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Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
LZ-D 15/5 Tablet is used to treat gastroesophageal reflux disease (GERD), peptic ulcers, and Zollinger-Ellison syndrome. It contains Domperidone and Lansoprazole which work by reducing the amount of acid produced by the stomach and preventing excess acid from flowing back into the food pipe. This medicine may sometimes cause side effects such as diarrhoea, nausea, vomiting, headache, dizziness, stomach pain, or constipation. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Manufacturer/Marketer :

Metis Pharmaceuticals

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About LZ-D 15/5 Tablet

LZ-D 15/5 Tablet belongs to a class of drugs called 'antacids' used to treat gastroesophageal reflux disease (GERD), peptic ulcers, and Zollinger-Ellison syndrome. Gastroesophageal reflux disease (GERD) occurs when stomach acid frequently flows back into the food pipe (oesophagus). Peptic ulcers are sores that develop on the inner lining of the intestine and stomach. Zollinger-Ellison syndrome is characterized by the formation of tumours in the upper part of the small intestine, which leads to excess acid production.

LZ-D 15/5 Tablet is a combination of two medicines, namely: 'Domperidone' and 'Lansoprazole'. Domperidone increases food movement in the stomach, which helps avoid the problems related to indigestion, bloating, and fullness. This medicine also restricts the action of a chemical that is responsible for the feeling of vomiting and nausea. On the other side, Lansoprazole works by blocking the action of proton pumps that are involved in producing stomach acid. Thereby, LZ-D 15/5 Tablet reduces the amount of acid produced by the stomach and prevents excess acid from flowing back into the food pipe. Thus, both medicines in combination provide relief from heartburn symptoms related to acid reflux.

Take LZ-D 15/5 Tablet as prescribed by your doctor. You are advised to take LZ-D 15/5 Tablet for as long as your doctor has prescribed it for you based on your medical condition. You may experience diarrhoea, nausea, vomiting, headache, dizziness, stomach pain, or constipation in some cases. Most of these side effects of LZ-D 15/5 Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to LZ-D 15/5 Tablet or any other medicines, please tell your doctor. LZ-D 15/5 Tablet is not recommended for children as the safety and effectiveness were not established. If you are pregnant or breastfeeding, please inform your doctor before taking LZ-D 15/5 Tablet . Drive only if you are alert as LZ-D 15/5 Tablet may cause drowsiness. Avoid alcohol consumption as it may lead to increased stomach acid production, thereby increasing acidity and heartburn. LZ-D 15/5 Tablet is safe to be used by elderly persons, and no dosage adjustments are required.

Uses of LZ-D 15/5 Tablet

Treatment of Gastroesophageal reflux disease (GERD), Peptic ulcers and Zollinger-Ellison syndrome.

Directions for Use

Take LZ-D 15/5 Tablet on an empty stomach or as advised by your doctor and swallow its as a whole with a glass of water. It is suggested to take LZ-D 15/5 Tablet before meals, probably in the early morning before you take breakfast. Do not crush, chew or break it.

Medicinal Benefits

LZ-D 15/5 Tablet is suggested for the treatment of certain stomach related problems like ulcers and acid reflux. This medicine provides relief in heartburn and reduces the risk associated with acid's damage to the stomach and food pipe. It also reduces the risk of cancer of food pipe, a taste of acid in the mouth, chest pain, and teeth damage. Domperidone helps to increase the movement of the bowel in the intestine. It also treats vomiting and nausea caused by the usage of other medications. While Lansoprazole helps reduce frequent heartburn that happens for 2 or more days.

How LZ-D 15/5 Tablet Works

LZ-D 15/5 Tablet is a combination of two medicines, namely: 'Domperidone' and 'Lansoprazole'. Domperidone increases food movement in the stomach, which helps avoid the problems related to indigestion, bloating, and fullness. This medicine also restricts the action of a chemical that is responsible for the feeling of vomiting and nausea. On the other side, Lansoprazole works by blocking the action of proton pumps that are involved in producing stomach acid. Thereby, LZ-D 15/5 Tablet reduces the amount of acid produced by the stomach and prevents excess acid from flowing back into the food pipe. Thus, both medicines in combination provide relief from heartburn symptoms related to acid reflux.

