Synstim 50 mg Combipack Injection 1's belongs to a class of alkylating agents, also known as chemotherapeutic agents. It is used to treat various cancer conditions such as multiple myeloma ((a type of cancer that develops from cells in the bone marrow called plasma cells), advanced cancer of the ovaries, childhood neuroblastoma (cancer of the nervous system), malignant melanoma (skin cancer) and soft tissue sarcoma. Cancer is a genetic change in which the body's cells divide uncontrollably and spread into surrounding tissues. Synstim 50 mg Combipack Injection 1's is also used to destroy bone marrow and cancer cells in preparation for a bone marrow transplant in people with multiple myeloma.

Synstim 50 mg Combipack Injection 1's contains Melphalan, which reduces the number of abnormal cells your body makes. Thus, it treats cancer efficiently.

Synstim 50 mg Combipack Injection 1's will be administered only in a hospital setting by an experienced healthcare professional. The most common adverse reactions observed in patients treated with Synstim 50 mg Combipack Injection 1's are neutrophil count decreased, white blood cell count decreased, platelet count decreased, lymphocyte count decreased, diarrhoea, fatigue, anaemia, nausea, vomiting and hypokalemia. Most of these side effects do not require medical attention and will resolve gradually. However, you are advised to talk to your doctor if any of these side effects persist or worsen.

Treatment with Synstim 50 mg Combipack Injection 1's is not advised during pregnancy since it may harm the fetus. If you are already pregnant, you should inform your doctor before receiving Synstim 50 mg Combipack Injection 1's. To avoid pregnancy while on treatment with Synstim 50 mg Combipack Injection 1's, you or your partner must use reliable contraceptive precautions. Inform you are doctor if you are breastfeeding.

Synstim 50 mg Combipack Injection 1's is an alkylating medicine, also known as a chemotherapeutic agent, primarily used to treat various cancer conditions such as multiple myeloma (a type of cancer that develops from cells in the bone marrow called plasma cells), advanced cancer of the ovaries, childhood neuroblastoma (cancer of the nervous system), malignant melanoma (skin cancer) and soft tissue sarcoma. Melphalan, present in Synstim 50 mg Combipack Injection 1's, works by reducing the number of abnormal cells produced by your body. As a result, it effectively treats cancer.

• A drop in the number of blood cells and platelets
• Nausea
• Vomiting
• Diarrhoea
• Mouth ulcers
• Diarrhea
• Fatigue
• Anemia
• Hypokalemia (low potassium)

Before taking Synstim 50 mg Combipack Injection 1's inform your doctor if you are pregnant or breastfeeding. If you become pregnant while on treatment with Synstim 50 mg Combipack Injection 1's, inform your doctor. Before taking Synstim 50 mg Combipack Injection 1's, inform your doctor about your medical history and ongoing therapies to rule out potential adverse effects or interactions. Always take Synstim 50 mg Combipack Injection 1's as prescribed by your doctor. It's crucial to take your medication as directed. The dosage of this medicine is based on your condition. Your doctor may adjust your dose during therapy based on the results of the treatment. If you have kidney issues, your doctor will usually give you a lower dose than other adults. Your doctor will determine if you should undergo preventive medication for blood clots in the veins. This applies during the first 5 months of treatment or if you have an elevated risk of developing a blood clot in your veins. The amount of blood cells in your bone marrow may drastically drop if you take Synstim 50 mg Combipack Injection 1's. In addition to raising your chance of getting a serious infection or bleeding, this could result in specific symptoms. Please contact your doctor right away if you encounter any of the following symptoms: abnormal bleeding or bruises; bloody or black, tarry stools; bloody vomit; or vomiting blood or brown material that resembles coffee grounds; fever, sore throat, persistent cough and congestion, or other symptoms of infection. Remember to keep all of your doctor's and the lab's appointments. Before and throughout your treatment, your doctor will order routine laboratory testing to determine whether this medication is having an impact on your blood cells. Synstim 50 mg Combipack Injection 1's may make you more susceptible to getting other cancers. Talk to your doctor to know more about Synstim 50 mg Combipack Injection 1's.

Drug-Drug Interactions: Synstim 50 mg Combipack Injection 1's may interact with cancer medications (e.g. adalimumab), vaccines (e.g. BCG vaccine, influenza virus vaccine), medications used to treat Multiple Sclerosis (e.g. cladribine), schizophrenia medications (e.g. clozapine), medicines used to treat moderate to severe plaque psoriasis (e.g. Deucravacitinib), medicines used to manage and treat autoimmune conditions (e.g. etanercept), antirheumatic drug (e.g. leflunomide).

Drug-Food Interactions: Avoid the consumption of alcoholic beverages.

Drug-Disease Interactions: Synstim 50 mg Combipack Injection 1's may interact with disease conditions, including infections, myelosuppression (bone marrow doesn't make enough blood cells or platelets), pulmonary pneumonitis (an irritating substance causes the tiny air sacs (alveoli) in your lungs to become inflamed)/fibrosis and renal dysfunction.

• ADALIMUMAB
• BCG VACCINE
• INFLUENZA VIRUS VACCINE
• CLADRIBINE
• CLOZAPINE
• DEUCRAVACITINIB
• ETANERCEPT
• LEFLUNOMIDE

• De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
• Performing yoga may also help in improving both physical and mental health.
• Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
• Eat a healthy diet and exercise regularly to maintain proper weight.
• Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs.
• Get optimal sleep; rest well.
• Avoid smoking and alcohol consumption.
• Avoid fast food, fried food, processed meats, refined carbs and added sugars.

When you take Synstim 50 mg Combipack Injection 1's, your doctor will suggest regular blood tests to monitor the count of blood cells.

Cancer: Cancer is a genetic change in which the body's cells divide uncontrollably and spread into surrounding tissues. There are two types of cancer: benign (localized) and metastatic (spread to the whole body). Types of cancer include blood, lung, breast, etc. Cancer growth can be prevented by chemotherapy, radiation, and stem cell therapy.

Multiple myeloma: Multiple myeloma is a type of cancer affecting white blood cells called plasma cells. These cells collect in the bone marrow and divide uncontrollably, leading to kidney and bone damage. Symptoms include bone pain, loss of appetite, fever, and frequent infections. Generally, multiple myeloma cannot be cured, but the signs and symptoms can be reduced greatly or disappear after a period of time.

Ovarian cancer: Ovarian cancer begins in the ovaries (one of a pair of female reproductive glands in which the ova, or eggs, are formed).

Childhood neuroblastoma: Neuroblastoma is a rare type of cancer that occurs in nerve tissue. It usually affects children under the age of five. Fatigue, decreased appetite, and a lump in the chest, neck, or belly are all symptoms. Chemotherapy, surgery, and radiation therapy are all options for treatment.

Malignant Melanoma: Melanoma is a type of skin cancer in which the cancer cells grow in melanocytes. It is mainly caused by harmful UV radiation from the sun. When the cancer cells spread to other parts of the body, it is known as Metastasis. Malignant melanoma is common in fair-skinned and freckled individuals. It results in mole formation, typically on the skin of the face. 

Soft tissue sarcoma: Soft tissue sarcoma is an uncommon type of cancer that begins with cell proliferation in the body's soft tissues. Soft tissue sarcoma can develop in any part of the body. It most commonly occurs in the arms, legs, and belly.