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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Idofnib 100 Capsule is used to treat idiopathic pulmonary fibrosis (a disease that causes scarring of the lungs). It contains Nintedanib, which helps reduce the scarring and swelling in the lungs by decreasing the release/activity of naturally occurring growth factors in the body, allowing you to breathe better. In some cases, this medicine may cause side effects such as nausea, tiredness, diarrhoea, indigestion, loss of appetite, headache, and photosensitivity. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Composition :

NINTEDANIB-100MG

Manufacturer/Marketer :

Lupin Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Idofnib 100 Capsule

Idofnib 100 Capsule belongs to the category of 'anti-fibrotic medicine', and it is primarily used to treat idiopathic pulmonary fibrosis (IPF) in adults. IPF is an irreversible disease marked by a progressive decline in lung function. The tissues in the lungs become swollen and scarred over time, which makes it difficult to breathe deeply. The scarring makes it hard for the lungs to work properly.

Idofnib 100 Capsule contains 'Nintedanib', which helps reduce the scarring and swelling in the lungs by decreasing the release/activity of naturally occurring growth factors in the body, allowing you to breathe better. Idofnib 100 Capsule helps in slowing down the progress of idiopathic pulmonary fibrosis.

Always use this medicine as your doctor has told you or per the package leaflet. You must keep to your doctor's instructions to get the maximum benefit. In some cases, you may experience common side effects such as nausea, tiredness, diarrhoea, indigestion, loss of appetite, headache, and photosensitivity. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Consult your doctor before taking Idofnib 100 Capsule if you are pregnant or breastfeeding. Idofnib 100 Capsule may cause tiredness and dizziness, so drive with caution. Avoid consuming alcohol with Idofnib 100 Capsule as it could lead to increased dizziness. Idofnib 100 Capsule is not recommended for children below 18 years as safety and effectiveness have not been established. Idofnib 100 Capsule is listed as pregnancy category D. Because Idofnib 100 Capsule can cause harm to the fetus, women of childbearing potential should be advised to avoid becoming pregnant while receiving treatment with Idofnib 100 Capsule . Consult your doctor if you are breastfeeding; your doctor will decide whether the Idofnib 100 Capsule can be taken by breastfeeding mothers or not. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Uses of Idofnib 100 Capsule

Treatment of Idiopathic pulmonary fibrosis

Directions for Use

Swallow Idofnib 100 Capsule as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Idofnib 100 Capsule is an anti-fibrotic medicine used to treat idiopathic pulmonary fibrosis (IPF) in adults. Idofnib 100 Capsule can help effectively slow the rate of lung function decline by 50%. Idofnib 100 Capsule helps reduce the scarring and swelling in the lungs by decreasing the release/activity of naturally occurring growth factors in the body, allowing you to breathe better. Idofnib 100 Capsule helps in slowing down the progress of idiopathic pulmonary fibrosis.

How Idofnib 100 Capsule Works

Idofnib 100 Capsule contains 'Nintedanib', which helps reduce the scarring and swelling in the lungs by decreasing the release/activity of naturally occurring growth factors in the body, allowing you to breathe better. Idofnib 100 Capsule helps in slowing down the progress of idiopathic pulmonary fibrosis.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Idofnib 100 Capsule

  • Diarrhoea
  • Feeling and being sick
  • Tummy (Abdominal) Pain
  • Loss of appetite and weight loss

What if I have taken an overdose of Idofnib 100 Capsule

Take Idofnib 100 Capsule only as prescribed by the physician. Do not exceed the recommended dose, as it might cause an overdose. If you suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Do not use Idofnib 100 Capsule if you are allergic to any components present in Idofnib 100 Capsule . Idofnib 100 Capsule is listed as pregnancy category D; because Idofnib 100 Capsule can cause harm to the fetus, women of childbearing potential should be advised to avoid becoming pregnant while receiving treatment with Idofnib 100 Capsule . Consult your doctor if you are breastfeeding; your doctor will decide whether the Idofnib 100 Capsule can be taken by breastfeeding mothers or not. Keep your doctor informed about your health condition and medicines to rule out any side effects. Idofnib 100 Capsule may cause tiredness and dizziness, so drive with caution. Avoid consuming alcohol with Idofnib 100 Capsule as it could lead to increased dizziness. Idofnib 100 Capsule is not recommended for children below 18 years as safety and effectiveness have not been established.

