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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Jan 1, 2025 | 2:49 PM IST
Arquin 250mg Syrup is used to treat malaria. It gives a degree of protection against malaria when people travel to areas where malaria cases exist. It is effective against Plasmodium vivax, Plasmodium ovale, and Plasmodium malariae. It is not effective against Plasmodium falciparum. Besides this, it also treats amoebiasis (intestinal dysentery) and rheumatic disease (arthritis). It contains Chloroquine, which kills the organisms causing malaria and amoebiasis. It may cause common side effects such as vomiting, nausea, hair loss and itchy skin. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Composition :

CHLOROQUINE-250MG

Manufacturer/Marketer :

Agron Remedies Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

About Arquin 250mg Syrup

Arquin 250mg Syrup belongs to the class of medications called 'quinoline' primarily used to treat malaria. Arquin 250mg Syrup gives a degree of protection (prophylaxis) against malaria when people travel to areas where malarial cases exist. It is effective against Plasmodium vivax, Plasmodium ovale, and Plasmodium malariae. Arquin 250mg Syrup is not effective against Plasmodium falciparum. Besides this, it also treats amoebiasis (intestinal dysentery) and rheumatic disease (arthritis). 

Arquin 250mg Syrup contains 'chloroquine' which acts by killing the malarial parasites, i.e. Plasmodium and stops the formation of the nontoxic heme metabolite hemozoin by the parasite. Heme part of the red blood cells is broken by the malarial, causing parasites. Arquin 250mg Syrup prevents the breakdown of heme part and is actually toxic to the parasite. It kills the parasitic form living in red blood cells that resides in the liver.

Arquin 250mg Syrup should be taken as prescribed by your doctor. The dose of Arquin 250mg Syrup can vary depending upon your condition and the severity of the infection. The common side effects of Arquin 250mg Syrup include vomiting, nausea, hair loss and itchy skin. Everyone need not experience the above side effects. In case of any discomfort, speak with a doctor.

Before starting Arquin 250mg Syrup, please inform your doctor if you are allergic to chloroquine or have kidney or liver problems. Do not take Arquin 250mg Syrup on your own. Arquin 250mg Syrup is safe to use during pregnancy and breastfeeding. Prolonged use of Arquin 250mg Syrup may have a severe risk on the heart and retina of the eyes leading to pounding heartbeats and permanent vision problems. 

Uses of Arquin 250mg Syrup

Treatment of Malaria, Intestinal amoebiasis, Rheumatoid arthritis.

Medicinal Benefits

Arquin 250mg Syrup falls into a group of medicines known as antimalarials, indicated for treating or preventing malaria. Arquin 250mg Syrup contains chloroquine, which belongs to quinoline. It works by preventing the formation of the nontoxic heme metabolite hemozoin by the parasite. Due to this, the parasite dies from its own toxic by-products released due to haemoglobin's metabolism. Arquin 250mg Syrup is also indicated for the treatment of rheumatoid arthritis and autoimmune diseases like lupus and intestinal infection caused by amoeba (amoebiasis).

Side Effects of Arquin 250mg Syrup

  • Abnormal heart rhythm
  • Stomach pain
  • Nausea (being sick)
  • Diarrhoea
  • Loss of appetite
  • Headache
  • Skin rash
  • Liver problems

Directions for Use

Tablet/Capsule: Swallow it as a whole with water; do not crush, break or chew it.Syrup/Suspension: Shake the bottle well before use. Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper provided by the pack.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Arquin 250mg Syrup does not respond well against all malaria strains, so consult with your doctor if you do not respond well to Arquin 250mg Syrup. This medicine can affect heart health, especially if a person is taking medications, including the antibiotic azithromycin and anticancer like tamoxifen. An individual must consult with the doctor if they are noticing fast or pounding heartbeats and sudden dizziness. This medicine cannot be used for a long duration as it may cause irreversible damage to the eye that could lead to vision problems. Arquin 250mg Syrup cannot be used in persons who have heart disease, heart rhythm disorder, diabetes, a stomach disorder, an allergy to quinine, liver or kidney disease, psoriasis, alcoholism, porphyria (a genetic enzyme disorder that affects the skin or nervous system), a genetic enzyme deficiency called glucose-6-phosphate dehydrogenase (G6PD) deficiency. Consult with your doctor if you are pregnant or breastfeeding as this medicine could only be used if prescribed by the doctor. 

