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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Nov 30, 2024 | 3:18 PM IST

Aggritor 5mg Infusion is used to Prevent blood clots, heart attacks, and chest pain. It contains Tirofiban, an antiplatelet that prevents platelets (blood cells) from sticking together to form blood clots. Thus, it is used to prevent blood clots. It also helps blood flow to the heart and prevents heart attack and chest pain. Additionally, it may be used in patients whose heart vessels are dilated with a balloon (percutaneous coronary intervention or PCI). It is intended for use with unfractionated heparin and aspirin.

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Prescription drug

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Prescription drug
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Composition

TIROFIBAN-5MG

Manufacturer/Marketer

Torrent Pharmaceuticals Ltd

Consume Type

PARENTERAL

Return Policy

Not Returnable

for this medicine

About Aggritor 5mg Infusion

Aggritor 5mg Infusion belongs to a class of medicines called 'antiplatelets' (blood thinners) used to prevent blood clots. It helps to prevent heart attack and chest pain. It is intended for use with unfractionated heparin and aspirin. A blood clot is a clump of blood that has changed from a liquid to a gel-like or semisolid state. Blood clots are formed to stop bleeding that occurs due to tissue injury. Though blood clots are useful for stopping bleeding, they are harmful when abnormally formed within blood vessels as they block blood vessels and inhibit blood flow to essential organs such as the brain, heart, or lungs.

Aggritor 5mg Infusion contains Tirofiban, a platelet aggregation inhibitor which works by preventing platelets (blood cells) from sticking together to form blood clots. Thus, it prevents blood clot formation.

Aggritor 5mg Infusion will be administered by a healthcare professional; do not self-administer. Sometimes, Aggritor 5mg Infusion may cause common side effects such as bleeding under the skin at the site of injection or into a muscle causing swelling, bleeding after surgery, invisible blood in stool or urine, headache or feeling sick. Most of these side effects of Aggritor 5mg Infusion do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Tirofiban or any other medicines, please tell your doctor. Aggritor 5mg Infusion is not recommended for children as safety and effectiveness were not established. If you are a pregnant or breastfeeding woman, inform your doctor before receiving Aggritor 5mg Infusion. Avoid alcohol consumption with Aggritor 5mg Infusion as it may increase the risk of bleeding in the stomach or intestines. If you have a history of stroke or bleeding internally within the last 30 days, avoid receiving Aggritor 5mg Infusion.

Uses of Aggritor 5mg Infusion

Prevention of blood clots, heart attack and chest pain

Medicinal Benefits

Aggritor 5mg Infusion contains Tirofiban, an antiplatelet which prevents platelets (blood cells) from sticking together to form blood clots. Thus, it is used to prevent blood clots. Also, it helps blood flow to the heart and prevents heart attack and chest pain. Additionally, it may be used in patients whose heart vessels are dilated with a balloon (percutaneous coronary intervention or PCI). It is intended for use with unfractionated heparin and aspirin.

Directions for Use

Aggritor 5mg Infusion will be administered by a healthcare professional; do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Aggritor 5mg Infusion

  • Bleeding under the skin at the site of injection or into a muscle causes swelling
  • Bleeding after surgery
  • Invisible blood in stool or urine
  • Headache
  • Feeling sick

Drug Warnings

If you are allergic to Tirofiban or any other medicines, please tell your doctor. Aggritor 5mg Infusion is not recommended for children as safety and effectiveness were not established. If you are a pregnant or breastfeeding woman, inform your doctor before receiving Aggritor 5mg Infusion. Avoid alcohol consumption with Aggritor 5mg Infusion as it may increase the risk of bleeding in the stomach or intestines. If you have a history of stroke or bleeding internally within the last 30 days, avoid receiving Aggritor 5mg Infusion. If you have had cardiopulmonary resuscitation (CPR), a biopsy, or a procedure to break up kidney stones within the last 2 weeks or have been seriously injured, had a major operation or had an ulcer in the stomach or intestine within the last 3 months, had a recent spinal procedure, have history or symptoms of aortic dissection (splitting of the aorta, main artery), or had a special intravenous line inserted under your collar bone within the last 24 hours, inform your doctor before receiving Aggritor 5mg Infusion.

Drug Interactions

Drug-Drug Interaction: Inform your doctor if you are taking another blood thinner (warfarin) or are taking or have recently taken other medicines, including those obtained without a prescription.

Drug-Food Interaction: No interactions found.

Drug-Disease Interaction: Avoid receiving Aggritor 5mg Infusion if are bleeding internally, have severe uncontrolled high blood pressure, thrombocytopenia (low blood platelet count), have severe liver disease or have a history of stroke, bleeding in the brain, abnormal blood vessels in the brain or brain tumour. If you have anaemia (lack of blood), liver disorder, heart failure, kidney problems, vasculitis (inflammation of the blood vessels), uncontrolled high blood pressure, pericarditis (inflammation of the lining around your heart), bleeding disorder, cardiogenic shock (very low blood pressure due to a failing heart) or ulcer in the stomach or intestine, inform your doctor before receiving Aggritor 5mg Infusion.

