like or semisolid state. Blood clots are formed to stop bleeding that occurs due to tissue injury. Though blood clots are useful for stopping bleeding, they are harmful when abnormally formed within blood vessels as they block blood vessels and inhibit blood flow to essential organs such as the brain, heart, or lungs.

TIROBAN 5MG INJECTION contains Tirofiban, a platelet aggregation inhibitor which works by preventing platelets (blood cells) from sticking together to form blood clots. Thus, it prevents blood clot formation.

TIROBAN 5MG INJECTION will be administered by a healthcare professional; do not self-administer. Sometimes, TIROBAN 5MG INJECTION may cause common side effects such as bleeding under the skin at the site of injection or into a muscle causing swelling, bleeding after surgery, invisible blood in stool or urine, headache or feeling sick. Most of these side effects of TIROBAN 5MG INJECTION do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Tirofiban or any other medicines, please tell your doctor. TIROBAN 5MG INJECTION is not recommended for children as safety and effectiveness were not established. If you are a pregnant or breastfeeding woman, inform your doctor before receiving TIROBAN 5MG INJECTION . Avoid alcohol consumption with TIROBAN 5MG INJECTION as it may increase the risk of bleeding in the stomach or intestines. If you have a history of stroke or bleeding internally within the last 30 days, avoid receiving TIROBAN 5MG INJECTION .

Uses of TIROBAN 5MG INJECTION

Prevention of blood clots, heart attack and chest pain

Directions for Use

TIROBAN 5MG INJECTION will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

TIROBAN 5MG INJECTION contains Tirofiban, an antiplatelet which prevents platelets (blood cells) from sticking together to form blood clots. Thus, it is used to prevent blood clots. Also, it helps blood flow to the heart and prevents heart attack and chest pain. Additionally, it may be used in patients whose heart vessels are dilated with a balloon (percutaneous coronary intervention or PCI). It is intended for use with unfractionated heparin and aspirin.

How TIROBAN 5MG INJECTION Works

TIROBAN 5MG INJECTION contains Tirofiban, a platelet aggregation inhibitor which works by preventing platelets (blood cells) from sticking together to form blood clots. Thus, it prevents blood clot formation.

Storage

Store in a cool and dry place away from sunlight

Side Effects of TIROBAN 5MG INJECTION

  • Bleeding under the skin at the site of injection or into a muscle causes swelling
  • Bleeding after surgery
  • Invisible blood in stool or urine
  • Headache
  • Feeling sick

What if I have taken an overdose of TIROBAN 5MG INJECTION

Since TIROBAN 5MG INJECTION is given in a controlled medical setting by a healthcare professional, an overdose is not likely to occur. If you think there has been an overdose or experiencing any adverse events, get medical care right away. In a medical setting, an overdose would be treated quickly.

Drug Warnings

If you are allergic to Tirofiban or any other medicines, please tell your doctor. TIROBAN 5MG INJECTION is not recommended for children as safety and effectiveness were not established. If you are a pregnant or breastfeeding woman, inform your doctor before receiving TIROBAN 5MG INJECTION . Avoid alcohol consumption with TIROBAN 5MG INJECTION as it may increase the risk of bleeding in the stomach or intestines. If you have a history of stroke or bleeding internally within the last 30 days, avoid receiving TIROBAN 5MG INJECTION . If you have had cardiopulmonary resuscitation (CPR), a biopsy, or a procedure to break up kidney stones within the last 2 weeks or have been seriously injured, had a major operation or had an ulcer in the stomach or intestine within the last 3 months, had a recent spinal procedure, have history or symptoms of aortic dissection (splitting of the aorta, main artery), or had a special intravenous line inserted under your collar bone within the last 24 hours, inform your doctor before receiving TIROBAN 5MG INJECTION .

Drug-Drug Interactions

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TirofibanHeparin
Severe
TirofibanEnoxaparin
Severe

Drug-Drug Interactions

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TirofibanHeparin
Severe
How does the drug interact with Tiroban 5mg Injection 100ml:
Taking Tiroban 5mg Injection 100ml with Heparin can increase the risk of bleeding.

How to manage the interaction:
Although there is a possible interaction between Heparin and Tiroban 5mg Injection 100ml, you can take these medicines together if prescribed by a doctor. However, if you have unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
TirofibanEnoxaparin
Severe
How does the drug interact with Tiroban 5mg Injection 100ml:
Combining Tiroban 5mg Injection 100ml with Enoxaparin can increase the risk of bleeding.