Storage

Store in a cool and dry place away from sunlight

Side Effects of LZ-D 15/5 Tablet

  • Diarrhoea
  • Nausea
  • Vomiting
  • Headache
  • Dizziness
  • Stomach pain
  • Constipation

What if I have taken an overdose of LZ-D 15/5 Tablet

Avoid exceeding the recommended dose as it might cause an overdose. Seek immediate medical attention if you experience any unusual symptoms.

Drug Warnings

Inform your doctor if you have any risk factors for reduced vitamin B12 as LZ-D 15/5 Tablet may reduce the absorption of vitamin B12. If you get any skin rash, particularly in areas exposed to the sun or pain in joints, inform your doctor. If you get any skin rash, particularly in areas exposed to the sun or pain in joints, inform your doctor. If you are taking LZ-D 15/5 Tablet for more than one year, it may increase the risk of fracture of the spine, hip, or wrist. Drive only if you are alert as LZ-D 15/5 Tablet may cause drowsiness. LZ-D 15/5 Tablet may decrease magnesium levels in the blood, especially if taken for more than three months. Therefore, regular blood tests are recommended to monitor magnesium levels. If you experience bloody or watery diarrhoea with symptoms such as stomach pain, fever, or tenderness, contact your doctor immediately.

Drug-Drug Interactions

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LansoprazoleRilpivirine
Critical
DomperidoneNefazodone
Severe

Drug-Drug Interactions

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LansoprazoleRilpivirine
Critical
How does the drug interact with LZ-D 15/5 Tablet 10's:
Co-administration of LZ-D 15/5 Tablet 10's can make Rilpivirine less effective by reducing its absorption in the body.

How to manage the interaction:
Taking Rilpivirine with LZ-D 15/5 Tablet 10's can result in an interaction, but can be taken if prescribed by the doctor. Do not discontinue any medication without consulting a doctor.
DomperidoneNefazodone
Severe
How does the drug interact with LZ-D 15/5 Tablet 10's:
Coadministration of LZ-D 15/5 Tablet 10's with Nefazodone can increase the blood levels of LZ-D 15/5 Tablet 10's.

How to manage the interaction:
There may be a possibility of interaction between LZ-D 15/5 Tablet 10's and Nefazodone, but it can be taken if prescribed by a doctor. In case you experience any side effects like swelling of the ankles or feet, unusual tiredness, redness, changes in menstrual ability, contact a doctor. It is recommended to do this to ensure your heart stays healthy. Do not stop using any medications without talking to a doctor.
DomperidoneToremifene
Severe
How does the drug interact with LZ-D 15/5 Tablet 10's:
Coadministration of LZ-D 15/5 Tablet 10's with Toremifene can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking LZ-D 15/5 Tablet 10's and Toremifene together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
DomperidoneCitalopram
Severe
How does the drug interact with LZ-D 15/5 Tablet 10's:
Coadministration of LZ-D 15/5 Tablet 10's with Citalopram can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking LZ-D 15/5 Tablet 10's and Citalopram together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
DomperidoneKetoconazole
Severe
How does the drug interact with LZ-D 15/5 Tablet 10's:
Coadministration of LZ-D 15/5 Tablet 10's with Ketoconazole can Increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking LZ-D 15/5 Tablet 10's and Ketoconazole together can cause an interaction, it can be taken if a doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
DomperidoneRitonavir
Severe
How does the drug interact with LZ-D 15/5 Tablet 10's:
Coadministration of LZ-D 15/5 Tablet 10's with Ritonavir can increase the blood levels of LZ-D 15/5 Tablet 10's.

