apollo
0
Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Renulaz 500SR Tablet 10's is used alone or with other medicines to treat angina pectoris. It helps prevent any further attack of angina by making the heart work more efficiently, and it is used as an add-on to existing treatment in patients whose disease is not adequately controlled by other medicines for angina pectoris, such as beta-blockers or calcium antagonists, or in patients who cannot take these medicines. In some cases, it may cause side effects such as constipation, dizziness, headache, or feeling sick. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
Read more
rxMedicinePrescription drug

Whats That

tooltip
Consult Doctor

Composition :

RANOLAZINE-500MG

Manufacturer/Marketer :

Maxford Healthcare

Consume Type :

ORAL

Return Policy :

Not Returnable

About Renulaz 500SR Tablet 10's

Renulaz 500SR Tablet 10's is used alone or with other medicines to treat angina pectoris. Angina pectoris is discomfort in the chest or chest pain, which generally occurs due to coronary artery disease (CAD) when an adequate amount of oxygen and blood is not reaching the heart and its muscles. It can also be due to the blockage of the heart's arteries. It helps prevent any further attack of angina by making the heart work more efficiently, and it is used as an add-on to existing treatment in patients whose disease is not adequately controlled by other medicines for angina pectoris, such as beta-blockers or calcium antagonists, or in patients who cannot take these medicines.

The active substance in Renulaz 500SR Tablet 10's is Ranolazine, which reduces sodium ions flow into the heart muscle cells. This interferes with the activity of special channels on the cell surface called 'sodium-dependent calcium channels, through which calcium ions normally enter the cells. This reduces the number of calcium ions that enter the cells. Calcium ions normally cause the heart muscle to contract. By reducing the flow of calcium into the cells, Renulaz 500SR Tablet 10's is thought to help the heart relax, improving blood flow to the heart muscle and relieving the symptoms of angina pectoris.

Your doctor will tell you how to take the Renulaz 500SR Tablet 10's based on your medical condition. You may sometimes experience constipation, dizziness, headache, or feeling sick. Most of these side effects of Renulaz 500SR Tablet 10's do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Do not consume Renulaz 500SR Tablet 10's if you are allergic to any component in this medicine. Renulaz 500SR Tablet 10's should not be stopped even if you feel better for the best results, as it prevents any future harm. If you stop taking the Renulaz 500SR Tablet 10's on your own, your chest pain can come back in more severe form. If you plan to get pregnant or are pregnant or breastfeeding, please consult your doctor to avoid any unwanted harm to the baby. Some lifestyle modifications are important for best results when taking Renulaz 500SR Tablet 10's, like smoking cessation, decreasing alcohol intake, eating well, regular exercise, and managing stress. Renulaz 500SR Tablet 10's should be taken with caution if you have any liver or kidney problems. Also, inform your doctor if you are taking other medications to avoid unwanted side effects or contraindications.

Uses of Renulaz 500SR Tablet 10's

Treatment of Angina Pectoris.

Directions for Use

Swallow Renulaz 500SR Tablet 10's as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Renulaz 500SR Tablet 10's is prescribed for treating angina. Renulaz 500SR Tablet 10's is an anti-anginal medication used to treat angina pectoris. It reduces sodium ions' flow into the heart muscle cells. This interferes with the activity of special channels on the cell surface called ‘sodium-dependent calcium channels’ through which calcium ions normally enter the cells. This reduces the number of calcium ions that enter the cells. Calcium ions normally cause the heart muscle to contract. By reducing the flow of calcium into the cells, Renulaz 500SR Tablet 10's is thought to help the heart relax, improving blood flow to the heart muscle and relieving the symptoms of angina pectoris.

How Renulaz 500SR Tablet 10's Works

The active substance in Renulaz 500SR Tablet 10's is Ranolazine, which reduces sodium ions flow into the heart muscle cells. This interferes with the activity of special channels on the cell surface called 'sodium-dependent calcium channels, through which calcium ions normally enter the cells. This reduces the number of calcium ions that enter the cells. Calcium ions normally cause the heart muscle to contract. By reducing the flow of calcium into the cells, Renulaz 500SR Tablet 10's is thought to help the heart relax, improving blood flow to the heart muscle and relieving the symptoms of angina pectoris.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Renulaz 500SR Tablet 10's

  • Constipation
  • Dizziness
  • Headache
  • Feeling sick

What if I have taken an overdose of Renulaz 500SR Tablet 10's

Do not take more than the prescribed dose of Renulaz 500SR Tablet 10's as it may cause overdose. The symptoms of overdose include nausea, vomiting, confusion, dizziness, double vision, fainting, difficulty speaking, uncontrollable shaking of a part of the body, hallucinations and burning, pain, numbness, or tingling in any part of the body. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Renulaz 500SR Tablet 10's should be taken with caution in liver/kidney disease, are pregnant, plan to become pregnant, or are breastfeeding, history of heart disease. Also, grapefruit juice should be avoided while taking Renulaz 500SR Tablet 10's. As a precautionary measure, junk food items from outside and stick to freshly prepared home-cooked meals for a speedy recovery. Do regular exercise to avoid the feeling of heaviness in the abdomen.

