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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 9, 2024 | 12:40 PM IST
Renulaz 500SR Tablet 10's is used alone or with other medicines to treat angina pectoris. It helps prevent any further attack of angina by making the heart work more efficiently, and it is used as an add-on to existing treatment in patients whose disease is not adequately controlled by other medicines for angina pectoris, such as beta-blockers or calcium antagonists, or in patients who cannot take these medicines. In some cases, it may cause side effects such as constipation, dizziness, headache, or feeling sick. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Prescription drug

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Composition

RANOLAZINE-500MG

Manufacturer/Marketer

Maxford Healthcare

Consume Type

ORAL

Return Policy

Not Returnable

for this medicine

About Renulaz 500SR Tablet 10's

Renulaz 500SR Tablet 10's is used alone or with other medicines to treat angina pectoris. Angina pectoris is discomfort in the chest or chest pain, which generally occurs due to coronary artery disease (CAD) when an adequate amount of oxygen and blood is not reaching the heart and its muscles. It can also be due to the blockage of the heart's arteries. It helps prevent any further attack of angina by making the heart work more efficiently, and it is used as an add-on to existing treatment in patients whose disease is not adequately controlled by other medicines for angina pectoris, such as beta-blockers or calcium antagonists, or in patients who cannot take these medicines.

The active substance in Renulaz 500SR Tablet 10's is Ranolazine, which reduces sodium ions flow into the heart muscle cells. This interferes with the activity of special channels on the cell surface called 'sodium-dependent calcium channels, through which calcium ions normally enter the cells. This reduces the number of calcium ions that enter the cells. Calcium ions normally cause the heart muscle to contract. By reducing the flow of calcium into the cells, Renulaz 500SR Tablet 10's is thought to help the heart relax, improving blood flow to the heart muscle and relieving the symptoms of angina pectoris.

Your doctor will tell you how to take the Renulaz 500SR Tablet 10's based on your medical condition. You may sometimes experience constipation, dizziness, headache, or feeling sick. Most of these side effects of Renulaz 500SR Tablet 10's do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Do not consume Renulaz 500SR Tablet 10's if you are allergic to any component in this medicine. Renulaz 500SR Tablet 10's should not be stopped even if you feel better for the best results, as it prevents any future harm. If you stop taking the Renulaz 500SR Tablet 10's on your own, your chest pain can come back in more severe form. If you plan to get pregnant or are pregnant or breastfeeding, please consult your doctor to avoid any unwanted harm to the baby. Some lifestyle modifications are important for best results when taking Renulaz 500SR Tablet 10's, like smoking cessation, decreasing alcohol intake, eating well, regular exercise, and managing stress. Renulaz 500SR Tablet 10's should be taken with caution if you have any liver or kidney problems. Also, inform your doctor if you are taking other medications to avoid unwanted side effects or contraindications.

Uses of Renulaz 500SR Tablet 10's

Treatment of Angina Pectoris.

Medicinal Benefits

Renulaz 500SR Tablet 10's is prescribed for treating angina. Renulaz 500SR Tablet 10's is an anti-anginal medication used to treat angina pectoris. It reduces sodium ions' flow into the heart muscle cells. This interferes with the activity of special channels on the cell surface called ‘sodium-dependent calcium channels’ through which calcium ions normally enter the cells. This reduces the number of calcium ions that enter the cells. Calcium ions normally cause the heart muscle to contract. By reducing the flow of calcium into the cells, Renulaz 500SR Tablet 10's is thought to help the heart relax, improving blood flow to the heart muscle and relieving the symptoms of angina pectoris.

Directions for Use

Swallow Renulaz 500SR Tablet 10's as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Renulaz 500SR Tablet 10's

  • Constipation
  • Dizziness
  • Headache
  • Feeling sick

Drug Warnings

Renulaz 500SR Tablet 10's should be taken with caution in liver/kidney disease, are pregnant, plan to become pregnant, or are breastfeeding, history of heart disease. Also, grapefruit juice should be avoided while taking Renulaz 500SR Tablet 10's. As a precautionary measure, junk food items from outside and stick to freshly prepared home-cooked meals for a speedy recovery. Do regular exercise to avoid the feeling of heaviness in the abdomen.

Drug Interactions

 Drug-Drug Interactions: Renulaz 500SR Tablet 10's is known to contra-indicate in certain medicines to treat bacterial infections (clarithromycin, telithromycin), lipid-lowering drugs (simvastatin, atorvastatin), fungal infections (itraconazole, ketoconazole, voriconazole, posaconazole), HIV infection (protease inhibitors), depression (nefazodone), antipsychotic medications (haloperidol), or heart rhythm disorders (quinidine, dofetilide, or sotalol).

Drug-Food Interactions: Renulaz 500SR Tablet 10's may interact with other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Also, grapefruit juice should be avoided while taking Renulaz 500SR Tablet 10's.

Drug-Disease Interactions: Caution should be exercised if used in patients with severe hepatic impairment, renal disease, long QT interval, or using other QT- prolonging drugs.

