Mofilet-500 Tablet belongs to a class of medications called ‘immunosuppressants’ used to prevent the body from rejecting a transplanted organ such as a kidney, heart or liver. Transplant rejection occurs when the recipient’s immune system identifies the transplanted organ as a ‘foreign object’ and attacks it. If it is not treated promptly, it may cause irreversible damage.

Mofilet-500 Tablet contains ‘Mycophenolate mofetil’ used in the treatment of organ transplant rejection along with another immunosuppressant and anti-inflammatory agent. It inhibits T and B lymphocytes (a type of white blood cell that attacks foreign cells) and suppresses the production of antibodies (identify and kill foreign cells). These effects suppress the immune system so that the transplanted graft is not rejected.

Take Mofilet-500 Tablet as prescribed. Your doctor will advise you on how often you take Mofilet-500 Tablet based on your medical condition. The common side effects of Mofilet-500 Tablet are diarrhoea, vomiting, decreased white blood cells and red blood cell count and infections. Consult your doctor right away if any of these side effects persist or worsen.

Do not take Mofilet-500 Tablet if you are allergic to ‘mycophenolate mofetil’ or any ingredients present in it. Also, do not take it if you are pregnant, planning to become pregnant, or not using effective contraception and breastfeeding. It can cause birth defects/congenital disabilities in the unborn baby, so make sure you take a pregnancy test before using Mofilet-500 Tablet if you are a woman of childbearing potential. You are advised to use effective contraception while taking Mofilet-500 Tablet . It can increase the risk of skin cancer, so wear protective clothing and limit exposure to sunlight. It increases the risk of infections as it can suppress the immune system. Do not donate blood or sperm without informing your doctor. Please do not take any vaccinations as it may be less effective.

Mofilet-500 Tablet contains ‘Mycophenolate mofetil’ which belongs to the class of ‘immunosuppressants’. It is used to prevent organ transplant rejection. It reduces the activity of the immune system by inhibiting the action of white blood cells (responsible for immune reactions) in the body. It is preferred to use over steroids, which have long-term side effects.

• Diarrhoea
• Vomiting
• Infections
• Low white blood cell (WBC) count
• Red blood cell (RBC) count

Before taking Mofilet-500 Tablet , inform your doctor if you have a sign of infection such as a fever or sore throat, have any unexpected bruising or bleeding, have a history of digestive system problems such as a stomach ulcer, are planning to become pregnant, get pregnant while taking Mofilet-500 Tablet , and have rare hereditary disorders such as Lesch-Nyhan or Kelley-Seegmiller syndrome (conditions caused by a deficiency of the enzyme hypoxanthine-guanine phosphoribosyl-transferase (HGPRT)). Limit your exposure to sunlight as Mofilet-500 Tablet increases the risk of skin cancer. Do not donate blood while taking Mofilet-500 Tablet and for at least 60 days after discontinuing the therapy. Men should not donate sperm while taking Mofilet-500 Tablet for at least 90 days after discontinuing the therapy. Please do not take any vaccinations (live vaccine) as it will not be much effective. The oral suspension contains aspartame (sweetener and a phenylalanine source), so it should be used with caution in patients with phenylketonuria (a birth defect/congenital disability that causes decreased metabolism of phenylalanine).

Drug-Drug interactions: Mofilet-500 Tablet may interact with an immunosuppressant (azathioprine), antiviral medications (aciclovir and ganciclovir), a medication used to treat tuberculosis (rifampicin), antacids such as proton pump inhibitors, medications used to treat chronic kidney failure such as phosphate binders, and an antibiotic (norfloxacin+metronidazole).

Drug-Dood interactions: Avoid alcohol consumption as it may worsen the condition by increasing the risk of side effects.

Drug-Disease interactions: Mofilet-500 Tablet should be used with caution in patients with liver or kidney disease, stomach ulcers, chronic infections and phenylketonuria.

• AZATHIOPRINE
• ACICLOVIR
• GANCICLOVIR
• RIFAMPICIN
• NORFLOXACIN+METRONIDAZOLE

• Eat a well-balanced and healthy diet as it helps you to recover quickly. A dietitian will help you to create a diet plan based on your health condition. 

• Avoid eating raw or undercooked food. 

• Protect yourself from exposure to sunlight and soil. Wear a long-sleeve shirt, hat, long pants and shoes while going outdoors. Also, wear sunscreen with high SPF. 

• Stay away from people who are sick. 

• Limit alcohol consumption and quit smoking. 

• Talk with your doctor at least 2 months before leaving, if you plan to travel, especially to developing countries. 

• Your doctor may advise you to take regular blood tests to monitor blood cell counts and liver function. In general, the tests are done every 2 to 4 weeks in the initial two months, followed by once every 2 to 3 months.

• Do not have immunizations/vaccinations without the consent of your doctor. Avoid contact with people who have recently received live vaccines (such as flu vaccine inhaled through the nose).

Organ transplant rejection: When you get a new organ transplanted to your body, your body recognizes it as a foreign element and tries to attack and reject it because it is not originally part of your body. So, immunosuppressant drugs are given to such patients to suppress your immune system, stopping it from attacking the newly transplanted organs. Warnings signs of rejection are flu-like symptoms such as chills, headache, nausea, or vomiting, fever higher than 100o F, newly found pain at the region of the transplanted organ, weight gain and fatigue.