ROLAZIN TABLET is used alone or with other medicines to treat angina pectoris. Angina pectoris is discomfort in the chest or chest pain, which generally occurs due to coronary artery disease (CAD) when an adequate amount of oxygen and blood is not reaching the heart and its muscles. It can also be due to the blockage of the heart's arteries. It helps prevent any further attack of angina by making the heart work more efficiently, and it is used as an add-on to existing treatment in patients whose disease is not adequately controlled by other medicines for angina pectoris, such as beta-blockers or calcium antagonists, or in patients who cannot take these medicines.

The active substance in ROLAZIN TABLET is Ranolazine, which reduces sodium ions flow into the heart muscle cells. This interferes with the activity of special channels on the cell surface called 'sodium-dependent calcium channels, through which calcium ions normally enter the cells. This reduces the number of calcium ions that enter the cells. Calcium ions normally cause the heart muscle to contract. By reducing the flow of calcium into the cells, ROLAZIN TABLET is thought to help the heart relax, improving blood flow to the heart muscle and relieving the symptoms of angina pectoris.

Your doctor will tell you how to take the ROLAZIN TABLET based on your medical condition. You may sometimes experience constipation, dizziness, headache, or feeling sick. Most of these side effects of ROLAZIN TABLET do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Do not consume ROLAZIN TABLET if you are allergic to any component in this medicine. ROLAZIN TABLET should not be stopped even if you feel better for the best results, as it prevents any future harm. If you stop taking the ROLAZIN TABLET on your own, your chest pain can come back in more severe form. If you plan to get pregnant or are pregnant or breastfeeding, please consult your doctor to avoid any unwanted harm to the baby. Some lifestyle modifications are important for best results when taking ROLAZIN TABLET, like smoking cessation, decreasing alcohol intake, eating well, regular exercise, and managing stress. ROLAZIN TABLET should be taken with caution if you have any liver or kidney problems. Also, inform your doctor if you are taking other medications to avoid unwanted side effects or contraindications.

ROLAZIN TABLET is prescribed for treating angina. ROLAZIN TABLET is an anti-anginal medication used to treat angina pectoris. It reduces sodium ions' flow into the heart muscle cells. This interferes with the activity of special channels on the cell surface called ‘sodium-dependent calcium channels’ through which calcium ions normally enter the cells. This reduces the number of calcium ions that enter the cells. Calcium ions normally cause the heart muscle to contract. By reducing the flow of calcium into the cells, ROLAZIN TABLET is thought to help the heart relax, improving blood flow to the heart muscle and relieving the symptoms of angina pectoris.

• Constipation
• Dizziness
• Headache
• Feeling sick

ROLAZIN TABLET should be taken with caution in liver/kidney disease, are pregnant, plan to become pregnant, or are breastfeeding, history of heart disease. Also, grapefruit juice should be avoided while taking ROLAZIN TABLET. As a precautionary measure, junk food items from outside and stick to freshly prepared home-cooked meals for a speedy recovery. Do regular exercise to avoid the feeling of heaviness in the abdomen.

 Drug-Drug Interactions: ROLAZIN TABLET is known to contra-indicate in certain medicines to treat bacterial infections (clarithromycin, telithromycin), lipid-lowering drugs (simvastatin, atorvastatin), fungal infections (itraconazole, ketoconazole, voriconazole, posaconazole), HIV infection (protease inhibitors), depression (nefazodone), antipsychotic medications (haloperidol), or heart rhythm disorders (quinidine, dofetilide, or sotalol).

Drug-Food Interactions: ROLAZIN TABLET may interact with other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Also, grapefruit juice should be avoided while taking ROLAZIN TABLET.

Drug-Disease Interactions: Caution should be exercised if used in patients with severe hepatic impairment, renal disease, long QT interval, or using other QT- prolonging drugs.

• CLARITHROMYCIN
• QUINIDINE
• DOFETILIDE
• SOTALOL
• KETOCONAZOLE
• ITRACONAZOLE

• Maintain a healthy lifestyle by exercising regularly, maintaining weight, and eating a healthy diet.

• If you suffer from kidney or liver disease, please inform your doctor before taking the ROLAZIN TABLET.
• Alcohol consumption along with ROLAZIN TABLET should be avoided as it may cause excessive drowsiness and increase muscle pain.
• As a precautionary measure, junk food items from outside and stick to freshly prepared home-cooked meals for a speedy recovery.

Angina pectoris: Angina pectoris is discomfort in the chest or chest pain that generally occurs due to coronary artery disease (CAD) when an adequate amount of oxygen and blood is not reaching the heart and its muscles. It can also be due to the blockage of the heart's arteries. It helps prevent any further attack of angina by making the heart work more efficiently, but it does not stop an acute attack of angina pectoris.