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Written By Veda Maddala , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Mixtard 50 HM 100IU/ml Penfill 5 x 3 ml is used in the treatment of type 1 and 2 diabetes mellitus. This medicine works by suppressing the production of sugar in the liver and facilitates the reuptake of sugar in the fat and muscle cells, thereby maintaining consistent sugar control. Common side effects include low blood sugar, swelling in your hands or feet, weight gain, or thickening of the skin at the injection site.
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Manufacturer/Marketer :

Novo Nordisk India Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Mixtard 50 HM 100IU/ml Penfill 5 x 3 ml

Mixtard 50 HM 100IU/ml Penfill 5 x 3 ml is used for the treatment of both type 1 and type 2 diabetes mellitus. Diabetes mellitus is a condition that affects the way the body processes glucose. In Diabetes Mellitus Type 1, the body does not make enough insulin to control blood sugar levels. In Diabetes Mellitus type 2, either the body stops producing enough insulin (the hormone which helps to decrease sugar levels in the blood), or there is resistance to the action of insulin. As a result, insulin is produced in large amounts, but it cannot act on the organs of the body.

Mixtard 50 HM 100IU/ml Penfill 5 x 3 ml is a combination of two drugs: Human insulin (a short-acting type of insulin) and Insulin isophane (intermediate-acting). Mixtard 50 HM 100IU/ml Penfill 5 x 3 ml suppresses the production of sugar in the liver and facilitates the reuptake of sugar in the fat and muscle cells; thereby, Mixtard 50 HM 100IU/ml Penfill 5 x 3 ml ensures rapid and consistent sugar control. 

 Take Mixtard 50 HM 100IU/ml Penfill 5 x 3 ml as advised by your doctor. If you are not well trained to self-administer Mixtard 50 HM 100IU/ml Penfill 5 x 3 ml, ask your healthcare professional to administer it. In some cases, Mixtard 50 HM 100IU/ml Penfill 5 x 3 ml may cause certain common side effects like an allergic reaction at the site of injection, hypoglycemia (low blood glucose level), itching, lipodystrophy (skin thickening or pits at the injection site), oedema (swelling), rashes, and weight gain. Most of these side effects of Mixtard 50 HM 100IU/ml Penfill 5 x 3 ml do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Consult your doctor before taking Mixtard 50 HM 100IU/ml Penfill 5 x 3 ml if you are pregnant or breastfeeding. Mixtard 50 HM 100IU/ml Penfill 5 x 3 ml may cause drowsiness, so drive with caution. Avoid alcohol consumption along with Mixtard 50 HM 100IU/ml Penfill 5 x 3 ml as it may cause unpleasant side effects. Mixtard 50 HM 100IU/ml Penfill 5 x 3 ml should be given to children only if prescribed by the doctor. Keep your doctor informed about your health condition and medications to rule out any interactions. Mixtard 50 HM 100IU/ml Penfill 5 x 3 ml is a cold chain medicine, it has to be stored in the refrigerator between 2-8°C else its efficiency may be lost. Do not store in the freezer.

Uses of Mixtard 50 HM 100IU/ml Penfill 5 x 3 ml

Treatment of Diabetes (Type 1 diabetes mellitus, Type 2 diabetes mellitus)

Directions for Use

Mixtard 50 HM 100IU/ml Penfill 5 x 3 ml should be administered subcutaneously (in the upper thigh, abdomen, upper arm, or buttocks). It should never be administered intravenously or in the vein. If you are not well trained to self-administer Mixtard 50 HM 100IU/ml Penfill 5 x 3 ml, ask your healthcare professional to administer it.

