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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Prutis 100 Softgel Capsule is used to treat idiopathic pulmonary fibrosis (a disease that causes scarring of the lungs). It contains Nintedanib, which helps reduce the scarring and swelling in the lungs by decreasing the release/activity of naturally occurring growth factors in the body, allowing you to breathe better. In some cases, this medicine may cause side effects such as nausea, tiredness, diarrhoea, indigestion, loss of appetite, headache, and photosensitivity. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Composition :

NINTEDANIB-100MG

Manufacturer/Marketer :

Hetero Drugs Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Prutis 100 Softgel Capsule

Prutis 100 Softgel Capsule belongs to the category of 'anti-fibrotic medicine', and it is primarily used to treat idiopathic pulmonary fibrosis (IPF) in adults. IPF is an irreversible disease marked by a progressive decline in lung function. The tissues in the lungs become swollen and scarred over time, which makes it difficult to breathe deeply. The scarring makes it hard for the lungs to work properly.

Prutis 100 Softgel Capsule contains 'Nintedanib', which helps reduce the scarring and swelling in the lungs by decreasing the release/activity of naturally occurring growth factors in the body, allowing you to breathe better. Prutis 100 Softgel Capsule helps in slowing down the progress of idiopathic pulmonary fibrosis.

Always use this medicine as your doctor has told you or per the package leaflet. You must keep to your doctor's instructions to get the maximum benefit. In some cases, you may experience common side effects such as nausea, tiredness, diarrhoea, indigestion, loss of appetite, headache, and photosensitivity. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Consult your doctor before taking Prutis 100 Softgel Capsule if you are pregnant or breastfeeding. Prutis 100 Softgel Capsule may cause tiredness and dizziness, so drive with caution. Avoid consuming alcohol with Prutis 100 Softgel Capsule as it could lead to increased dizziness. Prutis 100 Softgel Capsule is not recommended for children below 18 years as safety and effectiveness have not been established. Prutis 100 Softgel Capsule is listed as pregnancy category D. Because Prutis 100 Softgel Capsule can cause harm to the fetus, women of childbearing potential should be advised to avoid becoming pregnant while receiving treatment with Prutis 100 Softgel Capsule . Consult your doctor if you are breastfeeding; your doctor will decide whether the Prutis 100 Softgel Capsule can be taken by breastfeeding mothers or not. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Uses of Prutis 100 Softgel Capsule

Treatment of Idiopathic pulmonary fibrosis

Directions for Use

Swallow Prutis 100 Softgel Capsule as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Prutis 100 Softgel Capsule is an anti-fibrotic medicine used to treat idiopathic pulmonary fibrosis (IPF) in adults. Prutis 100 Softgel Capsule can help effectively slow the rate of lung function decline by 50%. Prutis 100 Softgel Capsule helps reduce the scarring and swelling in the lungs by decreasing the release/activity of naturally occurring growth factors in the body, allowing you to breathe better. Prutis 100 Softgel Capsule helps in slowing down the progress of idiopathic pulmonary fibrosis.

How Prutis 100 Softgel Capsule Works

Prutis 100 Softgel Capsule contains 'Nintedanib', which helps reduce the scarring and swelling in the lungs by decreasing the release/activity of naturally occurring growth factors in the body, allowing you to breathe better. Prutis 100 Softgel Capsule helps in slowing down the progress of idiopathic pulmonary fibrosis.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Prutis 100 Softgel Capsule

  • Diarrhoea
  • Feeling and being sick
  • Tummy (Abdominal) Pain
  • Loss of appetite and weight loss

What if I have taken an overdose of Prutis 100 Softgel Capsule

Take Prutis 100 Softgel Capsule only as prescribed by the physician. Do not exceed the recommended dose, as it might cause an overdose. If you suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Do not use Prutis 100 Softgel Capsule if you are allergic to any components present in Prutis 100 Softgel Capsule . Prutis 100 Softgel Capsule is listed as pregnancy category D; because Prutis 100 Softgel Capsule can cause harm to the fetus, women of childbearing potential should be advised to avoid becoming pregnant while receiving treatment with Prutis 100 Softgel Capsule . Consult your doctor if you are breastfeeding; your doctor will decide whether the Prutis 100 Softgel Capsule can be taken by breastfeeding mothers or not. Keep your doctor informed about your health condition and medicines to rule out any side effects. Prutis 100 Softgel Capsule may cause tiredness and dizziness, so drive with caution. Avoid consuming alcohol with Prutis 100 Softgel Capsule as it could lead to increased dizziness. Prutis 100 Softgel Capsule is not recommended for children below 18 years as safety and effectiveness have not been established.