How to manage the interaction:
There may be a possibility of interaction between LZ-D 15/5 Tablet 10's and Ritonavir, but it can be taken if prescribed by a doctor. In case you experience any side effects like swelling of the ankles or feet, unusual tiredness, redness, changes in menstrual ability, contact a doctor. It is recommended to do this to ensure your heart stays healthy. Do not stop using any medications without talking to a doctor.
DomperidoneBepridil
Severe
How does the drug interact with LZ-D 15/5 Tablet 10's:
Co-administration of Domeperidone and Bepridil can increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking LZ-D 15/5 Tablet 10's and Bepridil together can cause an interaction, it can be taken if your doctor has suggested it. If you experience lightheadedness, tiredness, increased heart rate, consult a doctor. Do not discontinue any medications without consulting a doctor.
DomperidoneCisapride
Severe
How does the drug interact with LZ-D 15/5 Tablet 10's:
Coadministration of LZ-D 15/5 Tablet 10's with Cisapride can increase the blood levels of LZ-D 15/5 Tablet 10's.

How to manage the interaction:
There may be a possibility of interaction between LZ-D 15/5 Tablet 10's and Cisapride, but it can be taken if prescribed by a doctor. In case you experience any side effects like swelling of the ankles or feet, unusual tiredness, redness, changes in menstrual ability, contact a doctor. It is recommended to do this to ensure your heart stays healthy. Do not stop using any medications without talking to a doctor.
DomperidoneClarithromycin
Severe
How does the drug interact with LZ-D 15/5 Tablet 10's:
Coadministration of LZ-D 15/5 Tablet 10's with Clarithromycin can increase the risk of side effects.

How to manage the interaction:
There may be a possibility of interaction between LZ-D 15/5 Tablet 10's and Clarithromycin, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
DomperidoneMizolastine
Severe
How does the drug interact with LZ-D 15/5 Tablet 10's:
Combining Mizolastine with LZ-D 15/5 Tablet 10's can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Although taking LZ-D 15/5 Tablet 10's and Mizolastine together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat smaller meals more often.
  • Maintain a healthy weight by regular exercising.
  • Avoid lying down after eating as it causes acid reflux.
  • Avoid tight-fitting clothes as it might increase the pressure on the abdomen leading to acid reflux.
  • Practice relaxation techniques and avoid stress by doing yoga or meditation.
  • Avoid foods such as high-fat food, spicy food, chocolates, citrus fruits, pineapple, tomato, onion, garlic, tea, and soda.
  • Avoid sitting continuously as it may trigger acidity. Take a break of 5 minutes every hour by doing brisk walking or stretching.
  • Avoid smoking and alcohol consumption. Alcohol intake leads to increased production of stomach acid, thereby increases acidity and heartburn.

Habit Forming

No

Therapeutic Class

ANTACIDS

LZ-D 15/5 Tablet Substitute

Substitutes safety advice
  • Lanzeon-D Kid Tablet 10's

    8.64per tablet
  • Lanzonour-D Kid Tablet MD

    7.47per tablet
  • Relife Kids Tablet MD Orange

    8.03per tablet
  • Lansohub Kid Mouth Dissolving Tablet 10's

    7.20per tablet
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Alcohol

Unsafe

Avoid alcohol consumption as it may lead to increased production of stomach acid, thereby irritates the stomach lining and worsen the symptoms.

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Pregnancy

Caution

LZ-D 15/5 Tablet is a category B pregnancy drug and is given to pregnant women only if the doctor thinks benefits outweigh risks. Please consult a doctor if you are pregnant.

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Breast Feeding

Unsafe

LZ-D 15/5 Tablet is usually contraindicated in breastfeeding mothers. Therefore, please consult a doctor before taking LZ-D 15/5 Tablet if you are breastfeeding.

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Driving

Caution

LZ-D 15/5 Tablet may cause drowsiness in some people. Therefore, avoid driving or operating machinery if you feel drowsy after taking LZ-D 15/5 Tablet .

