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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 9, 2024 | 12:38 PM IST
Glycoaish N 0.5mg/2.5mg Injection is used to reverse the effects of muscle relaxants and anaesthesia medicines used during surgery. It contains Glycopyrrolate and Neostigmine which increase the level of an enzyme that is involved in transmission between nerve impulses and muscle movements. In some cases, this medicine may cause side effects such as constipation, dry mouth, nausea, vomiting, dizziness, diarrhoea, and dry skin. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Manufacturer/Marketer

Aishwarya Healthcare

Consume Type

PARENTERAL

Return Policy

Not Returnable

for this medicine

About Glycoaish N 0.5mg/2.5mg Injection

Glycoaish N 0.5mg/2.5mg Injection belongs to a group of medicines called 'anticholinesterase agents/acetylcholinesterase inhibitors', primarily used to reverse the effects of muscle relaxant and anesthesia medicines used during surgery. Certain medicines like propofol, etomidate, ketamine which is an anesthetic medicine cause anesthesia (sedative action) during surgery. Several muscles relaxant medicines are also used during surgery like vecuronium, rocuronium relaxes the muscles during surgery.

Glycoaish N 0.5mg/2.5mg Injection contains two medicines namely: Glycopyrrolate and Neostigmine. Neostigmine increases levels of a substance known as acetylcholine by stopping an enzyme required for the breakdown of acetylcholine involved in transmission between nerve impulses and muscle movements. It is used at the end of surgery to reverse the effects of several medicines used during surgery like anesthetics and muscle relaxants. Glycopyrrolate is an anticholinergic It works by blocking the activity of a chemical messenger (acetylcholine) in the brain. It is added to avoid the unwanted effects of Neostigmine like stomach acid, excess saliva production and decreased heart rate.

 You are advised to take Glycoaish N 0.5mg/2.5mg Injection for as long as your doctor has prescribed it for you depending on your medical condition.  Some people may experience constipation, dry mouth, nausea, vomiting, visual disturbance, dizziness, diarrhea, too much saliva, dryness of skin, increased pressure of the eye, stomach cramps, the uncontrolled need of passing urine. Most of these side effects of Glycoaish N 0.5mg/2.5mg Injection do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Do not use Glycoaish N 0.5mg/2.5mg Injection if you are allergic to Glycoaish N 0.5mg/2.5mg Injection or any of its contents. Glycoaish N 0.5mg/2.5mg Injection should not be taken if you have difficulty in passing urine and blockage in the intestine. Glycoaish N 0.5mg/2.5mg Injection should not be taken in the conditions like asthma, kidney disease and heart disease. If you are pregnant or breastfeeding, it is advised to inform your doctor before using Glycoaish N 0.5mg/2.5mg Injection. It is not recommended to drive after taking Glycoaish N 0.5mg/2.5mg Injection as it may cause your eyesight to become week. Glycoaish N 0.5mg/2.5mg Injection can be given to children if prescribed by the doctor, the dose depends on the child’s age and weight.

Uses of Glycoaish N 0.5mg/2.5mg Injection

Used to reverse the effects of muscle relaxant and anesthesia medicines at the end of surgery.

Medicinal Benefits

Glycoaish N 0.5mg/2.5mg Injection contains two medicines namely: Glycopyrrolate and Neostigmine. It is primarily used to reverse the effects of muscle relaxant and anesthesia medicines at the end of surgery. Neostigmine increases levels of a substance known as acetylcholine by stopping an enzyme required for the breakdown of acetylcholine involved in transmission between nerve impulses and muscle movements. It is used at the end of surgery to reverse the effects of several medicines used during surgery like anesthetics and muscle relaxants. Glycopyrrolate is an anticholinergic It works by blocking the activity of a chemical messenger (acetylcholine) in the brain. It is added to avoid the unwanted effects of Neostigmine like stomach acid, excess saliva production and decreased heart rate.

Directions for Use

It will be administered by a healthcare professional; do not self-administer.

Side Effects of Glycoaish N 0.5mg/2.5mg Injection

  • Constipation
  • Dry mouth
  • Nausea
  • Vomiting
  • Visual disturbance
  • Dizziness
  • Diarrhea
  • Too much saliva
  • Dryness of skin
  • Increased pressure of the eye
  • Stomach cramps
  • Uncontrolled need of passing urine

Drug Warnings

Let your doctor know if you use any other medicines or supplements before using Glycoaish N 0.5mg/2.5mg Injection. Do not use Glycoaish N 0.5mg/2.5mg Injection if you are allergic to Glycoaish N 0.5mg/2.5mg Injection or any of its contents. Glycoaish N 0.5mg/2.5mg Injection should not be taken if you have difficulty in passing urine and blockage in the intestine. Glycoaish N 0.5mg/2.5mg Injection should not be taken in the conditions like asthma, breathing difficulties, stomach ulcers, high blood pressure, high temperature (fever), kidney disease, and heart disease. Before taking Glycoaish N 0.5mg/2.5mg Injection inform your doctor if you have muscle weakness (myasthenia gravis), fit disorder, parkinson’s disease, enlarged prostate gland, abdominal pain and vomiting. If you are pregnant or breastfeeding, it is advised to inform your doctor before using Glycoaish N 0.5mg/2.5mg Injection. It is not recommended to drive after taking Glycoaish N 0.5mg/2.5mg Injection as it may cause your eyesight to become week. Glycoaish N 0.5mg/2.5mg Injection can be given to children if prescribed by the doctor; the dose depends on the child’s age and weight.

