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Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Last Updated Nov 30, 2024 | 3:21 PM IST
LZ-D 15/5 Tablet is used to treat gastroesophageal reflux disease (GERD), peptic ulcers, and Zollinger-Ellison syndrome. It contains Domperidone and Lansoprazole which work by reducing the amount of acid produced by the stomach and preventing excess acid from flowing back into the food pipe. This medicine may sometimes cause side effects such as diarrhoea, nausea, vomiting, headache, dizziness, stomach pain, or constipation. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Prescription drug

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Prescription drug
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Manufacturer/Marketer

Metis Pharmaceuticals

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About LZ-D 15/5 Tablet

LZ-D 15/5 Tablet belongs to a class of drugs called 'antacids' used to treat gastroesophageal reflux disease (GERD), peptic ulcers, and Zollinger-Ellison syndrome. Gastroesophageal reflux disease (GERD) occurs when stomach acid frequently flows back into the food pipe (oesophagus). Peptic ulcers are sores that develop on the inner lining of the intestine and stomach. Zollinger-Ellison syndrome is characterized by the formation of tumours in the upper part of the small intestine, which leads to excess acid production.

LZ-D 15/5 Tablet is a combination of two medicines, namely: 'Domperidone' and 'Lansoprazole'. Domperidone increases food movement in the stomach, which helps avoid the problems related to indigestion, bloating, and fullness. This medicine also restricts the action of a chemical that is responsible for the feeling of vomiting and nausea. On the other side, Lansoprazole works by blocking the action of proton pumps that are involved in producing stomach acid. Thereby, LZ-D 15/5 Tablet reduces the amount of acid produced by the stomach and prevents excess acid from flowing back into the food pipe. Thus, both medicines in combination provide relief from heartburn symptoms related to acid reflux.

Take LZ-D 15/5 Tablet as prescribed by your doctor. You are advised to take LZ-D 15/5 Tablet for as long as your doctor has prescribed it for you based on your medical condition. You may experience diarrhoea, nausea, vomiting, headache, dizziness, stomach pain, or constipation in some cases. Most of these side effects of LZ-D 15/5 Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to LZ-D 15/5 Tablet or any other medicines, please tell your doctor. LZ-D 15/5 Tablet is not recommended for children as the safety and effectiveness were not established. If you are pregnant or breastfeeding, please inform your doctor before taking LZ-D 15/5 Tablet . Drive only if you are alert as LZ-D 15/5 Tablet may cause drowsiness. Avoid alcohol consumption as it may lead to increased stomach acid production, thereby increasing acidity and heartburn. LZ-D 15/5 Tablet is safe to be used by elderly persons, and no dosage adjustments are required.

Uses of LZ-D 15/5 Tablet

Treatment of Gastroesophageal reflux disease (GERD), Peptic ulcers and Zollinger-Ellison syndrome.

Medicinal Benefits

LZ-D 15/5 Tablet is suggested for the treatment of certain stomach related problems like ulcers and acid reflux. This medicine provides relief in heartburn and reduces the risk associated with acid's damage to the stomach and food pipe. It also reduces the risk of cancer of food pipe, a taste of acid in the mouth, chest pain, and teeth damage. Domperidone helps to increase the movement of the bowel in the intestine. It also treats vomiting and nausea caused by the usage of other medications. While Lansoprazole helps reduce frequent heartburn that happens for 2 or more days.

Directions for Use

Take LZ-D 15/5 Tablet on an empty stomach or as advised by your doctor and swallow its as a whole with a glass of water. It is suggested to take LZ-D 15/5 Tablet before meals, probably in the early morning before you take breakfast. Do not crush, chew or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of LZ-D 15/5 Tablet

  • Diarrhoea
  • Nausea
  • Vomiting
  • Headache
  • Dizziness
  • Stomach pain
  • Constipation

Drug Warnings

Inform your doctor if you have any risk factors for reduced vitamin B12 as LZ-D 15/5 Tablet may reduce the absorption of vitamin B12. If you get any skin rash, particularly in areas exposed to the sun or pain in joints, inform your doctor. If you get any skin rash, particularly in areas exposed to the sun or pain in joints, inform your doctor. If you are taking LZ-D 15/5 Tablet for more than one year, it may increase the risk of fracture of the spine, hip, or wrist. Drive only if you are alert as LZ-D 15/5 Tablet may cause drowsiness. LZ-D 15/5 Tablet may decrease magnesium levels in the blood, especially if taken for more than three months. Therefore, regular blood tests are recommended to monitor magnesium levels. If you experience bloody or watery diarrhoea with symptoms such as stomach pain, fever, or tenderness, contact your doctor immediately.

