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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 9, 2024 | 12:36 PM IST
Aquaril TH 2mg/37.5mg Injection is used to treat acute musculoskeletal pain and muscle spasms. It contains Diclofenac and Thiocolchicoside. Diclofenac is a non-steroidal anti-inflammatory drug (pain killer/NSAID) with analgesic properties. It inhibits cyclo-oxygenase (COX) enzymes and further prevents the formation of chemical messengers, 'prostaglandins' (PGs), that cause pain and swelling at the injured or damaged site. Thiocolchicoside is a muscle relaxant that works on the spinal cord and brain centres. This process helps reduce muscle stiffness and improves muscle movements, thus relieving pain due to muscle spasms.
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Manufacturer/Marketer

Merril Pharma Pvt Ltd

Consume Type

PARENTERAL

Return Policy

Not Returnable

for this medicine

About Aquaril TH 2mg/37.5mg Injection

Aquaril TH 2mg/37.5mg Injection is a combination medication primarily used to treat acute musculoskeletal pain and muscle spasms. Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body.

Aquaril TH 2mg/37.5mg Injection is a combination of Diclofenac and Thiocolchicoside. Diclofenac is a non-steroidal anti-inflammatory drug (pain killer/NSAID) with analgesic properties. It inhibits cyclo-oxygenase (COX) enzymes and further prevents the formation of chemical messengers, 'prostaglandins' (PGs), that cause pain and swelling at the injured or damaged site. Thiocolchicoside is a muscle relaxant that works on the centres of the spinal cord and brain. This process helps reduce muscle stiffness and improves muscle movements, thus relieving pain due to muscle spasms.

A healthcare professional will administer this medicine. Common side effects of Aquaril TH 2mg/37.5mg Injection include headache, stomach upset, constipation, dizziness, drowsiness, diarrhoea, pain, swelling, and redness at the injection site. These side effects are not familiar to everyone and vary individually. However, if the side effects are persistent, please consult your doctor.

Before starting Aquaril TH 2mg/37.5mg Injection, inform your doctor if you have any liver, heart or kidney diseases, high blood pressure, diabetes, stomach ulcers, asthma, and auto-immune conditions like systemic lupus erythematosus. Pregnant and breastfeeding women should consult their doctor before using Aquaril TH 2mg/37.5mg Injection. Avoid consuming alcohol while undergoing treatment with Aquaril TH 2mg/37.5mg Injection. This medicine is not recommended for children and adolescents below 18 years of age as safety has not been established. However, please seek medical advice.

Uses of Aquaril TH 2mg/37.5mg Injection

Treatment of Acute musculoskeletal pain and muscle spasms

Medicinal Benefits

Aquaril TH 2mg/37.5mg Injection treats acute musculoskeletal pain and muscle spasms. It contains Diclofenac and Thiocolchicoside. Diclofenac is a non-steroidal anti-inflammatory drug (NSAID) and relieves pain. It inhibits cyclo-oxygenase (COX) enzymes that further prevent the formation of chemical messengers called 'prostaglandins' (PGs). These prostaglandins are produced at injury sites and cause pain and swelling. By blocking the COX enzymes' effect, lesser PGs are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site. Thiocolchicoside is a muscle relaxant that works on the centres of the spinal cord and brain. This process helps reduce muscle stiffness and improves muscle movements, thus relieving pain due to muscle spasms.

Directions for Use

It will be administered by a healthcare professional; do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Aquaril TH 2mg/37.5mg Injection

  • Headache
  • Stomach upset
  • Constipation
  • Dizziness
  • Drowsiness
  • Diarrhoea
  • Pain, swelling, and redness at the injection site 

Drug Warnings

Inform your doctor if you have any liver, heart or kidney diseases, high blood pressure, diabetes, stomach ulcers, gastrointestinal diseases, asthma, and autoimmune diseases (systemic lupus erythematosus) before being treated with Aquaril TH 2mg/37.5mg Injection. Please consult your doctor before starting Aquaril TH 2mg/37.5mg Injection if you have high cholesterol, chickenpox, porphyria (rare inherited disorder), hereditary disorders like Lapp lactase deficiency (lactose intolerance), galactose intolerance, glucose-galactose malabsorption (small intestines not being able to absorb and use glucose and galactose), fits, and blood clotting disorders. Do not take any other NSAIDs for pain relief along with Aquaril TH 2mg/37.5mg Injection unless prescribed. Stop using Aquaril TH 2mg/37.5mg Injection and consult your doctor immediately if you have stomach pain or any signs of bleeding in the intestine or stomach, such as blood in stools. Aquaril TH 2mg/37.5mg Injection is not recommended for pregnant and breastfeeding women; hence, please seek medical advice. This medicine may cause dizziness and drowsiness, so drive only if you are alert and focused. Aquaril TH 2mg/37.5mg Injection is not recommended in children and adolescents below 18 years as safety and efficacy are not established.

Drug Interactions

Drug-Drug Interaction: Aquaril TH 2mg/37.5mg Injection may interact with anti-diabetics, water pills, blood thinners (warfarin), anti-depressants (lithium), anti-cancer drugs (methotrexate), immunosuppressants (ciclosporin, tacrolimus), medicines used for abortion (mifepristone), pain killers (aspirin), heart-related drugs (digoxin), antibiotics (voriconazole), fits medicines (phenytoin), cholesterol-lowering drugs (cholestyramine, colestipol), and antiretrovirals (zidovudine).

