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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Nov 10, 2024 | 7:18 PM IST
Sizosure 40 Tablet 10's is used to treat schizophrenia and bipolar disorder. It contains Lurasidone which works by blocking neurotransmitters and helps regulate mood, thoughts and behaviour. In some cases, this medicine may cause side effects such as nausea, vomiting, sleepiness, weight gain, indigestion, dry mouth, and restlessness. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Synonym :

LURASIDONE HYDROCHLORIDE

Composition :

LURASIDONE-40MG

Manufacturer/Marketer :

Ikon Pharmachem

Consume Type :

ORAL

Return Policy :

Not Returnable

About Sizosure 40 Tablet 10's

Sizosure 40 Tablet 10's used in the treatment of schizophrenia (affects a person's ability to feel, think and behave clearly) and bipolar depression (mood swings). Schizophrenia is a mental condition in which the person may feel, hear or see things that are not there, believe things that are not true, or feel unusually suspicious or confused. Bipolar disorder is characterized by manic episodes in which a person experiences extreme mood swings (variance in thinking) and frequent mood and behaviour changes. 

Sizosure 40 Tablet 10's contains ‘lurasidone’, which is an antipsychotic drug. It acts by blocking a hormone (dopamine) present in the brain responsible for developing symptoms of schizophrenia and bipolar disorder. Sizosure 40 Tablet 10's also blocks other neurotransmitters in the brain, such as serotonin. By blocking both, Sizosure 40 Tablet 10's helps to control the brain's activity and decrease the symptoms of schizophrenia and bipolar disease.

Take Sizosure 40 Tablet 10's as prescribed by your doctor. You are advised to take Sizosure 40 Tablet 10's for as long as your doctor has prescribed it for you, depending on your medical conditions. You may experience nausea, vomiting, sleepiness, weight gain, indigestion, dryness in the mouth, akathisia (inability to stay still), stomach discomfort, anxiety, upper abdominal pain, restlessness, agitation (nervous excitement), insomnia (difficulty in sleeping) and increased saliva production. Most of these side effects of Sizosure 40 Tablet 10's do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Sizosure 40 Tablet 10's should not be taken in conditions like if you are allergic to lurasidone or any other ingredients present in it. Before taking Sizosure 40 Tablet 10's, inform your doctor if you have problems associated with the liver, kidney or heart and low blood pressure. It is not recommended for use in children under 13 years of age. Before taking Sizosure 40 Tablet 10's inform your doctor if you are older than 65 years of age as it causes more side effects. Tell your doctor if you are pregnant or breastfeeding. Sizosure 40 Tablet 10's causes drowsiness and dizziness. Do not drive unless you are alert.

Uses of Sizosure 40 Tablet 10's

Treatment of Schizophrenia, Bipolar disorder

Medicinal Benefits

Sizosure 40 Tablet 10's is used to treat certain mood /mental diseases like schizophrenia and depression related to bipolar disorder. Sizosure 40 Tablet 10's helps you to feel less nervous, think more clearly and take part in daily life. It may also help to reduce hallucinations (seeing/hearing things that are not there). It alters brain function and improves mood, thinking ability, and social behaviour. It reduces the development of symptoms in patients with schizophrenia, bipolar disorder or other mood disorders. 

Side Effects of Sizosure 40 Tablet 10's

  • Drowsiness
  • Weight gain
  • Tremors, muscle stiffness, slow muscle movement
  • Feeling restless or unable to sit still
  • Nausea, vomiting
  • Runny nose
  • Sleep problems (insomnia)
  • Dry mouth
  • Abdominal discomfort
  • Agitation

Directions for Use

Take Sizosure 40 Tablet 10's with or without food. Sizosure 40 Tablet 10's should be swallowed as a whole with a glass of water; do not chew or crush the tablet. You are advised to take Sizosure 40 Tablet 10's for as long as your doctor has prescribed it for you, depending on your medical condition.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