Drug-Drug Interactions

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NintedanibPrimidone
Severe
NintedanibLeflunomide
Severe

Drug-Drug Interactions

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NintedanibPrimidone
Severe
How does the drug interact with Prutis 100 Softgel Capsule 10's:
Coadministration of Prutis 100 Softgel Capsule 10's and primidone can reduce the blood levels of Prutis 100 Softgel Capsule 10's.

How to manage the interaction:
Although there is an interaction between Prutis 100 Softgel Capsule 10's and primidone, it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
NintedanibLeflunomide
Severe
How does the drug interact with Prutis 100 Softgel Capsule 10's:
Co-administration of Leflunomide and Prutis 100 Softgel Capsule 10's can increase the risk of liver problems.

How to manage the interaction:
Co-administration of Leflunomide and Prutis 100 Softgel Capsule 10's can lead to an interaction, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
NintedanibRifapentine
Severe
How does the drug interact with Prutis 100 Softgel Capsule 10's:
Coadministration of Prutis 100 Softgel Capsule 10's and Rifapentine can reduce the blood levels of Prutis 100 Softgel Capsule 10's.

How to manage the interaction:
There may be a possibility of interaction between Prutis 100 Softgel Capsule 10's and Rifapentine, but it can be taken if prescribed by a doctor. Contact your doctor if your symptoms do not improve. Do not discontinue any medications without consulting your doctor.
NintedanibPhenobarbital
Severe
How does the drug interact with Prutis 100 Softgel Capsule 10's:
Taking Phenobarbital and Prutis 100 Softgel Capsule 10's can drastically lower Prutis 100 Softgel Capsule 10's levels in the blood, making the medicine less effective in treating the illness.

How to manage the interaction:
Although taking phenobarbital with Prutis 100 Softgel Capsule 10's can lead to interaction, they can be taken if recommended by a doctor. Contact a doctor if your symptoms do not improve. Do not stop using any medications without talking to a doctor.
NintedanibTipranavir
Severe
How does the drug interact with Prutis 100 Softgel Capsule 10's:
Coadministration of Prutis 100 Softgel Capsule 10's and Tipranavir can reduce the blood levels of Prutis 100 Softgel Capsule 10's.

How to manage the interaction:
There may be a possibility of interaction between Prutis 100 Softgel Capsule 10's and Tipranavir, but it can be taken if prescribed by a doctor. Contact your doctor if your symptoms do not improve. Do not discontinue any medications without first consulting your doctor.
NintedanibLomitapide
Severe
How does the drug interact with Prutis 100 Softgel Capsule 10's:
Co-administration of Lomitapide and Prutis 100 Softgel Capsule 10's can increase the risk of liver problems.

How to manage the interaction:
Co-administration of Lomitapide and Prutis 100 Softgel Capsule 10's can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like fever, chills, joint pain, unusual bleeding, skin rash, vomiting, abdominal pain, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
NintedanibCarbamazepine
Severe
How does the drug interact with Prutis 100 Softgel Capsule 10's:
Coadministration of Prutis 100 Softgel Capsule 10's with Carbamazepine can reduce the levels and effects of Prutis 100 Softgel Capsule 10's.

How to manage the interaction:
Although taking carbamazepine and Prutis 100 Softgel Capsule 10's together can possibly result in an interaction, it can be taken if your doctor has prescribed it. Do not stop using any medications without first talking to your doctor.
NintedanibRifampicin
Severe
How does the drug interact with Prutis 100 Softgel Capsule 10's:
Coadministration of Prutis 100 Softgel Capsule 10's with Rifampicin can decrease the blood levels of Prutis 100 Softgel Capsule 10's, which may make the medication less effective.

How to manage the interaction:
Although there is an interaction between Prutis 100 Softgel Capsule 10's and rifampicin, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
NintedanibPhenytoin
Severe
How does the drug interact with Prutis 100 Softgel Capsule 10's:
Coadministration of Phenytoin and Prutis 100 Softgel Capsule 10's may decrease the blood levels of Prutis 100 Softgel Capsule 10's, which may reduce Prutis 100 Softgel Capsule 10's's effectiveness.