Drug-Food Interaction: Avoid alcohol consumption while using this medicine to avoid the risk of adverse effects.

Drug-Disease Interaction: Before starting Aquaril TH 2mg/37.5mg Injection, inform your doctor if you have stomach ulcers, galactose intolerance, glucose-galactose malabsorption, Lapp lactase deficiency, fits, asthma, porphyria, diabetes, high blood pressure, autoimmune diseases, heart, kidney, and liver problems.

Drug-Drug Interactions Checker List

  • WARFARIN
  • LITHIUM
  • METHOTREXATE
  • CICLOSPORIN
  • TACROLIMUS
  • MIFEPRISTONE
  • ASPIRIN
  • DIGOXIN
  • VORICONAZOLE
  • PHENYTOIN
  • CHOLESTYRAMINE
  • COLESTIPOL
  • ZIDOVUDINE

Habit Forming

No

Diet & Lifestyle Advise

  • Exercising regularly helps in muscle stretching, reducing spasm, tear and sprain incidence. Mild exercises, such as jogging and walking, are helpful for muscle stretching.
  • Massages can also be helpful to ease the pain.
  • Avoid wearing tight-fitting clothes; wear loose garments for proper blood circulation.
  • Rest well and get plenty of sleep.
  • Hot or cold therapy can help treat muscle spasms. Apply an ice or hot pack on the muscle for 15-20 minutes.
  • Stay hydrated; drink plenty of water.

Special Advise

  • Let your doctor know that you are taking Aquaril TH 2mg/37.5mg Injection if you are undergoing any medical tests.
  • Your doctor may recommend liver function tests to monitor your liver function.

Disease/Condition Glossary

Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body.

Muscular spasms are involuntary muscle contractions that can be unpleasant and uncomfortable. Muscle spasms can occur when the nerve signals that regulate muscle action are disrupted or stopped. Muscle tightness, joint stiffness, atypical posture, trouble moving, and discomfort in afflicted muscles and joints are all symptoms. Muscle spasms can be triggered by fatigue (weakness), stress, excessive heat or cold, illness, and tight clothing. Muscular relaxants and exercise can both be used to treat muscle spasms. Muscle relaxants numb the muscle and help prevent unpleasant spasms. At the same time, exercise aids in muscular stretching, making spasms, tears, and sprains less common.

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Alcohol

Caution

Please seek medical advice if you have a regular alcohol intake habit before taking Aquaril TH 2mg/37.5mg Injection

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Pregnancy

Unsafe

Aquaril TH 2mg/37.5mg Injection is not recommended during pregnancy as it may harm your developing baby. Please consult your doctor for more information.

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Breast Feeding

Unsafe

Aquaril TH 2mg/37.5mg Injection is not recommended during breastfeeding as it may be excreted in breast milk. Please consult your doctor for more information.

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Driving

Caution

Aquaril TH 2mg/37.5mg Injection may make you feel dizzy and sleepy. Do not drive or operate machinery if you experience dizziness or drowsiness after taking Aquaril TH 2mg/37.5mg Injection.

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Liver

Caution

Aquaril TH 2mg/37.5mg Injection should be used cautiously in patients with liver impairment/liver disease. If you have liver disease, please inform your doctor before receiving this medicine.

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Kidney

Caution

Aquaril TH 2mg/37.5mg Injection should be used cautiously in patients with kidney impairment/liver disease. If you have kidney disease, please inform your doctor before receiving this medicine.

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Children

Unsafe

Aquaril TH 2mg/37.5mg Injection is not recommended for use in children as the safety and efficacy data are not established. Please seek medical advice for more information.

Country of origin

India

Manufacturer/Marketer address

Shop No. 5, Opp. Parmar Mechanic, Jai Hind Street, Tramway Road, Surendra Nagar - 363 002, Gujarat
Other Info - AQ64575

Author Details

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FAQs

Aquaril TH 2mg/37.5mg Injection is used to treat Acute musculoskeletal pain and muscle spasms.
Aquaril TH 2mg/37.5mg Injection contains Diclofenac and Thiocolchicoside. Diclofenac works by blocking the action of certain chemical messengers that cause pain and inflammation at the injured or damaged site. Thiocolchicoside is a muscle relaxant which relieves muscle stiffness due to muscle spasms and improves muscle movements.
Diarrhoea can be a side-effect of Aquaril TH 2mg/37.5mg Injection. Drink enough fluids and eat fibre-rich food if you experience diarrhoea. If you find blood in the stools (tarry stools) or experience excess diarrhoea, consult your doctor. Do not take anti-diarrhoeal medicine on your own.
Using other NSAIDs or painkillers is not advised while using Aquaril TH 2mg/37.5mg Injection. Please seek medical advice for further information.
You are not recommended to take Aquaril TH 2mg/37.5mg Injection with warfarin as simultaneous use of these two medicines may increase the effect of anti-coagulants/blood thinners and cause bleeding risk. Please seek medical advice for more information.

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