Drug-Drug Interactions Checker List

  • CLARITHROMYCIN
  • QUINIDINE
  • DOFETILIDE
  • SOTALOL
  • KETOCONAZOLE
  • ITRACONAZOLE

Habit Forming

No

Diet & Lifestyle Advise

  • Maintain a healthy lifestyle by exercising regularly, maintaining weight, and eating a healthy diet.

  • If you suffer from kidney or liver disease, please inform your doctor before taking the Renulaz 500SR Tablet 10's.
  • Alcohol consumption along with Renulaz 500SR Tablet 10's should be avoided as it may cause excessive drowsiness and increase muscle pain.
  • As a precautionary measure, junk food items from outside and stick to freshly prepared home-cooked meals for a speedy recovery.

Disease/Condition Glossary

Angina pectoris: Angina pectoris is discomfort in the chest or chest pain that generally occurs due to coronary artery disease (CAD) when an adequate amount of oxygen and blood is not reaching the heart and its muscles. It can also be due to the blockage of the heart's arteries. It helps prevent any further attack of angina by making the heart work more efficiently, but it does not stop an acute attack of angina pectoris.

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Alcohol

Safe if prescribed

Renulaz 500SR Tablet 10's does not have any reported interaction; hence, if you experience any difficulty, discuss with your doctor.

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Pregnancy

Unsafe

Renulaz 500SR Tablet 10's should not be used when pregnancy unless necessary. So, inform your doctor if you are pregnant or suspect pregnancy. Your doctor will weigh the benefits and potential risks before prescribing Renulaz 500SR Tablet 10's.

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Breast Feeding

Unsafe

Renulaz 500SR Tablet 10's should not be used in nursing mothers. Please consult the doctor if you have any concerns regarding this.

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Driving

Safe if prescribed

Renulaz 500SR Tablet 10's does not have any reported interaction; hence, in case you experience any difficulty, discuss with your doctor.

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Liver

Caution

Renulaz 500SR Tablet 10's to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Renulaz 500SR Tablet 10's to be taken with caution, especially if you have a history of kidney diseases/conditions. The dose may have to be adjusted by your doctor.

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Children

Caution

Renulaz 500SR Tablet 10's is not recommended for children below the age of 18. The safety and effectiveness of Renulaz 500SR Tablet 10's have not been established in children due to limited testing of this drug on children by competent authorities worldwide.

Country of origin

India

Manufacturer/Marketer address

405/406, Zee Nayak Building, Mahatma Gandhi Rd, Vile Parle, E, Maharashtra 400057
Other Info - REN0528

Author Details

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FAQs

Renulaz 500SR Tablet 10's is used alone or with other medicines to treat angina pectoris.
The active substance in Renulaz 500SR Tablet 10's is Ranolazine, which reduces sodium ions flow into the heart muscle cells. This interferes with the activity of special channels on the cell surface called 'sodium-dependent calcium channels through which calcium ions normally enter the cells. This reduces the number of calcium ions that enter the cells. Calcium ions normally cause the heart muscle to contract. By reducing the flow of calcium into the cells, Renulaz 500SR Tablet 10's is thought to help the heart to relax, improving blood flow to the heart muscle and relieving the symptoms of angina pectoris.
No, Renulaz 500SR Tablet 10's does not stop acute attacks (sudden attacks) of angina, but Renulaz 500SR Tablet 10's helps prevent a new attack.
No, alcohol should not be taken with Renulaz 500SR Tablet 10's as it may lead to unwanted side effects and increase angina attacks.
Yes, smoking (tobacco) decreases the efficacy of Renulaz 500SR Tablet 10's, especially when taken for angina (chest pain), so it should be avoided while taking Renulaz 500SR Tablet 10's.
Yes, Renulaz 500SR Tablet 10's can cause an upset stomach when taken empty stomach. So, to avoid it, Renulaz 500SR Tablet 10's should be taken with a meal for best results.
Yes, Renulaz 500SR Tablet 10's can cause drowsiness. If you feel excessively sleepy, please consult your doctor for better advice.
Some major side effects include a rapid, pounding, or irregular heartbeat, difficulty breathing, and fainting. If you encounter any of these symptoms, contact your doctor immediately.
Do not take more than the prescribed dose of Renulaz 500SR Tablet 10's as it may cause overdose. The symptoms of overdose include nausea, vomiting, confusion, dizziness, double vision, fainting, difficulty speaking, uncontrollable shaking of a part of the body, hallucinations and burning, pain, numbness, or tingling in any part of the body. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.
Renulaz 500SR Tablet 10's may increase the blood levels and effects of metoprolol. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your doctor if your condition changes or you experience increased side effects.
Renulaz 500SR Tablet 10's might raise metformin levels, increasing the risk of lactic acidosis. If you are prescribed ranolazine while taking metformin, discuss it with a healthcare physician. They may offer a lesser dose of metformin as a safer alternative.
You can take it if prescribed by the doctor. However, limit simvastatin to 20 mg once daily in individuals taking any dose of Renulaz 500SR Tablet 10's.

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