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Written By ,
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Last Updated Oct 9, 2024 | 12:40 PM IST
Pandex Tablet is used to treat migraine headaches. Besides this, it can also be used to reduce pain in rheumatoid arthritis, gout and dysmenorrhea (menstrual pain). It contains Naproxen and Domperidone, which works by reducing certain chemical substances (prostaglandins) that cause pain and swelling. Also, it prevents nausea and vomiting symptoms by blocking certain receptors (like dopamine and serotonin) that stimulate the vomiting centre in the brain. It may cause common side effects such as dryness of the mouth, abdominal pain, constipation, drowsiness, dizziness, visual disturbances, hearing problems and headache. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Apr-26

About Pandex Tablet

Pandex Tablet belongs to the group of medications called analgesics. It treats migraine headaches. Besides this, it can also be used to reduce pain in rheumatoid arthritis, gout and dysmenorrhea (menstrual pain). Migraine is a condition characterized by intense headaches. Pain is a symptom that occurs due to various underlying conditions.

Pandex Tablet is a combination of two drugs: Naproxen and Domperidone. Naproxen works by blocking the action of the cyclo-oxygenase (COX) enzyme in the body that produces certain chemical substances such as prostaglandins that cause pain and swelling. Domperidone is an antiemetic agent which prevents nausea and vomiting symptoms by blocking certain receptors (like dopamine and serotonin) that stimulate the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain.

Take Pandex Tablet as prescribed by your doctor. You are advised to take Pandex Tablet for as long as your doctor has prescribed it for you based on your medical condition. Common side-effects of Pandex Tablet are dryness of the mouth, abdominal pain, constipation, drowsiness, dizziness, visual disturbances, hearing problems and headache. Consult your doctor if you feel any discomfort.

Before taking the Pandex Tablet , let your doctor know about all your allergic or hypersensitivity reactions to medicines or food. If you are pregnant or breastfeeding, please tell your doctor so that your doctor will weigh the benefits and any potential risks before prescribing it to you. Also, inform the doctor if you have a history of heart rhythm problems or ulcers due to pain killers. Patients with age above 65 years, pre-existing cardiac diseases such as heart failure, hypertension or stroke, gastrointestinal bleeding (due to pain killers), gastric ulcers, respiratory diseases such as asthma, liver diseases, kidney diseases or bleeding disorders should use Pandex Tablet only when prescribed by a doctor.

Uses of Pandex Tablet

Treatment of Migraine headache, Pain associated with conditions like rheumatoid arthritis, gout and dysmenorrhea (menstrual pain).

Medicinal Benefits

Pandex Tablet is a combination of naproxen and domperidone. Naproxen is an anti-inflammatory (reduce inflammation) and analgesic (reduce pain) agent. It inhibits the synthesis of prostaglandins, which are inflammatory mediators, thereby reducing pain and inflammation. Domperidone acts by enhancing gastric peristalsis (movements) to empty stomach. Easy movement of food through the stomach helps in relieving nausea and vomiting. It blocks the dopamine receptors present at the chemoreceptor trigger zone (responsible for regulating nausea and vomiting).

Side Effects of Pandex Tablet

  • Abdominal pain

  • Constipation

  • Indigestion

  • Flatulence

  • Dry mouth

  • Glossitis (inflammation of the tongue)

  • Diarrhoea

  • Drowsiness

  • Dizziness

  • Headache

  • Vision problems

  • Hearing problems

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Inform your doctor if you are taking any of the anticoagulants (warfarin), other NSAIDs (ibuprofen, ketorolac), corticosteroids (prednisolone), antidepressants (citalopram, fluoxetine, paroxetine, duloxetine, venlafaxine), or any other dietary or herbal supplements. Long-term use of nonsteroidal anti-inflammatory drugs (NSAIDs) (other than aspirin) such as naproxen may increase the risk of heart attack or stroke and stomach ulcers. The risk of developing ulcers is higher if you have a history of ulcers, have bleeding disorders, older in age, alcoholic or have multiple diseases. The risk of having a heart attack increases if you smoke, or you or your family has a history of heart failure, stroke, or hypertension. Call for medical help immediately, if you experience chest pain, shortness of breath, blood in the stool or dark stools, heartburn, or any other abnormal signs.

Therapeutic Class

ANALGESICS

Diet & Lifestyle Advise

  • Drink plenty of fluids to avoid gastrointestinal problems.

  • Avoid triggers that can increase your migraine headache.

  • Take enough rest.

  • Acupuncture, massage and physical therapy may also be helpful.

  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listen to soothing music.

  • Avoid smoking and alcohol consumption.

  • Performing yoga may also help in improving joint flexibility and pain management.

  • Get adequate sleep as resting the muscles can help in reducing inflammation and swelling.

Habit Forming

No

What if I have taken an overdose of Pandex Tablet

Do not take more than the prescribed dose of Pandex Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.
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Alcohol

Caution

It is advised not to take alcohol as Pandex Tablet can cause dizziness or drowsiness.

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Pregnancy

Caution

Pandex Tablet should be used in pregnant women only if clinically needed, and the benefits outweigh the risks.

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Breast Feeding

Caution

Pandex Tablet should be used in breastfeeding mothers only if the benefits outweigh the risks.

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Driving

Unsafe

It is unsafe to drive after taking Pandex Tablet as it impacts your ability to drive or operate machinery.

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Liver

Caution

Limited information was available for the use of Pandex Tablet in patients suffering from liver impairment. Please consult your doctor if you have any concerns regarding using Pandex Tablet in patients with liver impairment. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Caution

Limited information was available for the use of Pandex Tablet in patients suffering from kidney impairment. Please consult your doctor if you have any concerns regarding using Pandex Tablet in patients with kidney impairment. Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Caution

Pandex Tablet should be used in children below 12 years of age only when prescribed by a child specialist.

Country of origin

India

Manufacturer/Marketer address

16Th Floor, Godrej Bkc, Plot C, G Block, Bandra-Kurla Complex, Bandra (East), Mumbai 400 051, India.
Other Info - PAN0774

FAQs

Pandex Tablet is used to treat migraine headaches, pain associated with conditions like rheumatoid arthritis, gout and dysmenorrhea (menstrual pain).
Naproxen works by inhibiting the cyclo-oxygenase (COX) enzyme in the body, which creates chemical compounds such as prostaglandins, which induce pain and swelling. Domperidone is an antiemetic that blocks certain receptors (such as dopamine and serotonin) that stimulate the brain's vomiting centre (chemoreceptor trigger zone - CTZ).
Pandex Tablet cannot permanently cure migraine. It can provide relief from pain and headache.
Pandex Tablet on prolonged or frequent use can cause liver or kidney problems. Therefore, it should be only used for a duration as prescribed by the doctor.
Arthritis is a chronic condition of joints with pain and inflammation. Pandex Tablet does not cure arthritis but relieves symptoms of arthritis-like joint pain, swelling and stiffness.
Yes, Pandex Tablet may increase the risk of heart problems such as heart attack and stroke, especially when used in high doses or for a prolonged duration. It is advised to inform your doctor if you have any of these conditions or have a history of heart problems or stroke before taking the Pandex Tablet .
Dry mouth may be caused by Domperidone in Pandex Tablet . Chew a sugar-free sweet or sugar-free gum.

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