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Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Hertab Tablet is an anti-cancer medicine used in the treatment of Breast cancer. It contains Lapatinib, which works by inhibiting the excess production of a human epidermal growth factor receptor 2 (HER2) protein in the mammalian cells; this causes inhibition of the cancer cell growth and, finally, initiation of apoptosis. It is known to cause embryo-fetal toxicity. Hence, if you are pregnant or breastfeeding, inform your doctor beforehand.

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Whats That

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Composition :

LAPATINIB-250MG

Manufacturer/Marketer :

Hetero Drugs Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Hertab Tablet

Hertab Tablet is an anti-cancer medicine used in the treatment of Breast cancer. The abnormal growth of cancer (malignant) cells in the breast is known as breast cancer. Hertab Tablet is used in combination with capecitabine for treating patients with HER2-positive advanced or metastatic breast cancer who have received prior treatment, including anthracycline, taxane, and trastuzumab. This medicine is also used in combination with letrozole for the treatment of hormone receptor-positive metastatic breast cancer in patients with HER2-positive (human epidermal growth factor receptor 2) for whom hormonal therapy is indicated.

Hertab Tablet contains Lapatinib as an active ingredient which belongs to the class of kinase inhibitors. It works by inhibiting the excess production of a human epidermal growth factor receptor 2 (HER2) protein in the mammalian cells. This causes inhibition of the cancer cell growth and, finally, initiation of apoptosis.

Hertab Tablet may cause certain side effects such as diarrhea, fatigue, nausea, rash, indigestion, loss of appetite, headache, vomiting, weakness, mouth sores, hair loss, dry skin, myalgia, and allergic reactions. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor. Hertab Tablet should be taken as advised by your doctor. Take the medicine around the same time daily. Do not skip any dose; if you forget any dose, try to take it as soon as you remember unless it is time for your next dose. Do not double the dose.

Hertab Tablet should be avoided if you are allergic to it or any other components of this medicine. Before starting the treatment, let your doctor know about your complete medical history and medication history, including vitamin and herbal supplements. Inform your doctor if you have any cardiovascular conditions or liver/kidney disease before taking Hertab Tablet . Hertab Tablet is known to cause embryo-fetal toxicity. Hence, if you are pregnant or breastfeeding, inform your doctor beforehand. 

Uses of Hertab Tablet

Treatment of Breast Cancer

Directions for Use

Take Hertab Tablet as prescribed by your doctor. It should be taken one hour before or at least one hour after. Swallow the medicine as a whole with a glass of water. Do not chew, crush, or break the medicine.

Medicinal Benefits

Hertab Tablet contains Lapatinib as an active ingredient, which is used in combination with capecitabine for treating patients with HER2-positive advanced or metastatic breast cancer who have received prior treatment. This medicine works by inhibiting the excess production of a human epidermal growth factor receptor 2 (HER2) protein in the mammalian cells. This causes inhibition of the cancer cell growth and, finally, initiation of apoptosis.

How Hertab Tablet Works

Hertab Tablet contains Lapatinib as an active ingredient which belongs to the class of kinase inhibitors. It works by inhibiting the excess production of a human epidermal growth factor receptor 2 (HER2) protein in the mammalian cells. This causes inhibition of the cancer cell growth and, finally, initiation of apoptosis.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Hertab Tablet

  • Nausea
  • Vomiting
  • Diarrhoea
  • Myalgia
  • Dry skin
  • Hair loss
  • Tiredness
  • Weakness
  • Headache
  • Fatigue

What if I have taken an overdose of Hertab Tablet

Please do not exceed the recommended dose, as it might cause an overdose. Signs and symptoms of an overdose of Hertab Tablet may include severe diarrhea/vomiting. Seek immediate medical attention if you observe any symptoms or think you have taken too much. Do this even if there are no signs of discomfort or poisoning.

Drug Warnings

Hertab Tablet should be avoided if you are allergic to it or any other components of this medicine. Inform your doctor if you have any cardiovascular conditions or liver/kidney disease, as it can cause adverse effects. Hertab Tablet may cause left ventricular ejection fraction, prolonged QT interval, hepatotoxicity, interstitial lung disease, pneumonitis, severe diarrhoea, and hypersensitivity reactions during the treatment. Hence, careful observation should be performed for any reactions in the patient. If any changes or hypersensitivity reactions occur, treatment should be discontinued. Hertab Tablet is known to cause embryo-fetal toxicity. Hence, if you are pregnant or planning to become pregnant, inform your doctor beforehand. Breastfeeding should be discontinued in nursing mothers during the treatment. Hertab Tablet should be given to children only if prescribed by the paediatrician. Hertab Tablet is not recommended for use in children as the safety and efficacy are not established. Avoid alcohol consumption and smoking, as it can lead to serious adverse effects.

