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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Sandimmun Neoral 25mg Capsule is used to prevent organ rejection after a transplant. Also, it helps to reduce the pain/inflammation in rheumatoid arthritis conditions and in the treatment of psoriasis. It contains Cyclosporine, which works by suppressing the body's immune system. Thereby, prevents organ rejection. It helps decrease pain and swelling, thus providing relief from the symptoms of rheumatoid arthritis. In some cases, it may cause headache, vomiting nausea, high blood pressure, loss of appetite (feeling unwell and upset stomach), and diarrhoea. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Composition :

CYCLOSPORINE-25MG

Manufacturer/Marketer :

Novartis India Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Sandimmun Neoral 25mg Capsule

Sandimmun Neoral 25mg Capsule belongs to the class of medicines called 'immunosuppressants' used to prevent organ rejection after a transplant. Also, it helps to reduce the pain/inflammation in rheumatoid arthritis conditions and in the treatment of psoriasis. Organ rejection occurs when patient’s immune system recognizes the donor organ as foreign and tries to eliminate it.

Sandimmun Neoral 25mg Capsule contains 'cyclosporine' which works by suppressing the body's immune system. Thereby, prevents organ rejection. It helps decrease pain and swelling, thus providing relief from the symptoms of rheumatoid arthritis.

Take Sandimmun Neoral 25mg Capsule as prescribed. You are advised to take Sandimmun Neoral 25mg Capsule for as long as your doctor has prescribed it for you depending on your medical conditions. In some cases, Sandimmun Neoral 25mg Capsule may cause headache, vomiting nausea, high blood pressure, loss of appetite (feeling unwell and upset stomach), and diarrhoea. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Before taking Sandimmun Neoral 25mg Capsule inform your doctor if you have any allergy, kidney disease, uncontrolled high blood pressure, or any type of cancer. Consult your doctor before taking Sandimmun Neoral 25mg Capsule if you are pregnant or breastfeeding. Sandimmun Neoral 25mg Capsule increases the risk of infections and skin cancer. Therefore, stay cautious and avoid prolonged exposure to sunlight. Inform your doctor about your health condition and medicines you are taking to rule out any unpleasant side effects.

Uses of Sandimmun Neoral 25mg Capsule

Prevent organ rejection, Rheumatoid arthritis, psoriasis (a skin disease that causes itchy and dry patches).

Directions for Use

Swallow Sandimmun Neoral 25mg Capsule as a whole with a glass of water; do not break or chew the tablet/capsule.

Medicinal Benefits

Sandimmun Neoral 25mg Capsule belongs to the class of medicines called 'immunosuppressant' used to prevent organ rejection after a transplant. Also, it helps to reduce the pain/inflammation in rheumatoid arthritis and is used in the treatment of severe cases of skin diseases such as eczema, psoriasis and atopic dermatitis, nephrotic syndrome (kidney disease), and eye problems such as endogenous uveitis and Behçet's uveitis. Cyclosporine works by suppressing the body's immune system. Thereby, prevents organ rejection. Also, it reduces the function of the cells that cause inflammation, especially in the joint tissues. Thereby, decreasing pain, inflammation, slowing down the joint damage and disease progression over time.

How Sandimmun Neoral 25mg Capsule Works

Sandimmun Neoral 25mg Capsule contains 'cyclosporine' which works by suppressing the body's immune system. Thereby, prevents organ rejection. It helps decrease pain and swelling, thus providing relief from the symptoms of rheumatoid arthritis.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Sandimmun Neoral 25mg Capsule

  • Headache
  • Vomiting
  • Nausea
  • High blood pressure
  • Loss of appetite
  • Diarrhea

What if I have taken an overdose of Sandimmun Neoral 25mg Capsule

Do not take more than the prescribed dose of Sandimmun Neoral 25mg Capsule as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Do not take Sandimmun Neoral 25mg Capsule if you are allergic to any of the components. Let your doctor know before using Sandimmun Neoral 25mg Capsule if you have liver or kidney problems, high blood pressure, low levels of magnesium, and high levels of potassium. Sandimmun Neoral 25mg Capsule may make you more susceptible to infections; consult your doctor if you develop any signs of severe conditions such as fever, sore throat, breathlessness, jaundice, unexplained bleeding, or bruising. Before taking Sandimmun Neoral 25mg Capsule inform your doctor if you have any type of cancer. Do not take Sandimmun Neoral 25mg Capsule if you are pregnant or planning for pregnancy. Sandimmun Neoral 25mg Capsule should not be taken by breastfeeding mothers as it passes into breast milk. Inform your doctor about your health condition and medicines to rule out any unpleasant side effects.

Drug-Drug Interactions

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CiclosporinCidofovir
Critical
CiclosporinSimvastatin
Critical

Drug-Drug Interactions

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CiclosporinCidofovir
Critical
How does the drug interact with Sandimmun Neoral 25mg Capsule 5's:
Taking cyclosporine with cidofovir can increase the risk of kidney problems.

