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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Lariago Tablet is used to treat malaria. It gives a degree of protection against malaria when people travel to areas where malaria cases exist. It is effective against Plasmodium vivax, Plasmodium ovale, and Plasmodium malariae. It is not effective against Plasmodium falciparum. Besides this, it also treats amoebiasis (intestinal dysentery) and rheumatic disease (arthritis). It contains Chloroquine, which kills the organisms causing malaria and amoebiasis. It may cause common side effects such as vomiting, nausea, hair loss and itchy skin. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Composition :

CHLOROQUINE-250MG

Manufacturer/Marketer :

Ipca Laboratories Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Lariago Tablet

Lariago Tablet belongs to the class of medications called 'quinoline' primarily used to treat malaria. Lariago Tablet gives a degree of protection (prophylaxis) against malaria when people travel to areas where malarial cases exist. It is effective against Plasmodium vivax, Plasmodium ovale, and Plasmodium malariae. Lariago Tablet is not effective against Plasmodium falciparum. Besides this, it also treats amoebiasis (intestinal dysentery) and rheumatic disease (arthritis). 

Lariago Tablet contains 'chloroquine' which acts by killing the malarial parasites, i.e. Plasmodium and stops the formation of the nontoxic heme metabolite hemozoin by the parasite. Heme part of the red blood cells is broken by the malarial, causing parasites. Lariago Tablet  prevents the breakdown of heme part and is actually toxic to the parasite. It kills the parasitic form living in red blood cells that resides in the liver.

Lariago Tablet should be taken as prescribed by your doctor. The dose of Lariago Tablet can vary depending upon your condition and the severity of the infection. The common side effects of Lariago Tablet include vomiting, nausea, hair loss and itchy skin. Everyone need not experience the above side effects. In case of any discomfort, speak with a doctor.

Before starting Lariago Tablet , please inform your doctor if you are allergic to chloroquine or have kidney or liver problems. Do not take Lariago Tablet on your own. Lariago Tablet is safe to use during pregnancy and breastfeeding. Prolonged use of Lariago Tablet may have a severe risk on the heart and retina of the eyes leading to pounding heartbeats and permanent vision problems. 

Uses of Lariago Tablet

Treatment of Malaria, Intestinal amoebiasis, Rheumatoid arthritis.

Directions for Use

Tablet/Capsule: Swallow it as a whole with water; do not crush, break or chew it.Syrup/Suspension: Shake the bottle well before use. Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper provided by the pack.

Medicinal Benefits

Lariago Tablet falls into a group of medicines known as antimalarials, indicated for treating or preventing malaria. Lariago Tablet contains chloroquine, which belongs to quinoline. It works by preventing the formation of the nontoxic heme metabolite hemozoin by the parasite. Due to this, the parasite dies from its own toxic by-products released due to haemoglobin's metabolism. Lariago Tablet is also indicated for the treatment of rheumatoid arthritis and autoimmune diseases like lupus and intestinal infection caused by amoeba (amoebiasis).

How Lariago Tablet Works

Lariago Tablet contains 'chloroquine' which acts by killing the malarial parasites, i.e. Plasmodium and stops the formation of the nontoxic heme metabolite hemozoin by the parasite. Heme part of the red blood cells is broken by the malarial, causing parasites. Lariago Tablet  prevents the breakdown of heme part and is actually toxic to the parasite. It kills the parasitic form living in red blood cells that resides in the liver.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Lariago Tablet

  • Abnormal heart rhythm
  • Stomach pain
  • Nausea (being sick)
  • Diarrhoea
  • Loss of appetite
  • Headache
  • Skin rash
  • Liver problems

What if I have taken an overdose of Lariago Tablet

Do not take more than the prescribed dose of Lariago Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Lariago Tablet does not respond well against all malaria strains, so consult with your doctor if you do not respond well to Lariago Tablet . This medicine can affect heart health, especially if a person is taking medications, including the antibiotic azithromycin and anticancer like tamoxifen. An individual must consult with the doctor if they are noticing fast or pounding heartbeats and sudden dizziness. This medicine cannot be used for a long duration as it may cause irreversible damage to the eye that could lead to vision problems. Lariago Tablet cannot be used in persons who have heart disease, heart rhythm disorder, diabetes, a stomach disorder, an allergy to quinine, liver or kidney disease, psoriasis, alcoholism, porphyria (a genetic enzyme disorder that affects the skin or nervous system), a genetic enzyme deficiency called glucose-6-phosphate dehydrogenase (G6PD) deficiency. Consult with your doctor if you are pregnant or breastfeeding as this medicine could only be used if prescribed by the doctor. 

Drug-Drug Interactions

verifiedApollotooltip
ChloroquineAgalsidase beta
Critical
ChloroquineThioridazine
Critical

Drug-Drug Interactions

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ChloroquineAgalsidase beta
Critical
How does the drug interact with Lariago Tablet 10's:
Using Lariago Tablet 10's with Agalsidase beta can reduce the effectiveness of agalsidase beta.

How to manage the interaction:
Taking Agalsidase beta with Lariago Tablet 10's is not recommended, but can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms contact a doctor immediately. Do not stop using any medications without talking to a doctor.
ChloroquineThioridazine
Critical
How does the drug interact with Lariago Tablet 10's:
When Thioridazine and Lariago Tablet 10's are taken together, can increase the chance of a serious abnormal heart rhythm

How to manage the interaction:
Taking Lariago Tablet 10's with Thioridazine is not recommended, as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
ChloroquineCisapride
Critical
How does the drug interact with Lariago Tablet 10's:
Taking Lariago Tablet 10's with Cisapride can increase the risk of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Lariago Tablet 10's with Cisapride is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately.
ChloroquineBepridil
Critical
How does the drug interact with Lariago Tablet 10's:
Using Lariago Tablet 10's together with bepridil can increase the risk of an irregular heart rhythm

How to manage the interaction:
Taking Lariago Tablet 10's with Bepridil is not recommended, as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately.
ChloroquineAgalsidase alfa
Critical
How does the drug interact with Lariago Tablet 10's:
When Agalsidase alfa is used with Lariago Tablet 10's, it may decrease the effectiveness of the Agalsidase alfa.