Drug-Drug Interactions

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LapatinibColchicine
Severe
LapatinibItraconazole
Severe

Drug-Drug Interactions

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LapatinibColchicine
Severe
How does the drug interact with Hertab Tablet 150's:
Coadministration of colchicine with Hertab Tablet 150's results in increased colchicine levels in the blood, increasing the risk of serious side effects

How to manage the interaction:
Although taking Colchicine and Hertab Tablet 150's together may possibly result in an interaction, they can be taken together if your doctor prescribes it. However, if you experience abdominal pain, numbness or tingling in your hands and legs, muscle pain, or weakness, contact your doctor immediately. Do not discontinue any medication without consulting your doctor.
LapatinibItraconazole
Severe
How does the drug interact with Hertab Tablet 150's:
Using Hertab Tablet 150's together with itraconazole may significantly increase the blood levels of Hertab Tablet 150's.

How to manage the interaction:
Hertab Tablet 150's and itraconazole may interact, but if a doctor prescribes them, you can still use them. If you have a fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, fatigue, nausea, vomiting, dark urine, light stools, and yellowing of the skin or eyes, diarrhoea, dizziness, lightheadedness, fainting, shortness of breath, or rapid or pounding heartbeats, seek medical attention. Never discontinue taking a medication without consulting a doctor.
LapatinibPosaconazole
Severe
How does the drug interact with Hertab Tablet 150's:
Taking Hertab Tablet 150's with posaconazole can increase the levels of Hertab Tablet 150's in the blood, which can lead to an increased risk of side effects such as diarrhea, liver problems, and heart problems.

How to manage the interaction:
Although using Posaconazole and Hertab Tablet 150's together can result in an interaction, they can be taken together if advised by your doctor. However, contact a doctor if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, light colored stools, and/or yellowing of the skin or eyes. Do not stop taking any medications without consulting a doctor.
LapatinibAmiodarone
Severe
How does the drug interact with Hertab Tablet 150's:
Coadministration of Amiodarone together with Hertab Tablet 150's may raise the risk of an abnormal heart rhythm.

How to manage the interaction:
Even though Amiodarone and Hertab Tablet 150's interact, they can be used if prescribed by a doctor. If you have cardiac problems or electrolyte imbalances, you may be at greater risk. If you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, get medical attention. Do not discontinue any medications without consulting a doctor.
LapatinibCeritinib
Severe
How does the drug interact with Hertab Tablet 150's:
Taking Hertab Tablet 150's with ceritinib may significantly increase the blood levels of Hertab Tablet 150's. This can make you more likely to develop side effects such as diarrhea and liver problems.

How to manage the interaction:
Co-administration of Ceritinib with Hertab Tablet 150's can possibly result in an interaction, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
LapatinibGatifloxacin
Severe
How does the drug interact with Hertab Tablet 150's:
Taking Gatifloxacin and Hertab Tablet 150's can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Gatifloxacin and Hertab Tablet 150's together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
LapatinibNilotinib
Severe
How does the drug interact with Hertab Tablet 150's:
Combining Hertab Tablet 150's and nilotinib can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Hertab Tablet 150's and nilotinib together can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, diarrhea, or vomiting, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
LapatinibClozapine
Severe
How does the drug interact with Hertab Tablet 150's:
When Clozapine is taken with Hertab Tablet 150's, can increase the risk of neutropenia (low white blood count).

How to manage the interaction:
Taking Clozapine with Hertab Tablet 150's together can possibly result in an interaction, but it can be taken if a doctor has advised it. If you have any of these symptoms, it's important to contact a doctor right away. You may also experience fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, weight loss, pain, sudden dizziness, feeling lightheaded, fainting, or heart palpitations. Do not discontinue any medications without consulting a doctor.
LapatinibMoxifloxacin
Severe
How does the drug interact with Hertab Tablet 150's:
Using Moxifloxacin together with Hertab Tablet 150's can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although there is a possible interaction between Moxifloxacin and Hertab Tablet 150's, you can take these medicines together if prescribed by a doctor. If you experience irregular heart rhythm, dizziness, difficulty breathing, it is important to contact a doctor right away. Do not stop using any medications without a doctor's advice.
LapatinibPazopanib
Severe
How does the drug interact with Hertab Tablet 150's:
Taking Pazopanib with Hertab Tablet 150's may significantly increase the blood levels of pazopanib. This can make you more likely to develop serious side effects such as liver problems, irregular heart rhythm, bleeding and high blood pressure,

How to manage the interaction:
Taking Pazopanib with Hertab Tablet 150's together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, fast or pounding heartbeats, chest pain or tightness, pain in your arms, back, neck, or jaw, shortness of breath, numbness or weakness on one side of your body, and difficulty speaking. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Meditation and yoga have been proven very effective in helping cancer patients maintain a healthy attitude and body.
  • Eat more lean meats, healthy fats, fruits, vegetables, and whole-grain foods to give you more energy. 
  • Stay hydrated by drinking plenty of water, as dehydration is often seen in cancers.
  • Taking a stroll in the garden or spending 30 minutes of your time doing some light physical activity can be very useful. However, do not over-exert yourself if you feel too tired. 
  • Avoid smoking and alcohol consumption.