How to manage the interaction:
Taking Enoxaparin with Tiroban 5mg Injection 100ml together can result in an interaction, but it can be taken if your doctor has advised it. If you have any of these symptoms, it's important to contact a doctor right away back pain, numbness, constipation, bleeding, bruises, dizziness, lightheaded, red or black stools, severe headache, weakness, or vomiting blood. Do not discontinue any medications without consulting a doctor.
TirofibanRivaroxaban
Severe
How does the drug interact with Tiroban 5mg Injection 100ml:
Co-administration of Tiroban 5mg Injection 100ml and Rivaroxaban can increase the risk of bleeding problems.

How to manage the interaction:
Co-administration of Tiroban 5mg Injection 100ml and Rivaroxaban can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
TirofibanClopidogrel
Severe
How does the drug interact with Tiroban 5mg Injection 100ml:
Taking Clopidogrel with Tiroban 5mg Injection 100ml can make the antiplatelet effects of Tiroban 5mg Injection 100ml stronger.

How to manage the interaction:
There may be a possibility of interaction between Tiroban 5mg Injection 100ml and Clopidogrel, but it can be taken if prescribed by a doctor. Do not discontinue any medications without consulting your doctor.
TirofibanDasatinib
Severe
How does the drug interact with Tiroban 5mg Injection 100ml:
Using dasatinib together with Tiroban 5mg Injection 100ml may increase the risk of bleeding.

How to manage the interaction:
Co-administration of Tiroban 5mg Injection 100ml with Dasatinib can result in an interaction, but it can be taken if a doctor has advised it. You should seek immediate medical attention if you experience any unusual bleeding or bruising or have other signs and symptoms of bleeding such as dizziness; lightheadedness; red or black, tarry stools; coughing up or vomiting fresh or dried blood that looks like coffee grounds; severe headache; and weakness. Do not stop using any medications without a doctor's advice.
TirofibanDalteparin
Severe
How does the drug interact with Tiroban 5mg Injection 100ml:
Combining Tiroban 5mg Injection 100ml with Dalteparin can increase the risk of bleeding.

How to manage the interaction:
Although taking Dalteparin with Tiroban 5mg Injection 100ml may possibly lead to an interaction, they can be taken if a doctor prescribes it. Consult a doctor if you have any symptoms including dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that resembles coffee grounds, severe headache, and weakness. Without consulting a doctor, never stop taking any medication.
TirofibanCangrelor
Severe
How does the drug interact with Tiroban 5mg Injection 100ml:
Co-administration of Tiroban 5mg Injection 100ml with Cangrelor can increase the risk of bleeding.

How to manage the interaction:
Although there is a possible interaction between Tiroban 5mg Injection 100ml and Cangrelor, you can take these medicines together if prescribed by your doctor. However, consult doctor immediately if you experience any unusual bleeding or bruising, or have other signs and symptoms of bleeding such as dizziness; lightheadedness; red or black, tarry stools; coughing up or vomiting fresh or dried blood that looks like coffee grounds; severe headache; and weakness. Do not stop using any medications without a doctor's advice.
TirofibanApixaban
Severe
How does the drug interact with Tiroban 5mg Injection 100ml:
Coadministration of Tiroban 5mg Injection 100ml and Apixaban co-administration may raise the risk of bleeding.

How to manage the interaction:
Even though combining Tiroban 5mg Injection 100ml and Apixaban may cause an interaction, it is still possible to take it if your doctor advises you to. Consult a doctor if you experience symptoms like blood in your urine or stool (or a black stool), severe bruising, prolonged nosebleeds, feeling dizzy or lightheaded, weakness or severe headache, vomiting blood or coughing up blood, heavy menstrual bleeding (in women), difficulty breathing, or chest pain. Without consulting a doctor, never stop taking any medications.
TirofibanFondaparinux
Severe
How does the drug interact with Tiroban 5mg Injection 100ml:
Taking Tiroban 5mg Injection 100ml with Fondaparinux can increase the risk of bleeding.

