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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Dec 7, 2024 | 2:20 PM IST
Nimodip 10 mg Infusion is used to prevent brain damage due to subarachnoid haemorrhage. It contains Nimodipine, which relaxes the smooth muscles of the small blood vessels in the brain, thereby allowing narrowed blood vessels to open up. This helps increase blood flow and circulation, reduce blood pressure, and lower the risk of damage caused by insufficient blood flow to the brain after bleeding.
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Composition

NIMODIPINE-10MG

Manufacturer/Marketer

USV Pvt Ltd

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Nimodip 10 mg Infusion

Nimodip 10 mg Infusion belongs to a group of medicines called calcium channel blockers indicated as prophylaxis and treatment of ischaemic neurological deficits caused by narrowing of blood vessels following subarachnoid haemorrhage of aneurysmal origin. Subarachnoid haemorrhage is the bleeding around the brain which is usually the result of bleeding from an aneurysm (a weakened area in a blood vessel).
 
Nimodip 10 mg Infusion contains ‘Nimodipine’ that relaxes the smooth muscles of the small blood vessels in the brain, thereby allowing narrowed blood vessels to open up. This helps in increasing blood flow & circulation, reduces blood pressure, and lowers the risk of damage caused by insufficient blood flow to the brain after bleeding.
 
In some cases, Nimodip 10 mg Infusion may cause side effects such as low blood pressure, vasodilation, nausea, constipation, flatulence, and diarrhoea. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if the side effects persist or worsen.
 
Consult your doctor if you are pregnant. Avoid breastfeeding while on treatment with Nimodip 10 mg Infusion. Drive or operate machinery only if you are alert as Nimodip 10 mg Infusion may cause dizziness. Nimodip 10 mg Infusion is not recommended for children below 18 years as safety and effectiveness have not been established. Inform your doctor about all the medicines you are taking and your health condition to rule out any unpleasant side effects/interactions.

Uses of Nimodip 10 mg Infusion

Prevention of brain damage due to subarachnoid haemorrhage

Medicinal Benefits

Nimodip 10 mg Infusion belongs to the group of medicines called calcium channel blockers indicated as prophylaxis and treatment of ischaemic neurological deficits caused by cerebral vasospasm (narrowing of blood vessels) following aneurysmal subarachnoid haemorrhage. Nimodip 10 mg Infusion contains ‘Nimodipine’ that relaxes the smooth muscles of the small blood vessels in the brain, thereby allowing narrowed blood vessels to open up. This helps in increasing blood flow & circulation, reduces blood pressure, and lowers the risk of damage caused by insufficient blood flow to the brain after bleeding.

Directions for Use

Nimodip 10 mg Infusion will be administered by a healthcare professional; do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Nimodip 10 mg Infusion

  • Low blood pressure
  • Vasodilation
  • Nausea
  • Constipation
  • Flatulence
  • Diarrhoea

Drug Warnings

Do not take Nimodip 10 mg Infusion if you are allergic to any of its components. Inform your doctor if you have low blood pressure, fluid retention in the brain, bowel obstruction, epilepsy, alcoholism, heart kidney, or liver problems. Consult your doctor if you are pregnant. Avoid breastfeeding while on treatment with Nimodip 10 mg Infusion. Drive or operate machinery only if you are alert as Nimodip 10 mg Infusion may cause dizziness. Nimodip 10 mg Infusion is not recommended for children below 18 years as safety and effectiveness have not been established.

Drug Interactions

Drug-Drug Interactions: Nimodip 10 mg Infusion may interact with antacid (cimetidine), anti-convulsant (phenobarbitone, phenytoin, carbamazepine, sodium valproate), anti-depressant (fluoxetine, nefazodone, nortriptyline), diuretic (furosemide), medicines used to treat tuberculosis (rifampicin), anti-HIV (indinavir, ritonavir, zidovudine), antibiotic (erythromycin, quinupristin+dalfopristin, aminoglycosides, cephalosporins).

Drug-Food Interactions: Avoid consuming grapefruit or its juice. Treatment with Nimodip 10 mg Infusion should not be started within 4 days of eating grapefruit or drinking grapefruit juice.

Drug-Disease Interactions: Inform your doctor if you have low blood pressure, fluid retention in the brain, bowel obstruction, epilepsy, alcoholism, or heart problems.