How to manage the interaction:
Taking Agalsidase alfa with Lariago Tablet 10's is not recommended, it can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not stop using any medications without talking to a doctor.
ChloroquineAurothioglucose
Critical
How does the drug interact with Lariago Tablet 10's:
Taking Aurothioglucose with Lariago Tablet 10's can cause blood disorders and other severe side effects

How to manage the interaction:
Taking Aurothioglucose with Lariago Tablet 10's is not recommended, as it can cause an interaction, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience unusual symptoms. Do not discontinue any medications without consulting a doctor.
ChloroquineDronedarone
Critical
How does the drug interact with Lariago Tablet 10's:
When Lariago Tablet 10's is taken with Dronedarone, it may increase the risk of abnormal heart rhythm.

How to manage the interaction:
Taking Lariago Tablet 10's with Dronedarone is not recommended, as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
ChloroquinePimozide
Critical
How does the drug interact with Lariago Tablet 10's:
When Pimozide and Lariago Tablet 10's are taken together, it can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Lariago Tablet 10's with Pimozide is not recommended, as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
ChloroquineSparfloxacin
Critical
How does the drug interact with Lariago Tablet 10's:
Using Lariago Tablet 10's together with sparfloxacin can increase the risk of an irregular heart rhythm

How to manage the interaction:
Taking Lariago Tablet 10's with Sparfloxacin is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience unusual symptoms. Do not discontinue any medications without consulting a doctor.
ChloroquineZiprasidone
Critical
How does the drug interact with Lariago Tablet 10's:
Taking Lariago Tablet 10's with Ziprasidone can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Lariago Tablet 10's with Ziprasidone is not recommended, it can be taken together if prescribed by a doctor. However, consult a doctor if you experience dizziness, drowsiness, confusion, and difficulty concentrating. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Always take Lariago Tablet with meals for reduced gastric irritation.
  • Adequate nutrition is the key for improvement in malaria induced weakness.
  • It is important to allow the patient to eat regularly in small amounts to tolerate the food. 
  • Increase fluid and protein intake for malaria induced weight loss.
  • Proper rest and mosquito-free premises is important for the patient to recover.

Habit Forming

No

Therapeutic Class

ANTI- MALARIALS

Lariago Tablet Substitute

Substitutes safety advice
  • EMQUIN 250MG TABLET

    0.81per tablet
  • RESOCHIN TABLET

    1.08per tablet
  • Resochin Tablet 10's

    1.13per tablet
  • Leoquin EC 250 Tablet 10's

    1.08per tablet
  • Quinross 250mg Tablet

    0.88per tablet
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Alcohol

Caution

No serious interaction has been reported between alcohol and Lariago Tablet yet alcohol should be avoided with Lariago Tablet as it aggravates side effects.

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Pregnancy

Caution

Lariago Tablet should be used with caution and can only be used in pregnancy if recommended by the doctor.

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Breast Feeding

Caution

It is not safe to breastfeed while taking Lariago Tablet as this medicine can pass into breast milk. A patient is advised to take this drug only on doctor's consultation.

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Driving

Caution

Lariago Tablet may cause blurred vision, so one should avoid driving or doing any activity that needs mental alertness. A patient is thus advised to take this drug only on doctor's consultation.

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Liver

Caution

Lariago Tablet therapy is unlikely to cause liver injury in normal individuals but can trigger an acute worsening of porphyria in rare cases. Thus doctor's consultation is recommended before taking Lariago Tablet .

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Kidney

Caution

Lariago Tablet administration impairs kidney function in a few cases, so a patient is recommended to consult a doctor before taking Lariago Tablet .

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Children

Safe if prescribed

Lariago Tablet is safe to use in children, yet dose adjustment by a doctor will be done on the basis of age, weight, and severity of the infection.

FAQs

Lariago Tablet is used to treat malaria. Lariago Tablet gives a degree of protection against malaria when people travel to areas where malarial cases exist. It is effective against Plasmodium vivax, Plasmodium ovale, and Plasmodium malariae. Lariago Tablet is not effective against Plasmodium falciparum. Besides this, it also treats amoebiasis (intestinal dysentery) and rheumatic disease (arthritis).
Lariago Tablet works by preventing the formation of the nontoxic heme metabolite hemozoin by the parasite. Due to this, the parasite dies from its own toxic by-products released due to haemoglobin's metabolism.
The use of Lariago Tablet is not allowed in persons who are already taking any antibiotic (azithromycin) as it may cause dangerous effects on the heart.
No such effect has been reported yet. Always consult your doctor for the change of dose regimen or an alternative medicine if needed.
No such harmful interaction has been reported in patients who take this drug under strict doctors' surveillance. However, some patients might experience eye (retina) damage and cause pounding heart, so patient taking Lariago Tablet is advised to consult a doctor and have regular check-ups cyclically.
There may be a risk of hemolysis in patients with G6PD deficiency while using Lariago Tablet . Doctor's consultation is mandatory before you start this medication.

Country of origin

India

Manufacturer/Marketer address

142 AB, Kandivli Industrial Estate, Kandivli (West), Mumbai - 400 067, Maharashtra
Other Info - LAR0005

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