Habit Forming

No

Therapeutic Class

ANTINEOPLASTIC

Hertab Tablet Substitute

Substitutes safety advice
  • Tykerb 250 mg Tablet 30's

    by AYUR

    275.50per tablet
  • Herduo Tablet 30's

    164.00per tablet
  • Combinib 250Mg Tablet 30'S

    by AYUR

    224.90per tablet
  • HerTablet 250mg Tablet 30's

    by AYUR

    178.90per tablet
  • Herduo 250Mg Tablet 150'S

    by AYUR

    163.45per tablet
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Alcohol

Unsafe

Alcohol intake might increase the risk of worsening your condition. Hence, avoid alcohol consumption till your condition improves.

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Pregnancy

Unsafe

Hertab Tablet is not recommended for use in pregnancy as it may harm your foetus. Hence, if you are pregnant or planning pregnancy, inform your doctor before taking Hertab Tablet . Use reliable methods of birth control while on treatment with Hertab Tablet .

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Breast Feeding

Unsafe

Avoid nursing your child while on treatment with Hertab Tablet as it can cause serious side effects to the newborn baby.

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Driving

Consult your doctor

It is unknown whether Hertab Tablet will affect your mental ability to drive or operate machines. Hence, consult your doctor for information regarding this.

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Liver

Caution

Inform your doctor if you have any pre-existing liver disease. Your doctor may adjust the dose of the medicine based on the condition. Hertab Tablet is known to cause hepatotoxicity in some patients. If you notice any reactions such as itching, yellowing of the skin or eyes, dark urine, abdominal pain, unusual bleeding, or pale or dark stools, discontinue the treatment and inform your doctor immediately.

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Kidney

Caution

Limited data are available on the effect of Hertab Tablet in kidney-impaired patients. Hence, if you have a pre-existing or a history of kidney disease, inform your doctor.

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Children

Unsafe

Hertab Tablet is not recommended for use in children as the safety and efficacy are not established.

FAQs

Hertab Tablet is used to treat breast cancer.
Hertab Tablet contains Lapatinib, which works by inhibiting the excess production of a protein called human epidermal growth factor receptor 2 (HER2) in mammalian cells. This causes inhibition of the cancer cell growth.
Inform your doctor whether you have received any other breast cancer treatment. Hertab Tablet may cause left ventricular ejection fraction, hypersensitivity reactions, hepatotoxicity, severe diarrhea, and embryo-fetal toxicity during the treatment. Hence, inform your oncologist if you have any cardiovascular conditions, liver/kidney disease, are pregnant, are planning to become pregnant, or are breastfeeding before taking Hertab Tablet .
Hepatotoxicity (liver toxicity) has been reported in clinical studies and postmarketing experience with Hertab Tablet . Hepatotoxicity can be fatal, and deaths have been reported. The cause of death is unknown. If you have upper stomach pain, itching, dark urine, clay-coloured faeces, or jaundice (yellowing of the skin or eyes), inform your doctor immediately.
Hertab Tablet may cause side effects such as diarrhoea, fatigue, nausea, rash, indigestion, loss of appetite, headache, vomiting, weakness, mouth sores, hair loss, dry skin, myalgia, and allergic reactions. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor.
Hertab Tablet is an anti-cancer medicine used in the treatment of breast cancer.
Yes, Hertab Tablet can be given in combination with other anti-cancer drugs if prescribed by the doctor. Talk to the doctor if you have any concerns.
Swallow the medicine as a whole with a glass of water. Do not chew, crush, or break the medicine. It should be taken one hour before or at least one hour after food.
Drink enough fluids and eat fibre-rich food if you experience diarrhoea. Consult the doctor if the diarrhoea persists or worsens.
Use sunscreen, soap-free cleanser and products that are free from fragrance and are hypoallergenic. Get your skin checked regularly by the doctor during treatment with Hertab Tablet .
Before starting Hertab Tablet , the doctor may advise heart and liver function tests.
Consult the doctor if you are planning for pregnancy after treatment with Hertab Tablet . Use effective contraception during treatment with Hertab Tablet and for a week after the last dose.

Country of origin

India

Manufacturer/Marketer address

2Nd Floor, 8-3-166/7/1 Erragadda, Hyderabad-500018
Other Info - HER0206

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