Drug Interactions

Drug-Drug Interactions: LZ-D 15/5 Tablet may interact with the anti-HIV drug (atazanavir), antifungals (ketoconazole, itraconazole), anticancer drug (methotrexate), heart-related medicine (digoxin), and blood thinner (warfarin).

Drug-Food Interactions: LZ-D 15/5 Tablet may interact with St. John’s wort (herbal supplement used to treat depression). Avoid alcohol consumption as alcohol intake leads to increased stomach acid production, thereby irritating the stomach lining and worsening the symptoms.

Drug-Disease Interactions: If you have a stomach tumor, liver problems, low magnesium levels in the blood, osteoporosis (weak and brittle bones), or lupus (an autoimmune disorder), inform your doctor before taking LZ-D 15/5 Tablet .

Drug-Drug Interactions Checker List

  • ITRACONAZOLE
  • METHOTREXATE
  • WARFARIN
  • KETOCONAZOLE
  • DIGOXIN
  • ATAZANAVIR

Habit Forming

No

Diet & Lifestyle Advise

  • Eat smaller meals more often.
  • Maintain a healthy weight by regular exercising.
  • Avoid lying down after eating as it causes acid reflux.
  • Avoid tight-fitting clothes as it might increase the pressure on the abdomen leading to acid reflux.
  • Practice relaxation techniques and avoid stress by doing yoga or meditation.
  • Avoid foods such as high-fat food, spicy food, chocolates, citrus fruits, pineapple, tomato, onion, garlic, tea, and soda.
  • Avoid sitting continuously as it may trigger acidity. Take a break of 5 minutes every hour by doing brisk walking or stretching.
  • Avoid smoking and alcohol consumption. Alcohol intake leads to increased production of stomach acid, thereby increases acidity and heartburn.

Special Advise

  • Regular blood tests are recommended while taking LZ-D 15/5 Tablet to monitor magnesium levels in the blood.
  • LZ-D 15/5 Tablet may cause some abnormal liver enzyme and blood values. These changes are temporary and may return to normal after treatment with LZ-D 15/5 Tablet is discontinued.

Disease/Condition Glossary

Gastroesophageal reflux disease (GERD): The stomach is usually protected from the acid by a mucous layer. In some cases, due to excess acid production, the mucous layer gets irritated or eroded, which leads to complications like GERD, hyperacidity, peptic ulcers, and heartburn. Gastroesophageal reflux disease (GERD) occurs when stomach acid frequently flows back into the food pipe (oesophagus). This backflow (acid reflux) irritates the food pipe and causes heartburn. Symptoms include heartburn, sour or bitter taste in the mouth, and difficulty swallowing.

Peptic ulcers: These are sores that develop on the stomach and intestine lining due to erosion of the stomach protective lining. Symptoms include nausea, appetite changes, bloody or dark stools, unexplained weight loss, vomiting, and indigestion.

Zollinger-Ellison syndrome: It is characterized by the formation of tumours in the upper part of the small intestine, which leads to excess acid production. Symptoms include bloating, burping, weight loss, loss of appetite, nausea, and vomiting.

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Alcohol

Unsafe

Avoid alcohol consumption as it may lead to increased production of stomach acid, thereby irritates the stomach lining and worsen the symptoms.

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Pregnancy

Caution

LZ-D 15/5 Tablet is a category B pregnancy drug and is given to pregnant women only if the doctor thinks benefits outweigh risks. Please consult a doctor if you are pregnant.

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Breast Feeding

Unsafe

LZ-D 15/5 Tablet is usually contraindicated in breastfeeding mothers. Therefore, please consult a doctor before taking LZ-D 15/5 Tablet if you are breastfeeding.

