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Macdanib 100 Softgel Capsule 10'S

Macdanib 100 Softgel Capsule 10'S

Prescription drug
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Composition

NINTEDANIB-100MG

Manufacturer/Marketer

Macleods Pharmaceuticals Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-25

for this medicine

About Macdanib 100 Softgel Capsule

Macdanib 100 Softgel Capsule belongs to the category of 'anti-fibrotic medicine', and it is primarily used to treat idiopathic pulmonary fibrosis (IPF) in adults. IPF is an irreversible disease marked by a progressive decline in lung function. The tissues in the lungs become swollen and scarred over time, which makes it difficult to breathe deeply. The scarring makes it hard for the lungs to work properly.

Macdanib 100 Softgel Capsule contains 'Nintedanib', which helps reduce the scarring and swelling in the lungs by decreasing the release/activity of naturally occurring growth factors in the body, allowing you to breathe better. Macdanib 100 Softgel Capsule helps in slowing down the progress of idiopathic pulmonary fibrosis.

Always use this medicine as your doctor has told you or per the package leaflet. You must keep to your doctor's instructions to get the maximum benefit. In some cases, you may experience common side effects such as nausea, tiredness, diarrhoea, indigestion, loss of appetite, headache, and photosensitivity. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Consult your doctor before taking Macdanib 100 Softgel Capsule if you are pregnant or breastfeeding. Macdanib 100 Softgel Capsule may cause tiredness and dizziness, so drive with caution. Avoid consuming alcohol with Macdanib 100 Softgel Capsule as it could lead to increased dizziness. Macdanib 100 Softgel Capsule is not recommended for children below 18 years as safety and effectiveness have not been established. Macdanib 100 Softgel Capsule is listed as pregnancy category D. Because Macdanib 100 Softgel Capsule can cause harm to the fetus, women of childbearing potential should be advised to avoid becoming pregnant while receiving treatment with Macdanib 100 Softgel Capsule . Consult your doctor if you are breastfeeding; your doctor will decide whether the Macdanib 100 Softgel Capsule can be taken by breastfeeding mothers or not. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Uses of Macdanib 100 Softgel Capsule

Treatment of Idiopathic pulmonary fibrosis

Medicinal Benefits

Macdanib 100 Softgel Capsule is an anti-fibrotic medicine used to treat idiopathic pulmonary fibrosis (IPF) in adults. Macdanib 100 Softgel Capsule can help effectively slow the rate of lung function decline by 50%. Macdanib 100 Softgel Capsule helps reduce the scarring and swelling in the lungs by decreasing the release/activity of naturally occurring growth factors in the body, allowing you to breathe better. Macdanib 100 Softgel Capsule helps in slowing down the progress of idiopathic pulmonary fibrosis.

Directions for Use

Swallow Macdanib 100 Softgel Capsule as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Macdanib 100 Softgel Capsule

  • Diarrhoea
  • Feeling and being sick
  • Tummy (Abdominal) Pain
  • Loss of appetite and weight loss

Drug Warnings

Do not use Macdanib 100 Softgel Capsule if you are allergic to any components present in Macdanib 100 Softgel Capsule . Macdanib 100 Softgel Capsule is listed as pregnancy category D; because Macdanib 100 Softgel Capsule can cause harm to the fetus, women of childbearing potential should be advised to avoid becoming pregnant while receiving treatment with Macdanib 100 Softgel Capsule . Consult your doctor if you are breastfeeding; your doctor will decide whether the Macdanib 100 Softgel Capsule can be taken by breastfeeding mothers or not. Keep your doctor informed about your health condition and medicines to rule out any side effects. Macdanib 100 Softgel Capsule may cause tiredness and dizziness, so drive with caution. Avoid consuming alcohol with Macdanib 100 Softgel Capsule as it could lead to increased dizziness. Macdanib 100 Softgel Capsule is not recommended for children below 18 years as safety and effectiveness have not been established.

Drug Interactions

Drug-Drug Interactions: Macdanib 100 Softgel Capsule may have interaction with medicines used to treat fungal infections (e.g. ketoconazole), medications used to treat bacterial infections/CYP3A4 inhibitors (e.g. erythromycin), drugs that affect your immune system (e.g. cyclosporine), antibiotic medicines used to treat tuberculosis (e.g. rifampicin), medicines to treat seizures (e.g. carbamazepine, phenytoin), and herbal medicines to treat depression (e.g. St. John’s Wort).

Drug-Food Interactions: Avoid grapefruit juice and chargrilled meats.

Drug-Disease Interactions: Macdanib 100 Softgel Capsule may interact with smoking and severe hepatic and end-stage renal impairment requiring dialysis.