Therapeutic Class

ANTI- MALARIALS

Diet & Lifestyle Advise

  • Always take Arquin 250mg Syrup with meals for reduced gastric irritation.
  • Adequate nutrition is the key for improvement in malaria induced weakness.
  • It is important to allow the patient to eat regularly in small amounts to tolerate the food. 
  • Increase fluid and protein intake for malaria induced weight loss.
  • Proper rest and mosquito-free premises is important for the patient to recover.

Habit Forming

No

How Arquin 250mg Syrup Works

Arquin 250mg Syrup contains 'chloroquine' which acts by killing the malarial parasites, i.e. Plasmodium and stops the formation of the nontoxic heme metabolite hemozoin by the parasite. Heme part of the red blood cells is broken by the malarial, causing parasites. Arquin 250mg Syrup prevents the breakdown of heme part and is actually toxic to the parasite. It kills the parasitic form living in red blood cells that resides in the liver.

What if I have taken an overdose of Arquin 250mg Syrup

Do not take more than the prescribed dose of Arquin 250mg Syrup as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.
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Alcohol

Caution

No serious interaction has been reported between alcohol and Arquin 250mg Syrup yet alcohol should be avoided with Arquin 250mg Syrup as it aggravates side effects.

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Pregnancy

Caution

Arquin 250mg Syrup should be used with caution and can only be used in pregnancy if recommended by the doctor.

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Breast Feeding

Caution

It is not safe to breastfeed while taking Arquin 250mg Syrup as this medicine can pass into breast milk. A patient is advised to take this drug only on doctor's consultation.

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Driving

Caution

Arquin 250mg Syrup may cause blurred vision, so one should avoid driving or doing any activity that needs mental alertness. A patient is thus advised to take this drug only on doctor's consultation.

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Liver

Caution

Arquin 250mg Syrup therapy is unlikely to cause liver injury in normal individuals but can trigger an acute worsening of porphyria in rare cases. Thus doctor's consultation is recommended before taking Arquin 250mg Syrup.

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Kidney

Caution

Arquin 250mg Syrup administration impairs kidney function in a few cases, so a patient is recommended to consult a doctor before taking Arquin 250mg Syrup.

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Children

Safe if prescribed

Arquin 250mg Syrup is safe to use in children, yet dose adjustment by a doctor will be done on the basis of age, weight, and severity of the infection.

Country of origin

India
Other Info - AR91982

Author Details

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FAQs

Arquin 250mg Syrup is used to treat malaria. Arquin 250mg Syrup gives a degree of protection against malaria when people travel to areas where malarial cases exist. It is effective against Plasmodium vivax, Plasmodium ovale, and Plasmodium malariae. Arquin 250mg Syrup is not effective against Plasmodium falciparum. Besides this, it also treats amoebiasis (intestinal dysentery) and rheumatic disease (arthritis).
Arquin 250mg Syrup works by preventing the formation of the nontoxic heme metabolite hemozoin by the parasite. Due to this, the parasite dies from its own toxic by-products released due to haemoglobin's metabolism.
The use of Arquin 250mg Syrup is not allowed in persons who are already taking any antibiotic (azithromycin) as it may cause dangerous effects on the heart.
No such effect has been reported yet. Always consult your doctor for the change of dose regimen or an alternative medicine if needed.
No such harmful interaction has been reported in patients who take this drug under strict doctors' surveillance. However, some patients might experience eye (retina) damage and cause pounding heart, so patient taking Arquin 250mg Syrup is advised to consult a doctor and have regular check-ups cyclically.
There may be a risk of hemolysis in patients with G6PD deficiency while using Arquin 250mg Syrup. Doctor's consultation is mandatory before you start this medication.

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