Isentress 400mg Tablet belongs to the group of medicines called antiretroviral agents used to treat HIV infection. HIV (Human Immunodeficiency Virus) is a virus that attacks the immune system and destroys the white blood cells that help in fighting infection, making the individual susceptible to other infections or illnesses.

Isentress 400mg Tablet contains 'Raltegravir' which is a human immunodeficiency virus integrase strand transfer inhibitor (HIV-1 INSTI). It works by inhibiting the replication of HIV by blocking DNA integration into new cells. Thus, Isentress 400mg Tablet is effective in controlling the HIV from multiplying and is used in the treatment of HIV.

Take Isentress 400mg Tablet in the dose and duration prescribed by the doctor. Isentress 400mg Tablet may cause certain side effects such as nausea, tiredness, insomnia, headache and dizziness. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if these side effects persist. 

Inform the doctor if you are allergic to any of the components of Isentress 400mg Tablet. Isentress 400mg Tablet may cause dizziness, so drive with caution. Isentress 400mg Tablet is not recommended during pregnancy or breastfeeding. Avoid alcohol consumption as it might cause increased dizziness. It is important to practise safe sex to avoid transmitting HIV to your partner.

Isentress 400mg Tablet contains 'Raltegravir' which is a human immunodeficiency virus integrase strand transfer inhibitor (HIV-1 INSTI). It works by inhibiting the replication of HIV by blocking DNA integration into new cells. Thus, Isentress 400mg Tablet is effective in controlling the HIV from multiplying and is used in the treatment of HIV in adults and children weighing at least 2kgs. Isentress 400mg Tablet may decrease the chance of developing AIDS and HIV related illnesses like serious infections or cancer.

• Headache
• Dizziness
• Nausea
• Tiredness
• Insomnia (sleeping problems)

Inform the doctor if you are allergic to any of the components of Isentress 400mg Tablet. Use Isentress 400mg Tablet with caution in case of mental health problems, bone problems, liver problems, skin problems, infections and muscle problems. Keep your doctor informed if you have a history of hypertension, diabetes, hepatitis, liver disease, kidney problems or heart disease. Offer a detailed medical and vaccination history. Inform the doctor especially if you are on any antidepressants, antacids, iron supplements, radiotherapy, analgesics, heart medicines, antibiotics, anti-epileptics, antifungals or any other antiretrovirals. Isentress 400mg Tablet is not recommended during pregnancy and breastfeeding. Avoid Isentress 400mg Tablet use with alcohol. It is important to practise safe sex to avoid transmitting HIV to your partner.

Drug-Drug Interactions: Isentress 400mg Tablet may interact with antiviral/anti-HIV drug (atazanavir, ritonavir, tipranavir), anti-Tb drug (rifampicin), antidepressant (St John’s wort), iron supplements, antacids and anti-obesity drug (orlistat).

Drug-Food Interactions: No interactions found.

Drug-Disease Interactions: Isentress 400mg Tablet should be used with caution in patients with mental health problems, bone problems, liver problems, skin problems, infections and muscle problems.

• ATAZANAVIR
• RITONAVIR
• TIPRANAVIR
• RIFAMPICIN
• IRON
• ORLISTAT
• ST JOHN'S WORT

• Practise safe sex to prevent transmitting HIV to your partner. Educate yourself and your partner about pre and post-exposure prophylaxis and ART (anti-retroviral therapy).
• Meditation and yoga have also proven very effective in helping HIV patients maintain a healthy attitude and body.
• Eat more lean meats, healthy fats, fruits, vegetables and whole-grain foods.
• Taking a stroll in the garden, or spending 30 minutes of your time doing some light physical activity can be very useful. However, do not over-exert yourself if you feel too tired. 

• Discuss contraception with your doctor while taking Isentress 400mg Tablet.
• People on treatment with Isentress 400mg Tablet should use additional contraception (barrier method such as condoms) while taking Isentress 400mg Tablet.

HIV infection: HIV (Human Immunodeficiency Virus) is a virus that attacks the immune system and destroys the white blood cells that help in fighting infection, making the individual susceptible to other infections or illnesses. People with HIV experience flu-like symptoms such as fever, chills, rash, night sweats, muscle aches, tiredness, and sore throat. These symptoms usually last for days to several weeks. It spreads through body fluids such as semen, vaginal fluid, and blood. If left untreated, this condition can lead to AIDS (Acquired Immunodeficiency Syndrome). It is a life-long condition, and there is no definite cure for it. However, it can be controlled by treating with antiretroviral drugs.