Drug-Drug Interactions Checker List

  • KETOCONAZOLE
  • ERYTHROMYCIN
  • CYCLOSPORINE
  • RIFAMPICIN
  • CARBAMAZEPINE
  • PHENYTOIN

Habit Forming

No

Diet & Lifestyle Advise

  • Watch out for triggers that worsen the cough, such as smoke, foods, air-conditioning, high altitude, etc.
  • Exercise moderately. Eat healthily.
  • Follow pulmonary rehabilitation program. It includes exercise, disease education, and group therapy.
  • Quit smoking and alcohol.
  • Get ample rest.
  • Include green leafy vegetables, sweet potatoes, broccoli, tomatoes, carrots, mangoes, citrus fruits, berries, and cocoa.
  • Lean proteins such as fish, meat, and poultry are the best.
  • Hydration is important. Drink plenty of water, herbal tea, and vegetable and fruit juices.
  • Avoid processed and refined foods.

Special Advise

  • Regular blood tests and occasional tests of your bone marrow will be carried out to check whether the treatment is working. If it does work, it will usually be taken for life.

Disease/Condition Glossary

Idiopathic pulmonary fibrosis (IPF): Idiopathic pulmonary fibrosis belongs to a group of interstitial lung diseases. It is an irreversible chronic disease marked by a progressive decline in lung function. The tissues in the lungs become inflamed and scarred over time, due to which it gets difficult to breathe properly. The scar tissue, known as fibrosis, becomes thick /stiff over time, making it hard for the lungs to work efficiently. This causes decreased lung function, which leads to increased breathlessness and coughing. Breathing difficulties can lead to other medical problems. Symptoms of IPF are shortness of breath, persistent dry cough, loss of appetite, weight loss, and rounded and widened tips of the fingers and toes.

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Alcohol

Caution

It is not known if alcohol interacts with Macdanib 100 Softgel Capsule . However, as a precautionary measure, you are recommended not to consume alcohol with the Macdanib 100 Softgel Capsule to avoid unpleasant side effects.

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Pregnancy

Unsafe

Macdanib 100 Softgel Capsule is listed as pregnancy category D. Because Macdanib 100 Softgel Capsule can cause harm to the fetus, women of childbearing potential should be advised to avoid becoming pregnant while receiving treatment with Macdanib 100 Softgel Capsule .

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Breast Feeding

Caution

Consult your doctor if you are breastfeeding; your doctor will decide whether Macdanib 100 Softgel Capsule can be taken by breastfeeding mothers or not.

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Driving

Caution

Macdanib 100 Softgel Capsule may significantly influence your ability to drive and use machines. You should not drive or operate machinery if you feel sick.

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Liver

Caution

Dose adjustment may be needed. Macdanib 100 Softgel Capsule is not recommended for patients with severe hepatic impairment. Please consult your doctor if you have a liver impairment or any concerns.

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Kidney

Caution

Dose adjustment may be needed. Macdanib 100 Softgel Capsule is not recommended for patients with an end-stage renal disease requiring dialysis. Please consult your doctor if you have kidney impairment or any concerns.

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Children

Caution

Macdanib 100 Softgel Capsule is not recommended for children below 18 years as safety and effectiveness have not been established.

Country of origin

INDIA

Manufacturer/Marketer address

Atlanta Arcade, Marol Church Road, Andheri (East), Mumbai - 400059, India.
Other Info - MAC0414

Author Details

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FAQs

Macdanib 100 Softgel Capsule is used to treat idiopathic pulmonary fibrosis (IPF), a disease marked by a progressive decline in lung function.
Macdanib 100 Softgel Capsule helps reduce the scarring and swelling in the lungs by decreasing the release/activity of naturally occurring growth factors in the body, thereby helps you breathe better.
Avoid smoking before starting the treatment while taking Macdanib 100 Softgel Capsule as smoking might alter the effectiveness of Macdanib 100 Softgel Capsule .
Macdanib 100 Softgel Capsule should be stopped when a person faces a serious side effect that affects life quality. Otherwise, it would be best to keep taking Macdanib 100 Softgel Capsule until your doctor asks you to stop it.
If you have any surgery, including dental surgery, please inform your doctor if you are taking Macdanib 100 Softgel Capsule as your doctor might stop Macdanib 100 Softgel Capsule before undergoing surgery.
In elderly patients, the risk of side effects is more if you are taking Macdanib 100 Softgel Capsule . For the patients who are elderly, dose adjustment might be required, or your doctor might prescribe any other medication safe for the elderly.

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