Thiokem-D Injection

Thiokem-D Injection is a combination medication primarily used to treat acute musculoskeletal pain and muscle spasms. Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body.

Thiokem-D Injection is a combination of Diclofenac and Thiocolchicoside. Diclofenac is a non-steroidal anti-inflammatory drug (pain killer/NSAID) with analgesic properties. It inhibits cyclo-oxygenase (COX) enzymes and further prevents the formation of chemical messengers, 'prostaglandins' (PGs), that cause pain and swelling at the injured or damaged site. Thiocolchicoside is a muscle relaxant that works on the centres of the spinal cord and brain. This process helps reduce muscle stiffness and improves muscle movements, thus relieving pain due to muscle spasms.

A healthcare professional will administer this medicine. Common side effects of Thiokem-D Injection include headache, stomach upset, constipation, dizziness, drowsiness, diarrhoea, pain, swelling, and redness at the injection site. These side effects are not familiar to everyone and vary individually. However, if the side effects are persistent, please consult your doctor.

Before starting Thiokem-D Injection, inform your doctor if you have any liver, heart or kidney diseases, high blood pressure, diabetes, stomach ulcers, asthma, and auto-immune conditions like systemic lupus erythematosus. Pregnant and breastfeeding women should consult their doctor before using Thiokem-D Injection. Avoid consuming alcohol while undergoing treatment with Thiokem-D Injection. This medicine is not recommended for children and adolescents below 18 years of age as safety has not been established. However, please seek medical advice.

Thiokem-D Injection treats acute musculoskeletal pain and muscle spasms. It contains Diclofenac and Thiocolchicoside. Diclofenac is a non-steroidal anti-inflammatory drug (NSAID) and relieves pain. It inhibits cyclo-oxygenase (COX) enzymes that further prevent the formation of chemical messengers called 'prostaglandins' (PGs). These prostaglandins are produced at injury sites and cause pain and swelling. By blocking the COX enzymes' effect, lesser PGs are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site. Thiocolchicoside is a muscle relaxant that works on the centres of the spinal cord and brain. This process helps reduce muscle stiffness and improves muscle movements, thus relieving pain due to muscle spasms.

• Headache
• Stomach upset
• Constipation
• Dizziness
• Drowsiness
• Diarrhoea
• Pain, swelling, and redness at the injection site 

Inform your doctor if you have any liver, heart or kidney diseases, high blood pressure, diabetes, stomach ulcers, gastrointestinal diseases, asthma, and autoimmune diseases (systemic lupus erythematosus) before being treated with Thiokem-D Injection. Please consult your doctor before starting Thiokem-D Injection if you have high cholesterol, chickenpox, porphyria (rare inherited disorder), hereditary disorders like Lapp lactase deficiency (lactose intolerance), galactose intolerance, glucose-galactose malabsorption (small intestines not being able to absorb and use glucose and galactose), fits, and blood clotting disorders. Do not take any other NSAIDs for pain relief along with Thiokem-D Injection unless prescribed. Stop using Thiokem-D Injection and consult your doctor immediately if you have stomach pain or any signs of bleeding in the intestine or stomach, such as blood in stools. Thiokem-D Injection is not recommended for pregnant and breastfeeding women; hence, please seek medical advice. This medicine may cause dizziness and drowsiness, so drive only if you are alert and focused. Thiokem-D Injection is not recommended in children and adolescents below 18 years as safety and efficacy are not established.

Drug-Drug Interaction: Thiokem-D Injection may interact with anti-diabetics, water pills, blood thinners (warfarin), anti-depressants (lithium), anti-cancer drugs (methotrexate), immunosuppressants (ciclosporin, tacrolimus), medicines used for abortion (mifepristone), pain killers (aspirin), heart-related drugs (digoxin), antibiotics (voriconazole), fits medicines (phenytoin), cholesterol-lowering drugs (cholestyramine, colestipol), and antiretrovirals (zidovudine).

Drug-Food Interaction: Avoid alcohol consumption while using this medicine to avoid the risk of adverse effects.

Drug-Disease Interaction: Before starting Thiokem-D Injection, inform your doctor if you have stomach ulcers, galactose intolerance, glucose-galactose malabsorption, Lapp lactase deficiency, fits, asthma, porphyria, diabetes, high blood pressure, autoimmune diseases, heart, kidney, and liver problems.

• WARFARIN
• LITHIUM
• METHOTREXATE
• CICLOSPORIN
• TACROLIMUS
• MIFEPRISTONE
• ASPIRIN
• DIGOXIN
• VORICONAZOLE
• PHENYTOIN
• CHOLESTYRAMINE
• COLESTIPOL
• ZIDOVUDINE

• Exercising regularly helps in muscle stretching, reducing spasm, tear and sprain incidence. Mild exercises, such as jogging and walking, are helpful for muscle stretching.
• Massages can also be helpful to ease the pain.
• Avoid wearing tight-fitting clothes; wear loose garments for proper blood circulation.
• Rest well and get plenty of sleep.
• Hot or cold therapy can help treat muscle spasms. Apply an ice or hot pack on the muscle for 15-20 minutes.
• Stay hydrated; drink plenty of water.

• Let your doctor know that you are taking Thiokem-D Injection if you are undergoing any medical tests.
• Your doctor may recommend liver function tests to monitor your liver function.

Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body.

Muscular spasms are involuntary muscle contractions that can be unpleasant and uncomfortable. Muscle spasms can occur when the nerve signals that regulate muscle action are disrupted or stopped. Muscle tightness, joint stiffness, atypical posture, trouble moving, and discomfort in afflicted muscles and joints are all symptoms. Muscle spasms can be triggered by fatigue (weakness), stress, excessive heat or cold, illness, and tight clothing. Muscular relaxants and exercise can both be used to treat muscle spasms. Muscle relaxants numb the muscle and help prevent unpleasant spasms. At the same time, exercise aids in muscular stretching, making spasms, tears, and sprains less common.