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Written By Veda Maddala , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Last Updated Oct 9, 2024 | 12:37 PM IST
Human Mixtard 50 40IU/ml Injection is used in the treatment of type 1 and 2 diabetes mellitus. This medicine works by suppressing the production of sugar in the liver and facilitates the reuptake of sugar in the fat and muscle cells, thereby maintaining consistent sugar control. Common side effects include low blood sugar, swelling in your hands or feet, weight gain, or thickening of the skin at the injection site.
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Manufacturer/Marketer

Novo Nordisk India Pvt Ltd

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Human Mixtard 50 40IU/ml Injection

Human Mixtard 50 40IU/ml Injection is used for the treatment of both type 1 and type 2 diabetes mellitus. Diabetes mellitus is a condition that affects the way the body processes glucose. In Diabetes Mellitus Type 1, the body does not make enough insulin to control blood sugar levels. In Diabetes Mellitus type 2, either the body stops producing enough insulin (the hormone which helps to decrease sugar levels in the blood), or there is resistance to the action of insulin. As a result, insulin is produced in large amounts, but it cannot act on the organs of the body.

Human Mixtard 50 40IU/ml Injection is a combination of two drugs: Human insulin (a short-acting type of insulin) and Insulin isophane (intermediate-acting). Human Mixtard 50 40IU/ml Injection suppresses the production of sugar in the liver and facilitates the reuptake of sugar in the fat and muscle cells; thereby, Human Mixtard 50 40IU/ml Injection ensures rapid and consistent sugar control. 

 Take Human Mixtard 50 40IU/ml Injection as advised by your doctor. If you are not well trained to self-administer Human Mixtard 50 40IU/ml Injection, ask your healthcare professional to administer it. In some cases, Human Mixtard 50 40IU/ml Injection may cause certain common side effects like an allergic reaction at the site of injection, hypoglycemia (low blood glucose level), itching, lipodystrophy (skin thickening or pits at the injection site), oedema (swelling), rashes, and weight gain. Most of these side effects of Human Mixtard 50 40IU/ml Injection do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Consult your doctor before taking Human Mixtard 50 40IU/ml Injection if you are pregnant or breastfeeding. Human Mixtard 50 40IU/ml Injection may cause drowsiness, so drive with caution. Avoid alcohol consumption along with Human Mixtard 50 40IU/ml Injection as it may cause unpleasant side effects. Human Mixtard 50 40IU/ml Injection should be given to children only if prescribed by the doctor. Keep your doctor informed about your health condition and medications to rule out any interactions. Human Mixtard 50 40IU/ml Injection is a cold chain medicine, it has to be stored in the refrigerator between 2-8°C else its efficiency may be lost. Do not store in the freezer.

Uses of Human Mixtard 50 40IU/ml Injection

Treatment of Diabetes (Type 1 diabetes mellitus, Type 2 diabetes mellitus)

Medicinal Benefits

Human Mixtard 50 40IU/ml Injection is a combination of two drugs: Human insulin (a short-acting type of insulin) and Insulin isophane (intermediate-acting). Human Mixtard 50 40IU/ml Injection is used for the treatment of both type 1 and type 2 diabetes mellitus. Human Mixtard 50 40IU/ml Injection suppresses the production of sugar in the liver and facilitates the reuptake of sugar in the fat and muscle cells; thereby, Human Mixtard 50 40IU/ml Injection ensures rapid and consistent sugar control.  Human Mixtard 50 40IU/ml Injection helps in improving glycaemic control, which in turn decreases the risk of progression of diabetes complications like damage to the retina (retinopathy), damage to the kidney (nephropathy), damage of nerve cells (neuropathy), delayed wound healing, diabetic foot ulcer.

