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About Glotemoz 250mg Capsule

Glotemoz 250mg Capsule belongs to a class of medicines called 'anti-cancer/ antitumor agent', used to treat specific forms of brain tumours such as glioblastoma multiforme (a type of tumour that grows and spreads rapidly) in adults and malignant glioma, including glioblastoma multiforme or anaplastic astrocytoma (a rare malignant brain tumour) in patients older than 3years. A brain tumour is an uncontrolled and unregulated proliferation of cells in the brain. 

Glotemoz 250mg Capsule contains Temozolomide which works by inhibiting the production of DNA (deoxyribonucleic acid-genetic material of the cell), thereby affecting cell growth and division. Thus, Glotemoz 250mg Capsule prevents tumours from growing.

Take Glotemoz 250mg Capsule as prescribed. In some cases, Glotemoz 250mg Capsule may cause loss of appetite, anxiety, confusion, headache, vomiting, nausea, diarrhoea, constipation, muscle weakness, muscle aches, and fever. Most of these side effects of Glotemoz 250mg Capsule do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Let your doctor know if you are allergic to any of the contents. Glotemoz 250mg Capsule is not recommended for patients with severe bone marrow depression or significant bleeding. Avoid taking Glotemoz 250mg Capsule if you are pregnant or breastfeeding. Both women and men using Glotemoz 250mg Capsule should use birth control to avoid pregnancy and fathering a child. It would be best not to drive and/or operate machines that require alertness as Glotemoz 250mg Capsule may cause tiredness or sleepiness.

Uses of Glotemoz 250mg Capsule

Treatment of Brain tumour

Medicinal Benefits

Glotemoz 250mg Capsule belongs to a class of medicines called anti-cancer/antitumor agents used to treat specific forms of brain tumours such as glioblastoma multiforme (a type of tumour that grows and spreads rapidly) in adults and malignant glioma, including glioblastoma multiforme or anaplastic astrocytoma (a rare malignant brain tumour) in patients older than 3years. It contains Temozolomide which works by binding to the DNA (deoxyribonucleic acid-genetic material of the cell) and interfering with cell growth and division. Thus, Glotemoz 250mg Capsule prevents tumours from growing.

Side Effects of Glotemoz 250mg Capsule

  • Loss of appetite
  • Difficulty speaking
  • Headache
  • Vomiting
  • Nausea
  • Diarrhoea
  • Constipation
  • Rash
  • Hair loss
  • Tiredness
  • Infections
  • Fever
  • Increased blood sugar
  • Dry skin
  • Swelling
  • Weight loss/gain
  • Frequent urination

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Glotemoz 250mg Capsule should be taken under strict medical supervision. The doctor will regularly monitor your condition while taking Glotemoz 250mg Capsule. To treat your condition effectually, continue taking Glotemoz 250mg Capsule for as long as your doctor has prescribed. Do not stop Glotemoz 250mg Capsule midway under any circumstances without consulting the healthcare professional. Inform your doctor if you have an allergy to any components of Glotemoz 250mg Capsule. Inform your doctor before taking Glotemoz 250mg Capsule if you have allergic reactions, infections, lung, renal or hepatic disorders or low blood count (including neutropenia, lymphopenia, thrombocytopenia). Glotemoz 250mg Capsule is not recommended for patients with severe bone marrow depression or significant bleeding. Avoid taking Glotemoz 250mg Capsule if you are pregnant or breastfeeding. Both women and men using Glotemoz 250mg Capsule should use birth control to avoid pregnancy or fathering a child. Do not receive any vaccinations or immunizations without your doctor's approval while taking Glotemoz 250mg Capsule.

Therapeutic Class

ANTINEOPLASTIC

Drug Interactions

Drug-Drug Interactions: Glotemoz 250mg Capsule interacts with medicines used to treat infections (e.g. adalimumab), medicines used to treat rheumatoid arthritis (e.g. baricitinib, certolizumab, golimumab, infliximab, leflunomide, upadacitinib), medicines used to treat certain cancers (e.g. cladribine), medicines used to treat mental/mood disorders (e.g. clozapine), medicines used to treat multiple sclerosis (e.g. fingolimod, siponimod, teriflunomide),  cholesterol-lowering medications (e.g. lomitapide), and vaccines (e.g. BCG vaccine, influenza virus vaccine, measles virus vaccine, rotavirus vaccine, rubella virus vaccine smallpox vaccine, typhoid vaccine, varicella virus vaccine, yellow fever vaccine, zoster vaccine).

Drug-Food Interactions: Avoid the consumption of alcohol while taking Glotemoz 250mg Capsule.

Drug-Disease Interactions: Inform your doctor before taking the Glotemoz 250mg Capsule you are suffering from urticaria or allergic reactions, bleeding disorders, myelosuppression (bone marrow depression), low blood counts, hepatic or renal dysfunction or disorders.