Medicinal Benefits

Mixtard 50 HM 100IU/ml Penfill 5 x 3 ml is a combination of two drugs: Human insulin (a short-acting type of insulin) and Insulin isophane (intermediate-acting). Mixtard 50 HM 100IU/ml Penfill 5 x 3 ml is used for the treatment of both type 1 and type 2 diabetes mellitus. Mixtard 50 HM 100IU/ml Penfill 5 x 3 ml suppresses the production of sugar in the liver and facilitates the reuptake of sugar in the fat and muscle cells; thereby, Mixtard 50 HM 100IU/ml Penfill 5 x 3 ml ensures rapid and consistent sugar control.  Mixtard 50 HM 100IU/ml Penfill 5 x 3 ml helps in improving glycaemic control, which in turn decreases the risk of progression of diabetes complications like damage to the retina (retinopathy), damage to the kidney (nephropathy), damage of nerve cells (neuropathy), delayed wound healing, diabetic foot ulcer.

How Mixtard 50 HM 100IU/ml Penfill 5 x 3 ml Works

Mixtard 50 HM 100IU/ml Penfill 5 x 3 ml is a combination of two drugs: Human insulin (a short-acting type of insulin) and Insulin isophane (intermediate-acting). Mixtard 50 HM 100IU/ml Penfill 5 x 3 ml suppresses the production of sugar in the liver and facilitates the reuptake of sugar in the fat and muscle cells; thereby, Mixtard 50 HM 100IU/ml Penfill 5 x 3 ml ensures rapid and consistent sugar control.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Mixtard 50 HM 100IU/ml Penfill 5 x 3 ml

  • Allergic reaction at the site of injection

  • Hypoglycemia (low blood glucose level)

  • Itching

  • Lipodystrophy (skin thickening or pits at the injection site)

  • Oedema (swelling)

  • Rashes

  • Weight gain

What if I have taken an overdose of Mixtard 50 HM 100IU/ml Penfill 5 x 3 ml

Never take more than the prescribed dose. Overdose of Mixtard 50 HM 100IU/ml Penfill 5 x 3 ml may cause cold sweats, trembling hands, intense anxiety, and a general sense of confusion. Seek immediate medical help if you suspect that you might have taken an overdose.

Drug Warnings

Do not take Mixtard 50 HM 100IU/ml Penfill 5 x 3 ml if you are allergic to any of the contents. Inform your doctor if you have hypoglycemia (low blood glucose levels), hypokalemia (low levels of potassium in the blood), heart, kidney or liver problems. Consult a doctor before taking Mixtard 50 HM 100IU/ml Penfill 5 x 3 ml if you are pregnant or breastfeeding. Mixtard 50 HM 100IU/ml Penfill 5 x 3 ml may cause dizziness, so drive only if you are alert. You are recommended not to consume alcohol as it may cause unpleasant side effects. Care should be taken when you are travelling across more than 2 time zones; your doctor may adjust your insulin schedule. 

Drug-Drug Interactions

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INSULIN HUMANGatifloxacin
Critical
Isophane InsulinGemifloxacin
Severe

Drug-Drug Interactions

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INSULIN HUMANGatifloxacin
Critical
How does the drug interact with Mixtard 50 HM 100IU/ml Penfill 5 x 3 ml:
Coadministration of Gatifloxacin with Mixtard 50 HM 100IU/ml Penfill 5 x 3 ml may sometimes affect blood glucose levels. Both low blood glucose and, less frequently, high blood glucose have been reported.

How to manage the interaction:
Although there is a possible interaction, Mixtard 50 HM 100IU/ml Penfill 5 x 3 ml can be taken with Gatifloxacin if prescribed by the doctor. Consult the prescriber if you experience symptoms such as nervousness, confusion, headache, dizziness, drowsiness, tremors, nausea, hunger, weakness, perspiration, palpitation, rapid heartbeat, increased urination, increased thirst, and increased hunger. Maintaining blood glucose levels is advised.
Isophane InsulinGemifloxacin
Severe
How does the drug interact with Mixtard 50 HM 100IU/ml Penfill 5 x 3 ml:
Taking Mixtard 50 HM 100IU/ml Penfill 5 x 3 ml with gemifloxacin affects blood glucose levels, which may cause hyperglycemia (high blood sugar) and hypoglycemia (low blood sugar) less frequently.

