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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 11, 2024 | 2:34 PM IST
Cyclophil ME-25 Capsule is used to prevent organ rejection after a transplant. Also, it helps to reduce the pain/inflammation in rheumatoid arthritis conditions and in the treatment of psoriasis. It contains Cyclosporine, which works by suppressing the body's immune system. Thereby, prevents organ rejection. It helps decrease pain and swelling, thus providing relief from the symptoms of rheumatoid arthritis. In some cases, it may cause headache, vomiting nausea, high blood pressure, loss of appetite (feeling unwell and upset stomach), and diarrhoea. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Prescription drug

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Prescription drug
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Manufacturer/Marketer

Biocon Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Cyclophil ME-25 Capsule

Cyclophil ME-25 Capsule belongs to the class of medicines called 'immunosuppressants' used to prevent organ rejection after a transplant. Also, it helps to reduce the pain/inflammation in rheumatoid arthritis conditions and in the treatment of psoriasis. Organ rejection occurs when patient’s immune system recognizes the donor organ as foreign and tries to eliminate it.

Cyclophil ME-25 Capsule contains 'cyclosporine' which works by suppressing the body's immune system. Thereby, prevents organ rejection. It helps decrease pain and swelling, thus providing relief from the symptoms of rheumatoid arthritis.

Take Cyclophil ME-25 Capsule as prescribed. You are advised to take Cyclophil ME-25 Capsule for as long as your doctor has prescribed it for you depending on your medical conditions. In some cases, Cyclophil ME-25 Capsule may cause headache, vomiting nausea, high blood pressure, loss of appetite (feeling unwell and upset stomach), and diarrhoea. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Before taking Cyclophil ME-25 Capsule inform your doctor if you have any allergy, kidney disease, uncontrolled high blood pressure, or any type of cancer. Consult your doctor before taking Cyclophil ME-25 Capsule if you are pregnant or breastfeeding. Cyclophil ME-25 Capsule increases the risk of infections and skin cancer. Therefore, stay cautious and avoid prolonged exposure to sunlight. Inform your doctor about your health condition and medicines you are taking to rule out any unpleasant side effects.

Uses of Cyclophil ME-25 Capsule

Prevent organ rejection, Rheumatoid arthritis, psoriasis (a skin disease that causes itchy and dry patches).

Medicinal Benefits

Cyclophil ME-25 Capsule belongs to the class of medicines called 'immunosuppressant' used to prevent organ rejection after a transplant. Also, it helps to reduce the pain/inflammation in rheumatoid arthritis and is used in the treatment of severe cases of skin diseases such as eczema, psoriasis and atopic dermatitis, nephrotic syndrome (kidney disease), and eye problems such as endogenous uveitis and Behçet's uveitis. Cyclosporine works by suppressing the body's immune system. Thereby, prevents organ rejection. Also, it reduces the function of the cells that cause inflammation, especially in the joint tissues. Thereby, decreasing pain, inflammation, slowing down the joint damage and disease progression over time.

Directions for Use

Swallow Cyclophil ME-25 Capsule as a whole with a glass of water; do not break or chew the tablet/capsule.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Cyclophil ME-25 Capsule

  • Headache
  • Vomiting
  • Nausea
  • High blood pressure
  • Loss of appetite
  • Diarrhea

Drug Warnings

Do not take Cyclophil ME-25 Capsule if you are allergic to any of the components. Let your doctor know before using Cyclophil ME-25 Capsule if you have liver or kidney problems, high blood pressure, low levels of magnesium, and high levels of potassium. Cyclophil ME-25 Capsule may make you more susceptible to infections; consult your doctor if you develop any signs of severe conditions such as fever, sore throat, breathlessness, jaundice, unexplained bleeding, or bruising. Before taking Cyclophil ME-25 Capsule inform your doctor if you have any type of cancer. Do not take Cyclophil ME-25 Capsule if you are pregnant or planning for pregnancy. Cyclophil ME-25 Capsule should not be taken by breastfeeding mothers as it passes into breast milk. Inform your doctor about your health condition and medicines to rule out any unpleasant side effects.

Drug Interactions

Drug-Drug Interaction: Cyclophil ME-25 Capsule may have interaction with other immunosuppressant medicines (tacrolimus), anti-gout (thiopurine), water pills/diuretics (amiloride, spironolactone), blood pressure-lowering pills (aliskiren), cholesterol-lowering pills (atorvastatin, pitavastatin, simvastatin). antibiotics (such as erythromycin or azithromycin), antifungals (voriconazole, itraconazole), medicines used for heart problems or high blood pressure (diltiazem, verapamil, amiodarone), used to treat menstrual problems (danazol), medicines used to treat gout (allopurinol), used to treat hepatitis C (colchicine, telaprevir).

Drug-Food Interaction:  Avoid grapefruit or grapefruit juice while taking Cyclophil ME-25 Capsule.

Drug-Disease Interaction: Cyclophil ME-25 Capsule may cause interactions with disease conditions such as high blood pressure, liver, and kidney disease.

