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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Jbmune 500 Tablet is used to prevent the body from rejecting a transplanted organ such as a kidney, heart or liver. It contains Mycophenolate mofetil, which is used along with another immunosuppressant and anti-inflammatory agent. It inhibits T and B lymphocytes (type of white blood cells that attack foreign cells) and suppresses the production of antibodies (identify and kill foreign cells). These effects suppress the immune system so that the transplanted graft is not rejected. It may cause common side effects such as diarrhoea, vomiting, decreased white blood cells and red blood cell count and infections. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Jbmune 500 Tablet

Jbmune 500 Tablet belongs to a class of medications called ‘immunosuppressants’ used to prevent the body from rejecting a transplanted organ such as a kidney, heart or liver. Transplant rejection occurs when the recipient’s immune system identifies the transplanted organ as a ‘foreign object’ and attacks it. If it is not treated promptly, it may cause irreversible damage.

Jbmune 500 Tablet contains ‘Mycophenolate mofetil’ used in the treatment of organ transplant rejection along with another immunosuppressant and anti-inflammatory agent. It inhibits T and B lymphocytes (a type of white blood cell that attacks foreign cells) and suppresses the production of antibodies (identify and kill foreign cells). These effects suppress the immune system so that the transplanted graft is not rejected.

Take Jbmune 500 Tablet as prescribed. Your doctor will advise you on how often you take Jbmune 500 Tablet based on your medical condition. The common side effects of Jbmune 500 Tablet are diarrhoea, vomiting, decreased white blood cells and red blood cell count and infections. Consult your doctor right away if any of these side effects persist or worsen.

Do not take Jbmune 500 Tablet if you are allergic to ‘mycophenolate mofetil’ or any ingredients present in it. Also, do not take it if you are pregnant, planning to become pregnant, or not using effective contraception and breastfeeding. It can cause birth defects/congenital disabilities in the unborn baby, so make sure you take a pregnancy test before using Jbmune 500 Tablet if you are a woman of childbearing potential. You are advised to use effective contraception while taking Jbmune 500 Tablet . It can increase the risk of skin cancer, so wear protective clothing and limit exposure to sunlight. It increases the risk of infections as it can suppress the immune system. Do not donate blood or sperm without informing your doctor. Please do not take any vaccinations as it may be less effective.

Uses of Jbmune 500 Tablet

Prevent organ transplant rejection.

Directions for Use

Tablet: Take it as advised by the doctor. Swallow it as a whole with a glass of water. Do not break, crush or chew it. Suspension: It is available as a dry powder and mixed with the liquid (mostly boiled and cooled water) up to the mark. Shake the bottle well before each use and take the dose as prescribed.

Medicinal Benefits

Jbmune 500 Tablet contains ‘Mycophenolate mofetil’ which belongs to the class of ‘immunosuppressants’. It is used to prevent organ transplant rejection. It reduces the activity of the immune system by inhibiting the action of white blood cells (responsible for immune reactions) in the body. It is preferred to use over steroids, which have long-term side effects.

How Jbmune 500 Tablet Works

Jbmune 500 Tablet contains ‘Mycophenolate mofetil’ used in the treatment of organ transplant rejection along with another immunosuppressant and anti-inflammatory agent. It inhibits T and B lymphocytes (a type of white blood cell that attacks foreign cells) and suppresses the production of antibodies (identify and kill foreign cells). These effects suppress the immune system so that the transplanted graft is not rejected.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Jbmune 500 Tablet

  • Diarrhoea
  • Vomiting
  • Infections
  • Low white blood cell (WBC) count
  • Red blood cell (RBC) count

What if I have taken an overdose of Jbmune 500 Tablet

Do not take more than the prescribed dose of Jbmune 500 Tablet as it may cause overdose. The symptoms of overdose include nausea, vomiting, stomach pain, diarrhoea, heartburn, fever, chills or sore throat. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Before taking Jbmune 500 Tablet , inform your doctor if you have a sign of infection such as a fever or sore throat, have any unexpected bruising or bleeding, have a history of digestive system problems such as a stomach ulcer, are planning to become pregnant, get pregnant while taking Jbmune 500 Tablet , and have rare hereditary disorders such as Lesch-Nyhan or Kelley-Seegmiller syndrome (conditions caused by a deficiency of the enzyme hypoxanthine-guanine phosphoribosyl-transferase (HGPRT)). Limit your exposure to sunlight as Jbmune 500 Tablet increases the risk of skin cancer. Do not donate blood while taking Jbmune 500 Tablet and for at least 60 days after discontinuing the therapy. Men should not donate sperm while taking Jbmune 500 Tablet for at least 90 days after discontinuing the therapy. Please do not take any vaccinations (live vaccine) as it will not be much effective. The oral suspension contains aspartame (sweetener and a phenylalanine source), so it should be used with caution in patients with phenylketonuria (a birth defect/congenital disability that causes decreased metabolism of phenylalanine).