How to manage the interaction:
Although taking Gemifloxacin and Mixtard 50 HM 100IU/ml Penfill 5 x 3 ml together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience hypoglycemia or hyperglycemia. Symptoms of hypoglycemia include headache, dizziness, drowsiness, nervousness, confusion, shaking, nausea, loss of hunger, weakness, sweating, palpitations, and rapid heartbeat. Symptoms of hyperglycemia may include increased thirst, increased hunger, and increased urination. Do not stop using any medications without first talking to your doctor.
Isophane InsulinCinoxacin
Severe
How does the drug interact with Mixtard 50 HM 100IU/ml Penfill 5 x 3 ml:
Taking Mixtard 50 HM 100IU/ml Penfill 5 x 3 ml with cinoxacin affects blood glucose levels, which may cause hyperglycemia (high blood sugar) and hypoglycemia (low blood sugar) less frequently.

How to manage the interaction:
Although taking Cinoxacin and Mixtard 50 HM 100IU/ml Penfill 5 x 3 ml together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience hypoglycemia or hyperglycemia. Symptoms of hypoglycemia include headache, dizziness, drowsiness, nervousness, confusion, shaking, nausea, loss of hunger, weakness, sweating, palpitations, and rapid heartbeat. Symptoms of hyperglycemia may include increased thirst, increased hunger, and increased urination. Do not stop using any medications without first talking to your doctor.
Isophane InsulinTrovafloxacin
Severe
How does the drug interact with Mixtard 50 HM 100IU/ml Penfill 5 x 3 ml:
Taking Mixtard 50 HM 100IU/ml Penfill 5 x 3 ml with trovafloxacin affects blood glucose levels, which may cause hyperglycemia (high blood sugar) and hypoglycemia (low blood sugar) less frequently.

How to manage the interaction:
Although taking trovafloxacin and Mixtard 50 HM 100IU/ml Penfill 5 x 3 ml together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience hypoglycemia or hyperglycemia. Symptoms of hypoglycemia include headache, dizziness, drowsiness, nervousness, confusion, shaking, nausea, loss of hunger, weakness, sweating, palpitations, and rapid heartbeat. Symptoms of hyperglycemia may include increased thirst, increased hunger, and increased urination. Do not stop using any medications without first talking to your doctor.
Isophane InsulinNalidixic acid
Severe
How does the drug interact with Mixtard 50 HM 100IU/ml Penfill 5 x 3 ml:
Taking Mixtard 50 HM 100IU/ml Penfill 5 x 3 ml with nalidixic acid affects blood glucose levels, which may cause hyperglycemia (high blood sugar) and hypoglycemia (low blood sugar) less frequently.

How to manage the interaction:
Although taking Nalidixic acid and Mixtard 50 HM 100IU/ml Penfill 5 x 3 ml together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience hypoglycemia or hyperglycemia. Symptoms of hypoglycemia include headache, dizziness, drowsiness, nervousness, confusion, shaking, nausea, loss of hunger, weakness, sweating, palpitations, and rapid heartbeat. Symptoms of hyperglycemia may include increased thirst, increased hunger, and increased urination. Do not stop using any medications without first talking to your doctor.
Isophane InsulinEnoxacin
Severe
How does the drug interact with Mixtard 50 HM 100IU/ml Penfill 5 x 3 ml:
Taking Mixtard 50 HM 100IU/ml Penfill 5 x 3 ml with enoxacin affects blood glucose levels, which may cause hyperglycemia (high blood sugar) and hypoglycemia (low blood sugar) less frequently.

How to manage the interaction:
Although taking Enoxacin and Mixtard 50 HM 100IU/ml Penfill 5 x 3 ml together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience hypoglycemia or hyperglycemia. Symptoms of hypoglycemia include headache, dizziness, drowsiness, nervousness, confusion, shaking, nausea, loss of hunger, weakness, sweating, palpitations, and rapid heartbeat. Symptoms of hyperglycemia may include increased thirst, increased hunger, and increased urination. Do not stop using any medications without first talking to your doctor.
Isophane InsulinCiprofloxacin
Severe
How does the drug interact with Mixtard 50 HM 100IU/ml Penfill 5 x 3 ml:
Taking Mixtard 50 HM 100IU/ml Penfill 5 x 3 ml with ciprofloxacin effects blood glucose levels, which may cause hyperglycemia (high blood sugar) and hypoglycemia (low blood sugar) less frequently..