Drug-Drug Interactions

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NintedanibTipranavir
Severe
NintedanibRifapentine
Severe

Drug-Drug Interactions

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NintedanibTipranavir
Severe
How does the drug interact with Idofnib 100 Capsule 10's:
Coadministration of Idofnib 100 Capsule 10's and Tipranavir can reduce the blood levels of Idofnib 100 Capsule 10's.

How to manage the interaction:
There may be a possibility of interaction between Idofnib 100 Capsule 10's and Tipranavir, but it can be taken if prescribed by a doctor. Contact your doctor if your symptoms do not improve. Do not discontinue any medications without first consulting your doctor.
NintedanibRifapentine
Severe
How does the drug interact with Idofnib 100 Capsule 10's:
Coadministration of Idofnib 100 Capsule 10's and Rifapentine can reduce the blood levels of Idofnib 100 Capsule 10's.

How to manage the interaction:
There may be a possibility of interaction between Idofnib 100 Capsule 10's and Rifapentine, but it can be taken if prescribed by a doctor. Contact your doctor if your symptoms do not improve. Do not discontinue any medications without consulting your doctor.
NintedanibPrimidone
Severe
How does the drug interact with Idofnib 100 Capsule 10's:
Coadministration of Idofnib 100 Capsule 10's and primidone can reduce the blood levels of Idofnib 100 Capsule 10's.

How to manage the interaction:
Although there is an interaction between Idofnib 100 Capsule 10's and primidone, it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
NintedanibRifampicin
Severe
How does the drug interact with Idofnib 100 Capsule 10's:
Coadministration of Idofnib 100 Capsule 10's with Rifampicin can decrease the blood levels of Idofnib 100 Capsule 10's, which may make the medication less effective.

How to manage the interaction:
Although there is an interaction between Idofnib 100 Capsule 10's and rifampicin, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
NintedanibCarbamazepine
Severe
How does the drug interact with Idofnib 100 Capsule 10's:
Coadministration of Idofnib 100 Capsule 10's with Carbamazepine can reduce the levels and effects of Idofnib 100 Capsule 10's.

How to manage the interaction:
Although taking carbamazepine and Idofnib 100 Capsule 10's together can possibly result in an interaction, it can be taken if your doctor has prescribed it. Do not stop using any medications without first talking to your doctor.
NintedanibDexamethasone
Severe
How does the drug interact with Idofnib 100 Capsule 10's:
Coadministration of Dexamethasone may lower the blood levels of Idofnib 100 Capsule 10's, making the medication less effective in treating your condition.

How to manage the interaction:
Although there is a possible interaction, Dexamethasone can be taken with Idofnib 100 Capsule 10's if prescribed by the doctor. Contact a doctor if your symptoms do not improve. Do not discontinue any medications without consulting a doctor.
NintedanibLeflunomide
Severe
How does the drug interact with Idofnib 100 Capsule 10's:
Co-administration of Leflunomide and Idofnib 100 Capsule 10's can increase the risk of liver problems.

How to manage the interaction:
Co-administration of Leflunomide and Idofnib 100 Capsule 10's can lead to an interaction, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
NintedanibFosphenytoin
Severe
How does the drug interact with Idofnib 100 Capsule 10's:
Coadministration of Idofnib 100 Capsule 10's with Fosphenytoin can reduce the levels of Idofnib 100 Capsule 10's. This can lead to low treatment outcomes.

How to manage the interaction:
Although there is a possible interaction between Idofnib 100 Capsule 10's and Fosphenytoin, you can take these medicines together if prescribed by your doctor. Do not stop using any medications without a doctor's advice.
NintedanibTeriflunomide
Severe
How does the drug interact with Idofnib 100 Capsule 10's:
Coadministration of Teriflunomide and Idofnib 100 Capsule 10's can increase the risk of liver problems.

How to manage the interaction:
Coadministration of Teriflunomide and Idofnib 100 Capsule 10's can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like fever, chills, joint pain, unusual bleeding, skin rash, loss of appetite, vomiting, abdominal pain, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, contact your doctor immediately.
NintedanibPhenytoin
Severe
How does the drug interact with Idofnib 100 Capsule 10's:
Coadministration of Phenytoin and Idofnib 100 Capsule 10's may decrease the blood levels of Idofnib 100 Capsule 10's, which may reduce Idofnib 100 Capsule 10's's effectiveness.

