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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Melfalax 50 Injection is used to treat Multiple myeloma, advanced cancer of the ovaries, childhood neuroblastoma (cancer of the nervous system), malignant melanoma (skin cancer) and soft tissue sarcoma. It contains Melphalan, which reduces the number of abnormal cells your body makes. Thus, it treats cancer efficiently. The most common adverse reactions observed in patients treated with this medicine are neutrophil count decreased, white blood cell count decreased, platelet count decreased, lymphocyte count decreased, diarrhoea, fatigue, anaemia, nausea, vomiting and hypokalemia.

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Whats That

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Composition :

MELPHALAN-50MG

Manufacturer/Marketer :

GLS Pharma Ltd

Consume Type :

PARENTERAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Melfalax 50 Injection

Melfalax 50 Injection belongs to a class of alkylating agents, also known as chemotherapeutic agents. It is used to treat various cancer conditions such as multiple myeloma ((a type of cancer that develops from cells in the bone marrow called plasma cells), advanced cancer of the ovaries, childhood neuroblastoma (cancer of the nervous system), malignant melanoma (skin cancer) and soft tissue sarcoma. Cancer is a genetic change in which the body's cells divide uncontrollably and spread into surrounding tissues. Melfalax 50 Injection is also used to destroy bone marrow and cancer cells in preparation for a bone marrow transplant in people with multiple myeloma.

Melfalax 50 Injection contains Melphalan, which reduces the number of abnormal cells your body makes. Thus, it treats cancer efficiently.

Melfalax 50 Injection will be administered only in a hospital setting by an experienced healthcare professional. The most common adverse reactions observed in patients treated with Melfalax 50 Injection are neutrophil count decreased, white blood cell count decreased, platelet count decreased, lymphocyte count decreased, diarrhoea, fatigue, anaemia, nausea, vomiting and hypokalemia. Most of these side effects do not require medical attention and will resolve gradually. However, you are advised to talk to your doctor if any of these side effects persist or worsen.

Treatment with Melfalax 50 Injection is not advised during pregnancy since it may harm the fetus. If you are already pregnant, you should inform your doctor before receiving Melfalax 50 Injection. To avoid pregnancy while on treatment with Melfalax 50 Injection, you or your partner must use reliable contraceptive precautions. Inform you are doctor if you are breastfeeding.

Uses of Melfalax 50 Injection

Treatment of Multiple myeloma, advanced cancer of the ovaries, childhood neuroblastoma (cancer of the nervous system), malignant melanoma (skin cancer) and soft tissue sarcoma

Directions for Use

Melfalax 50 Injection will be given to you by your healthcare professional.

Medicinal Benefits

Melfalax 50 Injection is an alkylating medicine, also known as a chemotherapeutic agent, primarily used to treat various cancer conditions such as multiple myeloma (a type of cancer that develops from cells in the bone marrow called plasma cells), advanced cancer of the ovaries, childhood neuroblastoma (cancer of the nervous system), malignant melanoma (skin cancer) and soft tissue sarcoma. Melphalan, present in Melfalax 50 Injection, works by reducing the number of abnormal cells produced by your body. As a result, it effectively treats cancer.

How Melfalax 50 Injection Works

Melfalax 50 Injection contains Melphalan, which reduces the number of abnormal cells your body makes. Thus, it treats cancer efficiently.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Melfalax 50 Injection

  • A drop in the number of blood cells and platelets
  • Nausea
  • Vomiting
  • Diarrhoea
  • Mouth ulcers
  • Diarrhea
  • Fatigue
  • Anemia
  • Hypokalemia (low potassium)

What if I have taken an overdose of Melfalax 50 Injection

Please do not exceed the recommended dose, as it might cause an overdose. Signs and symptoms of an overdose of Melfalax 50 Injection may include diarrhoea (that is severe or doesn't stop), dizziness, muscle weakness, mental/mood changes (such as confusion), slow/irregular heartbeat, and decreased urination. Seek immediate medical attention if you observe these symptoms or think you might have taken too much. Do this even if there are no signs of discomfort or poisoning.