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Driving

Caution

LZ-D 15/5 Tablet may cause drowsiness in some people. Therefore, avoid driving or operating machinery if you feel drowsy after taking LZ-D 15/5 Tablet .

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Liver

Caution

Take LZ-D 15/5 Tablet with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take LZ-D 15/5 Tablet with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Unsafe

LZ-D 15/5 Tablet is not recommended for children as the safety and effectiveness were not established.

Country of origin

India

Manufacturer/Marketer address

Shop No. 17, Flat No. 9 Ews Colony, Purena Raipur Raipur Ct 492001 In
Other Info - LZD0002

FAQs

LZ-D 15/5 Tablet is used to treat gastroesophageal reflux disease (GERD), peptic ulcers, and Zollinger-Ellison syndrome.
LZ-D 15/5 Tablet is a combination of two medicines namely: "Domperidone" and "Lansoprazole". Domperidone increases the movement of food in the stomach which helps to avoid the problems related to indigestion, bloating, and fullness. This medicine also restricts the action of a chemical that is responsible for the feeling of vomiting and nausea. On the other side, Lansoprazole works by blocking the action of proton pumps that are involved in producing stomach acid. Thereby, LZ-D 15/5 Tablet reduces the amount of acid produced by the stomach and prevents excess acid from flowing back into the food pipe. Thus, both medicines in combination provide relief from heartburn symptoms related to acid reflux.
LZ-D 15/5 Tablet may cause diarrhoea as a common side effect. However, if the condition persists or worsens with fever, watery or bloody stools or consistent stomach pain, please consult a doctor. Also, drink plenty of water while taking LZ-D 15/5 Tablet to prevent dehydration.
LZ-D 15/5 Tablet may cause low levels of magnesium in the blood if taken for more than 3 months. If you experience involuntary muscle contractions, tiredness fits, increased heart rate or dizziness while taking LZ-D 15/5 Tablet , please consult a doctor immediately as these might be signs of low magnesium levels. However, regular blood tests are recommended to monitor magnesium levels in the blood while taking LZ-D 15/5 Tablet .
You are not recommended to take LZ-D 15/5 Tablet with antifungals such as ketoconazole or itraconazole as it may reduce the effectiveness of antifungal against fungal infections. However, please consult your doctor before taking LZ-D 15/5 Tablet with other medicines.
LZ-D 15/5 Tablet should be used with caution in osteoporosis (weak and brittle bones) patients as it may worsen the condition especially if LZ-D 15/5 Tablet is taken for more than 1 year as it increases the risk of fracture of the spine, hip or wrist. Therefore, inform your doctor if you have osteoporosis or take any steroids which may increase the risk of osteoporosis.
It is best to take whole grains food like brown rice, green vegetables, sweet potatoes, and carrots to reduce acidity.
Taking LZ-D 15/5 Tablet for longer than the duration recommended by your doctor may increase the risk of side effects. Prolonged use of LZ-D 15/5 Tablet may lead to heart-related issues due to domperidone. If taken for over a year, it may also result in hypomagnesemia (low magnesium levels), vitamin B12 deficiencies, bone fractures, and gut infections due to lansoprazole. Therefore, it is important to regularly monitor your health to determine whether you should continue taking LZ-D 15/5 Tablet . Always follow your doctor's advice and discuss any concerns about long-term use with them.
Yes, smoking and alcohol can increase acidity and contribute to GERD (Gastroesophageal Reflux Disease). Smoking is a major cause of GERD, while alcohol primarily triggers acid reflux episodes. Both smoking and alcohol can weaken the lower oesophageal sphincter, the muscle that keeps acid in the stomach, allowing it to flow back into the oesophagus. Smoking also reduces the amount of saliva that helps neutralize acid in the oesophagus, while alcohol can irritate the lining of both the stomach and the oesophagus. It is advisable to limit or avoid smoking and alcohol to help manage acidity and GERD.
The common side effects of LZ-D 15/5 Tablet include diarrhoea, nausea, vomiting, headache, dizziness, stomach pain, and constipation in some cases. Most of these side effects of LZ-D 15/5 Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

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