How to manage the interaction:
Although taking ciprofloxacin and Mixtard 50 HM 100IU/ml Penfill 5 x 3 ml together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience headache, dizziness, drowsiness, nervousness, confusion, shaking, nausea, loss of hunger, weakness, sweating, and rapid heartbeat, increased thirst, increased hunger, and increased urination. Do not stop using any medications without talking to a doctor.
INSULIN HUMANCiprofloxacin
Severe
How does the drug interact with Mixtard 50 HM 100IU/ml Penfill 5 x 3 ml:
Taking Mixtard 50 HM 100IU/ml Penfill 5 x 3 ml with ciprofloxacin effects blood glucose levels, which may cause hyperglycemia (high blood sugar) or hypoglycemia (low blood sugar) less frequently.

How to manage the interaction:
Although taking ciprofloxacin and Mixtard 50 HM 100IU/ml Penfill 5 x 3 ml together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult a doctor if you experience headaches, dizziness, sleepiness, anxiety, disorientation, tremors, nausea, hunger, weakness, increased sweating, and a rapid heartbeat, increased hunger, increased thirst. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Include foods rich in healthy carbohydrates and fiber, fruits, whole grains, and vegetables in your diet.
  • Try eating food at regular intervals. Do not skip meals. Also, try not to overeat.
  • Follow a healthy diet and walk for at least a few minutes to complement treatment with Mixtard 50 HM 100IU/ml Penfill 5 x 3 ml.
  • Maintain a healthy weight by exercising regularly.
  • Rest properly, and avoid stress by doing meditation or yoga.

Habit Forming

No

Therapeutic Class

ANTIDIABETICS

Mixtard 50 HM 100IU/ml Penfill 5 x 3 ml Substitute

Substitutes safety advice
  • Human Mixtard 50 40IU/ml Injection 10 ml

    26.28per tablet
  • Lupisulin M 50 100IU/ml Cartridge 3 ml

    110.40per tablet
  • Huminsulin 50/50 40IU/ml Injection 10 ml

    16.81per tablet
  • New Wosulin 50/50 100Iu Injection 3 ml

    232.20per tablet
  • Wosulin 50/50 40IU Injection 15 ml

    by AYUR

    13.77per tablet
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Alcohol

Unsafe

You are recommended not to consume alcohol along with Mixtard 50 HM 100IU/ml Penfill 5 x 3 ml to avoid unpleasant side effects. Alcohol may cause increased drowsiness.

bannner image

Pregnancy

Safe if prescribed

It is safe to use Mixtard 50 HM 100IU/ml Penfill 5 x 3 ml during pregnancy if prescribed by the doctor. However, consult your doctor if you have any concerns regarding this.

bannner image

Breast Feeding

Safe if prescribed

It is safe to use Mixtard 50 HM 100IU/ml Penfill 5 x 3 ml by breastfeeding mothers if prescribed by the doctor. However, consult your doctor if you have any concerns regarding this.

bannner image

Driving

Caution

Mixtard 50 HM 100IU/ml Penfill 5 x 3 ml may cause drowsiness and hypoglycemia (low blood sugar). Therefore, drive only if you are alert.

bannner image

Liver

Caution

Mixtard 50 HM 100IU/ml Penfill 5 x 3 ml should be taken with caution, especially if you have a history of liver disease. The dose may have to be adjusted by your doctor.

bannner image

Kidney

Caution

Mixtard 50 HM 100IU/ml Penfill 5 x 3 ml should be taken with caution, especially if you have a history of kidney disease. The dose may have to be adjusted by your doctor.

bannner image

Children

Safe if prescribed

Mixtard 50 HM 100IU/ml Penfill 5 x 3 ml can be given safely to children provided the dose has been prescribed by a child specialist.

