Grafotas-25mg Softgel Capsule belongs to the class of medicines called 'immunosuppressants' used to prevent organ rejection after a transplant. Also, it helps to reduce the pain/inflammation in rheumatoid arthritis conditions and in the treatment of psoriasis. Organ rejection occurs when patient’s immune system recognizes the donor organ as foreign and tries to eliminate it.

Grafotas-25mg Softgel Capsule contains 'cyclosporine' which works by suppressing the body's immune system. Thereby, prevents organ rejection. It helps decrease pain and swelling, thus providing relief from the symptoms of rheumatoid arthritis.

Take Grafotas-25mg Softgel Capsule as prescribed. You are advised to take Grafotas-25mg Softgel Capsule for as long as your doctor has prescribed it for you depending on your medical conditions. In some cases, Grafotas-25mg Softgel Capsule may cause headache, vomiting nausea, high blood pressure, loss of appetite (feeling unwell and upset stomach), and diarrhoea. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Before taking Grafotas-25mg Softgel Capsule inform your doctor if you have any allergy, kidney disease, uncontrolled high blood pressure, or any type of cancer. Consult your doctor before taking Grafotas-25mg Softgel Capsule if you are pregnant or breastfeeding. Grafotas-25mg Softgel Capsule increases the risk of infections and skin cancer. Therefore, stay cautious and avoid prolonged exposure to sunlight. Inform your doctor about your health condition and medicines you are taking to rule out any unpleasant side effects.

Grafotas-25mg Softgel Capsule belongs to the class of medicines called 'immunosuppressant' used to prevent organ rejection after a transplant. Also, it helps to reduce the pain/inflammation in rheumatoid arthritis and is used in the treatment of severe cases of skin diseases such as eczema, psoriasis and atopic dermatitis, nephrotic syndrome (kidney disease), and eye problems such as endogenous uveitis and Behçet's uveitis. Cyclosporine works by suppressing the body's immune system. Thereby, prevents organ rejection. Also, it reduces the function of the cells that cause inflammation, especially in the joint tissues. Thereby, decreasing pain, inflammation, slowing down the joint damage and disease progression over time.

• Headache
• Vomiting
• Nausea
• High blood pressure
• Loss of appetite
• Diarrhea

Do not take Grafotas-25mg Softgel Capsule if you are allergic to any of the components. Let your doctor know before using Grafotas-25mg Softgel Capsule if you have liver or kidney problems, high blood pressure, low levels of magnesium, and high levels of potassium. Grafotas-25mg Softgel Capsule may make you more susceptible to infections; consult your doctor if you develop any signs of severe conditions such as fever, sore throat, breathlessness, jaundice, unexplained bleeding, or bruising. Before taking Grafotas-25mg Softgel Capsule inform your doctor if you have any type of cancer. Do not take Grafotas-25mg Softgel Capsule if you are pregnant or planning for pregnancy. Grafotas-25mg Softgel Capsule should not be taken by breastfeeding mothers as it passes into breast milk. Inform your doctor about your health condition and medicines to rule out any unpleasant side effects.

Drug-Drug Interaction: Grafotas-25mg Softgel Capsule may have interaction with other immunosuppressant medicines (tacrolimus), anti-gout (thiopurine), water pills/diuretics (amiloride, spironolactone), blood pressure-lowering pills (aliskiren), cholesterol-lowering pills (atorvastatin, pitavastatin, simvastatin). antibiotics (such as erythromycin or azithromycin), antifungals (voriconazole, itraconazole), medicines used for heart problems or high blood pressure (diltiazem, verapamil, amiodarone), used to treat menstrual problems (danazol), medicines used to treat gout (allopurinol), used to treat hepatitis C (colchicine, telaprevir).

Drug-Food Interaction:  Avoid grapefruit or grapefruit juice while taking Grafotas-25mg Softgel Capsule.

Drug-Disease Interaction: Grafotas-25mg Softgel Capsule may cause interactions with disease conditions such as high blood pressure, liver, and kidney disease.

• TACROLIMUS
• AMILORIDE
• SPIRONOLACTONE
• ALISKIREN
• ATORVASTATIN
• PITAVASTATIN
• SIMVASTATIN
• ERYTHROMYCIN
• AZITHROMYCIN
• VORICONAZOLE
• ITRACONAZOLE
• DILTIAZEM
• VERAPAMIL
• DANAZOL
• ALLOPURINOL
• COLCHICINE
• TELAPREVIR

• Eat foods rich in quercetin (a flavonoid) such as apples, cherries, broccoli, spinach, and blueberries.

• Consuming food rich in probiotics helps in developing the ing immune system against allergies.

• Limit intake of food that might trigger allergies such as dairy products, soy, eggs, and nuts.

• Avoid consumption of foods with excess sugar as flare-up inflammation.

• Include fruits, vegetables, whole grains, healthy fats and fish in your diet.

• Reducing stress and maintaining a regular sleep pattern would be helpful.

• Avoid getting in contact with harsh soaps, detergents, and rough fabrics.

Organ transplant rejection: When you get a new organ transplanted to your body, your body recognizes it as a foreign element, tries to attack and reject it because it is not originally part of your body. So, immunosuppressant drugs like cyclosporine are given to such patients to suppress the immune system, thereby preventing an attack on a newly transplanted organ. 

Rheumatoid arthritis: It is an autoimmune disease (the body's immune system attacks its tissue) that leads to joint pain and damage. Symptoms of rheumatoid arthritis include pain, inflammation of joints, difficulty moving, and swelling.

Psoriasis: It is a long-lasting, inflammatory skin illness. It is not infectious but has a tendency to run in families. It causes itchy and red patches on the skin.