Drug Warnings

Before taking Melfalax 50 Injection inform your doctor if you are pregnant or breastfeeding. If you become pregnant while on treatment with Melfalax 50 Injection, inform your doctor. Before taking Melfalax 50 Injection, inform your doctor about your medical history and ongoing therapies to rule out potential adverse effects or interactions. Always take Melfalax 50 Injection as prescribed by your doctor. It's crucial to take your medication as directed. The dosage of this medicine is based on your condition. Your doctor may adjust your dose during therapy based on the results of the treatment. If you have kidney issues, your doctor will usually give you a lower dose than other adults. Your doctor will determine if you should undergo preventive medication for blood clots in the veins. This applies during the first 5 months of treatment or if you have an elevated risk of developing a blood clot in your veins. The amount of blood cells in your bone marrow may drastically drop if you take Melfalax 50 Injection. In addition to raising your chance of getting a serious infection or bleeding, this could result in specific symptoms. Please contact your doctor right away if you encounter any of the following symptoms: abnormal bleeding or bruises; bloody or black, tarry stools; bloody vomit; or vomiting blood or brown material that resembles coffee grounds; fever, sore throat, persistent cough and congestion, or other symptoms of infection. Remember to keep all of your doctor's and the lab's appointments. Before and throughout your treatment, your doctor will order routine laboratory testing to determine whether this medication is having an impact on your blood cells. Melfalax 50 Injection may make you more susceptible to getting other cancers. Talk to your doctor to know more about Melfalax 50 Injection.

Drug-Drug Interactions

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MelphalanBCG vaccine
Critical
MelphalanYellow fever vaccine
Critical

Drug-Drug Interactions

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MelphalanBCG vaccine
Critical
How does the drug interact with Melfalax 50 Injection 1's:
Co-administration of the BCG vaccine with Melfalax 50 Injection 1's together can increase the risk or severity of infection or reduces the effectiveness of the vaccine.

How to manage the interaction:
Taking Melfalax 50 Injection 1's with the BCG vaccine is not recommended, but it can be taken if prescribed by the doctor. Do not stop using any medication without consulting your doctor.
MelphalanYellow fever vaccine
Critical
How does the drug interact with Melfalax 50 Injection 1's:
Co-administration of the Yellow fever vaccine with Melfalax 50 Injection 1's can increase the risk or severity of infection or reduces the effectiveness of the vaccine.

How to manage the interaction:
Taking Melfalax 50 Injection 1's with the Yellow fever vaccine is not recommended, but it can be taken if prescribed by the doctor. Do not stop using any medication without consulting your doctor.
MelphalanFilgrastim
Severe
How does the drug interact with Melfalax 50 Injection 1's:
Co-administration of Filgrastim together with Melfalax 50 Injection 1's can reduce the effect of Filgrastim.

How to manage the interaction:
Although taking Filgrastim and Melfalax 50 Injection 1's together can cause an interaction, it can be taken if a doctor has suggested it. Do not discontinue any medications without consulting a doctor.
MelphalanGolimumab
Severe
How does the drug interact with Melfalax 50 Injection 1's:
Co-administration of Melfalax 50 Injection 1's with Golimumab together can increase the risk of infection.

How to manage the interaction:
Co-administration of Melfalax 50 Injection 1's with Golimumab can possibly result in an interaction, but it can be taken if a doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
MelphalanFingolimod
Severe
How does the drug interact with Melfalax 50 Injection 1's:
Co-administration of Fingolimod and Melfalax 50 Injection 1's can increase the risk of infection.

How to manage the interaction:
There may be a possibility of interaction between Melfalax 50 Injection 1's and Fingolimod, but it can be taken if prescribed by a doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
MelphalanThiotepa
Severe
How does the drug interact with Melfalax 50 Injection 1's:
Co-administration of Melfalax 50 Injection 1's with Thiotepa can increase the risk and severity of side effects.

How to manage the interaction:
Although there is a possible interaction between Melfalax 50 Injection 1's and Thiotepa, you can take these medicines together if prescribed by a doctor. If you notice any unusual symptoms or side effects, contact a doctor right away. Do not discontinue any medications without consulting a doctor.
MelphalanVoclosporin
Severe
How does the drug interact with Melfalax 50 Injection 1's:
Co-administration of Melfalax 50 Injection 1's with Voclosporin can increase the seriousness of side effects.