It is advisable to you not take Sizosure 40 Tablet 10's if you are allergic to lurasidone or any ingredients present in it. Before taking Sizosure 40 Tablet 10's, inform your doctor if you have low blood pressure, stroke, liver problems, seizures, diabetes, dementia (memory loss), alcohol or drug abuse, sleep apnea (a sleep disorder) and urinary retention. Inform your doctor if you have epilepsy/fits, an increase in your weight, history of blood clots before taking Sizosure 40 Tablet 10's. Tell your doctor immediately if you develop suicidal thoughts, or your depression worsens after taking Sizosure 40 Tablet 10's. There is a greater chance of death in senior adults who take Sizosure 40 Tablet 10's for mental problems caused by dementia (thinking and suicidal symptoms). Most of the deaths were related to infection or heart disease. Avoid drinking alcohol while taking Sizosure 40 Tablet 10's as it may worsen the side effects. Tell your doctor if you are pregnant or breastfeeding. Sizosure 40 Tablet 10's causes drowsiness and dizziness. Do not drive unless you are alert.

Therapeutic Class

ANTIPSYCHOTICS

Drug-Drug Interactions

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LurasidonePosaconazole
Critical
LurasidoneVoriconazole
Critical

Drug-Food Interactions

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LURASIDONE-40MGGrapefruit and Grapefruit Juice
Severe

Diet & Lifestyle Advise

  • Do not take grapefruit or grapefruit juice while using Sizosure 40 Tablet 10's as it may alter the effects of the medicine.
  • Avoid intense exercise as it is harder for the body to cool down when it gets very hot. So, drink plenty of fluids and avoid going out in hot weather.
  • Do not take alcohol as it increases drowsiness and also worsens the disease condition. 
  • Eat healthily and keep a check on your weight regularly.

Habit Forming

No

What if I have taken an overdose of Sizosure 40 Tablet 10's

Take Sizosure 40 Tablet 10's only as prescribed by the doctor. Do not exceed the recommended dose, as it might cause an overdose. If you suspect you have taken an overdose, seek immediate medical attention.
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Alcohol

Unsafe

Avoid consuming alcohol while on treatment with Sizosure 40 Tablet 10's as it may increase the risk of side effects.

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Pregnancy

Caution

Sizosure 40 Tablet 10's is not recommended for use in pregnancy. Hence, if you are pregnant, inform your doctor before taking Sizosure 40 Tablet 10's. Your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

It is not known if Sizosure 40 Tablet 10's passes into the breastmilk. If you are breastfeeding, consult your doctor before taking Sizosure 40 Tablet 10's, your doctor will prescribe this medicine if the benefits outweigh the risks.

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Driving

Caution

Sizosure 40 Tablet 10's may cause dizziness. So, it is not recommended to drive or operate heavy machinery after taking Sizosure 40 Tablet 10's.

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Liver

Caution

Sizosure 40 Tablet 10's should be used with caution in patients with liver disease. If you have liver disease, inform your doctor before taking Sizosure 40 Tablet 10's. Your doctor may adjust the dose based on your condition.

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Kidney

Caution

Sizosure 40 Tablet 10's should be used with caution in patients with kidney disease. If you have kidney disease, inform your doctor before taking Sizosure 40 Tablet 10's. Your doctor may adjust the dose based on your condition.

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Children

Unsafe

Sizosure 40 Tablet 10's is not recommended for use in children under 13 years.

