Neutral-DSR Capsule belongs to a group of medicines called gastrointestinal agents used to treat acidity, heartburn, gastro-oesophageal reflux disease (GERD), Zollinger-Ellison syndrome, nausea, vomiting, the fullness of stomach, bloating, gas, helicobacter pylori infection, gastric and duodenal ulcers. Acidity occurs when the gastric glands produce more stomach acid required for digestion. 

Neutral-DSR Capsule is a combination of two drugs: Rabeprazole sodium (proton pump inhibitor) and Domperidone (a dopamine antagonist). Rabeprazole sodium works by blocking the action of an enzyme called gastric proton pump, which is responsible for the production of acid. Domperidone works by increasing the movements and contractions of the stomach muscle. Together, Neutral-DSR Capsule helps in treating acidity-related problems.

Take Neutral-DSR Capsule 30-60minutes prior to food. Depending on your medical condition, you are advised to take Neutral-DSR Capsule for as long as your doctor has prescribed it for you. Sometimes, you may experience common side effects such as dry mouth, stomach pain, diarrhoea, headache, and flatulence. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Inform your doctor before taking Neutral-DSR Capsule if you have a history of gastrointestinal bleeding or intestinal obstruction. Talk to your doctor before taking Neutral-DSR Capsule if you have osteoporosis as Neutral-DSR Capsule may increase the risk of bone fractures on long-term treatment. Consult your doctor before taking Neutral-DSR Capsule if you are pregnant or breastfeeding. Neutral-DSR Capsule may cause dizziness, so drive only if you are alert. Neutral-DSR Capsule should not be given to children as safety has not been established. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Neutral-DSR Capsule is a combination of two drugs: Rabeprazole sodium and Domperidone. Neutral-DSR Capsule is used to treat acidity, heartburn, gastro-oesophageal reflux disease (GERD), Zollinger-Ellison syndrome, nausea, vomiting, the fullness of the stomach, bloating, gas, helicobacter pylori infection, gastric and duodenal ulcers. Rabeprazole sodium is a proton pump inhibitor that works by blocking the action of an enzyme called gastric proton pump, which is responsible for acid production. Domperidone is a dopamine antagonist which works by increasing the movements and contractions of stomach muscles. Together, Neutral-DSR Capsule helps in treating acidity-related problems.

• Dry mouth
• Stomach pain
• Diarrhoea
• Headache
• Flatulence

Do not take Neutral-DSR Capsule if you are allergic to any of its contents; if you are taking atazanavir (used to treat HIV); if you have galactose intolerance, lactase deficiency, glucose-galactose malabsorption, electrolyte disturbance, heart failure, or gastrointestinal haemorrhage. Inform your doctor before taking Neutral-DSR Capsule if you have stomach tumour, kidney, heart or liver disease, or if you are due to have Chromogranin A blood test. On long-term treatment, Neutral-DSR Capsule may cause low magnesium levels, and vitamin B12 levels, and increase the risk of bone fractures; the doctor may advise regular tests for monitoring your condition. Consult your doctor if you are pregnant or breastfeeding. Prolonged intake of Neutral-DSR Capsule is linked with a greater risk of Clostridium difficile-associated diarrhoea, so if you develop diarrhoea that persists or worsens, immediately consult a doctor.

Drug-Drug Interactions: Neutral-DSR Capsule may have interaction with anti-HIV (atazanavir, nelfinavir, saquinavir), blood thinner (clopidogrel, warfarin), a drug used to treat hypothyroidism (levothyroxine), anti-rheumatoid (methotrexate), anti-depressant (duloxetine), vitamin (cyanocobalamin), cardiac glycoside (digoxin).

Drug-Food Interactions: Neutral-DSR Capsule may interact with St.John’s wort (herbal supplement used to treat depression). Avoid alcohol consumption as alcohol intake increases stomach acid production, thereby increasing acidity and heartburn. 

Drug-Disease Interactions: Inform your doctor if you have/had epilepsy, mania, Clostridium difficile-associated diarrhoea (CDAD), liver disease, bone fractures, and hypomagnesemia (low levels of magnesium).

• ATAZANAVIR
• NELFINAVIR
• SAQUINAVIR
• ASPIRIN
• CLOPIDOGREL
• WARFARIN
• LEVOTHYROXINE
• METHOTREXATE
• DULOXETINE
• DIGOXIN
• CYANOCOBALAMIN

• Eat smaller meals more often.
• Avoid smoking and alcohol consumption. Alcohol intake leads to increased production of stomach acid, thereby increasing acidity and heartburn.
• Maintain a healthy weight by regular exercising.
• Avoid lying down after eating as it causes acid reflux.
• Avoid tight-fitting clothes as it might increase the pressure on the abdomen leading to acid reflux.
• Practise relaxation techniques and avoid stress by doing yoga or meditation.
• Avoid foods such as high-fat, spicy, chocolates, citrus fruits, pineapple, tomato, onion, garlic, tea and soda. 
• Avoid sitting continuously as it may trigger acidity. Take a break of 5minutes break every hour by doing brisk walking or stretching.

• Inform your doctor before taking Neutral-DSR Capsule if you are due to have Chromogranin A blood test.
• Neutral-DSR Capsule may cause false-positive results for urine screening tests and secretin stimulation tests. Inform the person doing the tests that you are taking Neutral-DSR Capsule .

Acidity: The stomach is usually protected from acid by a mucous layer. In some cases, the mucous layer gets eroded due to excess acid production, which leads to complications like GERD, heartburn, peptic/gastric ulcers and Zollinger-Ellison syndrome. Gastroesophageal reflux disease (GERD) occurs when stomach acid frequently flows back into the food pipe (oesophagus). This backflow (acid reflux) irritates the food pipe and causes heartburn. Symptoms include heartburn, a sour or bitter taste, and difficulty swallowing. Gastric ulcers are sores that develop on the stomach and intestine lining due to erosion of the stomach's protective lining. Symptoms include nausea, changes in appetite, bloody or dark stools, unexplained weight loss, vomiting, and indigestion. Zollinger-Ellison syndrome is characterised by the formation of tumours in the upper part of the small intestine, which leads to excess acid production. Symptoms include bloating, burping, weight loss, loss of appetite, nausea, and vomiting.