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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Nintib 150 Capsules is used to treat idiopathic pulmonary fibrosis (a disease that causes scarring of the lungs). It contains Nintedanib, which helps reduce the scarring and swelling in the lungs by decreasing the release/activity of naturally occurring growth factors in the body, allowing you to breathe better. In some cases, this medicine may cause side effects such as nausea, tiredness, diarrhoea, indigestion, loss of appetite, headache, and photosensitivity. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Composition :

NINTEDANIB-150MG

Manufacturer/Marketer :

Cipla Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Nintib 150 Capsules

Nintib 150 Capsules belongs to the category of 'anti-fibrotic medicine', and it is primarily used to treat idiopathic pulmonary fibrosis (IPF) in adults. IPF is an irreversible disease marked by a progressive decline in lung function. The tissues in the lungs become swollen and scarred over time, which makes it difficult to breathe deeply. The scarring makes it hard for the lungs to work properly.

Nintib 150 Capsules contains 'Nintedanib', which helps reduce the scarring and swelling in the lungs by decreasing the release/activity of naturally occurring growth factors in the body, allowing you to breathe better. Nintib 150 Capsules helps in slowing down the progress of idiopathic pulmonary fibrosis.

Always use this medicine as your doctor has told you or per the package leaflet. You must keep to your doctor's instructions to get the maximum benefit. In some cases, you may experience common side effects such as nausea, tiredness, diarrhoea, indigestion, loss of appetite, headache, and photosensitivity. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Consult your doctor before taking Nintib 150 Capsules if you are pregnant or breastfeeding. Nintib 150 Capsules may cause tiredness and dizziness, so drive with caution. Avoid consuming alcohol with Nintib 150 Capsules as it could lead to increased dizziness. Nintib 150 Capsules is not recommended for children below 18 years as safety and effectiveness have not been established. Nintib 150 Capsules is listed as pregnancy category D. Because Nintib 150 Capsules can cause harm to the fetus, women of childbearing potential should be advised to avoid becoming pregnant while receiving treatment with Nintib 150 Capsules . Consult your doctor if you are breastfeeding; your doctor will decide whether the Nintib 150 Capsules can be taken by breastfeeding mothers or not. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Uses of Nintib 150 Capsules

Treatment of Idiopathic pulmonary fibrosis

Directions for Use

Swallow Nintib 150 Capsules as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Nintib 150 Capsules is an anti-fibrotic medicine used to treat idiopathic pulmonary fibrosis (IPF) in adults. Nintib 150 Capsules can help effectively slow the rate of lung function decline by 50%. Nintib 150 Capsules helps reduce the scarring and swelling in the lungs by decreasing the release/activity of naturally occurring growth factors in the body, allowing you to breathe better. Nintib 150 Capsules helps in slowing down the progress of idiopathic pulmonary fibrosis.

How Nintib 150 Capsules Works

Nintib 150 Capsules contains 'Nintedanib', which helps reduce the scarring and swelling in the lungs by decreasing the release/activity of naturally occurring growth factors in the body, allowing you to breathe better. Nintib 150 Capsules helps in slowing down the progress of idiopathic pulmonary fibrosis.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Nintib 150 Capsules

  • Diarrhoea
  • Feeling and being sick
  • Tummy (Abdominal) Pain
  • Loss of appetite and weight loss

What if I have taken an overdose of Nintib 150 Capsules

Take Nintib 150 Capsules only as prescribed by the physician. Do not exceed the recommended dose, as it might cause an overdose. If you suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Do not use Nintib 150 Capsules if you are allergic to any components present in Nintib 150 Capsules . Nintib 150 Capsules is listed as pregnancy category D; because Nintib 150 Capsules can cause harm to the fetus, women of childbearing potential should be advised to avoid becoming pregnant while receiving treatment with Nintib 150 Capsules . Consult your doctor if you are breastfeeding; your doctor will decide whether the Nintib 150 Capsules can be taken by breastfeeding mothers or not. Keep your doctor informed about your health condition and medicines to rule out any side effects. Nintib 150 Capsules may cause tiredness and dizziness, so drive with caution. Avoid consuming alcohol with Nintib 150 Capsules as it could lead to increased dizziness. Nintib 150 Capsules is not recommended for children below 18 years as safety and effectiveness have not been established.