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Liver

Caution

Take LZ-D 15/5 Tablet with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take LZ-D 15/5 Tablet with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Unsafe

LZ-D 15/5 Tablet is not recommended for children as the safety and effectiveness were not established.

FAQs

LZ-D 15/5 Tablet is used to treat gastroesophageal reflux disease (GERD), peptic ulcers, and Zollinger-Ellison syndrome.
LZ-D 15/5 Tablet is a combination of two medicines namely: "Domperidone" and "Lansoprazole". Domperidone increases the movement of food in the stomach which helps to avoid the problems related to indigestion, bloating, and fullness. This medicine also restricts the action of a chemical that is responsible for the feeling of vomiting and nausea. On the other side, Lansoprazole works by blocking the action of proton pumps that are involved in producing stomach acid. Thereby, LZ-D 15/5 Tablet reduces the amount of acid produced by the stomach and prevents excess acid from flowing back into the food pipe. Thus, both medicines in combination provide relief from heartburn symptoms related to acid reflux.
LZ-D 15/5 Tablet may cause diarrhoea as a common side effect. However, if the condition persists or worsens with fever, watery or bloody stools or consistent stomach pain, please consult a doctor. Also, drink plenty of water while taking LZ-D 15/5 Tablet to prevent dehydration.
LZ-D 15/5 Tablet may cause low levels of magnesium in the blood if taken for more than 3 months. If you experience involuntary muscle contractions, tiredness fits, increased heart rate or dizziness while taking LZ-D 15/5 Tablet , please consult a doctor immediately as these might be signs of low magnesium levels. However, regular blood tests are recommended to monitor magnesium levels in the blood while taking LZ-D 15/5 Tablet .
You are not recommended to take LZ-D 15/5 Tablet with antifungals such as ketoconazole or itraconazole as it may reduce the effectiveness of antifungal against fungal infections. However, please consult your doctor before taking LZ-D 15/5 Tablet with other medicines.
LZ-D 15/5 Tablet should be used with caution in osteoporosis (weak and brittle bones) patients as it may worsen the condition especially if LZ-D 15/5 Tablet is taken for more than 1 year as it increases the risk of fracture of the spine, hip or wrist. Therefore, inform your doctor if you have osteoporosis or take any steroids which may increase the risk of osteoporosis.
It is best to take whole grains food like brown rice, green vegetables, sweet potatoes, and carrots to reduce acidity.
Taking LZ-D 15/5 Tablet for longer than the duration recommended by your doctor may increase the risk of side effects. Prolonged use of LZ-D 15/5 Tablet may lead to heart-related issues due to domperidone. If taken for over a year, it may also result in hypomagnesemia (low magnesium levels), vitamin B12 deficiencies, bone fractures, and gut infections due to lansoprazole. Therefore, it is important to regularly monitor your health to determine whether you should continue taking LZ-D 15/5 Tablet . Always follow your doctor's advice and discuss any concerns about long-term use with them.
Yes, smoking and alcohol can increase acidity and contribute to GERD (Gastroesophageal Reflux Disease). Smoking is a major cause of GERD, while alcohol primarily triggers acid reflux episodes. Both smoking and alcohol can weaken the lower oesophageal sphincter, the muscle that keeps acid in the stomach, allowing it to flow back into the oesophagus. Smoking also reduces the amount of saliva that helps neutralize acid in the oesophagus, while alcohol can irritate the lining of both the stomach and the oesophagus. It is advisable to limit or avoid smoking and alcohol to help manage acidity and GERD.
The common side effects of LZ-D 15/5 Tablet include diarrhoea, nausea, vomiting, headache, dizziness, stomach pain, and constipation in some cases. Most of these side effects of LZ-D 15/5 Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Country of origin

India

Manufacturer/Marketer address

Shop No. 17, Flat No. 9 Ews Colony, Purena Raipur Raipur Ct 492001 In
Other Info - LZD0002

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