Drug-Drug Interactions

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Mycophenolate MofetilDrospirenone
Severe
Mycophenolate MofetilCholestyramine
Severe

Drug-Drug Interactions

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Mycophenolate MofetilDrospirenone
Severe
How does the drug interact with Jbmune 500 Tablet 10's:
Combining Drospirenone and Jbmune 500 Tablet 10's can increase the risk of developing serious infections.

How to manage the interaction:
Although taking Jbmune 500 Tablet 10's and Drospirenone together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination call a doctor right away. Do not discontinue any medications without consulting a doctor.
Mycophenolate MofetilCholestyramine
Severe
How does the drug interact with Jbmune 500 Tablet 10's:
Co-administration of cholestyramine and Jbmune 500 Tablet 10's may interfere with the action of Jbmune 500 Tablet 10's.

How to manage the interaction:
Although taking cholestyramine and Jbmune 500 Tablet 10's together can result in an interaction, they can be taken together if prescribed by a doctor. Do not stop using any medications without consulting a doctor.
Mycophenolate MofetilCertolizumab
Severe
How does the drug interact with Jbmune 500 Tablet 10's:
Combining Certolizumab and Jbmune 500 Tablet 10's can increase the risk of developing serious infections.

How to manage the interaction:
Although taking Jbmune 500 Tablet 10's and Certolizumab together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination call a doctor right away. Do not discontinue any medications without consulting a doctor.
Mycophenolate MofetilDeferiprone
Severe
How does the drug interact with Jbmune 500 Tablet 10's:
Combining Deferiprone and Jbmune 500 Tablet 10's can increase the risk of developing serious infections.

How to manage the interaction:
Although taking Jbmune 500 Tablet 10's and Deferiprone together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination call a doctor right away. Do not discontinue any medications without consulting a doctor.
Mycophenolate MofetilColestyramine
Severe
How does the drug interact with Jbmune 500 Tablet 10's:
Coadministration of Jbmune 500 Tablet 10's and Colestyramine may decrease the blood levels of Jbmune 500 Tablet 10's.

How to manage the interaction:
Although taking Cholestyramine and Jbmune 500 Tablet 10's together can result in an interaction, they can be taken together if prescribed by a doctor. However, if you experience Constipation, Diarrhea, Stomach pain, Nausea, or Loss of appetite, consult a doctor. Do not stop using any medications without consulting a doctor.
Mycophenolate MofetilInfliximab
Severe
How does the drug interact with Jbmune 500 Tablet 10's:
Combining Infliximab and Jbmune 500 Tablet 10's can increase the risk of developing serious infections.

How to manage the interaction:
Although taking Jbmune 500 Tablet 10's and Infliximab together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination call a doctor right away. Do not discontinue any medications without consulting a doctor.
Mycophenolate MofetilMedicinal charcoal
Severe
How does the drug interact with Jbmune 500 Tablet 10's:
Taking Jbmune 500 Tablet 10's and Medicinal charcoal may decrease the blood levels of Jbmune 500 Tablet 10's.

How to manage the interaction:
Taking Medicinal charcoal with Jbmune 500 Tablet 10's together can possibly result in an interaction, it can be taken if a doctor has advised it. However, if you notice any unusual symptoms, you should consult a doctor immediately. Do not stop using any medications without consulting a doctor.
Mycophenolate MofetilEtanercept
Severe
How does the drug interact with Jbmune 500 Tablet 10's:
Using etanercept together with Jbmune 500 Tablet 10's may increase the risk of developing serious infections.

How to manage the interaction:
Although taking Jbmune 500 Tablet 10's and Etanercept together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination consult a doctor right away. Do not discontinue any medications without consulting a doctor.
Mycophenolate MofetilVoclosporin
Severe
How does the drug interact with Jbmune 500 Tablet 10's:
Using voclosporin together with Jbmune 500 Tablet 10's may increase the risk of serious infections.

How to manage the interaction:
Although taking Jbmune 500 Tablet 10's and Voclosporin together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination call a doctor right away. Do not discontinue any medications without consulting a doctor.
Mycophenolate MofetilBaricitinib
Severe
How does the drug interact with Jbmune 500 Tablet 10's:
Combining Baricitinib and Jbmune 500 Tablet 10's can increase the risk of developing serious infections.

How to manage the interaction:
Although there is an interaction, Baricitinib can be taken with Jbmune 500 Tablet 10's if prescribed by the doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a well-balanced and healthy diet as it helps you to recover quickly. A dietitian will help you to create a diet plan based on your health condition. 

  • Avoid eating raw or undercooked food. 

  • Protect yourself from exposure to sunlight and soil. Wear a long-sleeve shirt, hat, long pants and shoes while going outdoors. Also, wear sunscreen with high SPF. 

  • Stay away from people who are sick. 

  • Limit alcohol consumption and quit smoking. 