Drug-Drug Interactions

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NintedanibDexamethasone
Severe
NintedanibRifapentine
Severe

Drug-Drug Interactions

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NintedanibDexamethasone
Severe
How does the drug interact with Nintib 150 Capsule 30's:
Coadministration of Dexamethasone may lower the blood levels of Nintib 150 Capsule 30's, making the medication less effective in treating your condition.

How to manage the interaction:
Although there is a possible interaction, Dexamethasone can be taken with Nintib 150 Capsule 30's if prescribed by the doctor. Contact a doctor if your symptoms do not improve. Do not discontinue any medications without consulting a doctor.
NintedanibRifapentine
Severe
How does the drug interact with Nintib 150 Capsule 30's:
Coadministration of Nintib 150 Capsule 30's and Rifapentine can reduce the blood levels of Nintib 150 Capsule 30's.

How to manage the interaction:
There may be a possibility of interaction between Nintib 150 Capsule 30's and Rifapentine, but it can be taken if prescribed by a doctor. Contact your doctor if your symptoms do not improve. Do not discontinue any medications without consulting your doctor.
NintedanibLomitapide
Severe
How does the drug interact with Nintib 150 Capsule 30's:
Co-administration of Lomitapide and Nintib 150 Capsule 30's can increase the risk of liver problems.

How to manage the interaction:
Co-administration of Lomitapide and Nintib 150 Capsule 30's can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like fever, chills, joint pain, unusual bleeding, skin rash, vomiting, abdominal pain, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
NintedanibFosphenytoin
Severe
How does the drug interact with Nintib 150 Capsule 30's:
Coadministration of Nintib 150 Capsule 30's with Fosphenytoin can reduce the levels of Nintib 150 Capsule 30's. This can lead to low treatment outcomes.

How to manage the interaction:
Although there is a possible interaction between Nintib 150 Capsule 30's and Fosphenytoin, you can take these medicines together if prescribed by your doctor. Do not stop using any medications without a doctor's advice.
NintedanibTipranavir
Severe
How does the drug interact with Nintib 150 Capsule 30's:
Coadministration of Nintib 150 Capsule 30's and Tipranavir can reduce the blood levels of Nintib 150 Capsule 30's.

How to manage the interaction:
There may be a possibility of interaction between Nintib 150 Capsule 30's and Tipranavir, but it can be taken if prescribed by a doctor. Contact your doctor if your symptoms do not improve. Do not discontinue any medications without first consulting your doctor.
NintedanibCarbamazepine
Severe
How does the drug interact with Nintib 150 Capsule 30's:
Coadministration of Nintib 150 Capsule 30's with Carbamazepine can reduce the levels and effects of Nintib 150 Capsule 30's.

How to manage the interaction:
Although taking carbamazepine and Nintib 150 Capsule 30's together can possibly result in an interaction, it can be taken if your doctor has prescribed it. Do not stop using any medications without first talking to your doctor.
NintedanibPrimidone
Severe
How does the drug interact with Nintib 150 Capsule 30's:
Coadministration of Nintib 150 Capsule 30's and primidone can reduce the blood levels of Nintib 150 Capsule 30's.

How to manage the interaction:
Although there is an interaction between Nintib 150 Capsule 30's and primidone, it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
NintedanibLeflunomide
Severe
How does the drug interact with Nintib 150 Capsule 30's:
Co-administration of Leflunomide and Nintib 150 Capsule 30's can increase the risk of liver problems.

How to manage the interaction:
Co-administration of Leflunomide and Nintib 150 Capsule 30's can lead to an interaction, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
NintedanibTeriflunomide
Severe
How does the drug interact with Nintib 150 Capsule 30's:
Coadministration of Teriflunomide and Nintib 150 Capsule 30's can increase the risk of liver problems.