How to manage the interaction:
Although there is an interaction between Fondaparinux and Tiroban 5mg Injection 100ml, it can be taken if your doctor has advised it. However, if you experience bleeding, severe back pain, dizziness, black or red stools, severe headache, weakness, and vomiting contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
TirofibanIbrutinib
Severe
How does the drug interact with Tiroban 5mg Injection 100ml:
Co-administration of Ibrutinib with Tiroban 5mg Injection 100ml can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Taking Ibrutinib with Tiroban 5mg Injection 100ml together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Avoid making any changes in your diet without first talking to your doctor to avoid medication interactions.
  • Include foods high in antioxidants, such as vegetables, fruits, olive oil, seeds, nuts, cocoa, and red wine, as they may lower the risk of developing blood clots.
  • Adopt an anti-inflammatory diet high in omega-3-rich foods, fruits and vegetables, and vitamin E-rich foods.
  • Drink plenty of fluids as dehydration can thicken blood leading to an increased risk of blood clot formation.
  • Do regular exercise as it helps to dissolve blood clots, especially in obese people.
  • Avoid alcohol consumption as it may increase the risk of bleeding.

Habit Forming

No

Therapeutic Class

ANTICOAGULANT/ANTITHROMBOTIC

TIROBAN 5MG INJECTION Substitute

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Alcohol

Unsafe

You are recommended to avoid the consumption of alcohol with TIROBAN 5MG INJECTION as it may increase the risk of bleeding in the stomach or intestines.

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Pregnancy

Consult your doctor

Limited data is available on the effect of TIROBAN 5MG INJECTION in pregnancy. Hence, if you are pregnant or planning pregnancy, inform your doctor before receiving TIROBAN 5MG INJECTION . Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

Limited data is available on the effect of TIROBAN 5MG INJECTION on breastfeeding mothers. Hence, if you are a nursing mother, inform your doctor before receiving TIROBAN 5MG INJECTION . Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Driving

Not applicable

Due to your disease state, you will not be able to drive or operate machinery while receiving TIROBAN 5MG INJECTION .

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Liver

Caution

TIROBAN 5MG INJECTION is not recommended if you have severe liver disease. Therefore, if you have any liver disorder, inform your doctor before receiving TIROBAN 5MG INJECTION .

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Kidney

Caution

If you have kidney disease/condition, inform your doctor before receiving TIROBAN 5MG INJECTION . The dose may be adjusted in patients with severe kidney failure.

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Children

Unsafe

TIROBAN 5MG INJECTION is not recommended for children as the safety and effectiveness were not established.

FAQs

TIROBAN 5MG INJECTION is used to prevent blood clots, heart attack and chest pain.

TIROBAN 5MG INJECTION contains Tirofiban, a platelet aggregation inhibitor which works by preventing platelets (blood cells) from sticking together to form blood clots. Thus, it prevents blood clot formation.

TIROBAN 5MG INJECTION is not recommended for patients with severe liver disease. Therefore, if you have any liver disorder, inform your doctor before receiving TIROBAN 5MG INJECTION .

Yes, TIROBAN 5MG INJECTION may cause bleeding. If you notice blood in urine or stool or coughing up blood, please inform your doctor immediately, as these might be signs of internal bleeding.

While taking TIROBAN 5MG INJECTION , avoid medications such as NSAIDs (aspirin, ibuprofen), anticoagulants (heparin, warfarin), thrombolytic agents (streptokinase), other antiplatelet medicines (clopidogrel), and SSRIs (citalopram), as they may interact with TIROBAN 5MG INJECTION and cause negative complications. Always inform your doctor about your medication and health history for personalized guidance.

TIROBAN 5MG INJECTION is administered through an intravenous (IV) infusion by a healthcare professional.

You should avoid consuming alcohol while on TIROBAN 5MG INJECTION since it may raise the risk of bleeding in the stomach or intestines.

TIROBAN 5MG INJECTION gets to work quickly, and you may start feeling better within a few hours. As the medication rapidly prevents blood clots, you'll be on the road to recovery in no time. Follow your doctor's instructions and complete the full treatment course to ensure maximum benefits and a speedy return to health.

The common side effects of the TIROBAN 5MG INJECTION may include bleeding under the skin at the site of injection or into a muscle, causing swelling, bleeding after surgery, invisible blood in stool or urine, headache, or feeling sick. Most of these side effects of TIROBAN 5MG INJECTION do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Country of origin

India

Manufacturer/Marketer address

FC/B-1 (Extn.), Mohan Co-operative Industrial Estate Mathura Road, New Delhi - 110 044
Other Info - TIR0005

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