Drug Interactions

Drug-Drug Interaction: Glycoaish N 0.5mg/2.5mg Injection may interact with antidepressants (lithium, amitriptyline, imipramine), medicines used for mental illness (clozapine), pain killers (nefopam), antiviral (amantadine), muscle relaxants (suxamethonium), antibiotics (gentamicin, streptomycin, cholistimethate sodium), medicines for heart disease (procainamide, propafenone, quinidine), antimalarial (chloroquine), a medicine used in migraine (propranolol).

Drug-Food Interaction: Do not consume alcohol while taking Glycoaish N 0.5mg/2.5mg Injection as it could lead to increased dizziness and weak eyesight.

Drug-Disease Interaction: Glycoaish N 0.5mg/2.5mg Injection may have interactions with asthma, muscle weakness, stomach ulcers, high blood pressure, high temperature (fever), kidney disease, and heart disease

Drug-Drug Interactions Checker List

  • LITHIUM
  • AMITRIPTYLINE
  • IMIPRAMINE
  • CLOZAPINE
  • AMANTADINE
  • SUXAMETHONIUM
  • GENTAMICIN
  • STREPTOMYCIN
  • PROCAINAMIDE
  • PROPAFENONE
  • QUINIDINE
  • CHLOROQUINE
  • PROPRANOLOL

Habit Forming

No

Diet & Lifestyle Advise

  • Maintain proper weight by following a healthy diet.
  • Avoid smoking and alcohol consumption.
  • Try to avoid stress by practising meditation or yoga.
  • Include fruits and vegetables in your diet as they contain anti-oxidants.
  • Limit foods with high cholesterol and saturated fats.
  • Cut down on sugar, salt and processed foods.
  • Drink plenty of water.

Special Advise

Do not use Glycoaish N 0.5mg/2.5mg Injection on your own, it is given only by a doctor.

Disease/Condition Glossary

Anesthesia is the use of medicines to avoid pain during surgery. These medicines are known as anesthetics. They may be given by injection, inhalation, topical lotion, spray, eye drops or skin patch. They cause you to have a loss of awareness or feeling. Specific medicines like propofol, etomidate, ketamine which is an anesthetic medicine cause anesthesia (sedative action) during surgery. Several muscles relaxant medicines are also used during surgery like vecuronium, rocuronium relaxes the muscles during surgery.

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Alcohol

Unsafe

Avoid consuming alcohol while taking Glycoaish N 0.5mg/2.5mg Injection as it may cause increased dizziness.

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Pregnancy

Caution

Glycoaish N 0.5mg/2.5mg Injection contains neostigmine which is a pregnancy category C drug. It may be unsafe to use during pregnancy since animal studies of Glycoaish N 0.5mg/2.5mg Injection showed harmful effects on the fetus. Please consult your doctor before taking Glycoaish N 0.5mg/2.5mg Injection if you are pregnant or planning to conceive.

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Breast Feeding

Caution

It is not known if Glycoaish N 0.5mg/2.5mg Injection is excreted into the breast milk. Please consult your doctor before taking Glycoaish N 0.5mg/2.5mg Injection if you are a breastfeeding mother.

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Driving

Unsafe

Glycoaish N 0.5mg/2.5mg Injection can make you feel dizzy, eyesight becomes a week and affect your ability to drive. It is advised not to drive or operate machinery while using Glycoaish N 0.5mg/2.5mg Injection if you are not mentally alert and focused.

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Liver

Caution

If u have or had a history or evidence of any liver-related diseases, please consult the doctor before taking Glycoaish N 0.5mg/2.5mg Injection. Your doctor will weigh the benefits and any potential risks before prescribing it to you.

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Kidney

Caution

If u have or had a history or evidence of any kidney-related diseases, please consult the doctor before taking Glycoaish N 0.5mg/2.5mg Injection. Your doctor will weigh the benefits and any potential risks before prescribing it to you.

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Children

Safe if prescribed

Glycoaish N 0.5mg/2.5mg Injection can be given to children with caution if prescribed by the doctor, the dose depends on the child’s age and weight.

Country of origin

India
Other Info - GL27858

Author Details

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FAQs

Glycoaish N 0.5mg/2.5mg Injection is used to reverse the effects of muscle relaxants and anaesthesia medicines used during surgery.
Glycoaish N 0.5mg/2.5mg Injection contains two medicines namely: Glycopyrrolate and Neostigmine. Neostigmine increases levels of a substance known as acetylcholine by stopping an enzyme required for the breakdown of acetylcholine involved in transmission between nerve impulses and muscle movements. It is used at the end of surgery to reverse the effects of several medicines used during surgery like anesthetics and muscle relaxants. Glycopyrrolate is an anticholinergic It works by blocking the activity of a chemical messenger (acetylcholine) in the brain. It is added to avoid the unwanted effects of neostigmine like stomach acid, excess saliva production and decreased heart rate.
Glycoaish N 0.5mg/2.5mg Injection should be used with caution in the medical history of asthma, breathing problems, stomach ulcers, high temperature, high blood pressure, heart attack, heart disease, overactive thyroid (hypothyroidism). Please let your doctor know if you have any other medical problems before starting Glycoaish N 0.5mg/2.5mg Injection.
Do not stop taking Glycoaish N 0.5mg/2.5mg Injection on your own. To treat your condition effectually please continue taking Glycoaish N 0.5mg/2.5mg Injection for the prescribed period. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Glycoaish N 0.5mg/2.5mg Injection.
Take the missed dose as soon as possible. However, if it is time for the next dose, skip the missed dose and go back to your regular dosing schedule. Do not double the dose.
Keep Glycoaish N 0.5mg/2.5mg Injection in a cool, dry place away from direct sunlight. Dispose of unused medicine and keep it out of sight and reach from children and pets.

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