Drug-Drug Interactions Checker List

  • TACROLIMUS
  • AMILORIDE
  • SPIRONOLACTONE
  • ALISKIREN
  • ATORVASTATIN
  • PITAVASTATIN
  • SIMVASTATIN
  • ERYTHROMYCIN
  • AZITHROMYCIN
  • VORICONAZOLE
  • ITRACONAZOLE
  • DILTIAZEM
  • VERAPAMIL
  • DANAZOL
  • ALLOPURINOL
  • COLCHICINE
  • TELAPREVIR

Habit Forming

No

Diet & Lifestyle Advise

  • Eat foods rich in quercetin (a flavonoid) such as apples, cherries, broccoli, spinach, and blueberries.

  • Consuming food rich in probiotics helps in developing the ing immune system against allergies.

  • Limit intake of food that might trigger allergies such as dairy products, soy, eggs, and nuts.

  • Avoid consumption of foods with excess sugar as flare-up inflammation.

  • Include fruits, vegetables, whole grains, healthy fats and fish in your diet.

  • Reducing stress and maintaining a regular sleep pattern would be helpful.

  • Avoid getting in contact with harsh soaps, detergents, and rough fabrics.

Disease/Condition Glossary

Organ transplant rejection: When you get a new organ transplanted to your body, your body recognizes it as a foreign element, tries to attack and reject it because it is not originally part of your body. So, immunosuppressant drugs like cyclosporine are given to such patients to suppress the immune system, thereby preventing an attack on a newly transplanted organ. 

Rheumatoid arthritis: It is an autoimmune disease (the body's immune system attacks its tissue) that leads to joint pain and damage. Symptoms of rheumatoid arthritis include pain, inflammation of joints, difficulty moving, and swelling.

Psoriasis: It is a long-lasting, inflammatory skin illness. It is not infectious but has a tendency to run in families. It causes itchy and red patches on the skin.

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Alcohol

Caution

You are recommended to avoid alcohol consumption while taking Cyclophil ME-25 Capsule. It could lead to increased dizziness.

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Pregnancy

Caution

Cyclophil ME-25 Capsule belongs to pregnancy category C. Consult your doctor before taking Cyclophil ME-25 Capsule if you are pregnant or planning for pregnancy.

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Breast Feeding

Unsafe

Cyclophil ME-25 Capsule passes into breast milk. Avoid breastfeeding while taking Cyclophil ME-25 Capsule.

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Driving

Caution

Cyclophil ME-25 Capsule may cause dizziness. Drive or operate machinery only if you are alert.

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Liver

Caution

Dose adjustment may be needed. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Cyclophil ME-25 Capsule is not recommended for children as efficacy and safety have not been established.

Country of origin

INDIA

Manufacturer/Marketer address

20th KM, Hosur Road, Electronic City, Bangalore, India - 560 100
Other Info - CYC0053

Author Details

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FAQs

Cyclophil ME-25 Capsule is used to prevent organ rejection after a transplant. Also, it helps to reduce the pain/inflammation in rheumatoid arthritis conditions and in the treatment of psoriasis.
Cyclophil ME-25 Capsule acts as an immunosuppressant, which helps in reducing inflammation and prevents joint stiffness, thereby provides relief from rheumatoid arthritis.
If you miss a dose of Cyclophil ME-25 Capsule, take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and take the scheduled dose instead.
Diarrhoea might be a side effect of Cyclophil ME-25 Capsule. Drink lots of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience severe diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.
Yes, the use of Cyclophil ME-25 Capsule may cause abnormal facial and body hair growth as a common side effect. Please consult your doctor if you have any concerns.
Cyclophil ME-25 Capsule is known to suppress the immune system. As a result, it increases the risk of infections and developing cancers, especially of the skin. Therefore, avoid prolonged exposure to sunlight by wearing suitable protective clothing and use sunscreen regularly.
Cyclophil ME-25 Capsule may cause high blood pressure. Therefore, consult the doctor before taking Cyclophil ME-25 Capsule if you have high blood pressure.
No, Cyclophil ME-25 Capsule is not a steroid. It is an immunosuppressant.
Cyclophil ME-25 Capsule may cause weight gain. Follow a healthy diet and exercise regularly to maintain proper weight. Consult your doctor if you have any concerns.
Cyclophil ME-25 Capsule may cause fatigue. Eat a healthy diet, get regular exercise, manage stress, improve sleep habits, and quit smoking. Doing these may help cope with fatigue.
Yes, your doctor will recommend certain tests to check your body’s response to Cyclophil ME-25 Capsule.
Cyclophil ME-25 Capsule may cause side effects like headache, vomiting nausea, high blood pressure, loss of appetite (feeling unwell and upset stomach), and diarrhoea. Talk to your doctor if you experience these side effects persistently.
Cyclophil ME-25 Capsule should be swallowed as a whole with water; do not crush or chew it. Take the medicine at the same time each day, and maintain the same amount of time between doses and meals every day.
You are advised to take Cyclophil ME-25 Capsule for the duration prescribed by the doctor. The duration of treatment will depend upon your condition and response to the treatment.

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