Directions for Use

Human Mixtard 50 40IU/ml Injection should be administered subcutaneously (in the upper thigh, abdomen, upper arm, or buttocks). It should never be administered intravenously or in the vein. If you are not well trained to self-administer Human Mixtard 50 40IU/ml Injection, ask your healthcare professional to administer it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Human Mixtard 50 40IU/ml Injection

  • Allergic reaction at the site of injection

  • Hypoglycemia (low blood glucose level)

  • Itching

  • Lipodystrophy (skin thickening or pits at the injection site)

  • Oedema (swelling)

  • Rashes

  • Weight gain

Drug Warnings

Do not take Human Mixtard 50 40IU/ml Injection if you are allergic to any of the contents. Inform your doctor if you have hypoglycemia (low blood glucose levels), hypokalemia (low levels of potassium in the blood), heart, kidney or liver problems. Consult a doctor before taking Human Mixtard 50 40IU/ml Injection if you are pregnant or breastfeeding. Human Mixtard 50 40IU/ml Injection may cause dizziness, so drive only if you are alert. You are recommended not to consume alcohol as it may cause unpleasant side effects. Care should be taken when you are travelling across more than 2 time zones; your doctor may adjust your insulin schedule. 

Drug Interactions

Drug-Drug Interaction: Human Mixtard 50 40IU/ml Injection may interact with medicines such as pain killer (aspirin), antibiotic (ciprofloxacin), bronchodilators (albuterol, ipratropium), diuretic (furosemide), anti-hypertensive (metoprolol), anti-depressant (sertraline), oral hypoglycemic agents, monoamine oxidase inhibitors, anabolic steroids, glucocorticoids, thyroid hormones and sympathomimetics.

Drug-Food Interaction: Avoid consumption of alcohol along with Human Mixtard 50 40IU/ml Injection as it may lead to unpleasant side effects.

Drug-Disease Interaction: Inform your doctor if you have kidney disease, liver disease, low potassium level (hypokalaemia), and low blood sugar/glucose level (hypoglycemia).

Drug-Drug Interactions Checker List

  • ASPIRIN
  • CIPROFLOXACIN
  • ALBUTEROL
  • IPRATROPIUM
  • FUROSEMIDE
  • METOPROLOL
  • SERTRALINE

Habit Forming

No

Diet & Lifestyle Advise

  • Include foods rich in healthy carbohydrates and fiber, fruits, whole grains, and vegetables in your diet.
  • Try eating food at regular intervals. Do not skip meals. Also, try not to overeat.
  • Follow a healthy diet and walk for at least a few minutes to complement treatment with Human Mixtard 50 40IU/ml Injection.
  • Maintain a healthy weight by exercising regularly.
  • Rest properly, and avoid stress by doing meditation or yoga.

Special Advise

  • If you feel any symptoms of hypoglycemia (fatigue, dizziness, confusion, heart palpitations, shakiness and anxiety), consult your doctor immediately.  

Disease/Condition Glossary

Diabetes: Diabetes is a chronic or lifelong disease that prevents the body from utilizing insulin properly. Insulin is the hormone that controls sugar levels in the blood. Diabetes is a condition in which blood glucose levels are above normal. It is of two types: type-1 and type-2 diabetes. Type-1 diabetes is a condition in which the pancreas produces little or no insulin. Type-2 diabetes affects the way body processes the sugar. Symptoms of diabetes include lack of energy, tiredness, frequent urination, excess thirst, dry mouth, blurry vision, constant hunger, weight loss, and itchy skin.

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Alcohol

Unsafe

You are recommended not to consume alcohol along with Human Mixtard 50 40IU/ml Injection to avoid unpleasant side effects. Alcohol may cause increased drowsiness.

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Pregnancy

Safe if prescribed

It is safe to use Human Mixtard 50 40IU/ml Injection during pregnancy if prescribed by the doctor. However, consult your doctor if you have any concerns regarding this.

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Breast Feeding

Safe if prescribed

It is safe to use Human Mixtard 50 40IU/ml Injection by breastfeeding mothers if prescribed by the doctor. However, consult your doctor if you have any concerns regarding this.

