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RALTEGRAVIR

About

RALTEGRAVIR belongs to the group of medicines called antiretroviral agents used to treat HIV infection. HIV (Human Immunodeficiency Virus) is a virus that attacks the immune system and destroys the white blood cells that help in fighting infection, making the individual susceptible to other infections or illnesses.

RALTEGRAVIR contains 'Raltegravir' which is a human immunodeficiency virus integrase strand transfer inhibitor (HIV-1 INSTI). It works by inhibiting the replication of HIV by blocking DNA integration into new cells. Thus, RALTEGRAVIR is effective in controlling the HIV from multiplying and is used in the treatment of HIV.

Take RALTEGRAVIR in the dose and duration prescribed by the doctor. RALTEGRAVIR may cause certain side effects such as nausea, tiredness, insomnia, headache and dizziness. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if these side effects persist. 

Inform the doctor if you are allergic to any of the components of RALTEGRAVIR. RALTEGRAVIR may cause dizziness, so drive with caution. RALTEGRAVIR is not recommended during pregnancy or breastfeeding. Avoid alcohol consumption as it might cause increased dizziness. It is important to practise safe sex to avoid transmitting HIV to your partner.

Uses of RALTEGRAVIR

Treatment of HIV infection

Medicinal Benefits

RALTEGRAVIR contains 'Raltegravir' which is a human immunodeficiency virus integrase strand transfer inhibitor (HIV-1 INSTI). It works by inhibiting the replication of HIV by blocking DNA integration into new cells. Thus, RALTEGRAVIR is effective in controlling the HIV from multiplying and is used in the treatment of HIV in adults and children weighing at least 2kgs. RALTEGRAVIR may decrease the chance of developing AIDS and HIV related illnesses like serious infections or cancer.

Directions for Use

Tablet: Swallow it as a whole with water. Do not crush or chew the tablet. Chewable tablet: Chew the tablet completely before swallowing. Suspension: Take the prescribed dose by mouth using the measuring cup provided by the pack.

Storage

Store in a cool and dry place away from sunlight

Side Effects of RALTEGRAVIR

  • Headache
  • Dizziness
  • Nausea
  • Tiredness
  • Insomnia (sleeping problems)

In-Depth Precautions and Warning

Drug Warnings

Inform the doctor if you are allergic to any of the components of RALTEGRAVIR. Use RALTEGRAVIR with caution in case of mental health problems, bone problems, liver problems, skin problems, infections and muscle problems. Keep your doctor informed if you have a history of hypertension, diabetes, hepatitis, liver disease, kidney problems or heart disease. Offer a detailed medical and vaccination history. Inform the doctor especially if you are on any antidepressants, antacids, iron supplements, radiotherapy, analgesics, heart medicines, antibiotics, anti-epileptics, antifungals or any other antiretrovirals. RALTEGRAVIR is not recommended during pregnancy and breastfeeding. Avoid RALTEGRAVIR use with alcohol. It is important to practise safe sex to avoid transmitting HIV to your partner.

Drug Interactions

Drug-Drug Interactions: RALTEGRAVIR may interact with antiviral/anti-HIV drug (atazanavir, ritonavir, tipranavir), anti-Tb drug (rifampicin), antidepressant (St John’s wort), iron supplements, antacids and anti-obesity drug (orlistat).

Drug-Food Interactions: No interactions found.

Drug-Disease Interactions: RALTEGRAVIR should be used with caution in patients with mental health problems, bone problems, liver problems, skin problems, infections and muscle problems.

Drug-Drug Interactions Checker List:

  • ATAZANAVIR
  • RITONAVIR
  • TIPRANAVIR
  • RIFAMPICIN
  • IRON
  • ORLISTAT
  • ST JOHN'S WORT
  • Safety Advice

    • Safety Warning

      Alcohol

      unsafe

      It is not recommended to use alcohol with RALTEGRAVIR. Please consult your doctor if you have any concerns.

    • Safety Warning

      Pregnancy

      unsafe

      Avoid using RALTEGRAVIR if pregnant. In case of any concerns, consult your doctor.

    • Safety Warning

      Breast Feeding

      unsafe

      Avoid breastfeeding while taking RALTEGRAVIR. In case of any concerns, consult your doctor.

    • Safety Warning

      Driving

      caution

      RALTEGRAVIR may cause tiredness and dizziness, which may affect your ability to drive. Do not drive if you experience any side effects after using RALTEGRAVIR.

    • Safety Warning

      Liver

      caution

      Exercise caution before using RALTEGRAVIR in case of liver disease as it can derange liver enzymes. Please consult your doctor to address any concerns.

    • Safety Warning

      Kidney

      caution

      Exercise caution before using RALTEGRAVIR in case of established kidney disease. Please consult your doctor to address any concerns.

    • Safety Warning

      Children

      caution

      RALTEGRAVIR is not recommended for use in children below 2years as the safety and effectiveness have not been established.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Practise safe sex to prevent transmitting HIV to your partner. Educate yourself and your partner about pre and post-exposure prophylaxis and ART (anti-retroviral therapy).
    • Meditation and yoga have also proven very effective in helping HIV patients maintain a healthy attitude and body.
    • Eat more lean meats, healthy fats, fruits, vegetables and whole-grain foods.
    • Taking a stroll in the garden, or spending 30 minutes of your time doing some light physical activity can be very useful. However, do not over-exert yourself if you feel too tired. 

    Special Advise

    • Discuss contraception with your doctor while taking RALTEGRAVIR.
    • People on treatment with RALTEGRAVIR should use additional contraception (barrier method such as condoms) while taking RALTEGRAVIR.

    Patients Concern

    Disease/Condition Glossary

    HIV infection: HIV (Human Immunodeficiency Virus) is a virus that attacks the immune system and destroys the white blood cells that help in fighting infection, making the individual susceptible to other infections or illnesses. People with HIV experience flu-like symptoms such as fever, chills, rash, night sweats, muscle aches, tiredness, and sore throat. These symptoms usually last for days to several weeks. It spreads through body fluids such as semen, vaginal fluid, and blood. If left untreated, this condition can lead to AIDS (Acquired Immunodeficiency Syndrome). It is a life-long condition, and there is no definite cure for it. However, it can be controlled by treating with antiretroviral drugs.

    FAQs

    RALTEGRAVIR belongs to the group of medicines called antiretroviral agents used to treat HIV infection.

    RALTEGRAVIR works by inhibiting the replication of viral DNA and by preventing it from being integrated in the human body.

    Do not stop taking RALTEGRAVIR without consulting your doctor as it may reduce the effectiveness of anti-HIV therapy. Continue taking RALTEGRAVIR for as long as your doctor has prescribed it to you to treat your condition effectually. Do not be reluctant to speak with your doctor if you experience any difficulty while taking RALTEGRAVIR.

    If you miss a dose, take it as soon as you remember. However, if it is almost time for the scheduled dose, skip the missed dose and take the scheduled dose.

    RALTEGRAVIR does not cure HIV infection. RALTEGRAVIR reduces the activity of HIV in the body and improves the functioning of the immune system. RALTEGRAVIR may decrease the chance of developing AIDS and HIV related illnesses like serious infections or cancer.

    Not enough studies are available to ascertain the effects of RALTEGRAVIR on fertility. Please consult your doctor in case of any concerns.

    Available Medicines for

    RALTEGRAVIR

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