How to manage the interaction:
Coadministration of Teriflunomide and Nintib 150 Capsule 30's can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like fever, chills, joint pain, unusual bleeding, skin rash, loss of appetite, vomiting, abdominal pain, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, contact your doctor immediately.
NintedanibPhenobarbital
Severe
How does the drug interact with Nintib 150 Capsule 30's:
Taking Phenobarbital and Nintib 150 Capsule 30's can drastically lower Nintib 150 Capsule 30's levels in the blood, making the medicine less effective in treating the illness.

How to manage the interaction:
Although taking phenobarbital with Nintib 150 Capsule 30's can lead to interaction, they can be taken if recommended by a doctor. Contact a doctor if your symptoms do not improve. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Watch out for triggers that worsen the cough, such as smoke, foods, air-conditioning, high altitude, etc.
  • Exercise moderately. Eat healthily.
  • Follow pulmonary rehabilitation program. It includes exercise, disease education, and group therapy.
  • Quit smoking and alcohol.
  • Get ample rest.
  • Include green leafy vegetables, sweet potatoes, broccoli, tomatoes, carrots, mangoes, citrus fruits, berries, and cocoa.
  • Lean proteins such as fish, meat, and poultry are the best.
  • Hydration is important. Drink plenty of water, herbal tea, and vegetable and fruit juices.
  • Avoid processed and refined foods.

Habit Forming

No

Therapeutic Class

MISCELLANEOUS

Nintib 150 Capsules Substitute

Substitutes safety advice
  • Nintena 150 Soft Gelatin Capsule 10's

    by AYUR

    88.92per tablet
  • Nintib 150 Soft Gelatin Capsule 10's

    92.57per tablet
  • Nindanib 150 Soft Gelatin Capsule 10's

    by AYUR

    106.43per tablet
  • Idofnib-150 Capsule 10's

    by AYUR

    107.64per tablet
  • Nindev 150 mg Softgel Capsule 10's

    by AYUR

    108.27per tablet
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Alcohol

Caution

It is not known if alcohol interacts with Nintib 150 Capsules . However, as a precautionary measure, you are recommended not to consume alcohol with the Nintib 150 Capsules to avoid unpleasant side effects.

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Pregnancy

Unsafe

Nintib 150 Capsules is listed as pregnancy category D. Because Nintib 150 Capsules can cause harm to the fetus, women of childbearing potential should be advised to avoid becoming pregnant while receiving treatment with Nintib 150 Capsules .

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Breast Feeding

Caution

Consult your doctor if you are breastfeeding; your doctor will decide whether Nintib 150 Capsules can be taken by breastfeeding mothers or not.

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Driving

Caution

Nintib 150 Capsules may significantly influence your ability to drive and use machines. You should not drive or operate machinery if you feel sick.

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Liver

Caution

Dose adjustment may be needed. Nintib 150 Capsules is not recommended for patients with severe hepatic impairment. Please consult your doctor if you have a liver impairment or any concerns.

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Kidney

Caution

Dose adjustment may be needed. Nintib 150 Capsules is not recommended for patients with an end-stage renal disease requiring dialysis. Please consult your doctor if you have kidney impairment or any concerns.

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Children

Caution

Nintib 150 Capsules is not recommended for children below 18 years as safety and effectiveness have not been established.

FAQs

Nintib 150 Capsules is used to treat idiopathic pulmonary fibrosis (IPF), a disease marked by a progressive decline in lung function.
Nintib 150 Capsules helps reduce the scarring and swelling in the lungs by decreasing the release/activity of naturally occurring growth factors in the body, thereby helps you breathe better.
Avoid smoking before starting the treatment while taking Nintib 150 Capsules as smoking might alter the effectiveness of Nintib 150 Capsules .
Nintib 150 Capsules should be stopped when a person faces a serious side effect that affects life quality. Otherwise, it would be best to keep taking Nintib 150 Capsules until your doctor asks you to stop it.
If you have any surgery, including dental surgery, please inform your doctor if you are taking Nintib 150 Capsules as your doctor might stop Nintib 150 Capsules before undergoing surgery.
In elderly patients, the risk of side effects is more if you are taking Nintib 150 Capsules . For the patients who are elderly, dose adjustment might be required, or your doctor might prescribe any other medication safe for the elderly.

Country of origin

India

Manufacturer/Marketer address

Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013.
Other Info - NIN0050

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