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Driving

Caution

Human Mixtard 50 40IU/ml Injection may cause drowsiness and hypoglycemia (low blood sugar). Therefore, drive only if you are alert.

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Liver

Caution

Human Mixtard 50 40IU/ml Injection should be taken with caution, especially if you have a history of liver disease. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Human Mixtard 50 40IU/ml Injection should be taken with caution, especially if you have a history of kidney disease. The dose may have to be adjusted by your doctor.

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Children

Safe if prescribed

Human Mixtard 50 40IU/ml Injection can be given safely to children provided the dose has been prescribed by a child specialist.

Country of origin

India

Manufacturer/Marketer address

Plot No.32, 47-50, EPIP Area, Whitefield, Bangalore - 560 066
Other Info - HUM0056

Author Details

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FAQs

Human Mixtard 50 40IU/ml Injection is used for the treatment of both type 1 and type 2 diabetes mellitus.
Human Mixtard 50 40IU/ml Injection suppresses the production of sugar in the liver and facilitates the reuptake of sugar in the fat and muscle cells, thereby Human Mixtard 50 40IU/ml Injection ensures rapid and consistent sugar control.Â
Human Mixtard 50 40IU/ml Injection may sometimes lower the blood glucose levels more than normal, leading to hypoglycaemia. Regularly monitor your blood sugar levels while taking Human Mixtard 50 40IU/ml Injection. Hypoglycaemia symptoms include headache, drowsiness, cold sweat, feeling sick, unusual tiredness or weakness, and visual disturbances.
Do not stop taking Human Mixtard 50 40IU/ml Injection without consulting your doctor on your own as it may cause an increase in blood glucose levels. Continue taking Human Mixtard 50 40IU/ml Injection for as long as your doctor has prescribed it to you. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Human Mixtard 50 40IU/ml Injection.
Maintain a healthy diet by regular intake of carbohydrates such as bread and products containing starch and sugar. Eat your meals regularly, and do not exercise heavily for longer durations with an empty stomach.
Hypoglycaemia may occur following prolonged or severe exercise, during illness, alcohol consumption, low food intake, or when Human Mixtard 50 40IU/ml Injection is taken along with other antidiabetic medicines.
Side effects of Human Mixtard 50 40IU/ml Injection include allergic reaction at the site of injection, hypoglycemia (low blood glucose level), itching, lipodystrophy (skin thickening or pits at the injection site), oedema (swelling), rashes, and weight gain. Most of these side effects may not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.
Cut back on foods high in sodium, alcohol, fried foods, and high-carb food and drinks like sugary drinks, drinks with added sugar, white rice and starchy vegetables.
The injection site should be changed to prevent skin changes like lumps under the skin. Human Mixtard 50 40IU/ml Injection may not work well if injected into the lumpy area.
Maintain a healthy diet and exercise regularly. Limit sugar intake and avoid smoking & alcohol consumption. Manage stress by doing meditation or yoga.
Hypoglycaemia (low blood sugar) may occur because you inject too much insulin, miss or delay meals, do not eat enough, eat food containing less carbohydrate than normal, drink alcohol, lose carbohydrates due to vomiting or diarrhoea, do more exercise than usual or a different type of physical activity, are recovering from an injury, illness, operation or stress, or are taking/have stopped taking other medicines.
Symptoms of high blood sugar include feeling thirsty, increased urination, weakness or tiredness, blurred vision and weight loss.
Human Mixtard 50 40IU/ml Injection is to be injected below the skin (subcutaneously). The best areas to inject Human Mixtard 50 40IU/ml Injection are on your stomach, upper arm, upper thigh, or buttocks.
Unopened vials are to be refrigerated between 2°C and 8°C. Opened vials (in-use) may be stored not above 25ºC for a maximum of 4 weeks. The used needle should be placed in a puncture-resistant disposable container and disposed of properly as directed by your healthcare provider.
Avoid drinking alcohol while taking Human Mixtard 50 40IU/ml Injection as it might lower blood sugar levels and cause hypoglycaemia.

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