How to manage the interaction:
Taking Melfalax 50 Injection 1's with Voclosporin together can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any signs like infection, fever, chills, diarrhoea, sore throat, muscle aches, difficulty breathing, weight loss, or pain while urinating, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
MelphalanCladribine
Severe
How does the drug interact with Melfalax 50 Injection 1's:
Co-administration of Cladribine with Melfalax 50 Injection 1's together can increase the risk and severity of infection.

How to manage the interaction:
Co-administration of Melfalax 50 Injection 1's with Cladribine can possibly result in an interaction, but it can be taken if a doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
MelphalanNalidixic acid
Severe
How does the drug interact with Melfalax 50 Injection 1's:
Co-administration of Nalidixic acid with Melfalax 50 Injection 1's together can increase the risk or severity of side effects.

How to manage the interaction:
Although taking Melfalax 50 Injection 1's and Nalidixic acid together can evidently cause an interaction, it can be taken if your doctor has suggested it. However contact a doctor immediately, if you experience any symptoms such as easy bruising or bleeding, unusual weakness, nausea, stomach pain, low fever, or loss of appetite. Do not discontinue any medications without consulting a doctor.
MelphalanInfliximab
Severe
How does the drug interact with Melfalax 50 Injection 1's:
Co-administration of Infliximab with Melfalax 50 Injection 1's can increase the serious infection.

How to manage the interaction:
There may be a possibility of interaction between Melfalax 50 Injection 1's and Infliximab, but it can be taken if prescribed by a doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Performing yoga may also help in improving both physical and mental health.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs.
  • Get optimal sleep; rest well.
  • Avoid smoking and alcohol consumption.
  • Avoid fast food, fried food, processed meats, refined carbs and added sugars.

Habit Forming

No

Therapeutic Class

CHEMOTHERAPY

Melfalax 50 Injection Substitute

Substitutes safety advice
  • ALKACEL 50MG INJECTION

    1980.00per tablet
  • MEGVAL 50MG INJECTION

    2568.60per tablet
  • Myelostem 50 Injection 1's

    2160.00per tablet
  • Alphalan 50 mg Injection 1's

    1890.00per tablet
  • Alkacel PGF 50 mg Injection 1's

    2255.00per tablet
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Alcohol

Caution

Avoid alcohol consumption while on treatment with Melfalax 50 Injection.

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Pregnancy

Caution

Melfalax 50 Injection should not be used during pregnancy. So, inform your doctor if you are pregnant or suspect pregnancy. You or your partner must use a reliable form of contraception to prevent pregnancy while taking these medications.

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Breast Feeding

Caution

If you are breastfeeding, inform your doctor. You should not breastfeed while on treatment with Melfalax 50 Injection.

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Driving

Caution

It is unknown whether Melfalax 50 Injection alters the ability to drive, so do not drive or operate machinery if you experience any symptoms affecting your ability to concentrate and react.

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Liver

Caution

If you have a pre-existing or a history of liver disease, inform your doctor before taking Melfalax 50 Injection.

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Kidney

Caution

If you have a pre-existing or a history of kidney disease, inform your doctor before taking Melfalax 50 Injection. Your doctor may titrate the dose if required based on your condition.

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Children

Caution

Melfalax 50 Injection is only not recommended for use in children as the safety and effectiveness have not been established.

FAQs

Melfalax 50 Injection is used to treat Multiple myeloma, advanced cancer of the ovaries, childhood neuroblastoma (cancer of the nervous system), malignant melanoma (skin cancer) and soft tissue sarcoma.
Melfalax 50 Injection contains Melphalan, which works by reducing the number of abnormal cells your body makes. Thus, it treats cancer efficiently.
While taking Melfalax 50 Injection, make sure to attend all of your doctor's appointments to ensure the therapy is effective. Blood tests and weight checks must be monitored on a regular basis. Both men and women should utilize an effective method of contraception while taking Melfalax 50 Injection.
Melphalan can cause a significant decrease in the number of blood cells and platelets. Your doctor may suggest laboratory tests before and during the treatment.

Country of origin

INDIA

Manufacturer/Marketer address

Wockhardt Towers, Bandra Kurla Complex, Bandra (East), Mumbai 400051, Maharashtra, India
Other Info - MEL0139

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Keep Refrigerated. Do not freeze.

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