Drug-Drug Interactions

verifiedApollotooltip
RanolazineVoriconazole
Critical
RanolazineRifapentine
Critical

Drug-Drug Interactions

Login/Sign Up

RanolazineVoriconazole
Critical
How does the drug interact with RENULAZ 500SR 10TAB:
Co-administration of RENULAZ 500SR 10TAB together with Voriconazole may significantly increase the blood levels and effects of RENULAZ 500SR 10TAB.

How to manage the interaction:
Taking RENULAZ 500SR 10TAB with Voriconazole together can result in an interaction, but it can be taken if a doctor has advised it. Consult a doctor if you experience dizziness, or fast or pounding heartbeats. Do not discontinue any medications without consulting a doctor.
RanolazineRifapentine
Critical
How does the drug interact with RENULAZ 500SR 10TAB:
When RENULAZ 500SR 10TAB is taken with Rifapentine, may significantly reduce the blood levels of RENULAZ 500SR 10TAB.

How to manage the interaction:
Taking RENULAZ 500SR 10TAB with Rifapentine together can possibly result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
RanolazineThioridazine
Critical
How does the drug interact with RENULAZ 500SR 10TAB:
When Thioridazine is taken with RENULAZ 500SR 10TAB, may significantly increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking RENULAZ 500SR 10TAB with Thioridazine together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, contact a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.
RanolazinePhenobarbital
Critical
How does the drug interact with RENULAZ 500SR 10TAB:
When RENULAZ 500SR 10TAB is taken with Phenobarbital, may significantly reduce the blood levels of RENULAZ 500SR 10TAB, which may make the medication ineffective or less effective.

How to manage the interaction:
Taking Phenobarbital with RENULAZ 500SR 10TAB can lead to an interaction, consult a doctor before taking it. They can be taken together if advised by a doctor. However, contact a doctor if you experience any symptoms. Do not stop taking any medications without consulting a doctor.
RanolazineEfavirenz
Critical
How does the drug interact with RENULAZ 500SR 10TAB:
When Efavirenz is taken with RENULAZ 500SR 10TAB, it can lower the levels of RENULAZ 500SR 10TAB.

How to manage the interaction:
Taking RENULAZ 500SR 10TAB with Efavirenz is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medication without consulting a doctor.
RanolazineNafcillin
Critical
How does the drug interact with RENULAZ 500SR 10TAB:
When Nafcillin is taken with RENULAZ 500SR 10TAB, may significantly reduce the blood levels of RENULAZ 500SR 10TAB, which may make the medication ineffective or less effective.

How to manage the interaction:
Taking Nafcillin with RENULAZ 500SR 10TAB can lead to an interaction, please consult a doctor before taking it. They can be taken together if advised by a doctor. Do not stop taking any medications without consulting a doctor.
RanolazineClarithromycin
Critical
How does the drug interact with RENULAZ 500SR 10TAB:
When RENULAZ 500SR 10TAB and Clarithromycin are taken together, significantly increases the blood levels and effects of RENULAZ 500SR 10TAB.

How to manage the interaction:
Co-administration of Clarithromycin and Ranozaline can lead to an interaction, it can be taken if advised by a doctor. Do not stop using any medications without a doctor's advice.
RanolazinePrimidone
Critical
How does the drug interact with RENULAZ 500SR 10TAB:
Coadministration of RENULAZ 500SR 10TAB with primidone can reduce the blood levels and effects of RENULAZ 500SR 10TAB.

How to manage the interaction:
Although there is an interaction between Primidone and RENULAZ 500SR 10TAB, it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
RanolazinePhenylbutazone
Critical
How does the drug interact with RENULAZ 500SR 10TAB:
Co-administration of Phenylbutazone and RENULAZ 500SR 10TAB may significantly reduce the blood levels of RENULAZ 500SR 10TAB, which may make the medication ineffective or less effective.

How to manage the interaction:
Taking Phenylbutazone with RENULAZ 500SR 10TAB can lead to an interaction, please consult a doctor before taking it. They can be taken together if advised by a doctor. However, contact a doctor if you experience any symptoms. Do not stop taking any medications without consulting a doctor.
RanolazineCeritinib
Critical
How does the drug interact with RENULAZ 500SR 10TAB:
When Ceritinib is taken with RENULAZ 500SR 10TAB, may significantly increase the blood levels and effects of RENULAZ 500SR 10TAB.

How to manage the interaction:
Taking RENULAZ 500SR 10TAB with Ceritinib together can possibly result in an interaction, but it can be taken if a doctor has advised it. In case you experience any side effects like lightheadedness, fainting, dizziness, or fast or pounding heartbeats, consult a doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
NOT AVAILABLE IN WHOCC-ATC-0NAGrapefruit and Grapefruit Juice
Severe

Drug-Food Interactions

Login/Sign Up

NOT AVAILABLE IN WHOCC-ATC-0NAGrapefruit and Grapefruit Juice
Severe
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Grapefruit juice can increase the levels of RENULAZ 500SR 10TAB, and high blood levels of food can occasionally cause an irregular heart rhythm that may be serious. Grapefruit and grapefruit juice should be avoided while taking RENULAZ 500SR 10TAB if possible.