  • Talk with your doctor at least 2 months before leaving, if you plan to travel, especially to developing countries. 

Habit Forming

No

Therapeutic Class

IMMUNOSUPPRESSANTS

Jbmune 500 Tablet Substitute

Substitutes safety advice
  • Cellcept 500 mg Tablet 10's

    69.57per tablet
  • Mmf Tablet 10's

    70.47per tablet
  • Mycept 500 Tablet 10's

    67.60per tablet
  • Seromune 500 Tablet 10's

    54.36per tablet
  • Immutil 500 mg Tablet 10's

    69.66per tablet
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Alcohol

Caution

Consumption of alcohol may worsen the condition by increasing the risk of side-effects.

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Pregnancy

Unsafe

Jbmune 500 Tablet is a pregnancy category D drug. It causes birth defects in the fetus. So, it is not recommended for use in pregnant women.

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Breast Feeding

Unsafe

Jbmune 500 Tablet is not recommended for breastfeeding mothers as it may be excreted in the breast milk. However, your doctor may prescribe Jbmune 500 Tablet if the benefits outweigh the risks.

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Driving

Safe if prescribed

Jbmune 500 Tablet may not affect your ability to drive. However, ask your doctor's advice, whether it is safe to drive based on your health conditions.

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Liver

Caution

Jbmune 500 Tablet should be used with caution in patients with liver diseases. Dose adjustments may be necessary.

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Kidney

Caution

Jbmune 500 Tablet should be used with caution in patients with kidney diseases. Dose adjustments may be necessary.

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Children

Caution

Jbmune 500 Tablet should be used with caution in children below 12 years of age. Dose adjustments may be necessary.

FAQs

Jbmune 500 Tablet is used to prevent the body from rejecting a transplanted organ such as a kidney, heart or liver.
Jbmune 500 Tablet belongs to the group of medications called ‘immunosuppressants’. It works by weakening the immune system by inhibiting the production of cells or antibodies that attack foreign cells. This effect helps in stopping the immune system from targeting and rejecting the transplanted organ.
Jbmune 500 Tablet can suppress the immune system and can increase the risk of skin cancer. So, you should avoid prolonged exposure to sunlight. Also, wear protective clothing covering your head, neck, arms and legs, and use a sunscreen lotion with a high SPF (sun protection factor).
Jbmune 500 Tablet can suppress the immune system. So, you should not donate blood while using Jbmune 500 Tablet and at least 60 days after stopping treatment as it makes you more prone to infections. Besides, men should not donate sperm while using Jbmune 500 Tablet for at least 90 days after stopping the treatment.
It is not advised to get pregnant while using Jbmune 500 Tablet as it may cause birth defects/congenital disabilities in the unborn baby. So, it would help if you took an effective and reliable contraceptive while using Jbmune 500 Tablet , even when men are taking Jbmune 500 Tablet .
Jbmune 500 Tablet is given to stop rejection of the transplanted organ. If you abruptly stop taking this drug, it might result in rejecting the transplanted organ. So, check with your doctor if you want to stop using Jbmune 500 Tablet .
Jbmune 500 Tablet may increase the risk of skin cancer as it reduces the body’s defences. Limit the amount of sunlight and UV light, wear protective clothing and use sunscreen with high SPF.
Your doctor has prescribed Jbmune 500 Tablet to suppress the immunity and prevent the rejection of the transplanted kidney.
Jbmune 500 Tablet is not a steroid or chemotherapy medicine. It is an immunosuppressant used to prevent organ rejection after a transplant.
Jbmune 500 Tablet may cause skin problems such as hair loss. Talk to the doctor if you have any concerns.
The doctor may recommend regular blood tests to check for signs of infection and blood count. Women of childbearing potential must provide a negative pregnancy test before the start of treatment.
As Jbmune 500 Tablet reduces the body’s defences, you may be at a higher risk of developing infections. Therefore, your doctor has asked you to stay away from a person who has chickenpox or shingles.
Jbmune 500 Tablet causes a high frequency of miscarriage and birth defects. Therefore, before the start of treatment, women of childbearing potential must provide a negative pregnancy test. Also, women who can become pregnant should use effective contraception during treatment and for 6 months after stopping Jbmune 500 Tablet . Two forms of contraception are preferable as this will reduce the risk of unintended pregnancy. Contact the doctor about the effective methods of contraception.
As a precaution, the male or his female partner must use reliable contraception during treatment and for 90 days after stopping Jbmune 500 Tablet .
The common side effects of Jbmune 500 Tablet are diarrhoea, vomiting, decreased white blood cells and red blood cell count and infections. Consult your doctor right away if any of these side effects persist or worsen.

Country of origin

India

Manufacturer/Marketer address

Cnergy It Park, 3Rd Floor Appa Saheb Marathe Marg, Prabhadevi, Mumbai 400025.
Other Info - JBM0001

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