Country of origin

India

Manufacturer/Marketer address

Ikon Pharmachem
Other Info - SIZ0091

Author Details

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FAQs

Sizosure 40 Tablet 10's is used in the treatment of schizophrenia (affects a person's ability to feel, think and behave clearly) and bipolar depression (mood swings). It helps you to feel less nervous, think more clearly and take part in daily life.
Sizosure 40 Tablet 10's may cause an increase in blood glucose (sugar) levels. So, regular monitoring of blood sugar levels is advised while taking Sizosure 40 Tablet 10's. Diabetes patients should consult a doctor before taking Sizosure 40 Tablet 10's.
Weight gain is a common side effect of Sizosure 40 Tablet 10's, although not everyone is affected. If you experience weight gain on taking Sizosure 40 Tablet 10's, inform your doctor. Eating a healthy diet and frequent exercise can help you maintain your weight.
Alcohol should be avoided while taking Sizosure 40 Tablet 10's since taking both together may lead to severe side effects. You should not drink grapefruit juice while on Sizosure 40 Tablet 10's as it affects the way it works.
Sizosure 40 Tablet 10's may raise the risk of death in older persons who suffer from memory loss, perplexity, or have lost touch with reality. It is critical to understand that Sizosure 40 Tablet 10's may cause suicidal behaviour or thoughts in certain children, adolescents, and young adults during the first few months of treatment and when the dose is adjusted.
Dry mouth could be a side-effect of Sizosure 40 Tablet 10's. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly and chewing sugar-free gum/candy might help in stimulating saliva and thereby prevents drying of the mouth.
Sizosure 40 Tablet 10's is an antipsychotic drug that works by blocking a hormone (dopamine) present in the brain responsible for developing symptoms of schizophrenia (a serious mental illness affecting thoughts, feelings, and behaviours) and bipolar disorder (a mental illness that causes mood swings, energy fluctuations, and concentration issues). It also blocks other neurotransmitters in the brain, such as serotonin. By blocking both dopamine and serotonin, Sizosure 40 Tablet 10's helps to control brain activity and decreasesthe symptoms of schizophrenia and bipolar disorder.
The common side effects of Sizosure 40 Tablet 10's include nausea, vomiting, weight gain, indigestion, sleepiness, dryness in the mouth, increased saliva production, akathisia (inability to stay still), anxiety, upper abdominal pain, restlessness, agitation (nervous excitement), and insomnia (difficulty in sleeping). Most of these side effects of Sizosure 40 Tablet 10's do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
No, Sizosure 40 Tablet 10's should not be used during pregnancy unless prescribed by the doctor. Taking Sizosure 40 Tablet 10's in the later months of pregnancy may lead to extrapyramidal (uncontrolled body movements or muscle stiffness in the baby) or withdrawal symptoms after birth such as muscle stiffness, weakness, shakiness, sleepiness, breathing problems, agitation, and difficulty feeding. If you are pregnant or planning for pregnancy, please consult your doctor before taking Sizosure 40 Tablet 10's. The doctor will prescribe Sizosure 40 Tablet 10's only if the benefits outweigh the risks and will monitor the baby closely after birth.
Close monitoring for the emergence or worsening of suicidal behaviour and thoughts is recommended in patients taking Sizosure 40 Tablet 10's. Sizosure 40 Tablet 10's may increase blood sugar levels in diabetic patients, especially in those with schizophrenia. So, you should immediately inform your doctor if you experience symptoms such as increased thirst, frequent urination, fatigue, or increased appetite. It may also lead to weight gain, increase prolactin, cholesterol, and triglyceride levels, and decrease white blood cell count. Hence, regular monitoring of blood sugar levels, blood cell counts, hormone levels (prolactin), and cholesterol levels is advised while taking Sizosure 40 Tablet 10's. 
Sizosure 40 Tablet 10's should be taken with food for better absorption of the medicine. It should be swallowed whole with a glass of water; do not chew or crush the tablet.
Sizosure 40 Tablet 10's may take several weeks or longer before you experience any improvement in your symptoms. Continue to take Sizosure 40 Tablet 10's even if you feel well, and do not stop taking it without talking to your doctor.
Yes, Sizosure 40 Tablet 10's can cause dizziness, fainting, and lightheadedness when you stand up too quickly after lying down. This is more likely to happen when you first start taking Sizosure 40 Tablet 10's or if your dose changes. To help prevent this problem, rise slowly from the bed and allow your feet to rest on the floor for a few minutes before standing up.

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