Diet & Lifestyle Advise

  • Maintain a healthy lifestyle by exercising regularly, maintaining weight, and eating a healthy diet.

  • If you suffer from kidney or liver disease, please inform your doctor before taking the Renulaz 500SR Tablet 10's.
  • Alcohol consumption along with Renulaz 500SR Tablet 10's should be avoided as it may cause excessive drowsiness and increase muscle pain.
  • As a precautionary measure, junk food items from outside and stick to freshly prepared home-cooked meals for a speedy recovery.

Habit Forming

No

Therapeutic Class

ANTIANGINALS

Renulaz 500SR Tablet 10's Substitute

Substitutes safety advice
  • Ranozex Tablet 10's

    17.91per tablet
  • Ranolaz 500 mg Tablet 15's

    18.96per tablet
  • Ranx 500 Tablet 15's

    20.61per tablet
  • Rancad Tablet 15's

    by AYUR

    20.73per tablet
  • Ranogard 500 Tablet 10's

    by AYUR

    9.54per tablet
bannner image

Alcohol

Safe if prescribed

Renulaz 500SR Tablet 10's does not have any reported interaction; hence, if you experience any difficulty, discuss with your doctor.

bannner image

Pregnancy

Unsafe

Renulaz 500SR Tablet 10's should not be used when pregnancy unless necessary. So, inform your doctor if you are pregnant or suspect pregnancy. Your doctor will weigh the benefits and potential risks before prescribing Renulaz 500SR Tablet 10's.

bannner image

Breast Feeding

Unsafe

Renulaz 500SR Tablet 10's should not be used in nursing mothers. Please consult the doctor if you have any concerns regarding this.

bannner image

Driving

Safe if prescribed

Renulaz 500SR Tablet 10's does not have any reported interaction; hence, in case you experience any difficulty, discuss with your doctor.

bannner image

Liver

Caution

Renulaz 500SR Tablet 10's to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.

bannner image

Kidney

Caution

Renulaz 500SR Tablet 10's to be taken with caution, especially if you have a history of kidney diseases/conditions. The dose may have to be adjusted by your doctor.

bannner image

Children

Caution

Renulaz 500SR Tablet 10's is not recommended for children below the age of 18. The safety and effectiveness of Renulaz 500SR Tablet 10's have not been established in children due to limited testing of this drug on children by competent authorities worldwide.

FAQs

Renulaz 500SR Tablet 10's is used alone or with other medicines to treat angina pectoris.
The active substance in Renulaz 500SR Tablet 10's is Ranolazine, which reduces sodium ions flow into the heart muscle cells. This interferes with the activity of special channels on the cell surface called 'sodium-dependent calcium channels through which calcium ions normally enter the cells. This reduces the number of calcium ions that enter the cells. Calcium ions normally cause the heart muscle to contract. By reducing the flow of calcium into the cells, Renulaz 500SR Tablet 10's is thought to help the heart to relax, improving blood flow to the heart muscle and relieving the symptoms of angina pectoris.
No, Renulaz 500SR Tablet 10's does not stop acute attacks (sudden attacks) of angina, but Renulaz 500SR Tablet 10's helps prevent a new attack.
No, alcohol should not be taken with Renulaz 500SR Tablet 10's as it may lead to unwanted side effects and increase angina attacks.
Yes, smoking (tobacco) decreases the efficacy of Renulaz 500SR Tablet 10's, especially when taken for angina (chest pain), so it should be avoided while taking Renulaz 500SR Tablet 10's.
Yes, Renulaz 500SR Tablet 10's can cause an upset stomach when taken empty stomach. So, to avoid it, Renulaz 500SR Tablet 10's should be taken with a meal for best results.
Yes, Renulaz 500SR Tablet 10's can cause drowsiness. If you feel excessively sleepy, please consult your doctor for better advice.
Some major side effects include a rapid, pounding, or irregular heartbeat, difficulty breathing, and fainting. If you encounter any of these symptoms, contact your doctor immediately.
Do not take more than the prescribed dose of Renulaz 500SR Tablet 10's as it may cause overdose. The symptoms of overdose include nausea, vomiting, confusion, dizziness, double vision, fainting, difficulty speaking, uncontrollable shaking of a part of the body, hallucinations and burning, pain, numbness, or tingling in any part of the body. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.
Renulaz 500SR Tablet 10's may increase the blood levels and effects of metoprolol. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your doctor if your condition changes or you experience increased side effects.
Renulaz 500SR Tablet 10's might raise metformin levels, increasing the risk of lactic acidosis. If you are prescribed ranolazine while taking metformin, discuss it with a healthcare physician. They may offer a lesser dose of metformin as a safer alternative.
You can take it if prescribed by the doctor. However, limit simvastatin to 20 mg once daily in individuals taking any dose of Renulaz 500SR Tablet 10's.

Country of origin

India

Manufacturer/Marketer address

405/406, Zee Nayak Building, Mahatma Gandhi Rd, Vile Parle, E, Maharashtra 400057
Other Info - REN0528

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
whatsapp Floating Button