Drug-Drug Interactions Checker List

  • ADALIMUMAB
  • BARICITINIB
  • CERTOLIZUMAB
  • GOLIMUMAB
  • INFLIXIMAB
  • LEFLUNOMIDE
  • UPADACITINIB
  • CLADRIBINE
  • CLOZAPINE
  • FINGOLIMOD
  • SIPONIMOD
  • TERIFLUNOMIDE
  • LOMITAPIDE
  • BCG VACCINE
  • INFLUENZA (LIVE ATTENUATED)
  • MEASLES (LIVE ATTENUATED)
  • ROTAVIRUS VACCINE
  • RUBELLA (LIVE ATTENUATED)
  • SMALLPOX VACCINE
  • TYPHOID VACCINE
  • VARICELLA (LIVE ATTENUATED)
  • YELLOW FEVER VACCINE
  • ZOSTER VACCINE LIVE

Diet & Lifestyle Advise

  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Performing yoga may also help in improving both physical and mental health.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs in your diet.
  • Get optimal sleep; rest well.
  • Avoid smoking and alcohol consumption.
  • Avoid fast food, fried food, processed meats, refined carbs and added sugars.

Habit Forming

No

What if I have taken an overdose of Glotemoz 250mg Capsule

Do not take more than the prescribed dose of Glotemoz 250mg Capsule as it may cause overdose. The symptoms of overdose include unusual bleeding or bruising; red/black/tarry stools; red/dark brown/pink urine; coughing up or vomiting blood or material that looks like coffee grounds; sore throat, fever, ongoing congestion and cough, or other signs of infection. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Special Advise

  • Glotemoz 250mg Capsule should be taken under strict medical supervision. The doctor will regularly monitor your condition while taking Glotemoz 250mg Capsule.
  • Your doctor may advise you to get routine blood tests done to monitor your liver function, electrolyte levels, and blood cell count.
  • Both male and female patients who are taking Glotemoz 250mg Capsule must use effective contraceptive precautions. Women of childbearing potential must use effective contraception during the treatment and for 6months after completion of the treatment. Male patients should avoid fathering a child while on treatment with Glotemoz 250mg Capsule and should use effective contraception during the treatment and for 3months after the treatment.

Disease/Condition Glossary

Brain tumour: A brain tumour is an uncontrolled, unregulated proliferation of cells in the brain. The cancerous cells can invade and destroy surrounding healthy tissue, including organs. The symptoms of a brain tumour differ depending on the tumour's location in the brain. Common symptoms include headaches, fits (seizures), feeling unwell or being sick all the time, behavioural changes, paralysis, sickness, eyesight or speech impairments.

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Alcohol

Caution

You are recommended to avoid alcohol consumption while taking Glotemoz 250mg Capsule. It could lead to unpleasant side effects.

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Pregnancy

Caution

Please consult your doctor if you have any concerns about this. Glotemoz 250mg Capsule should not be used during pregnancy unless prescribed by your doctor. Women of childbearing potential must use effective contraception during the treatment and for 6months after completion of the treatment.

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Breast Feeding

Unsafe

Glotemoz 250mg Capsule should not be taken during breastfeeding as it passes into the breastmilk and may harm the baby.

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Driving

Caution

Glotemoz 250mg Capsule may make you feel tired or sleepy. Drive and/or operate machines only if you are alert.

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Liver

Caution

If you have had a history or evidence of any liver-related diseases, please consult the doctor before using Glotemoz 250mg Capsule. Your doctor will weigh the benefits and potential risks before prescribing Glotemoz 250mg Capsule.

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Kidney

Caution

If you have had a history or evidence of any kidney-related diseases, please consult the doctor before using Glotemoz 250mg Capsule. Your doctor will weigh the benefits and potential risks before prescribing Glotemoz 250mg Capsule.

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Children

Caution

Safety and effectiveness of Glotemoz 250mg Capsule in paediatric patients under the age of three have not been established.

Country of origin

India
Other Info - GL56876

Author Details

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FAQs

Glotemoz 250mg Capsule belongs to a class of medicines called anti-cancer agents, used to treat specific forms of brain tumours such as glioblastoma multiforme (a type of tumour that grows and spreads rapidly) in adults and malignant glioma, including glioblastoma multiforme or anaplastic astrocytoma (a rare malignant brain tumour) in patients older than 3years.
Glotemoz 250mg Capsule works by binding to the DNA (deoxyribonucleic acid-genetic material of the cell) and interfering with cell growth and division. Thus, Glotemoz 250mg Capsule prevents tumours from growing.
Glotemoz 250mg Capsule may cause permanent infertility. Male patients should use effective contraception and refrain from fathering a child for up to three months after treatment is completed. Prior to treatment, it is recommended to seek sperm conservation advice from your doctor.
Yes, Glotemoz 250mg Capsule can cause neutropenia (low white blood cells count), lymphopenia (low lymphocytes count), thrombocytopenia (low platelet count). As a part of therapy, your doctor may monitor your blood profile.
Glotemoz 250mg Capsule may lead to hyperglycemia (Increased blood sugar). Consult your doctor if you are diabetic. Regularly monitor your blood sugar levels while taking Glotemoz 250mg Capsule.
The live vaccine may interact with Glotemoz 250mg Capsule. Do not have vaccinations or immunisations without talking to your doctor first.

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