How to manage the interaction:
Taking Sandimmun Neoral 25mg Capsule 5's with Cidofovir is not recommended, but can be taken be together if prescribed by a doctor. However, if you experience nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, contact the doctor immediately. Do not discontinue any medications without consulting a doctor
CiclosporinSimvastatin
Critical
How does the drug interact with Sandimmun Neoral 25mg Capsule 5's:
Combining Sandimmun Neoral 25mg Capsule 5's and Simvastatin can increase the blood levels and effects of Simvastatin. This can increase the risk of side effects such as liver damage and rhabdomyolysis(involves the breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking Sandimmun Neoral 25mg Capsule 5's and Simvastatin together is not recommended as it can lead to an interaction, but it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, or weakness, fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of hunger, weakness, nausea, vomiting, and yellowing of the skin or eyes, contact the doctor immediately. Do not discontinue any medications without consulting your doctor.
CiclosporinBosentan
Critical
How does the drug interact with Sandimmun Neoral 25mg Capsule 5's:
When Bosentan is taken with Cyclosporine, it may increase the risk of side effects.

How to manage the interaction:
Taking Sandimmun Neoral 25mg Capsule 5's with Bosentan is not recommended, but it can be taken if prescribed by the doctor. However, if you experience any symptoms like severe headache, nausea, or an increased heart rate, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
CiclosporinBaricitinib
Critical
How does the drug interact with Sandimmun Neoral 25mg Capsule 5's:
Co-administration of Baricitinib with Cyclosporine can increase the risk of infections as well as some cancers.

How to manage the interaction:
Taking Sandimmun Neoral 25mg Capsule 5's with Baricitinib is not recommended as it can cause an interaction, but it can be taken together if prescribed by a doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
CiclosporinPitavastatin
Critical
How does the drug interact with Sandimmun Neoral 25mg Capsule 5's:
Coadministration of pitavastatin with Sandimmun Neoral 25mg Capsule 5's may significantly increase the blood levels of pitavastatin which can increase the risk of side effects such as liver problems and rhabdomyolysis(involves the breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking Pitavastatin with Sandimmun Neoral 25mg Capsule 5's is not recommended, as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms like unexpected bruising or bleeding, skin rash, itching, tiredness, nausea, vomiting, yellowing of the skin or eyes, unexplained muscular pain, tenderness, or weakness, fever, dark urine, chills, joint pain, or swelling, consult a doctor. Do not discontinue any medications without a doctor's advice.
CiclosporinRitonavir
Severe
How does the drug interact with Sandimmun Neoral 25mg Capsule 5's:
Taking Sandimmun Neoral 25mg Capsule 5's with ritonavir may significantly increases the blood levels of Sandimmun Neoral 25mg Capsule 5's.

How to manage the interaction:
Taking ritonavir with Sandimmun Neoral 25mg Capsule 5's together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience nausea, vomiting, loose stools, abdominal pain, dizziness, weakness, headache, fits, shaking, fever, sore throat, unusual bruising or bleeding, and increased or decreased urination, contact a doctor. Do not stop using any medications without talking to a doctor.
CiclosporinCladribine
Severe
How does the drug interact with Sandimmun Neoral 25mg Capsule 5's:
Using cladribine together with Sandimmun Neoral 25mg Capsule 5's may increase the risk of infections.

How to manage the interaction:
Although taking cladribine and Sandimmun Neoral 25mg Capsule 5's together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, contact a doctor immediately if you experience any symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without a doctor's advice.
CiclosporinIohexol
Severe
How does the drug interact with Sandimmun Neoral 25mg Capsule 5's:
Coadministration of iohexol with Sandimmun Neoral 25mg Capsule 5's may increases the risk of kidney problems.

How to manage the interaction:
Although there is a possible interaction between iohexol and Sandimmun Neoral 25mg Capsule 5's, they can be taken together if your doctor has prescribed them. However, contact your doctor immediately if experience any symptoms such as nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or irregular heart rhythm. Do not stop using any medications without talking to a doctor.
CiclosporinZalcitabine
Severe
How does the drug interact with Sandimmun Neoral 25mg Capsule 5's:
Co-administration of zalcitabine with Sandimmun Neoral 25mg Capsule 5's may significantly decrease the effect of zalcitabine.

How to manage the interaction:
Although there is a possible interaction between Zalcitabine and Sandimmun Neoral 25mg Capsule 5's, you can take these medicines together if prescribed by your doctor. Do not discontinue any medications without consulting a doctor.
CiclosporinAdefovir dipivoxil
Severe
How does the drug interact with Sandimmun Neoral 25mg Capsule 5's:
Coadministration of adefovir dipivoxil with Sandimmun Neoral 25mg Capsule 5's may significantly increase the negative effect of kidneys.