Drug-Drug Interactions Checker List

  • WARFARIN

Habit Forming

No

Diet & Lifestyle Advise

  • Avoid making any changes in your diet without first talking to your doctor to avoid medication interactions.
  • Include foods high in antioxidants, such as vegetables, fruits, olive oil, seeds, nuts, cocoa, and red wine, as they may lower the risk of developing blood clots.
  • Adopt an anti-inflammatory diet high in omega-3-rich foods, fruits and vegetables, and vitamin E-rich foods.
  • Drink plenty of fluids as dehydration can thicken blood leading to an increased risk of blood clot formation.
  • Do regular exercise as it helps to dissolve blood clots, especially in obese people.
  • Avoid alcohol consumption as it may increase the risk of bleeding.

Disease/Condition Glossary

Blood clots: A blood clot is a clump of blood that has changed from a liquid to a gel-like or semisolid state. Blood clots are formed to stop bleeding that occurs due to tissue injury. Though blood clots are useful to stop bleeding, they may be harmful when abnormally formed within blood vessels as they block blood vessels and inhibit blood flow to essential organs such as the brain, heart, or lungs and result in serious conditions. The common risk factors for blood clots are obesity, smoking, cancer, family history of blood clots, aged over 65 years, certain birth control pills, or pregnancy. If you experience chest pressure, sudden shortness of breath, or difficulty in breathing, speaking, or seeing, please consult a doctor immediately, as these might be symptoms of blood clots. Quick medication is advised to reduce the risk of serious conditions due to blood clots.

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Alcohol

Unsafe

You are recommended to avoid the consumption of alcohol with Aggritor 5mg Infusion as it may increase the risk of bleeding in the stomach or intestines.

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Pregnancy

Consult your doctor

Limited data is available on the effect of Aggritor 5mg Infusion in pregnancy. Hence, if you are pregnant or planning pregnancy, inform your doctor before receiving Aggritor 5mg Infusion. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

Limited data is available on the effect of Aggritor 5mg Infusion on breastfeeding mothers. Hence, if you are a nursing mother, inform your doctor before receiving Aggritor 5mg Infusion. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Driving

Not applicable

Due to your disease state, you will not be able to drive or operate machinery while receiving Aggritor 5mg Infusion.

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Liver

Caution

Aggritor 5mg Infusion is not recommended if you have severe liver disease. Therefore, if you have any liver disorder, inform your doctor before receiving Aggritor 5mg Infusion.

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Kidney

Caution

If you have kidney disease/condition, inform your doctor before receiving Aggritor 5mg Infusion. The dose may be adjusted in patients with severe kidney failure.

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Children

Unsafe

Aggritor 5mg Infusion is not recommended for children as the safety and effectiveness were not established.

Country of origin

India
Other Info - AG49940

Author Details

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FAQs

Aggritor 5mg Infusion is used to prevent blood clots, heart attack and chest pain.
Aggritor 5mg Infusion contains Tirofiban, a platelet aggregation inhibitor which works by preventing platelets (blood cells) from sticking together to form blood clots. Thus, it prevents blood clot formation.
Aggritor 5mg Infusion is not recommended for patients with severe liver disease. Therefore, if you have any liver disorder, inform your doctor before receiving Aggritor 5mg Infusion.
Yes, Aggritor 5mg Infusion may cause bleeding. If you notice blood in urine or stool or coughing up blood, please inform your doctor immediately, as these might be signs of internal bleeding.
While taking Aggritor 5mg Infusion, avoid medications such as NSAIDs (aspirin, ibuprofen), anticoagulants (heparin, warfarin), thrombolytic agents (streptokinase), other antiplatelet medicines (clopidogrel), and SSRIs (citalopram), as they may interact with Aggritor 5mg Infusion and cause negative complications. Always inform your doctor about your medication and health history for personalized guidance.
Aggritor 5mg Infusion is administered through an intravenous (IV) infusion by a healthcare professional.
You should avoid consuming alcohol while on Aggritor 5mg Infusion since it may raise the risk of bleeding in the stomach or intestines.
Aggritor 5mg Infusion gets to work quickly, and you may start feeling better within a few hours. As the medication rapidly prevents blood clots, you'll be on the road to recovery in no time. Follow your doctor's instructions and complete the full treatment course to ensure maximum benefits and a speedy return to health.
The common side effects of the Aggritor 5mg Infusion may include bleeding under the skin at the site of injection or into a muscle, causing swelling, bleeding after surgery, invisible blood in stool or urine, headache, or feeling sick. Most of these side effects of Aggritor 5mg Infusion do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

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