Drug-Drug Interactions Checker List

  • CIMETIDINE
  • PHENOBARBITONE
  • PHENYTOIN
  • CARBAMAZEPINE
  • SODIUM VALPROATE
  • FLUOXETINE
  • NEFAZODONE
  • NORTRIPTYLINE
  • FUROSEMIDE
  • RIFAMPICIN
  • INDINAVIR
  • RITONAVIR
  • ZIDOVUDINE
  • ERYTHROMYCIN
  • QUINUPRISTIN+DALFOPRISTIN

Habit Forming

No

Diet & Lifestyle Advise

  • Avoid smoking and alcohol consumption.
  • Maintain a healthy weight with proper diet and exercise.
  • Include foods such as whole-grain bread, low-fat dairy products, lean meat, beans, and fish.
  • Exercise as directed by the physician. It helps in lowering blood pressure, cholesterol, blood sugar and weight.
  • Manage stress with meditation, music, or deep breathing.

Special Advise

  • Regular monitoring of blood pressure levels and heart rate is advised.
  • Your doctor may advise regular liver function tests, and blood tests to check your progress.

Disease/Condition Glossary

Subarachnoid haemorrhage: Subarachnoid haemorrhage is the bleeding in the subarachnoid space in the brain which is usually a result of bleeding from an aneurysm (a weakened area in the blood vessel). Subarachnoid space is the space where cerebrospinal fluid circulates, which protects the brain from injury. Due to haemorrhage, the blood supply to the brain is reduced, which leads to disruption of brain functions leading to its damage. The main symptom of subarachnoid haemorrhage is a sudden, severe headache. Other symptoms include neck pain, shoulder pain, confusion, seizures, irritability, double vision, and rapid loss of alertness.

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Alcohol

Consult your doctor

It is not known whether alcohol affects Nimodip 10 mg Infusion. Please consult your doctor.

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Pregnancy

Caution

Please inform your doctor if you are pregnant. Your doctor will weigh the benefits and the risks before prescribing Nimodip 10 mg Infusion in pregnancy.

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Breast Feeding

Unsafe

Nimodip 10 mg Infusion is not recommended during breastfeeding. However, if it is prescribed by your doctor, avoid breastfeeding while on treatment with Nimodip 10 mg Infusion.

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Driving

Caution

Nimodip 10 mg Infusion may cause dizziness. Drive and operate machinery only if you are alert.

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Liver

Caution

If you have liver disease, please inform your doctor before receiving Nimodip 10 mg Infusion. Your doctor may adjust the dose or prescribe a suitable alternative based on your condition.

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Kidney

Caution

If you have kidney disease, please inform your doctor before receiving Nimodip 10 mg Infusion. Your doctor may adjust the dose or prescribe a suitable alternative based on your condition.

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Children

Unsafe

Nimodip 10 mg Infusion is not recommended for children below 18 years as safety and effectiveness have not been established.

Country of origin

India

Manufacturer/Marketer address

Arvind Vithal Gandhi Chowk, BSD Marg, Station Road, Govandi East, Mumbai - 400 088. , India.
Other Info - NIM0150

Author Details

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FAQs

Nimodip 10 mg Infusion is used to prevent brain damage due to subarachnoid haemorrhage.
Nimodip 10 mg Infusion relaxes the smooth muscles of the small blood vessels in the brain, thereby allowing narrowed blood vessels to open up. This helps in increasing blood flow & circulation, reduces blood pressure, and lowers the risk of damage caused by insufficient blood flow to the brain after bleeding.
Nimodip 10 mg Infusion might impair sperm function. So, talk to your doctor if you are trying to father a child or if you have any concerns regarding this.
Diarrhoea could be a side effect of Nimodip 10 mg Infusion. Drink plenty of fluids and eat non-spicy food if you experience diarrhoea. Consult your doctor if the condition persists or worsens.
Consult your doctor before taking anti-hypertensive medicines whilst on treatment with Nimodip 10 mg Infusion as it may increase the blood pressure lowering effect of concomitantly used anti-hypertensive medicines. Regular monitoring of blood pressure levels is advised.
Nimodip 10 mg Infusion may cause constipation in some cases. However, it is not necessary for everyone taking Nimodip 10 mg Infusion to experience this side effect. If the condition persists or worsens, consult a doctor.
Nimodip 10 mg Infusion contains Nimodipine which belongs to the group of medicines called calcium channel blockers used to prevent brain damage due to subarachnoid haemorrhage.
Avoid grapefruit and its juice during treatment with Nimodip 10 mg Infusion as it might increase the blood levels of the medicine. Do not drive or operate machinery as it may cause dizziness.
Nimodip 10 mg Infusion is administered as a continuous IV infusion by a healthcare professional; do not self-administer.
Nimodip 10 mg Infusion should not be taken along with the tablet form of nimodipine. However, if needed your doctor may ask you to switch to the tablet form of nimodipine after completion of treatment with Nimodip 10 mg Infusion.
Nimodip 10 mg Infusion may cause side effects such as low blood pressure, vasodilation, nausea, constipation, flatulence, and diarrhoea. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if the side effects persist or worsen.

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