How to manage the interaction:
Although taking Phenytoin and Idofnib 100 Capsule 10's together can result in an interaction, it can be taken when your doctor has prescribed it. Contact a doctor if your symptoms do not improve. Do not stop taking any drugs without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Watch out for triggers that worsen the cough, such as smoke, foods, air-conditioning, high altitude, etc.
  • Exercise moderately. Eat healthily.
  • Follow pulmonary rehabilitation program. It includes exercise, disease education, and group therapy.
  • Quit smoking and alcohol.
  • Get ample rest.
  • Include green leafy vegetables, sweet potatoes, broccoli, tomatoes, carrots, mangoes, citrus fruits, berries, and cocoa.
  • Lean proteins such as fish, meat, and poultry are the best.
  • Hydration is important. Drink plenty of water, herbal tea, and vegetable and fruit juices.
  • Avoid processed and refined foods.

Habit Forming

No

Therapeutic Class

MISCELLANEOUS

Idofnib 100 Capsule Substitute

Substitutes safety advice
  • Nintena 100 mg Soft Gelatin Capsule 10's

    by AYUR

    74.16per tablet
  • Nindanib 100 Soft Gelatin Capsule 10's

    by AYUR

    88.70per tablet
  • Nintib 100 Soft Gelatin Capsule 10's

    75.11per tablet
  • Fibnib 100 Softgel Capsule 10's

    81.45per tablet
  • Nindev 100 mg Softgel Capsule 10's

    by AYUR

    95.22per tablet
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Alcohol

Caution

It is not known if alcohol interacts with Idofnib 100 Capsule . However, as a precautionary measure, you are recommended not to consume alcohol with the Idofnib 100 Capsule to avoid unpleasant side effects.

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Pregnancy

Unsafe

Idofnib 100 Capsule is listed as pregnancy category D. Because Idofnib 100 Capsule can cause harm to the fetus, women of childbearing potential should be advised to avoid becoming pregnant while receiving treatment with Idofnib 100 Capsule .

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Breast Feeding

Caution

Consult your doctor if you are breastfeeding; your doctor will decide whether Idofnib 100 Capsule can be taken by breastfeeding mothers or not.

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Driving

Caution

Idofnib 100 Capsule may significantly influence your ability to drive and use machines. You should not drive or operate machinery if you feel sick.

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Liver

Caution

Dose adjustment may be needed. Idofnib 100 Capsule is not recommended for patients with severe hepatic impairment. Please consult your doctor if you have a liver impairment or any concerns.

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Kidney

Caution

Dose adjustment may be needed. Idofnib 100 Capsule is not recommended for patients with an end-stage renal disease requiring dialysis. Please consult your doctor if you have kidney impairment or any concerns.

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Children

Caution

Idofnib 100 Capsule is not recommended for children below 18 years as safety and effectiveness have not been established.

FAQs

Idofnib 100 Capsule is used to treat idiopathic pulmonary fibrosis (IPF), a disease marked by a progressive decline in lung function.
Idofnib 100 Capsule helps reduce the scarring and swelling in the lungs by decreasing the release/activity of naturally occurring growth factors in the body, thereby helps you breathe better.
Avoid smoking before starting the treatment while taking Idofnib 100 Capsule as smoking might alter the effectiveness of Idofnib 100 Capsule .
Idofnib 100 Capsule should be stopped when a person faces a serious side effect that affects life quality. Otherwise, it would be best to keep taking Idofnib 100 Capsule until your doctor asks you to stop it.
If you have any surgery, including dental surgery, please inform your doctor if you are taking Idofnib 100 Capsule as your doctor might stop Idofnib 100 Capsule before undergoing surgery.
In elderly patients, the risk of side effects is more if you are taking Idofnib 100 Capsule . For the patients who are elderly, dose adjustment might be required, or your doctor might prescribe any other medication safe for the elderly.

Country of origin

India

Manufacturer/Marketer address

Lupin Ltd, 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India Country of Origin: India
Other Info - IDO0016

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