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About Leoquin EC 250 Tablet
Leoquin EC 250 Tablet belongs to the class of medications called 'quinoline' primarily used to treat malaria. Leoquin EC 250 Tablet gives a degree of protection (prophylaxis) against malaria when people travel to areas where malarial cases exist. It is effective against Plasmodium vivax, Plasmodium ovale, and Plasmodium malariae. Leoquin EC 250 Tablet is not effective against Plasmodium falciparum. Besides this, it also treats amoebiasis (intestinal dysentery) and rheumatic disease (arthritis).
Leoquin EC 250 Tablet contains 'chloroquine' which acts by killing the malarial parasites, i.e. Plasmodium and stops the formation of the nontoxic heme metabolite hemozoin by the parasite. Heme part of the red blood cells is broken by the malarial, causing parasites. Leoquin EC 250 Tablet prevents the breakdown of heme part and is actually toxic to the parasite. It kills the parasitic form living in red blood cells that resides in the liver.
Leoquin EC 250 Tablet should be taken as prescribed by your doctor. The dose of Leoquin EC 250 Tablet can vary depending upon your condition and the severity of the infection. The common side effects of Leoquin EC 250 Tablet include vomiting, nausea, hair loss and itchy skin. Everyone need not experience the above side effects. In case of any discomfort, speak with a doctor.
Before starting Leoquin EC 250 Tablet , please inform your doctor if you are allergic to chloroquine or have kidney or liver problems. Do not take Leoquin EC 250 Tablet on your own. Leoquin EC 250 Tablet is safe to use during pregnancy and breastfeeding. Prolonged use of Leoquin EC 250 Tablet may have a severe risk on the heart and retina of the eyes leading to pounding heartbeats and permanent vision problems.
Uses of Leoquin EC 250 Tablet
Medicinal Benefits
Leoquin EC 250 Tablet falls into a group of medicines known as antimalarials, indicated for treating or preventing malaria. Leoquin EC 250 Tablet contains chloroquine, which belongs to quinoline. It works by preventing the formation of the nontoxic heme metabolite hemozoin by the parasite. Due to this, the parasite dies from its own toxic by-products released due to haemoglobin's metabolism. Leoquin EC 250 Tablet is also indicated for the treatment of rheumatoid arthritis and autoimmune diseases like lupus and intestinal infection caused by amoeba (amoebiasis).
Side Effects of Leoquin EC 250 Tablet
Directions for Use
Storage
Drug Warnings
Leoquin EC 250 Tablet does not respond well against all malaria strains, so consult with your doctor if you do not respond well to Leoquin EC 250 Tablet . This medicine can affect heart health, especially if a person is taking medications, including the antibiotic azithromycin and anticancer like tamoxifen. An individual must consult with the doctor if they are noticing fast or pounding heartbeats and sudden dizziness. This medicine cannot be used for a long duration as it may cause irreversible damage to the eye that could lead to vision problems. Leoquin EC 250 Tablet cannot be used in persons who have heart disease, heart rhythm disorder, diabetes, a stomach disorder, an allergy to quinine, liver or kidney disease, psoriasis, alcoholism, porphyria (a genetic enzyme disorder that affects the skin or nervous system), a genetic enzyme deficiency called glucose-6-phosphate dehydrogenase (G6PD) deficiency. Consult with your doctor if you are pregnant or breastfeeding as this medicine could only be used if prescribed by the doctor.
Therapeutic Class
Drug-Drug Interactions
Drug-Food Interactions
Diet & Lifestyle Advise
Habit Forming
How Leoquin EC 250 Tablet Works
What if I have taken an overdose of Leoquin EC 250 Tablet
Alcohol
Caution
No serious interaction has been reported between alcohol and Leoquin EC 250 Tablet yet alcohol should be avoided with Leoquin EC 250 Tablet as it aggravates side effects.
Pregnancy
Caution
Leoquin EC 250 Tablet should be used with caution and can only be used in pregnancy if recommended by the doctor.
Breast Feeding
Caution
It is not safe to breastfeed while taking Leoquin EC 250 Tablet as this medicine can pass into breast milk. A patient is advised to take this drug only on doctor's consultation.
Driving
Caution
Leoquin EC 250 Tablet may cause blurred vision, so one should avoid driving or doing any activity that needs mental alertness. A patient is thus advised to take this drug only on doctor's consultation.
Liver
Caution
Leoquin EC 250 Tablet therapy is unlikely to cause liver injury in normal individuals but can trigger an acute worsening of porphyria in rare cases. Thus doctor's consultation is recommended before taking Leoquin EC 250 Tablet .
Kidney
Caution
Leoquin EC 250 Tablet administration impairs kidney function in a few cases, so a patient is recommended to consult a doctor before taking Leoquin EC 250 Tablet .
Children
Safe if prescribed
Leoquin EC 250 Tablet is safe to use in children, yet dose adjustment by a doctor will be done on the basis of age, weight, and severity of the infection.
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