How to manage the interaction:
Although taking Phenytoin and Prutis 100 Softgel Capsule 10's together can result in an interaction, it can be taken when your doctor has prescribed it. Contact a doctor if your symptoms do not improve. Do not stop taking any drugs without consulting a doctor.
NintedanibFosphenytoin
Severe
How does the drug interact with Prutis 100 Softgel Capsule 10's:
Coadministration of Prutis 100 Softgel Capsule 10's with Fosphenytoin can reduce the levels of Prutis 100 Softgel Capsule 10's. This can lead to low treatment outcomes.

How to manage the interaction:
Although there is a possible interaction between Prutis 100 Softgel Capsule 10's and Fosphenytoin, you can take these medicines together if prescribed by your doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Watch out for triggers that worsen the cough, such as smoke, foods, air-conditioning, high altitude, etc.
  • Exercise moderately. Eat healthily.
  • Follow pulmonary rehabilitation program. It includes exercise, disease education, and group therapy.
  • Quit smoking and alcohol.
  • Get ample rest.
  • Include green leafy vegetables, sweet potatoes, broccoli, tomatoes, carrots, mangoes, citrus fruits, berries, and cocoa.
  • Lean proteins such as fish, meat, and poultry are the best.
  • Hydration is important. Drink plenty of water, herbal tea, and vegetable and fruit juices.
  • Avoid processed and refined foods.

Habit Forming

No

Therapeutic Class

MISCELLANEOUS

Prutis 100 Softgel Capsule Substitute

Substitutes safety advice
  • Nintena 100 mg Soft Gelatin Capsule 10's

    by AYUR

    74.16per tablet
  • Nindanib 100 Soft Gelatin Capsule 10's

    by AYUR

    88.70per tablet
  • Nintib 100 Soft Gelatin Capsule 10's

    75.11per tablet
  • Fibnib 100 Softgel Capsule 10's

    81.45per tablet
  • Nindev 100 mg Softgel Capsule 10's

    by AYUR

    95.22per tablet
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Alcohol

Caution

It is not known if alcohol interacts with Prutis 100 Softgel Capsule . However, as a precautionary measure, you are recommended not to consume alcohol with the Prutis 100 Softgel Capsule to avoid unpleasant side effects.

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Pregnancy

Unsafe

Prutis 100 Softgel Capsule is listed as pregnancy category D. Because Prutis 100 Softgel Capsule can cause harm to the fetus, women of childbearing potential should be advised to avoid becoming pregnant while receiving treatment with Prutis 100 Softgel Capsule .

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Breast Feeding

Caution

Consult your doctor if you are breastfeeding; your doctor will decide whether Prutis 100 Softgel Capsule can be taken by breastfeeding mothers or not.

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Driving

Caution

Prutis 100 Softgel Capsule may significantly influence your ability to drive and use machines. You should not drive or operate machinery if you feel sick.

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Liver

Caution

Dose adjustment may be needed. Prutis 100 Softgel Capsule is not recommended for patients with severe hepatic impairment. Please consult your doctor if you have a liver impairment or any concerns.

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Kidney

Caution

Dose adjustment may be needed. Prutis 100 Softgel Capsule is not recommended for patients with an end-stage renal disease requiring dialysis. Please consult your doctor if you have kidney impairment or any concerns.

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Children

Caution

Prutis 100 Softgel Capsule is not recommended for children below 18 years as safety and effectiveness have not been established.

FAQs

Prutis 100 Softgel Capsule is used to treat idiopathic pulmonary fibrosis (IPF), a disease marked by a progressive decline in lung function.
Prutis 100 Softgel Capsule helps reduce the scarring and swelling in the lungs by decreasing the release/activity of naturally occurring growth factors in the body, thereby helps you breathe better.
Avoid smoking before starting the treatment while taking Prutis 100 Softgel Capsule as smoking might alter the effectiveness of Prutis 100 Softgel Capsule .
Prutis 100 Softgel Capsule should be stopped when a person faces a serious side effect that affects life quality. Otherwise, it would be best to keep taking Prutis 100 Softgel Capsule until your doctor asks you to stop it.
If you have any surgery, including dental surgery, please inform your doctor if you are taking Prutis 100 Softgel Capsule as your doctor might stop Prutis 100 Softgel Capsule before undergoing surgery.
In elderly patients, the risk of side effects is more if you are taking Prutis 100 Softgel Capsule . For the patients who are elderly, dose adjustment might be required, or your doctor might prescribe any other medication safe for the elderly.

Country of origin

India

Manufacturer/Marketer address

2Nd Floor, 8-3-166/7/1 Erragadda, Hyderabad-500018
Other Info - PRU0094

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