How to manage the interaction:
Although there is a possible interaction between adefovir dipivoxil and Sandimmun Neoral 25mg Capsule 5's, they can be taken together if your doctor has prescribed them. However, contact your doctor if experience any symptoms such as nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or irregular heart rhythm, contact a doctor immediately. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat foods rich in quercetin (a flavonoid) such as apples, cherries, broccoli, spinach, and blueberries.

  • Consuming food rich in probiotics helps in developing the ing immune system against allergies.

  • Limit intake of food that might trigger allergies such as dairy products, soy, eggs, and nuts.

  • Avoid consumption of foods with excess sugar as flare-up inflammation.

  • Include fruits, vegetables, whole grains, healthy fats and fish in your diet.

  • Reducing stress and maintaining a regular sleep pattern would be helpful.

  • Avoid getting in contact with harsh soaps, detergents, and rough fabrics.

Habit Forming

No

Therapeutic Class

IMMUNOSUPPRESSANTS

Sandimmun Neoral 25mg Capsule Substitute

Substitutes safety advice
  • Panimun Bioral 25 mg Capsule 6's

    25.88per tablet
  • Psorid 25 Capsule 5's

    26.46per tablet
  • Arpimune ME 25 Capsule 5's

    22.32per tablet
  • Cyclophil ME-25 Capsule 5's

    by AYUR

    26.46per tablet
  • Grafotas-25mg Softgel Capsule 5's

    23.58per tablet
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Alcohol

Caution

You are recommended to avoid alcohol consumption while taking Sandimmun Neoral 25mg Capsule. It could lead to increased dizziness.

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Pregnancy

Caution

Sandimmun Neoral 25mg Capsule belongs to pregnancy category C. Consult your doctor before taking Sandimmun Neoral 25mg Capsule if you are pregnant or planning for pregnancy.

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Breast Feeding

Unsafe

Sandimmun Neoral 25mg Capsule passes into breast milk. Avoid breastfeeding while taking Sandimmun Neoral 25mg Capsule.

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Driving

Caution

Sandimmun Neoral 25mg Capsule may cause dizziness. Drive or operate machinery only if you are alert.

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Liver

Caution

Dose adjustment may be needed. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Sandimmun Neoral 25mg Capsule is not recommended for children as efficacy and safety have not been established.

FAQs

Sandimmun Neoral 25mg Capsule is used to prevent organ rejection after a transplant. Also, it helps to reduce the pain/inflammation in rheumatoid arthritis conditions and in the treatment of psoriasis.
Sandimmun Neoral 25mg Capsule acts as an immunosuppressant, which helps in reducing inflammation and prevents joint stiffness, thereby provides relief from rheumatoid arthritis.
If you miss a dose of Sandimmun Neoral 25mg Capsule, take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and take the scheduled dose instead.
Diarrhoea might be a side effect of Sandimmun Neoral 25mg Capsule. Drink lots of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience severe diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.
Yes, the use of Sandimmun Neoral 25mg Capsule may cause abnormal facial and body hair growth as a common side effect. Please consult your doctor if you have any concerns.
Sandimmun Neoral 25mg Capsule is known to suppress the immune system. As a result, it increases the risk of infections and developing cancers, especially of the skin. Therefore, avoid prolonged exposure to sunlight by wearing suitable protective clothing and use sunscreen regularly.
Sandimmun Neoral 25mg Capsule may cause high blood pressure. Therefore, consult the doctor before taking Sandimmun Neoral 25mg Capsule if you have high blood pressure.
No, Sandimmun Neoral 25mg Capsule is not a steroid. It is an immunosuppressant.
Sandimmun Neoral 25mg Capsule may cause weight gain. Follow a healthy diet and exercise regularly to maintain proper weight. Consult your doctor if you have any concerns.
Sandimmun Neoral 25mg Capsule may cause fatigue. Eat a healthy diet, get regular exercise, manage stress, improve sleep habits, and quit smoking. Doing these may help cope with fatigue.
Yes, your doctor will recommend certain tests to check your body’s response to Sandimmun Neoral 25mg Capsule.
Sandimmun Neoral 25mg Capsule may cause side effects like headache, vomiting nausea, high blood pressure, loss of appetite (feeling unwell and upset stomach), and diarrhoea. Talk to your doctor if you experience these side effects persistently.
Sandimmun Neoral 25mg Capsule should be swallowed as a whole with water; do not crush or chew it. Take the medicine at the same time each day, and maintain the same amount of time between doses and meals every day.
You are advised to take Sandimmun Neoral 25mg Capsule for the duration prescribed by the doctor. The duration of treatment will depend upon your condition and response to the treatment.

Country of origin

Switzerland

Manufacturer/Marketer address

Sandoz House, Shiv Sagar Estate, Worli Mumbai -400 018, India
Other Info - SAN0036

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