FAQs

Mixtard 50 HM 100IU/ml Penfill 5 x 3 ml is used for the treatment of both type 1 and type 2 diabetes mellitus.
Mixtard 50 HM 100IU/ml Penfill 5 x 3 ml suppresses the production of sugar in the liver and facilitates the reuptake of sugar in the fat and muscle cells, thereby Mixtard 50 HM 100IU/ml Penfill 5 x 3 ml ensures rapid and consistent sugar control.Â
Mixtard 50 HM 100IU/ml Penfill 5 x 3 ml may sometimes lower the blood glucose levels more than normal, leading to hypoglycaemia. Regularly monitor your blood sugar levels while taking Mixtard 50 HM 100IU/ml Penfill 5 x 3 ml. Hypoglycaemia symptoms include headache, drowsiness, cold sweat, feeling sick, unusual tiredness or weakness, and visual disturbances.
Do not stop taking Mixtard 50 HM 100IU/ml Penfill 5 x 3 ml without consulting your doctor on your own as it may cause an increase in blood glucose levels. Continue taking Mixtard 50 HM 100IU/ml Penfill 5 x 3 ml for as long as your doctor has prescribed it to you. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Mixtard 50 HM 100IU/ml Penfill 5 x 3 ml.
Maintain a healthy diet by regular intake of carbohydrates such as bread and products containing starch and sugar. Eat your meals regularly, and do not exercise heavily for longer durations with an empty stomach.
Hypoglycaemia may occur following prolonged or severe exercise, during illness, alcohol consumption, low food intake, or when Mixtard 50 HM 100IU/ml Penfill 5 x 3 ml is taken along with other antidiabetic medicines.
Side effects of Mixtard 50 HM 100IU/ml Penfill 5 x 3 ml include allergic reaction at the site of injection, hypoglycemia (low blood glucose level), itching, lipodystrophy (skin thickening or pits at the injection site), oedema (swelling), rashes, and weight gain. Most of these side effects may not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.
Cut back on foods high in sodium, alcohol, fried foods, and high-carb food and drinks like sugary drinks, drinks with added sugar, white rice and starchy vegetables.
The injection site should be changed to prevent skin changes like lumps under the skin. Mixtard 50 HM 100IU/ml Penfill 5 x 3 ml may not work well if injected into the lumpy area.
Maintain a healthy diet and exercise regularly. Limit sugar intake and avoid smoking & alcohol consumption. Manage stress by doing meditation or yoga.
Hypoglycaemia (low blood sugar) may occur because you inject too much insulin, miss or delay meals, do not eat enough, eat food containing less carbohydrate than normal, drink alcohol, lose carbohydrates due to vomiting or diarrhoea, do more exercise than usual or a different type of physical activity, are recovering from an injury, illness, operation or stress, or are taking/have stopped taking other medicines.
Symptoms of high blood sugar include feeling thirsty, increased urination, weakness or tiredness, blurred vision and weight loss.
Mixtard 50 HM 100IU/ml Penfill 5 x 3 ml is to be injected below the skin (subcutaneously). The best areas to inject Mixtard 50 HM 100IU/ml Penfill 5 x 3 ml are on your stomach, upper arm, upper thigh, or buttocks.
Unopened vials are to be refrigerated between 2°C and 8°C. Opened vials (in-use) may be stored not above 25ºC for a maximum of 4 weeks. The used needle should be placed in a puncture-resistant disposable container and disposed of properly as directed by your healthcare provider.
Avoid drinking alcohol while taking Mixtard 50 HM 100IU/ml Penfill 5 x 3 ml as it might lower blood sugar levels and cause hypoglycaemia.

Country of origin

India

Manufacturer/Marketer address

16th Floor, Godrej BKC, Plot – C, “G” Block, Bandra-Kurla Complex, Bandra (East), Mumbai – 400 051, India
Other Info - MIX0002

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